p38 MAPK and ERK activation by 9-cis-retinoic acid induces chemokine receptors CCR1 and CCR2 expression in human monocytic THP-1 cells

Experimental and Molecular Medicine

Volumn 39, Issue 2, 2007, Pages 129-138

  Ko, Jesang ^a   Yun, Chi Young ^b   Lee, Ji Sook ^b   Kim, Joo Hwan ^b   In, Sik Kim ^c  

^a Korea University   (South Korea)

^b Daejeon University   (South Korea)

^c Eulji University   (South Korea)

Author keywords

Chemotaxis; Extracellular signal regulated MAP kinases; Monocytes; p38 mitogen activated protein kinases; Receptors, chemokine; Retinoids

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALITRETINOIN; CHEMOKINE; CHEMOKINE CCL15; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MEMBRANE PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MONOCYTE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 34247570008     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2007.15     Document Type: Article

References (25)

1. Antonyak MA, McNeill CJ, Wakshlag JJ, Boehm JE, Cerione RA. Activation of the Ras-ERK pathway inhibits retinoic acid-induced stimulation of tissue transglutaminase expression in NIH3T3 cells. J Bio Chem 2003;278:15859-66
2. Ashida N, Arai H, Yamasaki M, Kita T. Distinct signaling pathways for MCP-1-dependent integrin activation and chemotaxis. J Bio Chem 2001;276:16555-60
3. Baggiolini M, Dewald B, Moser B. Human chemokines: an update. Annu Rev Immunol 1997;15:675-705
4. Bost F, Caron L, Marchetti I, Dani C, Le Marchand-Brustel Y, Binetruy B. Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage. Biochem J 2002;361:621-27
5. Cambien B, Pomeranz M, Millet MA, Rossi B, Schmid-Alliana A. Signal transduction involved in MCP-1-mediated monocytic transendothelial migration. Blood 2001;97:359-66
6. -/- mice: the role of mast cells. J Immunol 1999;63:2160-7
7. Evans RM. The steroid and thyroid hormone receptor superfamily. Science 1988;240:889-95
8. Felli MP, Vacca A, Meco D, Screpanti I, Farina AR, Maroder M, Martinotti S, Petrangeli E, Frati L, Gulino A. Retinoic acid-induced down-regulation of the interleukin-2 promoter via cis-regulatory sequences containing an octamer motif. Mol Cell Biol 1991;11:4771-8
9. Feoktistov I, Goldstein AE, Biaggioni I. Role of p38 mitogen-activated protein kinase and extracellular signal-regulated protein kinase kinase in adenosine A2B receptor-mediated interleukin-8 production in human mast cells. Mol Pharmacol 1999;55:726-34
10. Hong HY, Varvayanis S, Yen A. Retinoic acid causes MEK-dependent RAF phosphorylation through RARalpha plus RXR activation in HL-60 cells. Differentiation 2001;68:55-66
11. Kim IS, Ryang YS, Kim YS, Jang SW, Sung HJ, Lee YH, Kim J, Na DS, Ko J. Leukotactin-1-induced ERK activation is mediated via Gi/Go protein/PLC/PKC delta/Ras cascades in HOS cells. Life Sci 2003;73:447-59
12. Kim IS, Kim YS, Jang SW, Sung HJ, Han KH, Na DS, Ko J. Differential effects of 9-cis retinoic acid on expression of CC chemokine receptors in human monocytes. Biochem Pharmacol 2004;68:611-20
13. Kim IS, Jang SW, Sung HJ, Lee JS, Ko J. Differential CCR1-mediated chemotaxis signaling induced by human CC chemokine HCC-4/CCL16 in HOS cells. FEBS Lett 2005;579:6044-8
14. Li H, Cheung W, Choo HH, Chan JH, Lai PS, Fred Wong WS. IL-10 synergistically enhances GM-CSF-induced CCR1 expression in myelomonocytic cells. Biochem Biophys Res Commun 2003;304:417-24
15. Luster AD. Mechanisms of disease: chemokines-chemotactic cytokines that mediate inflammation. N Eng J Med 1998;338:436-45
16. Parker LC, Whyte MK, Vogel SN, Dower SK, Sabroe I. Toll-like receptor (TLR)2 and TLR4 agonists regulate CCR expression in human monocytic cells. J Immunol 2004;172:4977-86
17. Phillips RM, Stubbs VE, Henson MR, Williams TJ, Pease JE, Sabroe I. Variations in eosinophil chemokine responses: an investigation of CCR1 and CCR3 function, expression in atopy, and identification of a functional CCR1 promoter. J Immunol 2003;170:6190-201
18. Rollins BJ. Chemokines. Blood 1997;90:909-28
19. Stephensen CB, Vitamin A. infection, and immune function. Annu Rev Nutr 2001;21:167-92
20. Teruel T, Hernandez R, Benito M, Lorenzo M. Rosiglitazone and retinoic acid induce uncoupling protein-1 (UCP-1) in a p38 mitogen-activated protein kinase-dependent manner in fetal primary brown adipocytes. J Biol Chem 2003;278:263-9
21. Trebst C, Sorensen TL, Kivisakk P, Cathcart MK, Hesselgesser J, Horuk R, Sellebjerg F, Lassmann H, Ransohoff RM. CCR1+/CCR5+ mononuclear phagocytes accumulate in the central nervous system of patients with multiple sclerosis. Am J Pathol 2001;159:1701-10
22. Yen A, Fenning R, Chandraratna R, Walker P, Varvayanis S. A retinoic acid receptor beta/gamma-selective prodrug (tazarotene) plus a retinoid X receptor ligand induces extracellular signal-regulated kinase activation, retinoblastoma hypophosphorylation, G0 arrest, and cell differentiation. Mol Pharmacol 2004;66:1727-37
23. Zella D, Barabitskaja O, Burns JM, Romerio F, Dunn DE, Revello MG, Gerna G, Reitz MS Jr. Gallo RC, Weichold FF. Interferon-γ increases expression of chemokine receptors CCR1, CCR3, and CCR5, but not CXCR4 in monocytoid U937 cells. Blood 1998;91:4444-50
24. Zella D, Barabitskaja O, Casareto L, Romerio F, Secchiero P, Reitz MS Jr. Gallo RC, Weichold FF. Recombinant IFN-α (2b) increases the expression of apoptosis receptor CD95 and chemokine receptors CCR1 and CCR3 in monocytoid cells. J Immunol 1999;163:3169-75
25. Zhou XF, Shen XQ, Shemshedini L. Ligand-activated retinoic acid receptor inhibits AP-1 transactivation by disrupting c-Jun/c-Fos dimerization. Mol Endocrinol 1999;13:276-85