-
1
-
-
77957361348
-
Development trends for human monoclonal antibody therapeutics
-
Nelson AL, Dhimolea E, Reichert JM (2010) Development trends for human monoclonal antibody therapeutics. Nat Rev Drug Discov 9:767-774
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 767-774
-
-
Nelson, A.L.1
Dhimolea, E.2
Reichert, J.M.3
-
2
-
-
84863774072
-
Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses
-
Burton DR, Poignard P, Stanfi eld RL et al (2012) Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses. Science 337:183-186
-
(2012)
Science
, vol.337
, pp. 183-186
-
-
Burton, D.R.1
Poignard, P.2
Stanfield, R.L.3
-
3
-
-
79960976700
-
Antibody fragments as tools in crystallography
-
Griffin L, Lawson A (2011) Antibody fragments as tools in crystallography. Clin Exp Immunol 165:285-291
-
(2011)
Clin Exp Immunol
, vol.165
, pp. 285-291
-
-
Griffin, L.1
Lawson, A.2
-
4
-
-
0017411710
-
The Protein Data Bank: A computerbased archival fi le for macromolecular structures
-
Bernstein FC, Koetzle TF, Williams GJ et al (1977) The Protein Data Bank: a computerbased archival fi le for macromolecular structures. J Mol Biol 112:535-542
-
(1977)
J Mol Biol
, vol.112
, pp. 535-542
-
-
Bernstein, F.C.1
Koetzle, T.F.2
Williams, G.J.3
-
5
-
-
0019119230
-
Crystallographic refi nement and atomic models of the intact immunoglobulin molecule Kol and its antigen-binding fragment at 3.0 Å and 1.9 Å resolution
-
Marquart M, Deisenhofer J, Huber R et al (1980) Crystallographic refi nement and atomic models of the intact immunoglobulin molecule Kol and its antigen-binding fragment at 3.0 Å and 1.9 Å resolution. J Mol Biol 141: 369-391
-
(1980)
J Mol Biol
, vol.141
, pp. 369-391
-
-
Marquart, M.1
Deisenhofer, J.2
Huber, R.3
-
6
-
-
0026679890
-
The three-dimensional structure of an intact monoclonal antibody for canine lymphoma
-
Harris LJ, Larson SB, Hasel KW et al (1992) The three-dimensional structure of an intact monoclonal antibody for canine lymphoma. Nature 360:369-372
-
(1992)
Nature
, vol.360
, pp. 369-372
-
-
Harris, L.J.1
Larson, S.B.2
Hasel, K.W.3
-
7
-
-
0031017896
-
Refined structure of an intact IgG2a monoclonal antibody
-
Harris LJ, Larson SB, Hasel KW et al (1997) Refined structure of an intact IgG2a monoclonal antibody. Biochemistry 36:1581-1597
-
(1997)
Biochemistry
, vol.36
, pp. 1581-1597
-
-
Harris, L.J.1
Larson, S.B.2
Hasel, K.W.3
-
8
-
-
0032488888
-
Crystallographic structure of an intact IgG1 monoclonal antibody
-
Harris LJ, Skaletsky E, McPherson A (1998) Crystallographic structure of an intact IgG1 monoclonal antibody. J Mol Biol 275:861-872
-
(1998)
J Mol Biol
, vol.275
, pp. 861-872
-
-
Harris, L.J.1
Skaletsky, E.2
McPherson, A.3
-
9
-
-
17944380435
-
Crystal structure of a neutralizing human IGG against HIV-1: A template for vaccine design
-
Saphire EO, Parren PW, Pantophlet R et al (2001) Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design. Science 293:1155-1159
-
(2001)
Science
, vol.293
, pp. 1155-1159
-
-
Saphire, E.O.1
Parren, P.W.2
Pantophlet, R.3
-
10
-
-
0026326784
-
X-ray crystallographic analysis of free and antigen-complexed Fab fragments to investigate structural basis of immune recognition
-
Wilson IA, Rini JM, Fremont DH et al (1991) X-ray crystallographic analysis of free and antigen-complexed Fab fragments to investigate structural basis of immune recognition. Methods Enzymol 203:153-176
-
(1991)
Methods Enzymol
, vol.203
, pp. 153-176
-
-
Wilson, I.A.1
Rini, J.M.2
Fremont, D.H.3
-
11
-
-
0027752197
-
Purification of mouse antibodies and Fab fragments
-
Smith TJ (1993) Purification of mouse antibodies and Fab fragments. Methods Cell Biol 37:75-93
-
(1993)
Methods Cell Biol
, vol.37
, pp. 75-93
-
-
Smith, T.J.1
-
12
-
-
0002709543
-
Crystallization of antibodies and antibodyantigen complexes
-
Stura EA, Fieser GG, Wilson IA (1993) Crystallization of antibodies and antibodyantigen complexes. Immunomethods 3: 164-179
-
(1993)
Immunomethods
, vol.3
, pp. 164-179
-
-
Stura, E.A.1
Fieser, G.G.2
Wilson, I.A.3
-
13
-
-
10644265996
-
Structure of the streptococcal endopeptidase IdeS, a cysteine proteinase with strict specificity for IgG
-
Wenig K, Chatwell L, von Pawel-Rammingen U et al (2004) Structure of the streptococcal endopeptidase IdeS, a cysteine proteinase with strict specificity for IgG. Proc Natl Acad Sci U S A 101:17371-17376
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 17371-17376
-
-
Wenig, K.1
Chatwell, L.2
Von Pawel-Rammingen, U.3
-
14
-
-
4544379899
-
Structure and mechanistic analysis of the antihuman immunodefi ciency virus type 1 antibody 2 F5 in complex with its gp41 epitope
-
Ofek G, Tang M, Sambor A et al (2004) Structure and mechanistic analysis of the antihuman immunodefi ciency virus type 1 antibody 2 F5 in complex with its gp41 epitope. J Virol 78:10724-10737
-
(2004)
J Virol
, vol.78
, pp. 10724-10737
-
-
Ofek, G.1
Tang, M.2
Sambor, A.3
-
15
-
-
38749149916
-
Protein crystallization: From purified protein to diffractionquality crystal
-
Chayen NE, Saridakis E (2008) Protein crystallization: from purified protein to diffractionquality crystal. Nat Methods 5:147-153
-
(2008)
Nat Methods
, vol.5
, pp. 147-153
-
-
Chayen, N.E.1
Saridakis, E.2
-
16
-
-
0026117693
-
The streak seeding technique in protein crystallization
-
Stura EA, Wilson IA (1991) The streak seeding technique in protein crystallization. J Cryst Growth 110:270-282
-
(1991)
J Cryst Growth
, vol.110
, pp. 270-282
-
-
Stura, E.A.1
Wilson, I.A.2
-
17
-
-
7444264009
-
Microseed matrix screening to improve crystals of yeast cytosine deaminase
-
Ireton GC, Stoddard BL (2004) Microseed matrix screening to improve crystals of yeast cytosine deaminase. Acta Crystallogr D Biol Crystallogr 60:601-605
-
(2004)
Acta Crystallogr D Biol Crystallogr
, vol.60
, pp. 601-605
-
-
Ireton, G.C.1
Stoddard, B.L.2
-
18
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Otwinowski Z, Minor W (1997) Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol 276A:307-326
-
(1997)
Methods Enzymol
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
20
-
-
71649092785
-
Processing diffraction data with Mosflm
-
Read RJ, Sussman JL (eds) Springer, Netherlands
-
Leslie AGW, Powell HR (2007) Processing diffraction data with Mosflm. In: Read RJ, Sussman JL (eds) Evolving methods for macromolecular crystallography, vol 245, Springer, Netherlands, pp 41-51
-
(2007)
Evolving Methods for Macromolecular Crystallography
, vol.245
, pp. 41-51
-
-
Leslie, A.G.W.1
Powell, H.R.2
-
21
-
-
0033213239
-
The finer things in X-ray diffraction data collection
-
Pflugrath JW (1999) The fi ner things in X-ray diffraction data collection. Acta Crystallogr D Biol Crystallogr 55:1718-1725
-
(1999)
Acta Crystallogr D Biol Crystallogr
, vol.55
, pp. 1718-1725
-
-
Pflugrath, J.W.1
-
22
-
-
70450224882
-
Light chain somatic mutations change thermodynamics of binding and water coordination in the HyHEL-10 family of antibodies
-
Acchione M, Lipschultz CA, DeSantis ME et al (2009) Light chain somatic mutations change thermodynamics of binding and water coordination in the HyHEL-10 family of antibodies. Mol Immunol 47:457-464
-
(2009)
Mol Immunol
, vol.47
, pp. 457-464
-
-
Acchione, M.1
Lipschultz, C.A.2
Desantis, M.E.3
-
24
-
-
33645049294
-
Antibody elbow angles are influenced by their light chain class
-
Stanfi eld RL, Zemla A, Wilson IA et al (2006) Antibody elbow angles are influenced by their light chain class. J Mol Biol 357:1566-1574
-
(2006)
J Mol Biol
, vol.357
, pp. 1566-1574
-
-
Stanfield, R.L.1
Zemla, A.2
Wilson, I.A.3
-
26
-
-
84920325457
-
AMoRe: An automated package for molecular replacement
-
Navaza J (1994) AMoRe: an automated package for molecular replacement. Acta Crystallogr A 50:157-163
-
(1994)
Acta Crystallogr A
, vol.50
, pp. 157-163
-
-
Navaza, J.1
-
31
-
-
37049014272
-
Version 1.2 of the crystallography and NMR system
-
Brunger AT (2007) Version 1.2 of the crystallography and NMR system. Nat Protoc 2:2728-2733
-
(2007)
Nat Protoc
, vol.2
, pp. 2728-2733
-
-
Brunger, A.T.1
-
32
-
-
14844321328
-
Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT
-
Blanc E, Roversi P, Vonrhein C et al (2004) Refi nement of severely incomplete structures with maximum likelihood in BUSTER-TNT. Acta Crystallogr D Biol Crystallogr 60:2210-2221
-
(2004)
Acta Crystallogr D Biol Crystallogr
, vol.60
, pp. 2210-2221
-
-
Blanc, E.1
Roversi, P.2
Vonrhein, C.3
-
33
-
-
0030577371
-
Structural classifi cation of CDR-H3 in antibodies
-
Shirai H, Kidera A, Nakamura H (1996) Structural classifi cation of CDR-H3 in antibodies. FEBS Lett 399:1-8
-
(1996)
FEBS Lett
, vol.399
, pp. 1-8
-
-
Shirai, H.1
Kidera, A.2
Nakamura, H.3
-
34
-
-
58849161361
-
On vital aid: The why, what and how of validation
-
Kleywegt GJ (2009) On vital aid: the why, what and how of validation. Acta Crystallogr D Biol Crystallogr 65:134-139
-
(2009)
Acta Crystallogr D Biol Crystallogr
, vol.65
, pp. 134-139
-
-
Kleywegt, G.J.1
-
35
-
-
0013014016
-
-
5th edn. U.S. Department of Health and Human Services, Bethesda, MD
-
Kabat EA, Wu TT, Perry HM et al (1991) Sequences of proteins of immunological interest, vol 1, 5th edn. U.S. Department of Health and Human Services, Bethesda, MD
-
(1991)
Sequences of Proteins of Immunological Interest
, vol.1
-
-
Kabat, E.A.1
Wu, T.T.2
Perry, H.M.3
-
37
-
-
0031558798
-
Standard conformations for the canonical structures of immunoglobulins
-
Al-Lazikani B, Lesk AM, Chothia C (1997) Standard conformations for the canonical structures of immunoglobulins. J Mol Biol 273:927-948
-
(1997)
J Mol Biol
, vol.273
, pp. 927-948
-
-
Al-Lazikani, B.1
Lesk, A.M.2
Chothia, C.3
-
38
-
-
0023278330
-
Canonical structures for the hypervariable regions of immunoglobulins
-
Chothia C, Lesk AM (1987) Canonical structures for the hypervariable regions of immunoglobulins. J Mol Biol 196:901-917
-
(1987)
J Mol Biol
, vol.196
, pp. 901-917
-
-
Chothia, C.1
Lesk, A.M.2
-
39
-
-
0030589039
-
Structural families in loops of homologous proteins: Automatic classifi cation, modelling and application to antibodies
-
Martin AC, Thornton JM (1996) Structural families in loops of homologous proteins: automatic classifi cation, modelling and application to antibodies. J Mol Biol 263:800-815
-
(1996)
J Mol Biol
, vol.263
, pp. 800-815
-
-
Martin, A.C.1
Thornton, J.M.2
-
40
-
-
79251598995
-
A new clustering of antibody CDR loop conformations
-
North B, Lehmann A, Dunbrack RL Jr (2011) A new clustering of antibody CDR loop conformations. J Mol Biol 406:228-256
-
(2011)
J Mol Biol
, vol.406
, pp. 228-256
-
-
North, B.1
Lehmann, A.2
Dunbrack Jr., R.L.3
-
41
-
-
0027109248
-
Strategies in the crystallization of glycoproteins and protein complexes
-
Stura EA, Nemerow GR, Wilson IA (1992) Strategies in the crystallization of glycoproteins and protein complexes. J Cryst Growth 122:273-285
-
(1992)
J Cryst Growth
, vol.122
, pp. 273-285
-
-
Stura, E.A.1
Nemerow, G.R.2
Wilson, I.A.3
-
42
-
-
0027482860
-
Structural consequences of reductive methylation of lysine residues in hen egg white lysozyme: An X-ray analysis at 1.8-Å resolution
-
Rypniewski WR, Holden HM, Rayment I (1993) Structural consequences of reductive methylation of lysine residues in hen egg white lysozyme: an X-ray analysis at 1.8-Å resolution. Biochemistry 32:9851-9858
-
(1993)
Biochemistry
, vol.32
, pp. 9851-9858
-
-
Rypniewski, W.R.1
Holden, H.M.2
Rayment, I.3
-
44
-
-
0000449985
-
Glycerol concentrations required for cryoprotection of 50 typical protein crystallization conditions
-
Garman EF, Mitchell EP (1996) Glycerol concentrations required for cryoprotection of 50 typical protein crystallization conditions. J Appl Crystallogr 29:584-587
-
(1996)
J Appl Crystallogr
, vol.29
, pp. 584-587
-
-
Garman, E.F.1
Mitchell, E.P.2
-
45
-
-
36549085048
-
Cryocrystallography of macromolecules: Practice and optimization
-
Garman E, Owen RL (2007) Cryocrystallography of macromolecules: practice and optimization. Methods Mol Biol 364: 1-18
-
(2007)
Methods Mol Biol
, vol.364
, pp. 1-18
-
-
Garman, E.1
Owen, R.L.2
-
46
-
-
36549087672
-
X-ray data collection from macromolecular crystals
-
Garman E, Sweet RM (2007) X-ray data collection from macromolecular crystals. Methods Mol Biol 364:63-94
-
(2007)
Methods Mol Biol
, vol.364
, pp. 63-94
-
-
Garman, E.1
Sweet, R.M.2
-
47
-
-
79952109556
-
Computational tools in protein crystallography
-
Jain D, Lamour V (2010) Computational tools in protein crystallography. Methods Mol Biol 673:129-156
-
(2010)
Methods Mol Biol
, vol.673
, pp. 129-156
-
-
Jain, D.1
Lamour, V.2
-
48
-
-
48049124972
-
Analysis and improvements to Kabat and structurally correct numbering of antibody variable domains
-
Abhinandan KR, Martin AC (2008) Analysis and improvements to Kabat and structurally correct numbering of antibody variable domains. Mol Immunol 45:3832-3839
-
(2008)
Mol Immunol
, vol.45
, pp. 3832-3839
-
-
Abhinandan, K.R.1
Martin, A.C.2
|