The quality and validation of structures from structural genomics

Methods in Molecular Biology

Volumn 1091, Issue , 2014, Pages 297-314

  Domagalski, Marcin J ^a   Zheng, Heping ^a   Zimmerman, Matthew D ^a   Dauter, Zbigniew ^b   Wlodawer, Alexander ^c   Minor, Wladek ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b ARGONNE NATIONAL LABORATORY   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Data mining; Drug discovery; Structural genomics; Structure quality; Structure validation

Indexed keywords

ARTICLE; AUTOMATION; COMPLEX FORMATION; CRYSTAL STRUCTURE; DATA MINING; DIFFRACTION; HIGH THROUGHPUT SCREENING; LIGAND BINDING; MACROMOLECULE; MODEL; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DATA BANK; QUALITY CONTROL; STANDARD; STRUCTURAL GENOMICS; STRUCTURE ANALYSIS; VALIDATION PROCESS; VALIDITY; WATER STRUCTURE; X RAY CRYSTALLOGRAPHY; ELECTRON MICROSCOPY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; QUALITATIVE ANALYSIS; STRUCTURAL MODEL; VALIDATION STUDY; X RAY DIFFRACTION;

LIGAND; PROTEIN;

DATA MINING; DATABASES, PROTEIN; LIGANDS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEINS; PROTEOMICS; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS;

EID: 84934444014     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-691-7_21     Document Type: Article

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