Enzyme kinetics, inhibition, and regioselectivity of aldehyde oxidase

Methods in Molecular Biology

Volumn 1113, Issue , 2014, Pages 167-186

  Barr, John T ^a   Choughule, Kanika ^a   Jones, Jeffrey P ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Aldehyde oxidase; Computational predictions; DACA; Drug metabolism; Drug drug interactions; Inhibition; Nitric oxide; Pharmacokinetics; Reactive oxygen species

Indexed keywords

6 (2 AMINO 4 PHENYLPYRIMIDIN 5 YL) 2 ISOPROPYLPYRIDAZIN 3(2H)ONE; 6 [6 (1 METHYL 1H PYRAZOL 4 YL) [1,2,4]TRIAZOLO[4,3 B]PYRIDAZIN 3 YLTHIO]QUINOLINE; ADENOSINE A1 RECEPTOR ANTAGONIST; ALDEHYDE OXIDASE; CYTOKINE RECEPTOR ANTAGONIST; FK 3453; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; REACTIVE OXYGEN METABOLITE; SGX 523; SUPEROXIDE; UNCLASSIFIED DRUG;

ARTICLE; BIOCHEMISTRY; DRUG METABOLISM; ENZYME CHEMISTRY; ENZYME INHIBITION; ENZYME KINETICS; HUMAN; INHIBITION KINETICS; NONHUMAN; OXIDATIVE STRESS; PHASE 1 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; TISSUE INJURY;

ALDEHYDE OXIDASE; ANIMALS; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; ENZYME INHIBITORS; HUMANS; KINETICS; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 84934443686     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-758-7_9     Document Type: Article

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