Improved methods of retroviral vector transduction and production for gene therapy

Human Gene Therapy

Volumn 5, Issue 1, 1994, Pages 19-28

  Kotani, Hitoshi ^a   Newton III, Perry B ^a   Zhang, Shuyuan ^a   Chiang, Yawen L ^a   Otto, Edward ^a   Weaver, Linda ^a   Blaese, R Michael ^b   Anderson, W French ^c   McGarrity, Gerard J ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GELATIN; GLUCOSE; SORBITOL;

ARTICLE; CELL CULTURE; CELL GROWTH; CELL LINE; CLONING VECTOR; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTER; GENE THERAPY; GENE TRANSFER; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; RETROVIRUS;

UNIDENTIFIED RETROVIRUS;

EID: 0028076782     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1994.5.1-19     Document Type: Article

References (34)

1. ANDERSON, W.F., BLAESE, R.M., and CULVER, K. (1990). The ADA gene therapy clinical protocol. Hum. Gene Ther. 1, 331-362.
2. BENNETT, P.S., MAIGETTER, R.Z., OLSON, M.G., PROVOST, P.J., SCATTERGOOD, E.M., and SCHOFIELD, T.L. (1991) The effects of freeze-drying on the potency and stability of live varicella virus vaccine. Develop. Biol. Standard. 74, 215-221.
3. CENTER FOR BIOLOGICS EVALUATION AND RESEARCH. (1991). The Food and Drug Administration. Points to Consider in Human Somatic Cell Therapy and Gene Therapy. Hum. Gene Ther. 2, 251-256.
4. CORNETTA, K., MOEN, R.C., CULVER, K , MORGAN, R.A., McLACHLIN, J.R., STURM, S., SELEGUE, J., LONDON, W., BLAESE, R.M., and ANDERSON, W.F. (1990). Amphotropic murine leukemia retrovirus is not an acute pathogen for primates. Hum. Gene Ther. 1, 15-30.
5. CORNETTA, K., MORGAN, R.A., and ANDERSON, W.F. (1991). Safety issues related to retroviral-mediated gene transfer in humans. Hum. Gene Ther. 2, 5-14.
6. CORNETTA, K., MORGAN, R.A., GILLIO, A., STURM, S., BALTRUCKI, L., O'REILLY, R., and ANDERSON, W.F. (1991). No retroviremia or pathology in long-term follow-up of monkeys exposed to a murine amphotropic retrovirus. Hum. Gene Ther. 2, 215-220.
7. CULVER, K.W., RAM, Z., WALLBRIDGE, S., ISHII, H., OLDFIELD, E.H., and BLAESE, R.M. (1992). In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 256, 1550-1552.
8. DANOS, O., and MULLIGAN, R.C. (1988). Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges. Proc. Natl. Acad. Sci, USA 85, 6460-6464.
9. DONAHUE, R.E., KESSLER, S.W., BODINE, D., McDONAGH, K., DUNBAR, C., GOODMAN, S., AGRICOLA, B., BYRNE, E., RAFFELD. M., MOEN, R.C., BACHER, J., ZSEBO, K.M., and NIENHUIS, A. W. (1992) Helper virus induced T-cell lymphoma in nonhuman primates after retroviral mediated gene transfer. J. Exp. Med. 176, 1125-1135.
10. ENDICOTT, J.A., and LING, V. (1989). The biochemistry of P-glycoprotein-mediated multidrug resistance. Ann. Rev. Biochem. 58, 137-171.
11. GOOTENBERG, J.E., RUSCETTI, F.W., MIER, J.W., GAZDARA, A., and GALLO, R.C. (1981). Human cutaneous T-cell lymphoma and leukemia cell lines produce and respond to T-cell growth factor. J. Exp. Med 154, 1403-1418
12. GROSSMAN, M., and WILSON, M. (1992). Frontiers in gene therapy: LDL receptor replacement for hypercholesterolemia. J. Lab. Clin. Med. 119, 457-460.
13. HEGGIE, A.D., and HUANG, Y.T. (1993). Rapid detection of herpes simplex virus in culture by in situ hybridization. J. Virol. Methods 41, 1-7.
14. HOCK, R.A., MILLER, A.D., and OSBORNE, W.R.A (1989). Expression of human adenosine deaminase from various strong promoters after gene transfer into human hematopoietic cell lines. Blood 74, 876-881.
15. JUST, I., and FINKE, H. ( 1979). A contribution to the stabilisation of the MVA-vaccine. Zbl. Bakt. Hyg., I. Abt. Orig A. 245, 276-282.
16. KESSEL, D , BECK, W.T., KUKURUGA D., and SCHULZ, V. (1991). Characterization of multidrug resistance by fluorescent dyes. Cancer Res. 51, 4665-4670.
17. LEVY, J.A., and FIELDSTEEL H. (1982). Freeze-drying is an effective method for preserving infectious type C retroviruses. J. Virol. Methods 5, 165-171.
18. MILLER, A.D. (1992). Retroviral vectors. Curr. Top. Microbiol. Immunol. 158, 1-24.
19. MILLER, A.D., and BUTTIMORE, C. (1986). Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production. Mol. Cell Biol. 6, 2895-2902.
20. MILLER, A.D., and ROSMAN, G.J. (1989). Improved retroviral vectors for gene transfer and expression. BioTechniques 7, 980-990.
21. MILLER, A.R., SKOTZKO, M.J., RHOADES, K., BELLDEGRUN, A.S., TSO, C.-L., KABOO, R., MCBRIDE, W.H., JACOBS, E., KOHN, D.B., MOEM, R., and ECONOMOU, J.S. (1992). Simultaneous use of two retroviral vectors in human gene marking trials: feasibility and potential applications. Hum. Gene Ther. 3, 619-624.
22. MUENCHAU, D.D., FREEMAN, S.M., CORNETTA, K., ZWEIBEL, J.A., and ANDERSON, W.F. (1990). Analysis of retroviral packaging lines for generation of replication-competent virus. Virology 176, 262-265.
23. NIH RECOMBINANT DNA ADVISORY COMMITTEE. (1990). The National Institutes of Health. Points to Consider in the Design and Submission of Protocols for the Transfer of Recombinant DNA in to the Genome of Human Subjects. Hum. Gene Ther. 1, 93-103.
24. PALMER, T.D., THOMPSON, A.R., and MILLER, A.D. (1989). Production of human factor IX in animals by genetically modified skin fibroblasts: Potential therapy for hemophilia B Blood 73, 438-445.
25. PAUL, R.W., MORRIS, D., DUNN, J., GRABSTEIN, K.H., HESS, B.W., and OVERELL, R.W. (1992). Increases in retroviral titer by concentration of virions harvested from retroviral packaging lines. Third International Symposium of Catalytic RNAs (Ribozymes) and Targeted Gene Therapy for Treatment of HIV infection, Abstract, December 6-11. San Diego, California.
26. + HIV-specific T cells for HIV seropositive patients undergoing allogeneie bone marrow transplant. Hum. Gene Ther. 3, 319-338.
27. RIPA, K.T., and MARDH, P.A. (1977). New simplified culture technique for Chlamydia trachomatis. In Nongonococcal Urethritis and Related Infections. K.K. Holmes and D. Hobson, eds. (American Society for Microbiology, Washington, DC) pp. 323-327.
28. ROSENBERG, S.A., AEBERSOLD, P., CORNETTA, K., KASED, A., MORGAN, R.A., MOEN, R.C., KARSON, E.M., LOTZE, M.T., YANG, J.C., TOPALIAN, S.L., MERINO, M.J., CULVER, K., MILLER, A.D., BLAESE, R.M., and ANDERSON, W.F. (1990). Gene transfer into humans - immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction. N. Engl. J. Med. 323, 570-578.
29. ROUSCULP, M.D., GOLDSMITH, K.T., and CARVER, P.I. (1992). Quantitative evaluation of retroviral gene transduction efficiency in human lung cancer cells. Hum. Gene Ther. 3, 471-477.
30. RUNSTADLER, P.W., and YOUNG, M.W. (1991). GMP production of biopharmaceuticals using high density, fluidized-bed cell culture technology. In Animal Cell Culture and Production of Biologicals. S. Sasaki and K. Ikura, eds. (Kluwer Academic Publishers, Dordrecht) pp. 103-119.
31. SANES, J.R , RUBENSTEIN, J.L., and NICOLAS, J.F. (1986). Use of a recombmant retrovirus to study post-implantation cell lineage in mouse embryos. EMBO J. 5, 3133-3142.
32. WEI, C.M., GIBSON, M , SPEAR, P.O., and SCOLNICK, E.M. (1981). Construction and isolation of a transmissible retrovirus containing the src gene of Harvey murine sarcome virus and the thymidine kinase gene of herpes simples virus type 1. J. Virol. 39, 935-944.
33. WEISS, R. (1984). Experimental biology and assay of RNA tumor viruses. In RNA Tumor Viruses. R. Weiss, N. Teich, II. Varmus, and J. Coffin, eds. (Cold Spring Harbor Laboratory, Cold Spring Harbor, NY) pp. 209-260.
34. ZHANG, S., HANDA-CORRIGAN, A., and SPIER, R.E (1993). Kinetics of cell metabolism and antibody production in high concentration perfusion cultures. Proceedings of the 5th Annual Meeting of Japanese Association of Animal Cell Technology (in press).