-
2
-
-
63049090100
-
Metastasis: from dissemination to organ-specific colonization
-
Nguyen DX, Bos PD, Massague J. Metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer. 2009; 9:274-284.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 274-284
-
-
Nguyen, D.X.1
Bos, P.D.2
Massague, J.3
-
6
-
-
85047689195
-
Fibulin-5 function during tumorigenesis
-
Albig AR, Schiemann WP. Fibulin-5 function during tumorigenesis. Future Oncol. 2005; 1:23-35.
-
(2005)
Future Oncol
, vol.1
, pp. 23-35
-
-
Albig, A.R.1
Schiemann, W.P.2
-
8
-
-
0037050030
-
Fibulin-5/DANCE is essential for elastogenesis in vivo
-
Nakamura T, Lozano PR, Ikeda Y, Iwanaga Y, Hinek A, Minamisawa S, Cheng CF, Kobuke K, Dalton N, Takada Y, Tashiro K, Ross J Jr, Honjo T, Chien KR. Fibulin-5/DANCE is essential for elastogenesis in vivo. Nature. 2002; 415:171-175.
-
(2002)
Nature
, vol.415
, pp. 171-175
-
-
Nakamura, T.1
Lozano, P.R.2
Ikeda, Y.3
Iwanaga, Y.4
Hinek, A.5
Minamisawa, S.6
Cheng, C.F.7
Kobuke, K.8
Dalton, N.9
Takada, Y.10
Tashiro, K.11
Ross, J.12
Honjo, T.13
Chien, K.R.14
-
9
-
-
72949119124
-
Integrins in cancer: biological implications and therapeutic opportunities
-
Desgrosellier JS, Cheresh DA. Integrins in cancer: biological implications and therapeutic opportunities. Nat Rev Cancer. 2010; 10:9-22.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 9-22
-
-
Desgrosellier, J.S.1
Cheresh, D.A.2
-
10
-
-
38849145619
-
Downregulation of Dkk3 activates beta-catenin/TCF-4 signaling in lung cancer
-
Yue W, Sun Q, Dacic S, Landreneau RJ, Siegfried JM, Yu J, Zhang L. Downregulation of Dkk3 activates beta-catenin/TCF-4 signaling in lung cancer. Carcinogenesis. 2008; 29:84-92.
-
(2008)
Carcinogenesis
, vol.29
, pp. 84-92
-
-
Yue, W.1
Sun, Q.2
Dacic, S.3
Landreneau, R.J.4
Siegfried, J.M.5
Yu, J.6
Zhang, L.7
-
11
-
-
68049133175
-
Fibulin-5 suppresses lung cancer invasion by inhibiting matrix metalloproteinase-7 expression
-
Yue W, Sun Q, Landreneau R, Wu C, Siegfried JM, Yu J, Zhang L. Fibulin-5 suppresses lung cancer invasion by inhibiting matrix metalloproteinase-7 expression. Cancer Res. 2009; 69:6339-6346.
-
(2009)
Cancer Res
, vol.69
, pp. 6339-6346
-
-
Yue, W.1
Sun, Q.2
Landreneau, R.3
Wu, C.4
Siegfried, J.M.5
Yu, J.6
Zhang, L.7
-
12
-
-
84905705835
-
Fibulin-3 suppresses Wnt/beta-catenin signaling and lung cancer invasion
-
Chen X, Meng J, Yue W, Yu J, Yang J, Yao Z, Zhang L. Fibulin-3 suppresses Wnt/beta-catenin signaling and lung cancer invasion. Carcinogenesis. 2014; 35:1707-1716.
-
(2014)
Carcinogenesis
, vol.35
, pp. 1707-1716
-
-
Chen, X.1
Meng, J.2
Yue, W.3
Yu, J.4
Yang, J.5
Yao, Z.6
Zhang, L.7
-
13
-
-
0036516460
-
Matrix metalloproteinases: a tail of a frog that became a prince
-
Brinckerhoff CE, Matrisian LM. Matrix metalloproteinases: a tail of a frog that became a prince. Nat Rev Mol Cell Biol. 2002; 3:207-214.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 207-214
-
-
Brinckerhoff, C.E.1
Matrisian, L.M.2
-
14
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nat Med. 2004; 10:789-799.
-
(2004)
Nat Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
15
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H. Wnt/beta-catenin signaling in development and disease. Cell. 2006; 127:469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
16
-
-
85047696569
-
gamma-Catenin expression is reduced or absent in a subset of human lung cancers and re-expression inhibits transformed cell growth
-
Winn RA, Bremnes RM, Bemis L, Franklin WA, Miller YE, Cool C, Heasley LE. gamma-Catenin expression is reduced or absent in a subset of human lung cancers and re-expression inhibits transformed cell growth. Oncogene. 2002; 21:7497-7506.
-
(2002)
Oncogene
, vol.21
, pp. 7497-7506
-
-
Winn, R.A.1
Bremnes, R.M.2
Bemis, L.3
Franklin, W.A.4
Miller, Y.E.5
Cool, C.6
Heasley, L.E.7
-
17
-
-
33845293454
-
Human arrest defective 1 acetylates and activates beta-catenin, promoting lung cancer cell proliferation
-
Lim JH, Park JW, Chun YS. Human arrest defective 1 acetylates and activates beta-catenin, promoting lung cancer cell proliferation. Cancer Res. 2006; 66:10677-10682.
-
(2006)
Cancer Res
, vol.66
, pp. 10677-10682
-
-
Lim, J.H.1
Park, J.W.2
Chun, Y.S.3
-
18
-
-
4344570800
-
Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells
-
You L, He B, Xu Z, Uematsu K, Mazieres J, Mikami I, Reguart N, Moody TW, Kitajewski J, McCormick F, Jablons DM. Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells. Oncogene. 2004; 23:6170-6174.
-
(2004)
Oncogene
, vol.23
, pp. 6170-6174
-
-
You, L.1
He, B.2
Xu, Z.3
Uematsu, K.4
Mazieres, J.5
Mikami, I.6
Reguart, N.7
Moody, T.W.8
Kitajewski, J.9
McCormick, F.10
Jablons, D.M.11
-
19
-
-
67649662201
-
WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis
-
Nguyen DX, Chiang AC, Zhang XH, Kim JY, Kris MG, Ladanyi M, Gerald WL, Massague J. WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis. Cell. 2009; 138:51-62.
-
(2009)
Cell
, vol.138
, pp. 51-62
-
-
Nguyen, D.X.1
Chiang, A.C.2
Zhang, X.H.3
Kim, J.Y.4
Kris, M.G.5
Ladanyi, M.6
Gerald, W.L.7
Massague, J.8
-
20
-
-
84908364943
-
Wnt signaling pathway: implications for therapy in lung cancer and bone metastasis
-
Xi Y, Chen Y. Wnt signaling pathway: implications for therapy in lung cancer and bone metastasis. Cancer Lett. 2014; 353:8-16.
-
(2014)
Cancer Lett
, vol.353
, pp. 8-16
-
-
Xi, Y.1
Chen, Y.2
-
21
-
-
0033529126
-
The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors
-
Crawford HC, Fingleton BM, Rudolph-Owen LA, Goss KJ, Rubinfeld B, Polakis P, Matrisian LM. The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors. Oncogene. 1999; 18:2883-2891.
-
(1999)
Oncogene
, vol.18
, pp. 2883-2891
-
-
Crawford, H.C.1
Fingleton, B.M.2
Rudolph-Owen, L.A.3
Goss, K.J.4
Rubinfeld, B.5
Polakis, P.6
Matrisian, L.M.7
-
22
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, Morin PJ, Vogelstein B, Kinzler KW. Identification of c-MYC as a target of the APC pathway. Science. 1998; 281:1509-1512.
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
Hermeking, H.4
Zawel, L.5
da Costa, L.T.6
Morin, P.J.7
Vogelstein, B.8
Kinzler, K.W.9
-
23
-
-
0033119801
-
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
-
Tetsu O, McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature. 1999; 398:422-426.
-
(1999)
Nature
, vol.398
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
24
-
-
22544433759
-
Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin
-
Ding Q, Xia W, Liu JC, Yang JY, Lee DF, Xia J, Bartholomeusz G, Li Y, Pan Y, Li Z, Bargou RC, Qin J, Lai CC, Tsai FJ, Tsai CH, Hung MC. Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin. Mol Cell. 2005; 19:159-170.
-
(2005)
Mol Cell
, vol.19
, pp. 159-170
-
-
Ding, Q.1
Xia, W.2
Liu, J.C.3
Yang, J.Y.4
Lee, D.F.5
Xia, J.6
Bartholomeusz, G.7
Li, Y.8
Pan, Y.9
Li, Z.10
Bargou, R.C.11
Qin, J.12
Lai, C.C.13
Tsai, F.J.14
Tsai, C.H.15
Hung, M.C.16
-
25
-
-
84885137302
-
Exploring TCGA Pan-Cancer Data at the UCSC Cancer Genomics Browser
-
Cline MS, Craft B, Swatloski T, Goldman M, Ma S, Haussler D, Zhu J. Exploring TCGA Pan-Cancer Data at the UCSC Cancer Genomics Browser. Scientific reports. 2013; 3:2652.
-
(2013)
Scientific reports
, vol.3
, pp. 2652
-
-
Cline, M.S.1
Craft, B.2
Swatloski, T.3
Goldman, M.4
Ma, S.5
Haussler, D.6
Zhu, J.7
-
26
-
-
84893181929
-
Online survival analysis software to assess the prognostic value of biomarkers using transcriptomic data in non-small-cell lung cancer
-
Gyorffy B, Surowiak P, Budczies J, Lanczky A. Online survival analysis software to assess the prognostic value of biomarkers using transcriptomic data in non-small-cell lung cancer. PLoS One. 2013; 8:e82241.
-
(2013)
PLoS One
, vol.8
-
-
Gyorffy, B.1
Surowiak, P.2
Budczies, J.3
Lanczky, A.4
-
27
-
-
34547673238
-
Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation
-
Yue W, Dacic S, Sun Q, Landreneau R, Guo M, Zhou W, Siegfried JM, Yu J, Zhang L. Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation. Clin Cancer Res. 2007; 13:4336-4344.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4336-4344
-
-
Yue, W.1
Dacic, S.2
Sun, Q.3
Landreneau, R.4
Guo, M.5
Zhou, W.6
Siegfried, J.M.7
Yu, J.8
Zhang, L.9
-
28
-
-
84908012088
-
TAp73 promotes cell survival upon genotoxic stress by inhibiting p53 activity
-
Chen D, Ming L, Zou F, Peng Y, Van Houten B, Yu J, Zhang L. TAp73 promotes cell survival upon genotoxic stress by inhibiting p53 activity. Oncotarget. 2014; 5:8107-8122.
-
(2014)
Oncotarget
, vol.5
, pp. 8107-8122
-
-
Chen, D.1
Ming, L.2
Zou, F.3
Peng, Y.4
Van Houten, B.5
Yu, J.6
Zhang, L.7
-
29
-
-
34547788854
-
Expression of mRNA MMP-7 and mRNA TIMP-1 in non-small cell lung cancer
-
Safranek J, Holubec L Jr, Topolcan O, Pesta M, Klecka J, Vodicka J, Finek J, Kormunda S, Pesek M. Expression of mRNA MMP-7 and mRNA TIMP-1 in non-small cell lung cancer. Anticancer Res. 2007; 27:2953-2956.
-
(2007)
Anticancer Res
, vol.27
, pp. 2953-2956
-
-
Safranek, J.1
Holubec, L.2
Topolcan, O.3
Pesta, M.4
Klecka, J.5
Vodicka, J.6
Finek, J.7
Kormunda, S.8
Pesek, M.9
-
30
-
-
16644397431
-
Expression spectra of matrix metalloproteinases in metastatic non-small cell lung cancer
-
Lin TS, Chiou SH, Wang LS, Huang HH, Chiang SF, Shih AY, Chen YL, Chen CY, Hsu CP, Hsu NY, Chou MC, Kuo SJ, Chow KC. Expression spectra of matrix metalloproteinases in metastatic non-small cell lung cancer. Oncol Rep. 2004; 12:717-723.
-
(2004)
Oncol Rep
, vol.12
, pp. 717-723
-
-
Lin, T.S.1
Chiou, S.H.2
Wang, L.S.3
Huang, H.H.4
Chiang, S.F.5
Shih, A.Y.6
Chen, Y.L.7
Chen, C.Y.8
Hsu, C.P.9
Hsu, N.Y.10
Chou, M.C.11
Kuo, S.J.12
Chow, K.C.13
-
31
-
-
33645047392
-
Fibulins 3 and 5 antagonize tumor angiogenesis in vivo
-
Albig AR, Neil JR, Schiemann WP. Fibulins 3 and 5 antagonize tumor angiogenesis in vivo. Cancer Res. 2006; 66:2621-2629.
-
(2006)
Cancer Res
, vol.66
, pp. 2621-2629
-
-
Albig, A.R.1
Neil, J.R.2
Schiemann, W.P.3
-
32
-
-
79956024181
-
Role of fibulin-5 in metastatic organ colonization
-
Moller HD, Ralfkjaer U, Cremers N, Frankel M, Pedersen RT, Klingelhofer J, Yanagisawa H, Grigorian M, Guldberg P, Sleeman J, Lukanidin E, Ambartsumian N. Role of fibulin-5 in metastatic organ colonization. Mol Cancer Res. 2011; 9:553-563.
-
(2011)
Mol Cancer Res
, vol.9
, pp. 553-563
-
-
Moller, H.D.1
Ralfkjaer, U.2
Cremers, N.3
Frankel, M.4
Pedersen, R.T.5
Klingelhofer, J.6
Yanagisawa, H.7
Grigorian, M.8
Guldberg, P.9
Sleeman, J.10
Lukanidin, E.11
Ambartsumian, N.12
-
33
-
-
84893564877
-
Oncogenic fibulin-5 promotes nasopharyngeal carcinoma cell metastasis through the FLJ10540/AKT pathway and correlates with poor prognosis
-
Hwang CF, Shiu LY, Su LJ, Yu-Fang Y, Wang WS, Huang SC, Chiu TJ, Huang CC, Zhen YY, Tsai HT, Fang FM, Huang TL, Chen CH. Oncogenic fibulin-5 promotes nasopharyngeal carcinoma cell metastasis through the FLJ10540/AKT pathway and correlates with poor prognosis. PLoS One. 2013; 8:e84218.
-
(2013)
PLoS One
, vol.8
-
-
Hwang, C.F.1
Shiu, L.Y.2
Su, L.J.3
Yu-Fang, Y.4
Wang, W.S.5
Huang, S.C.6
Chiu, T.J.7
Huang, C.C.8
Zhen, Y.Y.9
Tsai, H.T.10
Fang, F.M.11
Huang, T.L.12
Chen, C.H.13
-
34
-
-
57349137178
-
Fibulin-5 initiates epithelial-mesenchymal transition (EMT) and enhances EMT induced by TGFbeta in mammary epithelial cells via a MMP-dependent mechanism
-
Lee YH, Albig AR, Regner M, Schiemann BJ, Schiemann WP. Fibulin-5 initiates epithelial-mesenchymal transition (EMT) and enhances EMT induced by TGFbeta in mammary epithelial cells via a MMP-dependent mechanism. Carcinogenesis. 2008; 29:2243-2251.
-
(2008)
Carcinogenesis
, vol.29
, pp. 2243-2251
-
-
Lee, Y.H.1
Albig, A.R.2
Regner, M.3
Schiemann, B.J.4
Schiemann, W.P.5
-
35
-
-
0142150945
-
Coordinate expression of fibulin-5/DANCE and elastin during lung injury repair
-
Kuang PP, Goldstein RH, Liu Y, Rishikof DC, Jean JC, Joyce-Brady M. Coordinate expression of fibulin-5/DANCE and elastin during lung injury repair. Am J Physiol Lung Cell Mol Physiol. 2003; 285:L1147-1152.
-
(2003)
Am J Physiol Lung Cell Mol Physiol
, vol.285
, pp. L1147-L1152
-
-
Kuang, P.P.1
Goldstein, R.H.2
Liu, Y.3
Rishikof, D.C.4
Jean, J.C.5
Joyce-Brady, M.6
-
36
-
-
25444527720
-
Increased fibulin-5 and elastin in S100A4/Mts1 mice with pulmonary hypertension
-
Merklinger SL, Wagner RA, Spiekerkoetter E, Hinek A, Knutsen RH, Kabir MG, Desai K, Hacker S, Wang L, Cann GM, Ambartsumian NS, Lukanidin E, Bernstein D, Husain M, Mecham RP, Starcher B, Yanagisawa H, Rabinovitch M. Increased fibulin-5 and elastin in S100A4/Mts1 mice with pulmonary hypertension. Circ Res. 2005; 97:596-604.
-
(2005)
Circ Res
, vol.97
, pp. 596-604
-
-
Merklinger, S.L.1
Wagner, R.A.2
Spiekerkoetter, E.3
Hinek, A.4
Knutsen, R.H.5
Kabir, M.G.6
Desai, K.7
Hacker, S.8
Wang, L.9
Cann, G.M.10
Ambartsumian, N.S.11
Lukanidin, E.12
Bernstein, D.13
Husain, M.14
Mecham, R.P.15
Starcher, B.16
Yanagisawa, H.17
Rabinovitch, M.18
-
37
-
-
0037049996
-
Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo
-
Yanagisawa H, Davis EC, Starcher BC, Ouchi T, Yanagisawa M, Richardson JA, Olson EN. Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo. Nature. 2002; 415:168-171.
-
(2002)
Nature
, vol.415
, pp. 168-171
-
-
Yanagisawa, H.1
Davis, E.C.2
Starcher, B.C.3
Ouchi, T.4
Yanagisawa, M.5
Richardson, J.A.6
Olson, E.N.7
-
38
-
-
40849083445
-
Wnt signaling pathway and lung disease
-
Van Scoyk M, Randall J, Sergew A, Williams LM, Tennis M, Winn RA. Wnt signaling pathway and lung disease. Translational research: the journal of laboratory and clinical medicine. 2008; 151:175-180.
-
(2008)
Translational research: the journal of laboratory and clinical medicine
, vol.151
, pp. 175-180
-
-
Van Scoyk, M.1
Randall, J.2
Sergew, A.3
Williams, L.M.4
Tennis, M.5
Winn, R.A.6
-
40
-
-
67650320997
-
MYC is a metastasis gene for non-small-cell lung cancer
-
Rapp UR, Korn C, Ceteci F, Karreman C, Luetkenhaus K, Serafin V, Zanucco E, Castro I, Potapenko T. MYC is a metastasis gene for non-small-cell lung cancer. PLoS One. 2009; 4:e6029.
-
(2009)
PLoS One
, vol.4
-
-
Rapp, U.R.1
Korn, C.2
Ceteci, F.3
Karreman, C.4
Luetkenhaus, K.5
Serafin, V.6
Zanucco, E.7
Castro, I.8
Potapenko, T.9
-
41
-
-
80052836720
-
Activation of the Wnt/beta-catenin signaling pathway by mechanical ventilation is associated with ventilator-induced pulmonary fibrosis in healthy lungs
-
Villar J, Cabrera NE, Valladares F, Casula M, Flores C, Blanch L, Quilez ME, Santana-Rodriguez N, Kacmarek RM, Slutsky AS. Activation of the Wnt/beta-catenin signaling pathway by mechanical ventilation is associated with ventilator-induced pulmonary fibrosis in healthy lungs. PLoS One. 2011; 6:e23914.
-
(2011)
PLoS One
, vol.6
-
-
Villar, J.1
Cabrera, N.E.2
Valladares, F.3
Casula, M.4
Flores, C.5
Blanch, L.6
Quilez, M.E.7
Santana-Rodriguez, N.8
Kacmarek, R.M.9
Slutsky, A.S.10
-
42
-
-
0036488589
-
Role of integrins in cell invasion and migration
-
Hood JD, Cheresh DA. Role of integrins in cell invasion and migration. Nat Rev Cancer. 2002; 2:91-100.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 91-100
-
-
Hood, J.D.1
Cheresh, D.A.2
-
43
-
-
84907501988
-
Signaling mechanisms of the epithelial-mesenchymal transition
-
Gonzalez DM, Medici D. Signaling mechanisms of the epithelial-mesenchymal transition. Science signaling. 2014; 7:re8.
-
(2014)
Science signaling
, vol.7
-
-
Gonzalez, D.M.1
Medici, D.2
|