-
1
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
18772396 10.1126/science.1164382 1:CAS:528:DC%2BD1cXhtFCrtLrE
-
DW Parsons S Jones X Zhang, et al. 2008 An integrated genomic analysis of human glioblastoma multiforme Science 321 1807 1812 18772396 10.1126/science.1164382 1:CAS:528:DC%2BD1cXhtFCrtLrE
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
-
2
-
-
56749156414
-
Analysis of the IDH1 codon 132 mutation in brain tumors
-
18985363 10.1007/s00401-008-0455-2 1:CAS:528:DC%2BD1cXhtlyhsbfN
-
J Balss J Meyer W Mueller, et al. 2008 Analysis of the IDH1 codon 132 mutation in brain tumors Acta Neuropathol 116 597 602 18985363 10.1007/s00401-008-0455-2 1:CAS:528:DC%2BD1cXhtlyhsbfN
-
(2008)
Acta Neuropathol
, vol.116
, pp. 597-602
-
-
Balss, J.1
Meyer, J.2
Mueller, W.3
-
3
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
19228619 10.1056/NEJMoa0808710 1:CAS:528:DC%2BD1MXitFWru7o%3D
-
H Yan DW Parsons G Jin, et al. 2009 IDH1 and IDH2 mutations in gliomas N Engl J Med 360 765 773 19228619 10.1056/NEJMoa0808710 1:CAS:528: DC%2BD1MXitFWru7o%3D
-
(2009)
N Engl J Med
, vol.360
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
-
4
-
-
69949114447
-
Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: A study of 1,010 diffuse gliomas
-
19554337 10.1007/s00401-009-0561-9
-
C Hartmann J Meyer J Balss, et al. 2009 Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas Acta Neuropathol 118 469 474 19554337 10.1007/s00401-009-0561-9
-
(2009)
Acta Neuropathol
, vol.118
, pp. 469-474
-
-
Hartmann, C.1
Meyer, J.2
Balss, J.3
-
5
-
-
70349653793
-
IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas
-
19755387 10.1158/1078-0432.CCR-09-0715 1:CAS:528:DC%2BD1MXhtF2ltbbL
-
S Nobusawa T Watanabe P Kleihues, et al. 2009 IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas Clin Cancer Res 15 6002 6007 19755387 10.1158/1078-0432.CCR-09-0715 1:CAS:528:DC%2BD1MXhtF2ltbbL
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6002-6007
-
-
Nobusawa, S.1
Watanabe, T.2
Kleihues, P.3
-
6
-
-
68349116524
-
IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas
-
19435942 10.1215/15228517-2009-025 1:CAS:528:DC%2BD1MXhtV2qur%2FF
-
K Ichimura DM Pearson S Kocialkowski, et al. 2009 IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas Neuro Oncol 11 341 347 19435942 10.1215/15228517-2009-025 1:CAS:528:DC%2BD1MXhtV2qur%2FF
-
(2009)
Neuro Oncol
, vol.11
, pp. 341-347
-
-
Ichimura, K.1
Pearson, D.M.2
Kocialkowski, S.3
-
7
-
-
65349150503
-
IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas
-
19246647 10.2353/ajpath.2009.080958 1:CAS:528:DC%2BD1MXksVOksLY%3D
-
T Watanabe S Nobusawa P Kleihues, et al. 2009 IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas Am J Pathol 174 1149 1153 19246647 10.2353/ajpath.2009.080958 1:CAS:528:DC%2BD1MXksVOksLY%3D
-
(2009)
Am J Pathol
, vol.174
, pp. 1149-1153
-
-
Watanabe, T.1
Nobusawa, S.2
Kleihues, P.3
-
8
-
-
73349109131
-
Diagnostic use of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed, paraffin-embedded glioma tissues
-
19915484 10.1097/NEN.0b013e3181c391be 1:CAS:528:DC%2BD1MXhsVOhtLvE
-
C Horbinski J Kofler LM Kelly, et al. 2009 Diagnostic use of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed, paraffin-embedded glioma tissues J Neuropathol Exp Neurol 68 1319 1325 19915484 10.1097/NEN.0b013e3181c391be 1:CAS:528:DC%2BD1MXhsVOhtLvE
-
(2009)
J Neuropathol Exp Neurol
, vol.68
, pp. 1319-1325
-
-
Horbinski, C.1
Kofler, J.2
Kelly, L.M.3
-
9
-
-
70349594347
-
Analysis of IDH1 and IDH2 mutations in Japanese glioma patients
-
19765000 10.1111/j.1349-7006.2009.01270.x 1:CAS:528:DC%2BD1MXht12qs7bP
-
Y Sonoda T Kumabe T Nakamura, et al. 2009 Analysis of IDH1 and IDH2 mutations in Japanese glioma patients Cancer Sci 100 1996 1998 19765000 10.1111/j.1349-7006.2009.01270.x 1:CAS:528:DC%2BD1MXht12qs7bP
-
(2009)
Cancer Sci
, vol.100
, pp. 1996-1998
-
-
Sonoda, Y.1
Kumabe, T.2
Nakamura, T.3
-
10
-
-
80052764895
-
High-throughput immunohistochemical profiling of primary brain tumors and non-neoplastic systemic organs with a specific antibody against the mutant isocitrate dehydrogenase 1 R132H protein
-
Ikota H, Nobusawa S, Tanaka Y et al (2011) High-throughput immunohistochemical profiling of primary brain tumors and non-neoplastic systemic organs with a specific antibody against the mutant isocitrate dehydrogenase 1 R132H protein. Brain Tumor Pathol 28:107-114
-
(2011)
Brain Tumor Pathol
, vol.28
, pp. 107-114
-
-
Ikota, H.1
Nobusawa, S.2
Tanaka, Y.3
-
11
-
-
58349111311
-
IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors
-
19117336 10.1002/humu.20937 1:CAS:528:DC%2BD1MXivFygs7g%3D
-
FE Bleeker S Lamba S Leenstra, et al. 2009 IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors Hum Mutat 30 7 11 19117336 10.1002/humu.20937 1:CAS:528: DC%2BD1MXivFygs7g%3D
-
(2009)
Hum Mutat
, vol.30
, pp. 7-11
-
-
Bleeker, F.E.1
Lamba, S.2
Leenstra, S.3
-
12
-
-
78651110077
-
Isocitrate dehydrogenase 1/2 mutational analyses and 2-hydroxyglutarate measurements in Wilms tumors
-
Rakheja D, Mitui M, Boriack RL, Deberardinis RJ (2010) Isocitrate dehydrogenase 1/2 mutational analyses and 2-hydroxyglutarate measurements in Wilms tumors. Pediatr Blood Cancer 56:379-383
-
(2010)
Pediatr Blood Cancer
, vol.56
, pp. 379-383
-
-
Rakheja, D.1
Mitui, M.2
Boriack, R.L.3
Deberardinis, R.J.4
-
13
-
-
67449099808
-
Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers
-
19378339 10.1002/ijc.24379 1:CAS:528:DC%2BD1MXms1amu70%3D
-
MR Kang MS Kim JE Oh, et al. 2009 Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers Int J Cancer 125 353 355 19378339 10.1002/ijc.24379 1:CAS:528:DC%2BD1MXms1amu70%3D
-
(2009)
Int J Cancer
, vol.125
, pp. 353-355
-
-
Kang, M.R.1
Kim, M.S.2
Oh, J.E.3
-
14
-
-
77956265489
-
IDH mutations in glioma and acute myeloid leukemia
-
20692206 10.1016/j.molmed.2010.07.002 1:CAS:528:DC%2BC3cXhtFajs7zJ
-
L Dang S Jin SM Su 2010 IDH mutations in glioma and acute myeloid leukemia Trends Mol Med 16 387 397 20692206 10.1016/j.molmed.2010.07.002 1:CAS:528:DC%2BC3cXhtFajs7zJ
-
(2010)
Trends Mol Med
, vol.16
, pp. 387-397
-
-
Dang, L.1
Jin, S.2
Su, S.M.3
-
15
-
-
78149466021
-
IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders
-
20946881 10.1016/j.bbrc.2010.10.038 1:CAS:528:DC%2BC3cXhsValtrzK
-
Y Zou Y Zeng DF Zhang SH Zou YF Cheng YG Yao 2010 IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders Biochem Biophys Res Commun 402 378 383 20946881 10.1016/j.bbrc.2010.10.038 1:CAS:528:DC%2BC3cXhsValtrzK
-
(2010)
Biochem Biophys Res Commun
, vol.402
, pp. 378-383
-
-
Zou, Y.1
Zeng, Y.2
Zhang, D.F.3
Zou, S.H.4
Cheng, Y.F.5
Yao, Y.G.6
-
16
-
-
68949126806
-
Mutations of IDH1 and IDH2 are not detected in brain metastases of colorectal cancer
-
19350208 10.1007/s11060-009-9855-y
-
M Holdhoff DW Parsons LA Diaz Jr 2009 Mutations of IDH1 and IDH2 are not detected in brain metastases of colorectal cancer J Neurooncol 94 297 19350208 10.1007/s11060-009-9855-y
-
(2009)
J Neurooncol
, vol.94
, pp. 297
-
-
Holdhoff, M.1
Parsons, D.W.2
Diaz Jr., L.A.3
-
17
-
-
78650018623
-
The next generation of glioma biomarkers: MGMT methylation, BRAF fusions and IDH1 mutations
-
10.1111/j.1750-3639.2010.00454.x
-
A von Deimling A Korshunov C Hartmann 2011 The next generation of glioma biomarkers: MGMT methylation, BRAF fusions and IDH1 mutations Brain Pathol 21 74 87 10.1111/j.1750-3639.2010.00454.x
-
(2011)
Brain Pathol
, vol.21
, pp. 74-87
-
-
Von Deimling, A.1
Korshunov, A.2
Hartmann, C.3
-
18
-
-
77149152775
-
Segregation of non-p.R132H mutations in IDH1 in distinct molecular subtypes of glioma
-
20077503 10.1002/humu.21201 1:CAS:528:DC%2BC3cXktVOns74%3D
-
LA Gravendeel NK Kloosterhof LB Bralten, et al. 2010 Segregation of non-p.R132H mutations in IDH1 in distinct molecular subtypes of glioma Hum Mutat 31 E1186 E1199 20077503 10.1002/humu.21201 1:CAS:528:DC%2BC3cXktVOns74%3D
-
(2010)
Hum Mutat
, vol.31
-
-
Gravendeel, L.A.1
Kloosterhof, N.K.2
Bralten, L.B.3
-
19
-
-
67349220062
-
Selective acquisition of IDH1 R132C mutations in astrocytomas associated with Li-Fraumeni syndrome
-
19340432 10.1007/s00401-009-0528-x 1:CAS:528:DC%2BD1MXlvFOksb8%3D
-
T Watanabe A Vital S Nobusawa, et al. 2009 Selective acquisition of IDH1 R132C mutations in astrocytomas associated with Li-Fraumeni syndrome Acta Neuropathol 117 653 656 19340432 10.1007/s00401-009-0528-x 1:CAS:528: DC%2BD1MXlvFOksb8%3D
-
(2009)
Acta Neuropathol
, vol.117
, pp. 653-656
-
-
Watanabe, T.1
Vital, A.2
Nobusawa, S.3
-
20
-
-
0022214781
-
1) to 2q33.3
-
DOI 10.1007/BF00295665
-
K Narahara S Kimura K Kikkawa, et al. 1985 Probable assignment of soluble isocitrate dehydrogenase (IDH1) to 2q33.3 Hum Genet 71 37 40 3861566 10.1007/BF00295665 1:CAS:528:DyaL28XhsFGh (Pubitemid 16252285)
-
(1985)
Human Genetics
, vol.71
, Issue.1
, pp. 37-40
-
-
Narahara, K.1
Kimura, S.2
Kikkawa, K.3
-
21
-
-
0019332922
-
Chemical characterization of distinct subunits of pig heart DPN-specific isocitrate dehydrogenase
-
7410398 1:CAS:528:DyaL3cXmtVSisr8%3D
-
N Ramachandran RF Colman 1980 Chemical characterization of distinct subunits of pig heart DPN-specific isocitrate dehydrogenase J Biol Chem 255 8859 8864 7410398 1:CAS:528:DyaL3cXmtVSisr8%3D
-
(1980)
J Biol Chem
, vol.255
, pp. 8859-8864
-
-
Ramachandran, N.1
Colman, R.F.2
-
22
-
-
52949086786
-
Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle
-
18806796 10.1038/ng.223 1:CAS:528:DC%2BD1cXhtFKht73K
-
DT Hartong M Dange TL McGee, et al. 2008 Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle Nat Genet 40 1230 1234 18806796 10.1038/ng.223 1:CAS:528:DC%2BD1cXhtFKht73K
-
(2008)
Nat Genet
, vol.40
, pp. 1230-1234
-
-
Hartong, D.T.1
Dange, M.2
McGee, T.L.3
-
23
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
19935646 10.1038/nature08617 1:CAS:528:DC%2BD1MXhsVGlurzE
-
L Dang DW White S Gross, et al. 2009 Cancer-associated IDH1 mutations produce 2-hydroxyglutarate Nature 462 739 744 19935646 10.1038/nature08617 1:CAS:528:DC%2BD1MXhsVGlurzE
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
-
24
-
-
77649122144
-
IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: A report of the European Organization for Research and Treatment of Cancer Brain Tumor Group
-
20160062 10.1158/1078-0432.CCR-09-2902
-
MJ van den Bent HJ Dubbink Y Marie, et al. 2010 IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treatment of Cancer Brain Tumor Group Clin Cancer Res 16 1597 1604 20160062 10.1158/1078-0432.CCR-09-2902
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1597-1604
-
-
Van Den Bent, M.J.1
Dubbink, H.J.2
Marie, Y.3
-
25
-
-
77953351926
-
All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2
-
20427748 10.1212/WNL.0b013e3181e1cf3a
-
M Labussière A Idbaih XW Wang, et al. 2010 All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2 Neurology 74 1886 1890 20427748 10.1212/WNL.0b013e3181e1cf3a
-
(2010)
Neurology
, vol.74
, pp. 1886-1890
-
-
Labussière, M.1
Idbaih, A.2
Wang, X.W.3
-
26
-
-
73349103157
-
Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: A prospective translational study of the German Glioma Network
-
19805672 10.1200/JCO.2009.23.0805 1:CAS:528:DC%2BC3cXhtVWisbg%3D
-
M Weller J Felsberg C Hartmann, et al. 2009 Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network J Clin Oncol 27 5743 5750 19805672 10.1200/JCO.2009.23.0805 1:CAS:528: DC%2BC3cXhtVWisbg%3D
-
(2009)
J Clin Oncol
, vol.27
, pp. 5743-5750
-
-
Weller, M.1
Felsberg, J.2
Hartmann, C.3
-
27
-
-
70249097408
-
Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas
-
19636000 10.1200/JCO.2009.21.9832 1:CAS:528:DC%2BD1MXhtF2jtLrP
-
M Sanson Y Marie S Paris, et al. 2009 Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas J Clin Oncol 27 4150 4154 19636000 10.1200/JCO.2009.21.9832 1:CAS:528:DC%2BD1MXhtF2jtLrP
-
(2009)
J Clin Oncol
, vol.27
, pp. 4150-4154
-
-
Sanson, M.1
Marie, Y.2
Paris, S.3
-
28
-
-
78650749129
-
Molecular signatures classify astrocytic gliomas by IDH1 mutation status
-
Toedt G, Barbus S, Wolter M et al (2010) Molecular signatures classify astrocytic gliomas by IDH1 mutation status. Int J Cancer 128:1095-1103
-
(2010)
Int J Cancer
, vol.128
, pp. 1095-1103
-
-
Toedt, G.1
Barbus, S.2
Wolter, M.3
-
29
-
-
73349108806
-
IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide
-
19933982 10.1212/WNL.0b013e3181c34ace 1:CAS:528:DC%2BD1MXhsVaks77K
-
HJ Dubbink W Taal R van Marion, et al. 2009 IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide Neurology 73 1792 1795 19933982 10.1212/WNL.0b013e3181c34ace 1:CAS:528:DC%2BD1MXhsVaks77K
-
(2009)
Neurology
, vol.73
, pp. 1792-1795
-
-
Dubbink, H.J.1
Taal, W.2
Van Marion, R.3
-
30
-
-
78149249554
-
IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas
-
20975057 10.1212/WNL.0b013e3181f96282 1:CAS:528:DC%2BC3cXhtlGmtrjK
-
C Houillier X Wang G Kaloshi, et al. 2010 IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas Neurology 75 1560 1566 20975057 10.1212/WNL.0b013e3181f96282 1:CAS:528:DC%2BC3cXhtlGmtrjK
-
(2010)
Neurology
, vol.75
, pp. 1560-1566
-
-
Houillier, C.1
Wang, X.2
Kaloshi, G.3
-
31
-
-
70449518400
-
Monoclonal antibody specific for IDH1 R132H mutation
-
19798509 10.1007/s00401-009-0595-z 1:CAS:528:DC%2BD1MXhtlKitLrK
-
D Capper H Zentgraf J Balss, et al. 2009 Monoclonal antibody specific for IDH1 R132H mutation Acta Neuropathol 118 599 601 19798509 10.1007/s00401-009- 0595-z 1:CAS:528:DC%2BD1MXhtlKitLrK
-
(2009)
Acta Neuropathol
, vol.118
, pp. 599-601
-
-
Capper, D.1
Zentgraf, H.2
Balss, J.3
-
32
-
-
68349088073
-
Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma
-
19543740 10.1007/s00401-009-0550-z 1:CAS:528:DC%2BD1MXptVGjt7c%3D
-
A Korshunov J Meyer D Capper, et al. 2009 Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma Acta Neuropathol 118 401 405 19543740 10.1007/s00401-009-0550-z 1:CAS:528: DC%2BD1MXptVGjt7c%3D
-
(2009)
Acta Neuropathol
, vol.118
, pp. 401-405
-
-
Korshunov, A.1
Meyer, J.2
Capper, D.3
-
33
-
-
71549122009
-
Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors
-
19903171 10.1111/j.1750-3639.2009.00352.x 1:CAS:528: DC%2BC3cXpvFOlsA%3D%3D
-
D Capper S Weissert J Balss, et al. 2010 Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors Brain Pathol 20 245 254 19903171 10.1111/j.1750-3639.2009.00352.x 1:CAS:528:DC%2BC3cXpvFOlsA%3D%3D
-
(2010)
Brain Pathol
, vol.20
, pp. 245-254
-
-
Capper, D.1
Weissert, S.2
Balss, J.3
-
34
-
-
77955142776
-
Application of mutant IDH1 antibody to differentiate diffuse glioma from nonneoplastic central nervous system lesions and therapy-induced changes
-
20661018 10.1097/PAS.0b013e3181e7740d
-
D Capper F Sahm C Hartmann, et al. 2010 Application of mutant IDH1 antibody to differentiate diffuse glioma from nonneoplastic central nervous system lesions and therapy-induced changes Am J Surg Pathol 34 1199 1204 20661018 10.1097/PAS.0b013e3181e7740d
-
(2010)
Am J Surg Pathol
, vol.34
, pp. 1199-1204
-
-
Capper, D.1
Sahm, F.2
Hartmann, C.3
-
35
-
-
77953023663
-
Mutant IDH1-specific immunohistochemistry distinguishes diffuse astrocytoma from astrocytosis
-
20044756 10.1007/s00401-009-0632-y
-
S Camelo-Piragua M Jansen A Ganguly, et al. 2010 Mutant IDH1-specific immunohistochemistry distinguishes diffuse astrocytoma from astrocytosis Acta Neuropathol 119 509 511 20044756 10.1007/s00401-009-0632-y
-
(2010)
Acta Neuropathol
, vol.119
, pp. 509-511
-
-
Camelo-Piragua, S.1
Jansen, M.2
Ganguly, A.3
-
36
-
-
78650226575
-
Molecular classification of low-grade diffuse gliomas
-
21075857 10.2353/ajpath.2010.100680
-
YH Kim S Nobusawa M Mittelbronn, et al. 2010 Molecular classification of low-grade diffuse gliomas Am J Pathol 177 2708 2714 21075857 10.2353/ajpath.2010.100680
-
(2010)
Am J Pathol
, vol.177
, pp. 2708-2714
-
-
Kim, Y.H.1
Nobusawa, S.2
Mittelbronn, M.3
-
38
-
-
69549111318
-
MGMT promoter hypermethylation in a series of 104 glioblastomas
-
19656999 1:CAS:528:DC%2BD1MXhtVSjur7N
-
M Mellai V Caldera L Annovazzi, et al. 2009 MGMT promoter hypermethylation in a series of 104 glioblastomas Cancer Genomics Proteomics 6 219 227 19656999 1:CAS:528:DC%2BD1MXhtVSjur7N
-
(2009)
Cancer Genomics Proteomics
, vol.6
, pp. 219-227
-
-
Mellai, M.1
Caldera, V.2
Annovazzi, L.3
-
39
-
-
0033557903
-
Inactivation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
-
M Esteller SR Hamilton PC Burger, et al. 1999 Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia Cancer Res 59 793 797 10029064 1:CAS:528:DyaK1MXht1Sjurk%3D (Pubitemid 29086728)
-
(1999)
Cancer Research
, vol.59
, Issue.4
, pp. 793-797
-
-
Esteller, M.1
Hamilton, S.R.2
Burger, P.C.3
Baylin, S.B.4
Herman, J.G.5
-
40
-
-
37249021342
-
Combined 1p/19q loss in oligodendroglial tumors: Predictive or prognostic biomarker?
-
DOI 10.1158/1078-0432.CCR-07-0573
-
M Weller H Berger C Hartmann, et al. 2007 Combined 1p/19q loss in oligodendroglial tumors: predictive or prognostic biomarker? Clin Cancer Res 13 6933 6937 18056167 10.1158/1078-0432.CCR-07-0573 1:CAS:528:DC%2BD2sXhtlyit7fL (Pubitemid 350276872)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.23
, pp. 6933-6937
-
-
Weller, M.1
Berger, H.2
Hartmann, C.3
Schramm, J.4
Westphal, M.5
Simon, M.6
Goldbrunner, R.7
Krex, D.8
Steinbach, J.P.9
Ostertag, C.B.10
Loeffler, M.11
Pietsch, T.12
Von Deimling, A.13
-
41
-
-
78651463452
-
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases
-
21251613 10.1016/j.ccr.2010.12.014 1:CAS:528:DC%2BC3MXpvValsQ%3D%3D
-
W Xu H Yang Y Liu, et al. 2011 Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases Cancer Cell 19 17 30 21251613 10.1016/j.ccr.2010.12.014 1:CAS:528: DC%2BC3MXpvValsQ%3D%3D
-
(2011)
Cancer Cell
, vol.19
, pp. 17-30
-
-
Xu, W.1
Yang, H.2
Liu, Y.3
-
42
-
-
78650019179
-
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
-
21130701 10.1016/j.ccr.2010.11.015 1:CAS:528:DC%2BC3cXhsFGhsbvJ
-
ME Figueroa O Abdel-Wahab C Lu, et al. 2010 Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation Cancer Cell 18 553 567 21130701 10.1016/j.ccr.2010.11.015 1:CAS:528:DC%2BC3cXhsFGhsbvJ
-
(2010)
Cancer Cell
, vol.18
, pp. 553-567
-
-
Figueroa, M.E.1
Abdel-Wahab, O.2
Lu, C.3
-
43
-
-
78651082266
-
Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: Implications for classification of gliomas
-
21088844 10.1007/s00401-010-0781-z
-
C Hartmann B Hentschel W Wick, et al. 2010 Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas Acta Neuropathol 120 707 718 21088844 10.1007/s00401-010-0781-z
-
(2010)
Acta Neuropathol
, vol.120
, pp. 707-718
-
-
Hartmann, C.1
Hentschel, B.2
Wick, W.3
-
44
-
-
78651067051
-
Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis
-
21080178 10.1007/s00401-010-0777-8
-
P Metellus B Coulibaly C Colin, et al. 2010 Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis Acta Neuropathol 120 719 729 21080178 10.1007/s00401-010-0777- 8
-
(2010)
Acta Neuropathol
, vol.120
, pp. 719-729
-
-
Metellus, P.1
Coulibaly, B.2
Colin, C.3
-
45
-
-
0031951532
-
Cyclin D1 expression in gliomas
-
DOI 10.1007/s004010050776
-
P Cavalla A Dutto R Piva, et al. 1998 Cyclin D1 expression in gliomas Acta Neuropathol 95 131 135 9498046 10.1007/s004010050776 1:CAS:528: DyaK1cXjslyhsQ%3D%3D (Pubitemid 28076006)
-
(1998)
Acta Neuropathologica
, vol.95
, Issue.2
, pp. 131-135
-
-
Cavalla, P.1
Dutto, A.2
Piva, R.3
Richiardi, P.4
Grosso, R.5
Schiffer, D.6
-
46
-
-
0034773936
-
Cyclin D1 expression in normal oligodendroglia and microglia cells: Its use in the differential diagnosis of oligodendrogliomas
-
DOI 10.1046/j.1440-1789.2001.00389.x
-
I Bosone P Cavalla L Chiadò-Piat, et al. 2001 Cyclin D1 expression in normal oligodendroglia and microglia cells: its use in the differential diagnosis of oligodendrogliomas Neuropathology 21 155 161 11666011 10.1046/j.1440-1789.2001.00389.x 1:STN:280:DC%2BD3MrmsVWnsQ%3D%3D (Pubitemid 32947277)
-
(2001)
Neuropathology
, vol.21
, Issue.3
, pp. 155-161
-
-
Bosone, I.1
Cavalla, P.2
Chiado-Piat, L.3
Vito, N.D.4
Schiffer, D.5
-
47
-
-
36348971065
-
Gliomagenesis and neural stem cells: Key role of hypoxia and concept of tumor 'neo-niche'
-
DOI 10.1016/j.mehy.2007.04.024, PII S0306987707003064
-
S Diabira X Morandi 2008 Gliomagenesis and neural stem cells: key role of hypoxia and concept of tumor 'neo-niche' Med Hypotheses 70 96 104 17614215 10.1016/j.mehy.2007.04.024 1:CAS:528:DC%2BD2sXhsVSrsbfL (Pubitemid 350161161)
-
(2008)
Medical Hypotheses
, vol.70
, Issue.1
, pp. 96-104
-
-
Diabira, S.1
Morandi, X.2
|