Inhibitory effect of pironetin analogue/colchicine hybrids on the expression of the VEGF, hTERT and c-Myc genes

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 16, 2015, Pages 3194-3198

  Vilanova, Concepción ^a   Díaz Oltra, Santiago ^a   Murga, Juan ^a   Falomir, Eva ^a   Carda, Miguel ^a   Marco, J Alberto ^b  

^a UNIVERSITAT JAUME I   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Antiangiogenesis; Colchicine; Hybrid molecules; Pironetin; Telomerase

Indexed keywords

ANTINEOPLASTIC AGENT; COLCHICINE DERIVATIVE; MYC PROTEIN; NATURAL PRODUCT; PIRONETIN DERIVATIVE; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG; VASCULOTROPIN; ANGIOGENESIS INHIBITOR; COLCHICINE; PIRONETIN; PYRONE DERIVATIVE; TELOMERASE; TERT PROTEIN, HUMAN; VASCULOTROPIN A;

ARTICLE; BIOLOGICAL ACTIVITY; CANCER INHIBITION; CARCINOGENESIS; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IC50; PROTEIN EXPRESSION; PROTEIN PROCESSING; QUANTITATIVE ANALYSIS; ANALOGS AND DERIVATIVES; BIOSYNTHESIS; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HT 29 CELL LINE; METABOLISM; ONCOGENE MYC; SYNTHESIS;

ANGIOGENESIS INHIBITORS; COLCHICINE; ENZYME ACTIVATION; GENE EXPRESSION; GENES, MYC; HT29 CELLS; HUMANS; PYRONES; TELOMERASE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84933567301     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.05.092     Document Type: Article

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