Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells

Genes and Development

Volumn 29, Issue 12, 2015, Pages 1239-1255

  Wamaitha, Sissy E ^a   del Valle, Ignacio ^a   Cho, Lily T Y ^a,d   Wei, Yingying ^b,e   Fogarty, Norah M E ^a   Blakeley, Paul ^a   Sherwood, Richard I ^c   Ji, Hongkai ^b   Niakan, Kathy K ^a  

^a THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^e CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Extraembryonic endoderm; Gata6; Human embryonic stem cells; Mouse embryonic stem cells; Pluripotency; Reprograming

Indexed keywords

FIBROBLAST GROWTH FACTOR 4; HEPATOCYTE NUCLEAR FACTOR 3GAMMA; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; KRUPPEL LIKE FACTOR 2; LAMININ; LIVER RECEPTOR HOMOLOG 1; NODAL SIGNALING PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; OSTEONECTIN; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 6; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX17; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTION FACTOR SOX7; FGF4 PROTEIN, MOUSE; GATA4 PROTEIN, MOUSE; GATA6 PROTEIN, MOUSE; POU5F1 PROTEIN, MOUSE; PROTEIN BINDING;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FATE; CELL RENEWAL; CHIMERA; CHROMATIN IMMUNOPRECIPITATION; DOWN REGULATION; EMBRYO; EMBRYONIC STEM CELL; ENDODERM; EXTRAEMBRYONIC ENDODERM STEM CELL; GENE ACTIVATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENE REPRESSION; GENETIC ASSOCIATION; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; MOUSE; NEURAL STEM CELL; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; BINDING SITE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ANIMALS; BINDING SITES; CELL DIFFERENTIATION; CELLULAR REPROGRAMMING; EMBRYONIC STEM CELLS; ENDODERM; FIBROBLAST GROWTH FACTOR 4; GATA4 TRANSCRIPTION FACTOR; GATA6 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE REGULATORY NETWORKS; HUMANS; MICE; OCTAMER TRANSCRIPTION FACTOR-3; PLURIPOTENT STEM CELLS; PROTEIN BINDING; SIGNAL TRANSDUCTION;

EID: 84933523732     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.257071.114     Document Type: Article

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