-
1
-
-
0032530342
-
Rituximab (anti-CD20 monoclonal antibody) for the treatment of patients with relapsing or refractory aggressive lymphoma: A multicenter phase II study
-
Coiffier B, Haioun C, Ketterer N, et al. Rituximab (anti-CD20 monoclonal antibody) for the treatment of patients with relapsing or refractory aggressive lymphoma: a multicenter phase II study. Blood. 1998;92:1927-1932.
-
(1998)
Blood
, vol.92
, pp. 1927-1932
-
-
Coiffier, B.1
Haioun, C.2
Ketterer, N.3
-
2
-
-
84872054301
-
CHOP and DHAP plus rituximab followed by autologous stem cell transplantation in mantle cell lymphoma: A phase 2 study from the Groupe d'Etude des Lymphomes de l'Adulte
-
Delarue R, Haioun C, Ribrag V, et al; Groupe d'Etude des Lymphomes de l'Adulte (GELA). CHOP and DHAP plus rituximab followed by autologous stem cell transplantation in mantle cell lymphoma: a phase 2 study from the Groupe d'Etude des Lymphomes de l'Adulte. Blood. 2013;121(1):48-53.
-
(2013)
Blood
, vol.121
, Issue.1
, pp. 48-53
-
-
Delarue, R.1
Haioun, C.2
Ribrag, V.3
-
3
-
-
8744274334
-
The addition of rituximab to a combination of fludarabine, cyclophosphamide, mitoxantrone (FCM) significantly increases the response rate and prolongs survival as compared with FCM alone in patients with relapsed and refractory follicular and mantle cell lymphomas: Results of a prospective randomized study of the German Low-Grade Lymphoma Study Group
-
Forstpointner R, Dreyling M, Repp R, et al; German Low-Grade Lymphoma Study Group. The addition of rituximab to a combination of fludarabine, cyclophosphamide, mitoxantrone (FCM) significantly increases the response rate and prolongs survival as compared with FCM alone in patients with relapsed and refractory follicular and mantle cell lymphomas: results of a prospective randomized study of the German Low-Grade Lymphoma Study Group. Blood. 2015;104(10):3064-3072.
-
(2015)
Blood
, vol.104
, Issue.10
, pp. 3064-3072
-
-
Forstpointner, R.1
Dreyling, M.2
Repp, R.3
-
4
-
-
33749545033
-
Rituximab maintenance improves clinical outcome of relapsed/resistant follicular non-Hodgkin lymphoma in patients both with and without rituximab during induction: Results of a prospective randomized phase 3 intergroup trial
-
van Oers MH, Klasa R, Marcus RE, et al. Rituximab maintenance improves clinical outcome of relapsed/resistant follicular non-Hodgkin lymphoma in patients both with and without rituximab during induction: results of a prospective randomized phase 3 intergroup trial. Baseline. 2006;108(10):3295-3301.
-
(2006)
Baseline
, vol.108
, Issue.10
, pp. 3295-3301
-
-
van Oers, M.H.1
Klasa, R.2
Marcus, R.E.3
-
5
-
-
28244439191
-
Long-term update of a phase II study of rituximab in combination with CHOP chemotherapy in patients with previously untreated, aggressive non-Hodgkin's lymphoma
-
Vose JM, Link BK, Grossbard ML, Czuczman M, Grillo-Lopez A, Fisher RI. Long-term update of a phase II study of rituximab in combination with CHOP chemotherapy in patients with previously untreated, aggressive non-Hodgkin's lymphoma. Leuk Lymphoma. 2005;46(11):1569-1573.
-
(2005)
Leuk Lymphoma
, vol.46
, Issue.11
, pp. 1569-1573
-
-
Vose, J.M.1
Link, B.K.2
Grossbard, M.L.3
Czuczman, M.4
Grillo-Lopez, A.5
Fisher, R.I.6
-
6
-
-
84907200622
-
Entering the era of targeted therapy for chronic lymphocytic leukemia: Impact on the practicing clinician
-
Byrd JC, Jones JJ, Woyach JA, Johnson AJ, Flynn JM. Entering the era of targeted therapy for chronic lymphocytic leukemia: impact on the practicing clinician. J Clin Oncol. 2014;32(27):3039-3047.
-
(2014)
J Clin Oncol
, vol.32
, Issue.27
, pp. 3039-3047
-
-
Byrd, J.C.1
Jones, J.J.2
Woyach, J.A.3
Johnson, A.J.4
Flynn, J.M.5
-
7
-
-
84933508838
-
19th Congress of the European Hematology Association, Milan, Italy, June 12-15, 2014
-
European Hematology Association. 19th Congress of the European Hematology Association, Milan, Italy, June 12-15, 2014. Haematologica. 2014;99(1 suppl):249.
-
(2014)
Haematologica
, vol.99
, Issue.1
, pp. 249
-
-
-
9
-
-
38049084406
-
Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase
-
Pan Z, Scheerens H, Li S-J, et al. Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase. Chem Med Chem. 2007;2(1): 58-61.
-
(2007)
Chem Med Chem
, vol.2
, Issue.1
, pp. 58-61
-
-
Pan, Z.1
Scheerens, H.2
Li, S.-J.3
-
10
-
-
61849183478
-
Bruton's tyrosine kinase (Btk): Function, regulation, and transformation with special emphasis on the PH domain
-
Mohamed A, Yu L, Backesjo C, Vargas L, Berglo A, Smith CIE. Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain. Immunol Rev. 2009;228:58-73.
-
(2009)
Immunol Rev
, vol.228
, pp. 58-73
-
-
Mohamed, A.1
Yu, L.2
Backesjo, C.3
Vargas, L.4
Berglo, A.5
Smith, C.I.E.6
-
11
-
-
84860433198
-
Bruton tyrosine kinase (BTK) and its role in B-cell malignancy
-
Buggy JJ. Bruton tyrosine kinase (BTK) and its role in B-cell malignancy. Int Rev Immunol. 2012;32(2):119-132.
-
(2012)
Int Rev Immunol
, vol.32
, Issue.2
, pp. 119-132
-
-
Buggy, J.J.1
-
12
-
-
84883556703
-
Bruton tyrosine kinase is commonly overexpressed in mantle cell lymphoma and its attenuation by ibrutinib induces apoptosis
-
Cinar M, Hamedani F, Mo Z, Cinar B, Amin HM, Alkan S. Bruton tyrosine kinase is commonly overexpressed in mantle cell lymphoma and its attenuation by ibrutinib induces apoptosis. Leuk Res. 2013;37(10):1271-1277.
-
(2013)
Leuk Res
, vol.37
, Issue.10
, pp. 1271-1277
-
-
Cinar, M.1
Hamedani, F.2
Mo, Z.3
Cinar, B.4
Amin, H.M.5
Alkan, S.6
-
13
-
-
73849145729
-
Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma
-
Davis RE, Ngo VN, Lenz G, et al. Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma. Nature. 2010;463(7277):88-92.
-
(2010)
Nature
, vol.463
, Issue.7277
, pp. 88-92
-
-
Davis, R.E.1
Ngo, V.N.2
Lenz, G.3
-
14
-
-
0000419304
-
Agammaglobulinemia
-
Bruton O. Agammaglobulinemia. Pediatrics. 1952;9:722-728.
-
(1952)
Pediatrics
, vol.9
, pp. 722-728
-
-
Bruton, O.1
-
16
-
-
0033945186
-
The role of Bruton's tyrosine kinase in B-cell development and function: A genetic perspective
-
Satterthwaite AB, Witte ON, Witte O. The role of Bruton's tyrosine kinase in B-cell development and function: a genetic perspective. Immunol Rev. 2000;6:120-127.
-
(2000)
Immunol Rev
, vol.6
, pp. 120-127
-
-
Satterthwaite, A.B.1
Witte, O.N.2
Witte, O.3
-
17
-
-
0035660786
-
Role of Bruton's tyrosine kinase in B cell development
-
Maas A, Hendriks RW. Role of Bruton's tyrosine kinase in B cell development. Dev Immunol. 2001;8:171-181.
-
(2001)
Dev Immunol
, vol.8
, pp. 171-181
-
-
Maas, A.1
Hendriks, R.W.2
-
18
-
-
84905842096
-
Bruton's tyrosine kinase: From X-linked agammaglobulinemia toward targeted therapy for B-cell malignancies
-
Ponader S, Burger JA. Bruton's tyrosine kinase: from X-linked agammaglobulinemia toward targeted therapy for B-cell malignancies. J Clin Oncol. 2014;32(17):1830-1839.
-
(2014)
J Clin Oncol
, vol.32
, Issue.17
, pp. 1830-1839
-
-
Ponader, S.1
Burger, J.A.2
-
19
-
-
84933535491
-
-
An improvement in survival or disease-related s
-
Indications and usage Imbruvica is indicated for the treatment of patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. This indication is based on overall response rate. An improvement in survival or disease-related s; 2013.
-
(2013)
This indication is based on overall response rate
-
-
MCL1
-
20
-
-
77955625479
-
The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy
-
Honigberg LA, Smith AM, Sirisawad M, et al. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy. Proc Natl Acad Sci U S A. 2010;107(29):13075-13080.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.29
, pp. 13075-13080
-
-
Honigberg, L.A.1
Smith, A.M.2
Sirisawad, M.3
-
21
-
-
84902343396
-
Breaking good: The inexorable rise of BTK inhibitors in the treatment of chronic lymphocytic leukaemia
-
Hutchinson CV, Dyer MJS. Breaking good: the inexorable rise of BTK inhibitors in the treatment of chronic lymphocytic leukaemia. Br J Haematol. 2014;166:12-22.
-
(2014)
Br J Haematol
, vol.166
, pp. 12-22
-
-
Hutchinson, C.V.1
Dyer, M.J.S.2
-
22
-
-
84885655403
-
Emerging drug profiles: Bruton's tyrosine kinase (BTK) inhibitor ibrutinib (PCI-32765)
-
Burger JA, Buggy JJ. Emerging drug profiles: Bruton's tyrosine kinase (BTK) inhibitor ibrutinib (PCI-32765). Leuk Lymphoma. 2013;54(11):2385-2391.
-
(2013)
Leuk Lymphoma
, vol.54
, Issue.11
, pp. 2385-2391
-
-
Burger, J.A.1
Buggy, J.J.2
-
23
-
-
84887695622
-
Egress of CD19(+) CD5(+) cells into peripheral blood following treatment with the Bruton tyrosine kinase inhibitor ibrutinib in mantle cell lymphoma patients
-
Chang BY, Francesco M, De Rooij MF, et al. Egress of CD19(+) CD5(+) cells into peripheral blood following treatment with the Bruton tyrosine kinase inhibitor ibrutinib in mantle cell lymphoma patients. Blood. 2013;122(14):2412-2424.
-
(2013)
Blood
, vol.122
, Issue.14
, pp. 2412-2424
-
-
Chang, B.Y.1
Francesco, M.2
De Rooij, M.F.3
-
24
-
-
84867589196
-
BTK inhibitor ibrutinib is cytotoxic to myeloma and potently enhances bortezomib and lenalidomide activities through NF-κB
-
Rushworth SA, Bowles KM, Barrera LN, Murray MY, Zaitseva L, MacEwan DJ. BTK inhibitor ibrutinib is cytotoxic to myeloma and potently enhances bortezomib and lenalidomide activities through NF-κB. Cell Signal. 2013;25:106-112.
-
(2013)
Cell Signal
, vol.25
, pp. 106-112
-
-
Rushworth, S.A.1
Bowles, K.M.2
Barrera, L.N.3
Murray, M.Y.4
Zaitseva, L.5
MacEwan, D.J.6
-
25
-
-
84901439281
-
Ibrutinib inhibits BCR and NF-κB signaling and reduces tumor proliferation in tissue-resident cells of patients with CLL
-
Herman SE, Mustafa RZ, Gyamfi JA, et al. Ibrutinib inhibits BCR and NF-κB signaling and reduces tumor proliferation in tissue-resident cells of patients with CLL. Blood. 2014;123(21):3286-3295.
-
(2014)
Blood
, vol.123
, Issue.21
, pp. 3286-3295
-
-
Herman, S.E.1
Mustafa, R.Z.2
Gyamfi, J.A.3
-
26
-
-
84899081280
-
Different sensitivity of germinal center B cell-like diffuse large B cell lymphoma cells towards ibrutinib treatment
-
Zheng X, Ding N, Song Y, Feng L, Zhu J. Different sensitivity of germinal center B cell-like diffuse large B cell lymphoma cells towards ibrutinib treatment. Cancer Cell Int. 2014;14(1):32.
-
(2014)
Cancer Cell Int
, vol.14
, Issue.1
, pp. 32
-
-
Zheng, X.1
Ding, N.2
Song, Y.3
Feng, L.4
Zhu, J.5
-
27
-
-
84871806385
-
Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765) has significant activity in patients with relapsed/refractory B-cell malignancies
-
Advani RH, Buggy JJ, Sharman JP, et al. Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765) has significant activity in patients with relapsed/refractory B-cell malignancies. J Clin Oncol. 2013;31(1):88-94.
-
(2013)
J Clin Oncol
, vol.31
, Issue.1
, pp. 88-94
-
-
Advani, R.H.1
Buggy, J.J.2
Sharman, J.P.3
-
29
-
-
30144443996
-
Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001
-
Morton LM, Wang SS, Devesa SS, Hartge P, Weisenburger DD, Linet MS. Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001. Blood. 2006;107(1):265-276.
-
(2006)
Blood
, vol.107
, Issue.1
, pp. 265-276
-
-
Morton, L.M.1
Wang, S.S.2
Devesa, S.S.3
Hartge, P.4
Weisenburger, D.D.5
Linet, M.S.6
-
30
-
-
75649140955
-
How I treat CLL up front
-
Gribben JG. How I treat CLL up front. Blood. 2010;115(2):187-197.
-
(2010)
Blood
, vol.115
, Issue.2
, pp. 187-197
-
-
Gribben, J.G.1
-
31
-
-
79952093131
-
Update on therapy of chronic lymphocytic leukemia
-
Gribben JG, O'Brien S. Update on therapy of chronic lymphocytic leukemia. J Clin Oncol. 2011;29(5):544-550.
-
(2011)
J Clin Oncol
, vol.29
, Issue.5
, pp. 544-550
-
-
Gribben, J.G.1
O'Brien, S.2
-
32
-
-
0028064764
-
A revised European-American classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group
-
Harris NL, Jaffe ES, Stein H, et al. A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood. 1994;84:1361-1392.
-
(1994)
Blood
, vol.84
, pp. 1361-1392
-
-
Harris, N.L.1
Jaffe, E.S.2
Stein, H.3
-
33
-
-
50249129796
-
Incidence trends of mantle cell lymphoma in the United States between 1992 and 2004
-
Zhou Y, Wang H, Fang W. Incidence trends of mantle cell lymphoma in the United States between 1992 and 2004. Cancer. 2008;113(4):791-798.
-
(2008)
Cancer
, vol.113
, Issue.4
, pp. 791-798
-
-
Zhou, Y.1
Wang, H.2
Fang, W.3
-
34
-
-
77954334194
-
Ten-year follow-up after intense chemoimmunotherapy with rituximab-hyperCVAD alternating with rituximab-high dose methotrexate/cytarabine (R-MA) and without stem cell transplantation in patients with untreated aggressive mantle cell lymphoma
-
Romaguera JE, Fayad LE, Feng L, et al. Ten-year follow-up after intense chemoimmunotherapy with rituximab-hyperCVAD alternating with rituximab-high dose methotrexate/cytarabine (R-MA) and without stem cell transplantation in patients with untreated aggressive mantle cell lymphoma. Br J Haematol. 2010;150(1995):200-208.
-
(2010)
Br J Haematol
, vol.150
, Issue.1995
, pp. 200-208
-
-
Romaguera, J.E.1
Fayad, L.E.2
Feng, L.3
-
35
-
-
84909944270
-
Current regimens and novel agents for mantle cell lymphoma
-
Chen Y, Wang M, Romaguera J. Current regimens and novel agents for mantle cell lymphoma. Br J Haematol. 2014;167(1):3-18.
-
(2014)
Br J Haematol
, vol.167
, Issue.1
, pp. 3-18
-
-
Chen, Y.1
Wang, M.2
Romaguera, J.3
-
36
-
-
78649792807
-
The role of the B-cell receptor in the pathogenesis of chronic lymphocytic leukaemia
-
Packham G, Stevenson F. The role of the B-cell receptor in the pathogenesis of chronic lymphocytic leukaemia. Semin Cancer Biol. 2010;20(6):391-399.
-
(2010)
Semin Cancer Biol
, vol.20
, Issue.6
, pp. 391-399
-
-
Packham, G.1
Stevenson, F.2
-
37
-
-
84858636448
-
The clinically active BTK inhibitor PCI-32765 targets B-cell receptor-and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia
-
de Rooij MF, Kuil A, Geest CR, et al. The clinically active BTK inhibitor PCI-32765 targets B-cell receptor-and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia. Blood. 2012;119:2590-2594.
-
(2012)
Blood
, vol.119
, pp. 2590-2594
-
-
de Rooij, M.F.1
Kuil, A.2
Geest, C.R.3
-
38
-
-
84863011553
-
The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo
-
Ponader S, Chen SS, Buggy JJ, et al. The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo. Blood. 2012;119:1182-1189.
-
(2012)
Blood
, vol.119
, pp. 1182-1189
-
-
Ponader, S.1
Chen, S.S.2
Buggy, J.J.3
-
39
-
-
84879748062
-
Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia
-
Byrd JC, Furman RR, Coutre SE, et al. Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia. N Engl J Med. 2013;369(1):32-42.
-
(2013)
N Engl J Med
, vol.369
, Issue.1
, pp. 32-42
-
-
Byrd, J.C.1
Furman, R.R.2
Coutre, S.E.3
-
40
-
-
84891373281
-
Ibrutinib as initial therapy for elderly patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma: An open-label, multicentre, phase 1b/2 trial
-
O'Brien S, Furman RR, Coutre SE, et al. Ibrutinib as initial therapy for elderly patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma: an open-label, multicentre, phase 1b/2 trial. Lancet Oncol. 2014;15(1):48-58.
-
(2014)
Lancet Oncol
, vol.15
, Issue.1
, pp. 48-58
-
-
O'Brien, S.1
Furman, R.R.2
Coutre, S.E.3
-
41
-
-
84921740802
-
Ibrutinib for previously untreated and relapsed or refractory chronic lymphocytic leukaemia with TP53 aberrations: A phase 2, single-arm trial
-
Farooqui MZ, Valdez J, Martyr S, et al. Ibrutinib for previously untreated and relapsed or refractory chronic lymphocytic leukaemia with TP53 aberrations: a phase 2, single-arm trial. Lancet Oncol. 2015;16(2):169-176.
-
(2015)
Lancet Oncol
, vol.16
, Issue.2
, pp. 169-176
-
-
Farooqui, M.Z.1
Valdez, J.2
Martyr, S.3
-
42
-
-
84904252369
-
Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia
-
Byrd JC, Brown JR, O'Brien S, et al; RESONATE Investigators. Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia. N Engl J Med. 2014;371(3):213-223.
-
(2014)
N Engl J Med
, vol.371
, Issue.3
, pp. 213-223
-
-
Byrd, J.C.1
Brown, J.R.2
O'Brien, S.3
RESONATE Investigators4
-
43
-
-
84906855910
-
Safety and activity of ibrutinib plus rituximab for patients with high-risk chronic lymphocytic leukaemia: A single-arm, phase 2 study
-
Burger JA, Keating MJ, Wierda WG, et al. Safety and activity of ibrutinib plus rituximab for patients with high-risk chronic lymphocytic leukaemia: a single-arm, phase 2 study. Lancet Oncol. 2014;15(10):1090-1099.
-
(2014)
Lancet Oncol
, vol.15
, Issue.10
, pp. 1090-1099
-
-
Burger, J.A.1
Keating, M.J.2
Wierda, W.G.3
-
45
-
-
84912122613
-
A phase 1b/2 study evaluating activity and tolerability of the BTK inhibitor ibrutinib in combination with ofatumumab in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and related diseases
-
abstr 7009
-
Jaglowski SM, Jones JA, Flynn JM, et al. A phase 1b/2 study evaluating activity and tolerability of the BTK inhibitor ibrutinib in combination with ofatumumab in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and related diseases. J Clin Oncol. 2014;32(suppl; abstr 7009):5s.
-
(2014)
J Clin Oncol
, vol.32
-
-
Jaglowski, S.M.1
Jones, J.A.2
Flynn, J.M.3
-
46
-
-
84894552888
-
Obinutuzumab plus chlorambucil in patients with CLL and coexisting conditions
-
Goede V, Fischer K, Busch R, et al. Obinutuzumab plus chlorambucil in patients with CLL and coexisting conditions. N Engl J Med. 2014;370:1101-1110.
-
(2014)
N Engl J Med
, vol.370
, pp. 1101-1110
-
-
Goede, V.1
Fischer, K.2
Busch, R.3
-
47
-
-
80053350801
-
Lenalidomide as initial therapy of elderly patients with chronic lymphocytic leukemia
-
Badoux XC, Keating MJ, Wen S, et al. Lenalidomide as initial therapy of elderly patients with chronic lymphocytic leukemia. Blood. 2015;118(13):3489-3499.
-
(2015)
Blood
, vol.118
, Issue.13
, pp. 3489-3499
-
-
Badoux, X.C.1
Keating, M.J.2
Wen, S.3
-
48
-
-
84881225049
-
Targeting BTK with ibrutinib in relapsed or refractory mantle-cell lymphoma
-
Wang ML, Rule S, Martin P, et al. Targeting BTK with ibrutinib in relapsed or refractory mantle-cell lymphoma. N Engl J Med. 2013;369(6):507-516.
-
(2013)
N Engl J Med
, vol.369
, Issue.6
, pp. 507-516
-
-
Wang, M.L.1
Rule, S.2
Martin, P.3
-
49
-
-
56049111424
-
Phase 2 trial of rituximab plus hyper-CVAD alternating with rituximab plus methotrexate-cytarabine for relapsed or refractory aggressive mantle cell lymphoma
-
Wang M, Fayad L, Cabanillas F. Phase 2 trial of rituximab plus hyper-CVAD alternating with rituximab plus methotrexate-cytarabine for relapsed or refractory aggressive mantle cell lymphoma. Cancer. 2008;113(10):2734-2741.
-
(2008)
Cancer
, vol.113
, Issue.10
, pp. 2734-2741
-
-
Wang, M.1
Fayad, L.2
Cabanillas, F.3
-
50
-
-
33750625445
-
Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma
-
Fisher RI, Bernstein SH, Kahl BS, et al. Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma. J Clin Oncol. 2006;24:4867-4874.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4867-4874
-
-
Fisher, R.I.1
Bernstein, S.H.2
Kahl, B.S.3
-
51
-
-
84920592861
-
Mantle cell lymphoma-evolving management strategies
-
Campo E, Rule S. Mantle cell lymphoma-evolving management strategies. Blood. 2015;125(1).
-
(2015)
Blood
, vol.125
, Issue.1
-
-
Campo, E.1
Rule, S.2
-
52
-
-
84933535493
-
Ibrutinib and rituximab are an efficacious and safe combination in relapsed mantle cell lymphoma: Preliminary results from a phase II clinical trial
-
Wang ML, Hagemeister F, Westin JR, et al. Ibrutinib and rituximab are an efficacious and safe combination in relapsed mantle cell lymphoma: preliminary results from a phase II clinical trial. J Clin Oncol. 2014.
-
(2014)
J Clin Oncol
-
-
Wang, M.L.1
Hagemeister, F.2
Westin, J.R.3
-
53
-
-
84918531430
-
Independent evaluation of ibrutinib efficacy 3 years post-initiation of monotherapy in patients with chronic lymphocytic leukemia/small lymphocytic leukemia including deletion 17p disease
-
O'Brien SM, Furman RR, Coutre SE, et al. Independent evaluation of ibrutinib efficacy 3 years post-initiation of monotherapy in patients with chronic lymphocytic leukemia/small lymphocytic leukemia including deletion 17p disease. ASCO Meet Abstr. 2014;32(15 suppl):7014.
-
(2014)
ASCO Meet Abstr
, vol.32
, Issue.15
, pp. 7014
-
-
O'Brien, S.M.1
Furman, R.R.2
Coutre, S.E.3
-
54
-
-
84904257213
-
Ibrutinib treatment of CLL: The cancer fights back
-
Young RM, Staudt LM. Ibrutinib treatment of CLL: the cancer fights back. Cancer Cell. 2014;26(1):11-13.
-
(2014)
Cancer Cell
, vol.26
, Issue.1
, pp. 11-13
-
-
Young, R.M.1
Staudt, L.M.2
-
55
-
-
84902183019
-
Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib
-
Woyach JA, Furman RR, Liu TM, et al. Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib. N Engl J Med. 2014;370:2286-2294.
-
(2014)
N Engl J Med
, vol.370
, pp. 2286-2294
-
-
Woyach, J.A.1
Furman, R.R.2
Liu, T.M.3
-
56
-
-
84933522569
-
XIII Congress of the Italian Society of Experimental Hematology Rimini, Italy, October 15-17, 2014
-
European Hematology Association. XIII Congress of the Italian Society of Experimental Hematology Rimini, Italy, October 15-17, 2014. Haematology. 2014;99(suppl 2):S1-S113.
-
(2014)
Haematology
, vol.99
, pp. S1-S113
-
-
-
57
-
-
84897069190
-
Prolonged lymphocytosis during ibrutinib therapy is associated with distinct molecular characteristics and does not indicate a suboptimal response to therapy
-
Woyach JA, Smucker K, Smith LL, et al. Prolonged lymphocytosis during ibrutinib therapy is associated with distinct molecular characteristics and does not indicate a suboptimal response to therapy. Blood. 2014;123:1810-1817.
-
(2014)
Blood
, vol.123
, pp. 1810-1817
-
-
Woyach, J.A.1
Smucker, K.2
Smith, L.L.3
-
58
-
-
84907312674
-
Characterization of ibrutinib-sensitive and-resistant mantle lymphoma cells
-
Ma J, Lu P, Guo A, et al. Characterization of ibrutinib-sensitive and-resistant mantle lymphoma cells. Br J Haematol. 2014;166(6):849-861.
-
(2014)
Br J Haematol
, vol.166
, Issue.6
, pp. 849-861
-
-
Ma, J.1
Lu, P.2
Guo, A.3
-
59
-
-
84864779051
-
Mesenchymal stromal cells protect mantle cell lymphoma cells from spontaneous and drug-induced apoptosis through secretion of B-cell activating factor and activation of the canonical and non-canonical nuclear factor κB pathways
-
Medina DJ, Goodell L, Glod J, Gélinas C, Rabson AB, Strair RK. Mesenchymal stromal cells protect mantle cell lymphoma cells from spontaneous and drug-induced apoptosis through secretion of B-cell activating factor and activation of the canonical and non-canonical nuclear factor κB pathways. Haematologica. 2012;97(8):1255-1263.
-
(2012)
Haematologica
, vol.97
, Issue.8
, pp. 1255-1263
-
-
Medina, D.J.1
Goodell, L.2
Glod, J.3
Gélinas, C.4
Rabson, A.B.5
Strair, R.K.6
-
60
-
-
84868567076
-
Role of the microenvironment in mantle cell lymphoma: IL-6 is an important survival factor for the tumor cells
-
Zhang L, Yang J, Qian J, et al. Role of the microenvironment in mantle cell lymphoma: IL-6 is an important survival factor for the tumor cells. Blood. 2012;120(18):3783-3792.
-
(2012)
Blood
, vol.120
, Issue.18
, pp. 3783-3792
-
-
Zhang, L.1
Yang, J.2
Qian, J.3
-
61
-
-
84899534929
-
Cobblestone-area forming cells derived from patients with mantle cell lymphoma are enriched for CD133+ tumor-initiating cells
-
Medina DJ, Abass-Shereef J, Walton K, et al. Cobblestone-area forming cells derived from patients with mantle cell lymphoma are enriched for CD133+ tumor-initiating cells. PLoS One. 2014;9(4):e91042.
-
(2014)
PLoS One
, vol.9
, Issue.4
-
-
Medina, D.J.1
Abass-Shereef, J.2
Walton, K.3
-
62
-
-
84933535494
-
Patients with mantle cell lymphoma failing ibrutinib are unlikely to respond to salvage chemotherapy and have poor outcomes
-
Cheah CY, Chihara D, Romaguera JE, et al. Patients with mantle cell lymphoma failing ibrutinib are unlikely to respond to salvage chemotherapy and have poor outcomes. Ann Oncol. 2015.
-
(2015)
Ann Oncol
-
-
Cheah, C.Y.1
Chihara, D.2
Romaguera, J.E.3
-
63
-
-
84907280381
-
Association of disease progression on ibrutinib therapy with the acquisition of resistance mutations: A single-center experience of 267 patients
-
Woyach JA, Ruppert AS, Lozanski G, et al. Association of disease progression on ibrutinib therapy with the acquisition of resistance mutations: a single-center experience of 267 patients. ASCO Meet Abstr. 2014;32(15 suppl):7010.
-
(2014)
ASCO Meet Abstr
, vol.32
, Issue.15
, pp. 7010
-
-
Woyach, J.A.1
Ruppert, A.S.2
Lozanski, G.3
-
64
-
-
84884523966
-
Ibrutinib in relapsed chronic lymphocytic leukemia
-
Byrd JC, O'Brien S, James DF. Ibrutinib in relapsed chronic lymphocytic leukemia. N Engl J Med. 2013;369:1278-1279.
-
(2013)
N Engl J Med
, vol.369
, pp. 1278-1279
-
-
Byrd, J.C.1
O'Brien, S.2
James, D.F.3
-
66
-
-
84896733911
-
Ibrutinib (PCI 32765) rapidly improves platelet counts in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) patients and has minimal effects on platelet aggregation
-
Abstract1789
-
Farooqui M, Lozier J, Valdez J, et al. Ibrutinib (PCI 32765) rapidly improves platelet counts in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) patients and has minimal effects on platelet aggregation. Blood. 2012;120:Abstract1789.
-
(2012)
Blood
, vol.120
-
-
Farooqui, M.1
Lozier, J.2
Valdez, J.3
-
67
-
-
84919494922
-
Ibrutinib treatment affects collagen and von Willebrand factor-dependent platelet functions
-
Levade M, David E, Garcia C, et al. Ibrutinib treatment affects collagen and von Willebrand factor-dependent platelet functions. Blood. 2015;124(26):3991-3996.
-
(2015)
Blood
, vol.124
, Issue.26
, pp. 3991-3996
-
-
Levade, M.1
David, E.2
Garcia, C.3
-
68
-
-
85027911790
-
Ibrutinib inhibits collagen-mediated but not ADP-mediated platelet aggregation
-
Kamel S, Horton L, Ysebaert L, et al. Ibrutinib inhibits collagen-mediated but not ADP-mediated platelet aggregation. Leukemia. 2014:1-5.
-
(2014)
Leukemia
, pp. 1-5
-
-
Kamel, S.1
Horton, L.2
Ysebaert, L.3
-
69
-
-
84933528655
-
Abstract 2432: The Bruton's tyrosine kinase inhibitor ibrutinib synergized with the proteasome inhibitor carfilzomib and overcame immunoproteasome-mediated carfilzomib resistance in mantle cell lymphoma
-
Ou Z, Zhang L, Newberry K, et al. Abstract 2432: the Bruton's tyrosine kinase inhibitor ibrutinib synergized with the proteasome inhibitor carfilzomib and overcame immunoproteasome-mediated carfilzomib resistance in mantle cell lymphoma. Cancer Res. 2013;73(8 suppl):2432.
-
(2013)
Cancer Res
, vol.73
, Issue.8
, pp. 2432
-
-
Ou, Z.1
Zhang, L.2
Newberry, K.3
-
70
-
-
84863107308
-
Lenalidomide in combination with rituximab for patients with relapsed or refractory mantle-cell lymphoma: A phase 1/2 clinical trial
-
Wang M, Fayad L, Wagner-Bartak N, et al. Lenalidomide in combination with rituximab for patients with relapsed or refractory mantle-cell lymphoma: a phase 1/2 clinical trial. Lancet Oncol. 2012;13(7):716-723.
-
(2012)
Lancet Oncol
, vol.13
, Issue.7
, pp. 716-723
-
-
Wang, M.1
Fayad, L.2
Wagner-Bartak, N.3
-
71
-
-
84889099537
-
Single-agent lenalidomide in patients with mantle-cell lymphoma who relapsed or progressed after or were refractory to bortezomib: Phase II MCL-001 (EMERGE) study
-
Goy A, Sinha R, Williams ME, et al. Single-agent lenalidomide in patients with mantle-cell lymphoma who relapsed or progressed after or were refractory to bortezomib: phase II MCL-001 (EMERGE) study. J Clin Oncol. 2013;31(29):3688-3695.
-
(2013)
J Clin Oncol
, vol.31
, Issue.29
, pp. 3688-3695
-
-
Goy, A.1
Sinha, R.2
Williams, M.E.3
-
72
-
-
84866875871
-
Single-agent lenalidomide in relapsed/refractory mantle cell lymphoma: Results from a UK phase II study suggest activity and possible gender differences
-
Eve HE, Carey S, Richardson SJ, et al. Single-agent lenalidomide in relapsed/refractory mantle cell lymphoma: results from a UK phase II study suggest activity and possible gender differences. Br J Haematol. 2012;159(2):154-163.
-
(2012)
Br J Haematol
, vol.159
, Issue.2
, pp. 154-163
-
-
Eve, H.E.1
Carey, S.2
Richardson, S.J.3
-
73
-
-
84896732823
-
Bruton's tyrosine kinase (BTK) inhibitors in clinical trials
-
Burger JA. Bruton's tyrosine kinase (BTK) inhibitors in clinical trials. Curr Hematol Malig Rep. 2014;9:44-49.
-
(2014)
Curr Hematol Malig Rep
, vol.9
, pp. 44-49
-
-
Burger, J.A.1
|