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Volumn 17, Issue 1, 2015, Pages

Transvenous vagus nerve stimulation does not modulate the innate immune response during experimental human endotoxemia: A randomized controlled study

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84933512859     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/s13075-015-0667-5     Document Type: Article
Times cited : (33)

References (50)
  • 1
    • 0035932519 scopus 로고    scopus 로고
    • Cytokine pathways and joint inflammation in rheumatoid arthritis
    • Choy EH, Panayi GS. Cytokine pathways and joint inflammation in rheumatoid arthritis. N Engl J Med. 2001;344:907-16.
    • (2001) N Engl J Med. , vol.344 , pp. 907-916
    • Choy, E.H.1    Panayi, G.S.2
  • 2
    • 79955040826 scopus 로고    scopus 로고
    • New therapies in the management of rheumatoid arthritis
    • Buch MH, Emery P. New therapies in the management of rheumatoid arthritis. Curr Opin Rheumatol. 2011;23:245-51.
    • (2011) Curr Opin Rheumatol. , vol.23 , pp. 245-251
    • Buch, M.H.1    Emery, P.2
  • 4
  • 5
    • 33747183943 scopus 로고    scopus 로고
    • Vagus nerve stimulation inhibits activation of coagulation and fibrinolysis during endotoxemia in rats
    • van Westerloo DJ, Giebelen IA, Meijers JC, Daalhuisen J, de Vos AF, Levi M, et al. Vagus nerve stimulation inhibits activation of coagulation and fibrinolysis during endotoxemia in rats. J Thromb Haemost. 2006;4:1997-2002.
    • (2006) J Thromb Haemost. , vol.4 , pp. 1997-2002
    • Westerloo, D.J.1    Giebelen, I.A.2    Meijers, J.C.3    Daalhuisen, J.4    Vos, A.F.5    Levi, M.6
  • 6
    • 36448948021 scopus 로고    scopus 로고
    • Transcutaneous vagus nerve stimulation reduces serum high mobility group box 1 levels and improves survival in murine sepsis
    • Huston JM, Gallowitsch-Puerta M, Ochani M, Ochani K, Yuan R, Rosas-Ballina M, et al. Transcutaneous vagus nerve stimulation reduces serum high mobility group box 1 levels and improves survival in murine sepsis. Crit Care Med. 2007;35:2762-8.
    • (2007) Crit Care Med. , vol.35 , pp. 2762-2768
    • Huston, J.M.1    Gallowitsch-Puerta, M.2    Ochani, M.3    Ochani, K.4    Yuan, R.5    Rosas-Ballina, M.6
  • 7
    • 84871998505 scopus 로고    scopus 로고
    • Parasympathetic stimulation via the vagus nerve prevents systemic organ dysfunction by abrogating gut injury and lymph toxicity in trauma and hemorrhagic shock
    • Levy G, Fishman JE, Xu D, Chandler BT, Feketova E, Dong W, et al. Parasympathetic stimulation via the vagus nerve prevents systemic organ dysfunction by abrogating gut injury and lymph toxicity in trauma and hemorrhagic shock. Shock. 2013;39:39-44.
    • (2013) Shock. , vol.39 , pp. 39-44
    • Levy, G.1    Fishman, J.E.2    Xu, D.3    Chandler, B.T.4    Feketova, E.5    Dong, W.6
  • 8
    • 0036998106 scopus 로고    scopus 로고
    • Cholinergic antiinflammatory pathway inhibition of tumor necrosis factor during ischemia reperfusion
    • Bernik TR, Friedman SG, Ochani M, DiRaimo R, Susarla S, Czura CJ, et al. Cholinergic antiinflammatory pathway inhibition of tumor necrosis factor during ischemia reperfusion. J Vasc Surg. 2002;36:1231-6.
    • (2002) J Vasc Surg. , vol.36 , pp. 1231-1236
    • Bernik, T.R.1    Friedman, S.G.2    Ochani, M.3    DiRaimo, R.4    Susarla, S.5    Czura, C.J.6
  • 9
    • 0037418233 scopus 로고    scopus 로고
    • Efferent vagal fibre stimulation blunts nuclear factor-kappaB activation and protects against hypovolemic hemorrhagic shock
    • Guarini S, Altavilla D, Cainazzo MM, Giuliani D, Bigiani A, Marini H, et al. Efferent vagal fibre stimulation blunts nuclear factor-kappaB activation and protects against hypovolemic hemorrhagic shock. Circulation. 2003;107:1189-94.
    • (2003) Circulation. , vol.107 , pp. 1189-1194
    • Guarini, S.1    Altavilla, D.2    Cainazzo, M.M.3    Giuliani, D.4    Bigiani, A.5    Marini, H.6
  • 10
    • 54049157816 scopus 로고    scopus 로고
    • The protective effect of the cholinergic anti-inflammatory pathway against septic shock in rats
    • Song XM, Li JG, Wang YL, Hu ZF, Zhou Q, Du ZH, et al. The protective effect of the cholinergic anti-inflammatory pathway against septic shock in rats. Shock. 2008;30:468-72.
    • (2008) Shock. , vol.30 , pp. 468-472
    • Song, X.M.1    Li, J.G.2    Wang, Y.L.3    Hu, Z.F.4    Zhou, Q.5    Du, Z.H.6
  • 11
    • 84905824890 scopus 로고    scopus 로고
    • Neurostimulation of the cholinergic anti-inflammatory pathway ameliorates disease in rat collagen-induced arthritis
    • Levine YA, Koopman FA, Faltys M, Caravaca A, Bendele A, Zitnik R, et al. Neurostimulation of the cholinergic anti-inflammatory pathway ameliorates disease in rat collagen-induced arthritis. PLoS One. 2014;9:e104530.
    • (2014) PLoS One. , vol.9 , pp. e104530
    • Levine, Y.A.1    Koopman, F.A.2    Faltys, M.3    Caravaca, A.4    Bendele, A.5    Zitnik, R.6
  • 12
    • 84921916845 scopus 로고    scopus 로고
    • Two novel alpha7 nicotinic acetylcholine receptor ligands: in vitro properties and their efficacy in collagen-induced arthritis in mice
    • van Maanen MA, Papke RL, Koopman FA, Koepke J, Bevaart L, Clark R, et al. Two novel alpha7 nicotinic acetylcholine receptor ligands: in vitro properties and their efficacy in collagen-induced arthritis in mice. PLoS One. 2015;10:e0116227.
    • (2015) PLoS One. , vol.10 , pp. e0116227
    • Maanen, M.A.1    Papke, R.L.2    Koopman, F.A.3    Koepke, J.4    Bevaart, L.5    Clark, R.6
  • 13
    • 58249121600 scopus 로고    scopus 로고
    • Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice
    • van Maanen MA, Lebre MC, van der Poll T, LaRosa GJ, Elbaum D, Vervoordeldonk MJ, et al. Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice. Arthritis Rheum. 2009;60:114-22.
    • (2009) Arthritis Rheum. , vol.60 , pp. 114-122
    • Maanen, M.A.1    Lebre, M.C.2    Poll, T.3    LaRosa, G.J.4    Elbaum, D.5    Vervoordeldonk, M.J.6
  • 14
    • 67650501700 scopus 로고    scopus 로고
    • The cholinergic anti-inflammatory pathway: towards innovative treatment of rheumatoid arthritis
    • van Maanen MA, Vervoordeldonk MJ, Tak PP. The cholinergic anti-inflammatory pathway: towards innovative treatment of rheumatoid arthritis. Nat Rev Rheumatol. 2009;5:229-32.
    • (2009) Nat Rev Rheumatol. , vol.5 , pp. 229-232
    • Maanen, M.A.1    Vervoordeldonk, M.J.2    Tak, P.P.3
  • 16
    • 0033544431 scopus 로고    scopus 로고
    • Long-term treatment with vagus nerve stimulation in patients with refractory epilepsy. The Vagus Nerve Stimulation Study Group E01-E05
    • Morris 3rd GL, Mueller WM. Long-term treatment with vagus nerve stimulation in patients with refractory epilepsy. The Vagus Nerve Stimulation Study Group E01-E05. Neurology. 1999;53:1731-5.
    • (1999) Neurology. , vol.53 , pp. 1731-1735
    • Morris, G.L.1    Mueller, W.M.2
  • 17
    • 79953787411 scopus 로고    scopus 로고
    • Effectiveness and safety of vagus nerve stimulation for severe treatment-resistant major depression in clinical practice after FDA approval: outcomes at 1 year
    • Cristancho P, Cristancho MA, Baltuch GH, Thase ME, O'Reardon JP. Effectiveness and safety of vagus nerve stimulation for severe treatment-resistant major depression in clinical practice after FDA approval: outcomes at 1 year. J Clin Psychiatry. 2011;72:1376-82.
    • (2011) J Clin Psychiatry. , vol.72 , pp. 1376-1382
    • Cristancho, P.1    Cristancho, M.A.2    Baltuch, G.H.3    Thase, M.E.4    O'Reardon, J.P.5
  • 18
    • 69949182019 scopus 로고    scopus 로고
    • Effects of vagus nerve stimulation on pro- and anti-inflammatory cytokine induction in patients with refractory epilepsy
    • de Herdt V, Bogaert S, Bracke KR, Raedt R, De Vos M, Vonck K, et al. Effects of vagus nerve stimulation on pro- and anti-inflammatory cytokine induction in patients with refractory epilepsy. J Neuroimmunol. 2009;214:104-8.
    • (2009) J Neuroimmunol. , vol.214 , pp. 104-108
    • Herdt, V.1    Bogaert, S.2    Bracke, K.R.3    Raedt, R.4    Vos, M.5    Vonck, K.6
  • 19
    • 84861336207 scopus 로고    scopus 로고
    • Epicardial ganglionated plexus stimulation decreases postoperative inflammatory response in humans
    • Rossi P, Ricci A, De Paulis R, Papi E, Pavaci H, Porcelli D, et al. Epicardial ganglionated plexus stimulation decreases postoperative inflammatory response in humans. Heart Rhythm. 2012;9:943-50.
    • (2012) Heart Rhythm. , vol.9 , pp. 943-950
    • Rossi, P.1    Ricci, A.2    Paulis, R.3    Papi, E.4    Pavaci, H.5    Porcelli, D.6
  • 20
    • 84873751214 scopus 로고    scopus 로고
    • Transvenous vagus nerve stimulation: a potential heart failure therapy is feasible in humans
    • Fan K, Yee R, Gula L, Bentley C, Scheiner A, Lam S, et al. Transvenous vagus nerve stimulation: a potential heart failure therapy is feasible in humans. J Am Coll Cardiol. 2010;55:A16. E152.
    • (2010) J Am Coll Cardiol , vol.55 , pp. A16
    • Fan, K.1    Yee, R.2    Gula, L.3    Bentley, C.4    Scheiner, A.5    Lam, S.6
  • 21
    • 84873751214 scopus 로고    scopus 로고
    • Low amplitude vagus nerve stimulation affects heart rate and neurohormones in humans
    • Fan K, Yee R, Gula L, Bentley C, Scheiner A, Lam S, et al. Low amplitude vagus nerve stimulation affects heart rate and neurohormones in humans. J Am Coll Cardiol. 2010;55:A16. E154.
    • (2010) J Am Coll Cardiol , vol.55 , pp. A16
    • Fan, K.1    Yee, R.2    Gula, L.3    Bentley, C.4    Scheiner, A.5    Lam, S.6
  • 22
    • 0027489870 scopus 로고
    • Hematologic and immunomodulatory effects of an interleukin-1 receptor antagonist coinfusion during low-dose endotoxemia in healthy humans
    • Granowitz EV, Porat R, Mier JW, Orencole SF, Callahan MV, Cannon JG, et al. Hematologic and immunomodulatory effects of an interleukin-1 receptor antagonist coinfusion during low-dose endotoxemia in healthy humans. Blood. 1993;82:2985-90.
    • (1993) Blood. , vol.82 , pp. 2985-2990
    • Granowitz, E.V.1    Porat, R.2    Mier, J.W.3    Orencole, S.F.4    Callahan, M.V.5    Cannon, J.G.6
  • 23
    • 0028811230 scopus 로고
    • Effects of recombinant dimeric TNF receptor on human inflammatory responses following intravenous endotoxin administration
    • Suffredini AF, Reda D, Banks SM, Tropea M, Agosti JM, Miller R. Effects of recombinant dimeric TNF receptor on human inflammatory responses following intravenous endotoxin administration. J Immunol. 1995;155:5038-45.
    • (1995) J Immunol. , vol.155 , pp. 5038-5045
    • Suffredini, A.F.1    Reda, D.2    Banks, S.M.3    Tropea, M.4    Agosti, J.M.5    Miller, R.6
  • 24
    • 35848936089 scopus 로고    scopus 로고
    • From therapy to experimental model: a hundred years of endotoxin administration to human subjects
    • Bahador M, Cross AS. From therapy to experimental model: a hundred years of endotoxin administration to human subjects. J Endotoxin Res. 2007;13:251-79.
    • (2007) J Endotoxin Res. , vol.13 , pp. 251-279
    • Bahador, M.1    Cross, A.S.2
  • 25
    • 79961054751 scopus 로고    scopus 로고
    • Differential ex vivo and in vivo endotoxin tolerance kinetics following human endotoxemia
    • Kox M, de Kleijn S, Pompe JC, Ramakers BP, Netea MG, van der Hoeven JG, et al. Differential ex vivo and in vivo endotoxin tolerance kinetics following human endotoxemia. Crit Care Med. 2011;39:1866-70.
    • (2011) Crit Care Med , vol.39 , pp. 1866-1870
    • Kox, M.1    Kleijn, S.2    Pompe, J.C.3    Ramakers, B.P.4    Netea, M.G.5    Hoeven, J.G.6
  • 26
    • 79959760320 scopus 로고    scopus 로고
    • Effects of the alpha7 nicotinic acetylcholine receptor agonist GTS-21 on the innate immune response in humans
    • Kox M, Pompe JC, de Gouberville MCG, van der Hoeven JG, Hoedemaekers CW, Pickkers P. Effects of the alpha7 nicotinic acetylcholine receptor agonist GTS-21 on the innate immune response in humans. Shock. 2011;36:5-11.
    • (2011) Shock. , vol.36 , pp. 5-11
    • Kox, M.1    Pompe, J.C.2    Gouberville, M.C.G.3    Hoeven, J.G.4    Hoedemaekers, C.W.5    Pickkers, P.6
  • 27
    • 0034904004 scopus 로고    scopus 로고
    • High strength stimulation of the vagus nerve in awake humans: a lack of cardiorespiratory effects
    • Binks AP, Paydarfar D, Schachter SC, Guz A, Banzett RB. High strength stimulation of the vagus nerve in awake humans: a lack of cardiorespiratory effects. Respir Physiol. 2001;127:125-33.
    • (2001) Respir Physiol. , vol.127 , pp. 125-133
    • Binks, A.P.1    Paydarfar, D.2    Schachter, S.C.3    Guz, A.4    Banzett, R.B.5
  • 30
    • 84858425597 scopus 로고    scopus 로고
    • The effects of brain injury on heart rate variability and the innate immune response in critically ill patients
    • Kox M, Vrouwenvelder MQ, Pompe JC, van der Hoeven JG, Pickkers P, Hoedemaekers CW. The effects of brain injury on heart rate variability and the innate immune response in critically ill patients. J Neurotrauma. 2012;29:747-55.
    • (2012) J Neurotrauma. , vol.29 , pp. 747-755
    • Kox, M.1    Vrouwenvelder, M.Q.2    Pompe, J.C.3    Hoeven, J.G.4    Pickkers, P.5    Hoedemaekers, C.W.6
  • 31
    • 17144370981 scopus 로고    scopus 로고
    • Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation
    • Saeed RW, Varma S, Peng-Nemeroff T, Sherry B, Balakhaneh D, Huston J, et al. Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation. J Exp Med. 2005;201:1113-23.
    • (2005) J Exp Med. , vol.201 , pp. 1113-1123
    • Saeed, R.W.1    Varma, S.2    Peng-Nemeroff, T.3    Sherry, B.4    Balakhaneh, D.5    Huston, J.6
  • 32
    • 68849103815 scopus 로고    scopus 로고
    • Vagus nerve activity augments intestinal macrophage phagocytosis via nicotinic acetylcholine receptor alpha4beta2
    • van der Zanden EP, Snoek SA, Heinsbroek SE, Stanisor OI, Verseijden C, Boeckxstaens GE, et al. Vagus nerve activity augments intestinal macrophage phagocytosis via nicotinic acetylcholine receptor alpha4beta2. Gastroenterology. 2009;137:1029-39.
    • (2009) Gastroenterology. , vol.137 , pp. 1029-1039
    • Zanden, E.P.1    Snoek, S.A.2    Heinsbroek, S.E.3    Stanisor, O.I.4    Verseijden, C.5    Boeckxstaens, G.E.6
  • 33
    • 84864295762 scopus 로고    scopus 로고
    • Neural reflexes in inflammation and immunity
    • Andersson U, Tracey KJ. Neural reflexes in inflammation and immunity. J Exp Med. 2012;209:1057-68.
    • (2012) J Exp Med. , vol.209 , pp. 1057-1068
    • Andersson, U.1    Tracey, K.J.2
  • 34
    • 68949127056 scopus 로고    scopus 로고
    • Cholinergic neural signals to the spleen down-regulate leukocyte trafficking via CD11b
    • Huston JM, Rosas-Ballina M, Xue X, Dowling O, Ochani K, Ochani M, et al. Cholinergic neural signals to the spleen down-regulate leukocyte trafficking via CD11b. J Immunol. 2009;183:552-9.
    • (2009) J Immunol. , vol.183 , pp. 552-559
    • Huston, J.M.1    Rosas-Ballina, M.2    Xue, X.3    Dowling, O.4    Ochani, K.5    Ochani, M.6
  • 35
    • 33646817775 scopus 로고    scopus 로고
    • Human endotoxemia: a model for mechanistic insight and therapeutic targeting
    • Lowry SF. Human endotoxemia: a model for mechanistic insight and therapeutic targeting. Shock. 2005;24:94-100.
    • (2005) Shock. , vol.24 , pp. 94-100
    • Lowry, S.F.1
  • 36
    • 84933559581 scopus 로고    scopus 로고
    • Clinicaltrials.gov: Registry and results database of publicly and privately supported clinical studies of human participants conducted around the world
    • Clinicaltrials.gov: Registry and results database of publicly and privately supported clinical studies of human participants conducted around the world: http://www.clinicaltrials.gov.
  • 38
    • 33745830175 scopus 로고    scopus 로고
    • Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis
    • Huston JM, Ochani M, Rosas-Ballina M, Liao H, Ochani K, Pavlov VA, et al. Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis. J Exp Med. 2006;203:1623-8.
    • (2006) J Exp Med. , vol.203 , pp. 1623-1628
    • Huston, J.M.1    Ochani, M.2    Rosas-Ballina, M.3    Liao, H.4    Ochani, K.5    Pavlov, V.A.6
  • 39
    • 44349133469 scopus 로고    scopus 로고
    • Effect of vagal nerve stimulation on systemic inflammation and cardiac autonomic function in patients with refractory epilepsy
    • Barone L, Colicchio G, Policicchio D, Di Clemente F, Di Monaco A, Meglio M, et al. Effect of vagal nerve stimulation on systemic inflammation and cardiac autonomic function in patients with refractory epilepsy. Neuroimmunomodulation. 2007;14:331-6.
    • (2007) Neuroimmunomodulation. , vol.14 , pp. 331-336
    • Barone, L.1    Colicchio, G.2    Policicchio, D.3    Clemente, F.4    Monaco, A.5    Meglio, M.6
  • 40
    • 0042570656 scopus 로고    scopus 로고
    • Analysis of RR variability in drug-resistant epilepsy patients chronically treated with vagus nerve stimulation
    • Galli R, Limbruno U, Pizzanelli C, Giorgi FS, Lutzemberger L, Strata G, et al. Analysis of RR variability in drug-resistant epilepsy patients chronically treated with vagus nerve stimulation. Auton Neurosci. 2003;107:52-9.
    • (2003) Auton Neurosci. , vol.107 , pp. 52-59
    • Galli, R.1    Limbruno, U.2    Pizzanelli, C.3    Giorgi, F.S.4    Lutzemberger, L.5    Strata, G.6
  • 41
    • 33644814406 scopus 로고    scopus 로고
    • Cardiac autonomic control in patients with refractory epilepsy before and during vagus nerve stimulation treatment: a one-year follow-up study
    • Ronkainen E, Korpelainen JT, Heikkinen E, Myllyla VV, Huikuri HV, Isojarvi JI. Cardiac autonomic control in patients with refractory epilepsy before and during vagus nerve stimulation treatment: a one-year follow-up study. Epilepsia. 2006;47:556-62.
    • (2006) Epilepsia. , vol.47 , pp. 556-562
    • Ronkainen, E.1    Korpelainen, J.T.2    Heikkinen, E.3    Myllyla, V.V.4    Huikuri, H.V.5    Isojarvi, J.I.6
  • 43
    • 0037461768 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation
    • Wang H, Yu M, Ochani M, Amella CA, Tanovic M, Susarla S, et al. Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature. 2003;421:384-8.
    • (2003) Nature. , vol.421 , pp. 384-388
    • Wang, H.1    Yu, M.2    Ochani, M.3    Amella, C.A.4    Tanovic, M.5    Susarla, S.6
  • 44
    • 24944445120 scopus 로고    scopus 로고
    • The effects of vagus nerve stimulation on pro- and anti-inflammatory cytokines in humans: a preliminary report
    • Corcoran C, Connor TJ, O'Keane V, Garland MR. The effects of vagus nerve stimulation on pro- and anti-inflammatory cytokines in humans: a preliminary report. Neuroimmunomodulation. 2005;12:307-9.
    • (2005) Neuroimmunomodulation. , vol.12 , pp. 307-309
    • Corcoran, C.1    Connor, T.J.2    O'Keane, V.3    Garland, M.R.4
  • 45
    • 77954548499 scopus 로고    scopus 로고
    • Vagus nerve stimulation in refractory epilepsy: effects on pro- and anti-inflammatory cytokines in peripheral blood
    • Majoie HJ, Rijkers K, Berfelo MW, Hulsman JA, Myint A, Schwarz M, et al. Vagus nerve stimulation in refractory epilepsy: effects on pro- and anti-inflammatory cytokines in peripheral blood. Neuroimmunomodulation. 2011;18:52-6.
    • (2011) Neuroimmunomodulation. , vol.18 , pp. 52-56
    • Majoie, H.J.1    Rijkers, K.2    Berfelo, M.W.3    Hulsman, J.A.4    Myint, A.5    Schwarz, M.6
  • 46
    • 84921927445 scopus 로고    scopus 로고
    • Pilot study of stimulation of the cholinergic anti-inflammatory pathway with an implantable vagus nerve stimulation device in patients with rheumatoid arthritis
    • Koopman FA, Miljko S, Grazio S, Sokolovic S, Tracey K, Levine YA. Pilot study of stimulation of the cholinergic anti-inflammatory pathway with an implantable vagus nerve stimulation device in patients with rheumatoid arthritis. Arthritis Rheum. 2012;64:451.
    • (2012) Arthritis Rheum. , vol.64 , pp. 451
    • Koopman, F.A.1    Miljko, S.2    Grazio, S.3    Sokolovic, S.4    Tracey, K.5    Levine, Y.A.6
  • 47
    • 68949103827 scopus 로고    scopus 로고
    • In vivo lipopolysaccharide exposure of human blood leukocytes induces cross-tolerance to multiple TLR ligands
    • de Vos AF, Pater JM, van den Pangaart PS, Pater JM, de Kruif MD, van't Veer C, et al. In vivo lipopolysaccharide exposure of human blood leukocytes induces cross-tolerance to multiple TLR ligands. J Immunol. 2009;183:533-42.
    • (2009) J Immunol , vol.183 , pp. 533-542
    • Vos, A.F.1    Pater, J.M.2    Pangaart, P.S.3    Pater, J.M.4    Kruif, M.D.5    van't Veer, C.6
  • 48
    • 58149133796 scopus 로고    scopus 로고
    • The effect of systemic iNOS inhibition during human endotoxemia on the development of tolerance to different TLR-stimuli
    • Draisma A, Dorresteijn M, Pickkers P, van der Hoeven H. The effect of systemic iNOS inhibition during human endotoxemia on the development of tolerance to different TLR-stimuli. Innate Immun. 2008;14:153-9.
    • (2008) Innate Immun , vol.14 , pp. 153-159
    • Draisma, A.1    Dorresteijn, M.2    Pickkers, P.3    Hoeven, H.4
  • 49
    • 38449086201 scopus 로고    scopus 로고
    • Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia model
    • van't Veer C, van den Pangaart PS, van Zoelen MA, de Kruif M, Birjmohun RS, Stroes ES, et al. Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia model. J Immunol. 2007;179:7110-20.
    • (2007) J Immunol , vol.179 , pp. 7110-7120
    • van't Veer, C.1    Pangaart, P.S.2    Zoelen, M.A.3    Kruif, M.4    Birjmohun, R.S.5    Stroes, E.S.6
  • 50
    • 77957090814 scopus 로고    scopus 로고
    • Human monocytes tolerant to LPS retain the ability to phagocytose bacteria and generate reactive oxygen species
    • Fernandes ML, Mendes ME, Brunialti MK, Salomao R. Human monocytes tolerant to LPS retain the ability to phagocytose bacteria and generate reactive oxygen species. Braz J Med Biol Res. 2010;43:860-8.
    • (2010) Braz J Med Biol Res. , vol.43 , pp. 860-868
    • Fernandes, M.L.1    Mendes, M.E.2    Brunialti, M.K.3    Salomao, R.4


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