Oxytocin and social cognition in affective and psychotic disorders

European Neuropsychopharmacology

Volumn 25, Issue 2, 2015, Pages 265-282

  Mercedes Perez Rodriguez, M ^a,b,c   Mahon, Katie ^a   Russo, Manuela ^a   Ungar, Allison K ^a   Burdick, Katherine E ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c HOSPITAL UNIVERSITARIO FUNDACIÓN JIMÉNEZ DÍAZ   (Spain)

Author keywords

Bipolar disorder; Major depressive disorder; Oxytocin; Schizophrenia; Social cognition

Indexed keywords

OXYTOCIN; PSYCHOTROPIC AGENT;

ARTICLE; BIPOLAR DISORDER; CLINICAL TRIAL (TOPIC); DEPRESSION; DRUG MECHANISM; EMOTION; HUMAN; MAJOR DEPRESSION; MOOD DISORDER; PRIORITY JOURNAL; PSYCHOSIS; RECOGNITION; SCHIZOPHRENIA; SOCIAL COGNITION; THEORY OF MIND; COGNITION; DRUG EFFECTS; MOOD DISORDERS; PERCEPTION; PSYCHOLOGY; PSYCHOTIC DISORDERS;

CLINICAL TRIALS AS TOPIC; COGNITION; HUMANS; MOOD DISORDERS; OXYTOCIN; PSYCHOTIC DISORDERS; PSYCHOTROPIC DRUGS; SOCIAL PERCEPTION;

EID: 84933280192     PISSN: 0924977X     EISSN: 18737862     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2014.07.012     Document Type: Article

References (193)

1. Aakre J.M., Seghers J.P., St-Hilaire A., Docherty N. Attributional style in delusional patients: a comparison of remitted paranoid, remitted nonparanoid, and current paranoid patients with nonpsychiatric controls. Schizophr. Bull. 2009, 35:994-1002.
2. Achim A.M., Ouellet R., Roy M.A., Jackson P.L. Assessment of empathy in first-episode psychosis and meta-analytic comparison with previous studies in schizophrenia. Psychiatry Res. 2011, 190:3-8.
3. Addington J., Addington D. Facial affect recognition and information processing in schizophrenia and bipolar disorder. Schizophr. Res. 1998, 32:171-181.
4. Addington J., Piskulic D., Perkins D., Woods S.W., Liu L., Penn D.L. Affect recognition in people at clinical high risk of psychosis. Schizophr. Res. 2012, 140:87-92.
5. Alloy L.B., Lipman A.J., Abramson L.Y. Attributional style as a vulnerability factor for depression: validation by past history of mood disorders. Cognit. Ther. Res. 1992, 16:391-407.
6. Amminger G.P., Schäfer M.R., Papageorgiou K., Klier C.M., Schlögelhofer M., Mossaheb N., Werneck-Rohrer S., Nelson B., McGorry P.D. Emotion recognition in individuals at clinical high-risk for schizophrenia. Schizophr. Bull. 2012, 38:1030-1039.
7. Andero R., Ressler K.J. Fear extinction and BDNF: translating animal models of PTSD to the clinic. Genes Brain Behav. 2012, 11:503-512.
8. Apter-Levy Y., Feldman M., Vakart A., Ebstein R.P., Feldman R. Impact of maternal depression across the first 6 years of life on the child's mental health, social engagement, and empathy: the moderating role of oxytocin. Am. J. Psychiatry 2013, 170:1161-1168.
9. Averbeck B.B., Bobin T., Evans S., Shergill S.S. Emotion recognition and oxytocin in patients with schizophrenia. Psychol. Med. 2012, 42:259-266.
10. Bakermans-Kranenburg M.J., van I.J.M.H. Sniffing around oxytocin: review and meta-analyses of trials in healthy and clinical groups with implications for pharmacotherapy. Transl. Psychiatry 2013, 3:e258.
11. Ball H.A., McGuffin P., Farmer A.E. Attributional style and depression. Br. J. Psychiatry 2008, 192:275-278.
12. Baron-Cohen S., Wheelwright S., Hill J., Raste Y., Plumb I. The "Reading the Mind in the Eyes" test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism. J. Child Psychol. Psychiatry 2001, 42:241-251.
13. Bartz J., Simeon D., Hamilton H., Kim S., Crystal S., Braun A., Vicens V., Hollander E. Oxytocin can hinder trust and cooperation in borderline personality disorder. Soc. Cognit. Affect. Neurosci. 2011, 6:556-563.
14. Bartz J.A., Zaki J., Bolger N., Hollander E., Ludwig N.N., Kolevzon A., Ochsner K.N. Oxytocin selectively improves empathic accuracy. Psychol. Sci. 2010, 21:1426-1428.
15. Bartz J.A., Zaki J., Bolger N., Ochsner K.N. Social effects of oxytocin in humans: context and person matter. Trends Cognit. Sci. 2011, 15:301-309.
16. Bazin N., Brunet-Gouet E., Bourdet C., Kayser N., Falissard B., Hardy-Baylé M.-C., Passerieux C. Quantitative assessment of attribution of intentions to others in schizophrenia using an ecological video-based task: a comparison with manic and depressed patients. Psychiatry Res. 2009, 167:28-35.
17. Bentall R.P., Corcoran R., Howard R., Blackwood N., Kinderman P. Persecutory delusions: a review and theoretical integration. Clin. Psychol. Rev. 2001, 21:1143-1192.
18. Bertrand M.C., Sutton H., Achim A.M., Malla A.K., Lepage M. Social cognitive impairments in first episode psychosis. Schizophr. Res. 2007, 95:124-133.
19. Bertsch K., Gamer M., Schmidt B., Schmidinger I., Walther S., Kastel T., Schnell K., Buchel C., Domes G., Herpertz S.C. Oxytocin and reduction of social threat hypersensitivity in women with borderline personality disorder. Am. J. Psychiatry 2013, 170:1169-1177.
20. Bielsky I.F., Young L.J. Oxytocin, vasopressin, and social recognition in mammals. Peptides 2004, 25:1565-1574.
21. Billeke P., Aboitiz F. Social cognition in schizophrenia: from social stimuli processing to social engagement. Front Psychiatry 2013, 4:4.
22. Bora E., Vahip S., Gonul A.S., Akdeniz F., Alkan M., Ogut M., Eryavuz A. Evidence for theory of mind deficits in euthymic patients with bipolar disorder. Acta Psychiatr. Scand. 2005, 112:110-116.
23. Bora E., Yucel M., Pantelis C. Cognitive endophenotypes of bipolar disorder: a meta-analysis of neuropsychological deficits in euthymic patients and their first-degree relatives. J. Affect. Disord. 2009, 113:1-20.
24. Bora E., Yucel M., Pantelis C. Theory of mind impairment in schizophrenia: meta-analysis. Schizophr. Res. 2009, 109:1-9.
25. Born J., Lange T., Kern W., McGregor G.P., Bickel U., Fehm H.L. Sniffing neuropeptides: a transnasal approach to the human brain. Nat. Neurosci. 2002, 5:514-516.
26. Bos P.A., Panksepp J., Bluthe R.M., van Honk J. Acute effects of steroid hormones and neuropeptides on human social-emotional behavior: a review of single administration studies. Front. Neuroendocrinol. 2012, 33:17-35.
27. Bourke C., Douglas K., Porter R. Processing of facial emotion expression in major depression: a review. Aust. N. Z. J. Psychiatry 2010, 44:681-696.
28. Bozikas V.P., Kosmidis M.H., Anezoulaki D., Giannakou M., Karavatos A. Relationship of affect recognition with psychopathology and cognitive performance in schizophrenia. J. Int. Neuropsychol. Soc. 2004, 10:549-558.
29. Brüne M. Emotion recognition, 'theory of mind,' and social behavior in schizophrenia. Psychiatry Res. 2005, 133:135-147.
30. Brune M., Abdel-Hamid M., Lehmkamper C., Sonntag C. Mental state attribution, neurocognitive functioning, and psychopathology: what predicts poor social competence in schizophrenia best?. Schizophr. Res. 2007, 92:151-159.
31. Brune M., Ebert A., Kolb M., Tas C., Edel M.A., Roser P. Oxytocin influences avoidant reactions to social threat in adults with borderline personality disorder. Hum. Psychopharmacol. 2013, 28:552-561.
32. Bryant R.A., Hung L. Oxytocin enhances social persuasion during hypnosis. PloS One 2013, 8:e60711.
33. Chan R.C., Li H., Cheung E.F., Gong Q.Y. Impaired facial emotion perception in schizophrenia: a meta-analysis. Psychiatry Res. 2010, 178:381-390.
34. Churchland P.S., Winkielman P. Modulating social behavior with oxytocin: how does it work? What does it mean?. Horm. Behav. 2012, 61:392-399.
35. Combs D.R., Adams S.D., Penn D.L., Roberts D., Tiegreen J., Stem P. Social Cognition and Interaction Training (SCIT) for inpatients with schizophrenia spectrum disorders: preliminary findings. Schizophr. Res. 2007, 91:112-116.
36. Corcoran R., Frith C.D. Autobiographical memory and theory of mind: evidence of a relationship in schizophrenia. Psychol Med. 2003, 33:897-905.
37. Corcoran R., Mercer G., Frith C.D. Schizophrenia, symptomatology and social inference: investigating "theory of mind" in people with schizophrenia. Schizophr. Res. 1995, 17:5-13.
38. Couture S.M., Penn D.L., Roberts D.L. The functional significance of social cognition in schizophrenia: a review. Schizophr. Bull. 2006, 32(Suppl 1):S44-S63.
39. Cusi A.M., Nazarov A., Macqueen G.M., McKinnon M.C. Theory of mind deficits in patients with mild symptoms of major depressive disorder. Psychiatry Res. 2013, 210:672-674.
40. Cyranowski J.M., Hofkens T.L., Frank E., Seltman H., Cai H.-M., Amico J.A. Evidence of dysregulated peripheral oxytocin release among depressed women. Psychosom. Med. 2008, 70:967-975.
41. Davis M.H. Measuring individual differences in empathy: evidence for a multidimensional approach. J. Personal. Soc. Psychol. 1983, 44:113-126.
42. Davis M.C., Green M.F., Lee J., Horan W.P., Senturk D., Clarke A.D., Marder S.R. Oxytocin-augmented social cognitive skills training in schizophrenia. Neuropsychopharmacol. 2014, 39:2070-2077.
43. Derntl B., Finkelmeyer A., Toygar T.K., Hülsmann A., Schneider F., Falkenberg D.I., Habel U. Generalized deficit in all core components of empathy in schizophrenia. Schizophr. Res. 2009, 108:197-206.
44. Devylder J.E., Ben-David S., Kimhy D., Corcoran C.M. Attributional style among youth at clinical risk for psychosis. Early Interv. Psychiatry 2013, 7:84-88.
45. Ditzen B., Schaer M., Gabriel B., Bodenmann G., Ehlert U., Heinrichs M. Intranasal oxytocin increases positive communication and reduces cortisol levels during couple conflict. Biol. Psychiatry 2009, 65:728-731.
46. Domes G., Lischke A., Berger C., Grossmann A., Hauenstein K., Heinrichs M., Herpertz S.C. Effects of intranasal oxytocin on emotional face processing in women. Psychoneuroendocrinology 2010, 35:83-93.
47. Domes G., Sibold M., Schulze L., Lischke A., Herpertz S.C., Heinrichs M. Intranasal oxytocin increases covert attention to positive social cues. Psychol. Med. 2013, 43:1747-1753.
48. Doop M.L., Park S. Facial expression and face orientation processing in schizophrenia. Psychiatry Res. 2009, 170:103-107.
49. Drury V.M., Robinson E.J., Birchwood M. 'Theory of mind' skills during an acute episode of psychosis and following recovery. Psychol. Med. 1998, 28:1101-1112.
50. Dziobek I., Fleck S., Kalbe E., Rogers K., Hassenstab J., Brand M., Convit A. Introducing MASC: a movie for the assessment of social cognition. J. Autism Dev. Disord. 2006, 36:623-636.
51. Ebert A., Kolb M., Heller J., Edel M.A., Roser P., Brune M. Modulation of interpersonal trust in borderline personality disorder by intranasal oxytocin and childhood trauma. Soc. Neurosci. 2013, 8:305-313.
52. Edwards J., Pattison P.E., Jackson H.J., Wales R.J. Facial affect and affective prosody recognition in first-episode schizophrenia. Schizophr. Res. 2001, 48:235-253.
53. Eisenberg N., Miller P.A. The relation of empathy to prosocial and related behaviors. Psychol. Bull. 1987, 101:91-119.
54. Ellenbogen M.A., Linnen A.-M., Cardoso C., Joober R. Intranasal oxytocin impedes the ability to ignore task-irrelevant facial expressions of sadness in students with depressive symptoms. Psychoneuroendocrinology 2013, 38:387-398.
55. Elvevåg B., Goldberg T.E. Cognitive impairment in schizophrenia is the core of the disorder. Crit. Rev. Neurobiol. 2000, 14:1-21.
56. Feifel D., Macdonald K., Cobb P., Minassian A. Adjunctive intranasal oxytocin improves verbal memory in people with schizophrenia. Schizophr. Res. 2012, 139:207-210.
57. Feifel D., Macdonald K., Nguyen A., Cobb P., Warlan H., Galangue B., Minassian A., Becker O., Cooper J., Perry W., Lefebvre M., Gonzales J., Hadley A. Adjunctive intranasal oxytocin reduces symptoms in schizophrenia patients. Biol. Psychiatry 2010, 68:678-680.
58. Fett A.K., Viechtbauer W., Dominguez M.D., Penn D.L., van Os J., Krabbendam L. The relationship between neurocognition and social cognition with functional outcomes in schizophrenia: a meta-analysis. Neurosci. Biobehav. Rev. 2011, 35:573-588.
59. Fioravanti M., Carlone O., Vitale B., Cinti M.E., Clare L. A meta-analysis of cognitive deficits in adults with a diagnosis of schizophrenia. Neuropsychol. Rev. 2005, 15:73-95.
60. Fischer-Shofty M., Brüne M., Ebert A., Shefet D., Levkovitz Y., Shamay-Tsoory S.G. Improving social perception in schizophrenia: the role of oxytocin. Schizophr. Res. 2013, 146:357-362.
61. Fischer-Shofty M., Shamay-Tsoory S.G., Levkovitz Y. Characterization of the effects of oxytocin on fear recognition in patients with schizophrenia and in healthy controls. Front. Neurosci. 2013, 7:127.
62. Frith C.D. Social cognition. Philos. Trans. R. Soc. Lond. B 2008, 363:2033-2039.
63. Fyfe S., Williams C., Mason O.J., Pickup G.J. Apophenia, theory of mind and schizotypy: perceiving meaning and intentionality in randomness. Cortex 2008, 44:1316-1325.
64. Gaebel W., Wölwer W. Facial expression and emotional face recognition in schizophrenia and depression. Eur. Arch. Psychiatry Clin. Neurosci. 1992, 242:46-52.
65. Garety P.A., Freeman D. Cognitive approaches to delusions: a critical review of theories and evidence. Br. J. Clin. Psychol. 1999, 38:113-154.
66. Goldberg T.E., Goldman R.S., Burdick K.E., Malhotra A.K., Lencz T., Patel R.C., Woerner M.G., Schooler N.R., Kane J.M., Robinson D.G. Cognitive improvement after treatment with second-generation antipsychotic medications in first-episode schizophrenia: is it a practice effect?. Arch. Gen. Psychiatry 2007, 64:1115-1122.
67. Goldman M.B., Gomes A.M., Carter C.S., Lee R. Divergent effects of two different doses of intranasal oxytocin on facial affect discrimination in schizophrenic patients with and without polydipsia. Psychopharmacology 2011, 216:101-110.
68. Gollan J.K., Pane H.T., McCloskey M.S., Coccaro E.F. Identifying differences in biased affective information processing in major depression. Psychiatry Res. 2008, 159:18-24.
69. Gooding D.C., Pflum M.J. Theory of mind and psychometric schizotypy. Psychiatry Res. 2011, 188:217-223.
70. Gordon I., Zagoory-Sharon O., Schneiderman I., Leckman J.F., Weller A., Feldman R. Oxytocin and cortisol in romantically unattached young adults: associations with bonding and psychological distress. Psychophysiology 2008, 45:349-352.
71. Green M.F. Cognitive impairment and functional outcome in schizophrenia and bipolar disorder. J. Clin. Psychiatry 2006, 67:e12.
72. Green M.F., Bearden C.E., Cannon T.D., Fiske A.P., Hellemann G.S., Horan W.P., Kee K., Kern R.S., Lee J., Sergi M.J., Subotnik K.L., Sugar C.A., Ventura J., Yee C.M., Nuechterlein K.H. Social cognition in schizophrenia, Part 1: performance across phase of illness. Schizophr. Bull. 2012, 38:854-864.
73. Green M.F., Leitman D.I. Social cognition in schizophrenia. Schizophr. Bull. 2008, 34:670-672.
74. Groppe S.E., Gossen A., Rademacher L., Hahn A., Westphal L., Grunder G., Spreckelmeyer K.N. Oxytocin influences processing of socially relevant cues in the ventral tegmental area of the human brain. Biol. Psychiatry 2013, 74:172-179.
75. Guastella A.J., Hickie I.B., McGuinness M.M., Otis M., Woods E.A., Disinger H.M., Chan H.K., Chen T.F., Banati R.B. Recommendations for the standardisation of oxytocin nasal administration and guidelines for its reporting in human research. Psychoneuroendocrinology 2013, 38:612-625.
76. Guastella A.J., Howard A.L., Dadds M.R., Mitchell P., Carson D.S. A randomized controlled trial of intranasal oxytocin as an adjunct to exposure therapy for social anxiety disorder. Psychoneuroendocrinology 2009, 34:917-923.
77. Gumley A., Braehler C., Macbeth A. A meta-analysis and theoretical critique of oxytocin and psychosis: prospects for attachment and compassion in promoting recovery. Br. J. Clin. Psychol. 2014, 53:42-61.
78. Happé F.G. An advanced test of theory of mind: understanding of story characters' thoughts and feelings by able autistic, mentally handicapped, and normal children and adults. J. Autism Dev. Disord. 1994, 24:129-154.
79. Harvey P.D., Bowie C.R. Cognitive enhancement in schizophrenia: pharmacological and cognitive remediation approaches. Psychiatr. Clin. N. Am. 2012, 35:683-698.
80. Heinrichs M., Baumgartner T., Kirschbaum C., Ehlert U. Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress. Biol. Psychiatry 2003, 54:1389-1398.
81. Heinrichs R.W., Zakzanis K.K. Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology 1998, 12:426-445.
82. Henderson A.R. The impact of social cognition training on recovery from psychosis. Curr. Opin. Psychiatry 2013, 26:429-432.
83. Hirschfeld R.M., Montgomery S.A., Keller M.B., Kasper S., Schatzberg A.F., Möller H.J., Bourgeois M. Social functioning in depression: a review. J. Clin. Psychiatry 2000, 61:268-275.
84. Hoekert M., Kahn R.S., Pijnenborg M., Aleman A. Impaired recognition and expression of emotional prosody in schizophrenia: review and meta-analysis. Schizophr. Res. 2007, 96:135-145.
85. Hooker C., Park S. Emotion processing and its relationship to social functioning in schizophrenia patients. Psychiatry Res. 2002, 112:41-50.
86. Inoue Y., Tonooka Y., Yamada K., Kanba S. Deficiency of theory of mind in patients with remitted mood disorder. J. Affect. Disord. 2004, 82:403-409.
87. Inoue Y., Yamada K., Kanba S. Deficit in theory of mind is a risk for relapse of major depression. J. Affect. Disord. 2006, 95:125-127.
88. Insel T., Cuthbert B., Garvey M., Heinssen R., Pine D.S., Quinn K., Sanislow C., Wang P. Research domain criteria (RDoC): toward a new classification framework for research on mental disorders. Am. J. Psychiatry 2010, 167:748-751.
89. Kaney S., Bentall R.P. Persecutory delusions and attributional style. Br. J. Med. Psychol. 1989, 62:191-198.
90. Keri S., Kiss I. Oxytocin response in a trust game and habituation of arousal. Physiol. Behav. 2011, 102:221-224.
91. Kerr N., Dunbar R.I.M., Bentall R.P. Theory of mind deficits in bipolar affective disorder. J. Affect. Disord. 2003, 73:253-259.
92. Kettle J.W., O'Brien-Simpson L., Allen N.B. Impaired theory of mind in first-episode schizophrenia: comparison with community, university and depressed controls. Schizophr. Res. 2008, 99:96-102.
93. Kim, S., Fonagy, P., Koos, O., Michael, K., Strathearn, L., Maternal oxytocin response predicts mother-to-infant gaze. Brain Res. , in press. http://dx.doi.org/10.1016/j.brainres.2013.10.050.
94. Koelkebeck K., Pedersen A., Suslow T., Kueppers K.A., Arolt V., Ohrmann P. Theory of mind in first-episode schizophrenia patients: correlations with cognition and personality traits. Schizophr. Res. 2010, 119:115-123.
95. Kohler C.G., Hoffman L.J., Eastman L.B., Healey K., Moberg P.J. Facial emotion perception in depression and bipolar disorder: a quantitative review. Psychiatry Res. 2011, 188:303-309.
96. Kohler C.G., Walker J.B., Martin E.A., Healey K.M., Moberg P.J. Facial emotion perception in schizophrenia: a meta-analytic review. Schizophr. Bull. 2010, 36:1009-1019.
97. Kraepelin E. Manic Depressive Insanity and Paranoia 1921, E.& S. Livingston, Edinburgh. G.M. Robertson (Ed.).
98. Krstev H., Jackson H., Maude D. An investigation of attributional style in first-episode psychosis. Br. J. Clin. Psychol. 1999, 38:181-194.
99. Kurtz M.M., Richardson C.L. Social cognitive training for schizophrenia: a meta-analytic investigation of controlled research. Schizoph. Bull. 2012, 38:1092-1104.
100. Ladegaard N., Larsen E.R., Videbech P., Lysaker P.H. Higher-order social cognition in first-episode major depression. Psychiatry Res. 2013, 216:37-43.
101. Lahera G., Montes J.M., Benito A., Valdivia M., Medina E., Mirapeix I., Saiz-Ruiz J. Theory of mind deficit in bipolar disorder: is it related to a previous history of psychotic symptoms?. Psychiatry Res. 2008, 161:309-317.
102. Lahera G., Benito A., Montes J.M., Fernández-Liria A., Olbert C.M., Penn D.L. Social cognition and interaction training (SCIT) for outpatients with bipolar disorder. J. Affect. Disord. 2013, 146:132-136.
103. Lee L., Harkness K.L., Sabbagh M.A., Jacobson J.A. Mental state decoding abilities in clinical depression. J. Affect. Disord. 2005, 86:247-258.
104. Lee M.R., Wehring H.J., McMahon R.P., Linthicum J., Cascella N., Liu F., Bellack A., Buchanan R.W., Strauss G.P., Contoreggi C., Kelly D.L. Effects of adjunctive intranasal oxytocin on olfactory identification and clinical symptoms in schizophrenia: results from a randomized double blind placebo controlled pilot study. Schizophr. Res. 2013, 145:110-115.
105. Leknes S., Wessberg J., Ellingsen D.M., Chelnokova O., Olausson H., Laeng B. Oxytocin enhances pupil dilation and sensitivity to 'hidden' emotional expressions. Soc. Cognit. Affect. Neurosci. 2013, 8:741-749.
106. Lembke A., Ketter T.A. Impaired recognition of facial emotion in mania. Am. J. Psychiatry 2002, 152:302-304.
107. Leppänen J.M., Milders M., Bell J.S., Terriere E., Hietanen J.K. Depression biases the recognition of emotionally neutral faces. Psychiatry Res. 2004, 128:123-133.
108. Leppänen J.M. Emotional information processing in mood disorders: a review of behavioral and neuroimaging findings. Curr. Opin. Psychiatry 2006, 19:34-39.
109. Li H., Chan R.C., McAlonan G.M., Gong Q.Y. Facial emotion processing in schizophrenia: a meta-analysis of functional neuroimaging data. Schizophr. Bull. 2010, 36:1029-1039.
110. Lincoln T.M., Lange J., Burau J., Exner C., Moritz S. The effect of state anxiety on paranoid ideation and jumping to conclusions. An experimental investigation. Schizophr. Bull. 2010, 36:1140-1148.
111. Loughland C.M., Williams L.M., Gordon E. Schizophrenia and affective disorder show different visual scanning behavior for faces: a trait versus state-based distinction? Biol. Psychiatry 2002, 52:338-348.
112. Love T.M. Oxytocin, motivation and the role of dopamine. Pharmacol. Biochem. Behav. 2014, 119C:49-60.
113. Maat A., Cahn W., Gijsman H.J., Hovens J.E., Kahn R.S., Aleman A. Open, randomized trial of the effects of aripiprazole versus risperidone on social cognition in schizophrenia. Eur Neuropsychopharmacol. 2014, 24:575-584.
114. Macdonald K., Feifel D. Oxytocin in schizophrenia: a review of evidence for its therapeutic effects. Acta Neuropsychiatr. 2012, 24:130-146.
115. Macdonald K., Macdonald T.M. The peptide that binds: a systematic review of oxytocin and its prosocial effects in humans. Harv. Rev. Psychiatry 2010, 18:1-21.
116. MacDonald K., MacDonald T.M., Brune M., Lamb K., Wilson M.P., Golshan S., Feifel D. Oxytocin and psychotherapy: a pilot study of its physiological, behavioral and subjective effects in males with depression. Psychoneuroendocrinology 2013, 38:2831-2843.
117. Mah B.L., Bakermans-Kranenburg M.J., Van Ijzendoorn M.H., Smith R. Oxytocin promotes protective behavior in depressed mothers: a pilot study with the enthusiastic stranger paradigm. Depress. Anxiety 2014, in press. 10.1002/da.22245.
118. Mah B.L., Van Ijzendoorn M.H., Smith R., Bakermans-Kranenburg M.J. Oxytocin in postnatally depressed mothers: its influence on mood and expressed emotion. Prog. Neuropsychopharmacol. Biol. Psychiatry 2013, 40:267-272.
119. Malaspina D., Coleman E. Olfaction and social drive in schizophrenia. Arch. Gen. Psychiatry 2003, 60:578-584.
120. Mancuso F., Horan W.P., Kern R.S., Green M.F. Social cognition in psychosis: multidimensional structure, clinical correlates, and relationship with functional outcome. Schizophrenia Research 2011, 125:143-151.
121. Martínez-Arán A., Penadés R., Vieta E., Colom F., Reinares M., Benabarre A., Salamero M., Gastó C. Executive function in patients with remitted bipolar disorder and schizophrenia and its relationship with functional outcome. Psychother. Psychosom. 2002, 71:39-46.
122. Martino D.J., Strejilevich S.A., Fassi G., Marengo E., Igoa A. Theory of mind and facial emotion recognition in euthymic bipolar I and bipolar II disorders. Psychiatry Res. 2011, 189:379-384.
123. Mazza M., De Risio A., Surian L., Roncone R., Casacchia M. Selective impairments of theory of mind in people with schizophrenia. Schizophr. Res. 2001, 47:299-308.
124. McDonald S., Bornhofen C., Shum D., Long E., Saunders C., Neulinger K. Reliability and validity of The Awareness of Social Inference Test (TASIT): a clinical test of social perception. Disabil. Rehabil. 2006, 28:1529-1542.
125. McKinnon M.C., Cusi A.M., Macqueen G.M. Impaired theory of mind performance in patients with recurrent bipolar disorder: moderating effect of cognitive load. Psychiatry Res. 2010, 177:261-262.
126. Meyer-Lindenberg A., Domes G., Kirsch P., Heinrichs M. Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine. Nat. Rev. Neurosci. 2011, 12:524-538.
127. Meyer-Lindenberg A., Tost H. Neural mechanisms of social risk for psychiatric disorders. Nat. Neurosci. 2012, 15:663-668.
128. Miklowitz D.J. Functional impairment, stress, and psychosocial intervention in bipolar disorder. Curr. Psychiatry Rep. 2011, 13:504-512.
129. Millan M.J., Bales K.L. Towards improved animal models for evaluating social cognition and its disruption in schizophrenia: the CNTRICS initiative. Neurosci. Biobehav. Rev. 2013, 37:2166-2180.
130. Millan M.J., Fone K., Steckler T., Horan W.P. Negative symptoms of schizophrenia: clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment. Eur. Neuropsychopharmacol. 2014, 24:645-692.
131. Miller D., Ross M. Self-serving Biases in the Attribution of Causality: Fact or Fiction?. Psychol Bull. 1975, 82:213-225.
132. Mitchley N.J., Barber J., Gray Y.M., Brooks N., Livingston M.G. Comprehension of irony in schizophrenia. Cognit. Neuropsychiatry 1998, 3:127-138.
133. Modabbernia A., Rezaei F., Salehi B., Jafarinia M., Ashrafi M., Tabrizi M., Hosseini S.M., Tajdini M., Ghaleiha A., Akhondzadeh S. Intranasal oxytocin as an adjunct to risperidone in patients with schizophrenia: an 8-week, randomized, double-blind, placebo-controlled study. CNS Drugs 2013, 27:57-65.
134. Montag C., Dziobek I., Richter I.S., Neuhaus K., Lehmann A., Sylla R., Heekeren H.R., Heinz A., Gallinat J. Different aspects of theory of mind in paranoid schizophrenia: evidence from a video-based assessment. Psychiatry Res. 2011, 186:203-209.
135. Montag C., Ehrlich A., Neuhaus K., Dziobek I., Heekeren H.R., Heinz A., Gallinat J. Theory of mind impairments in euthymic bipolar patients. J. Affect. Disord. 2010, 123:264-269.
136. Neumann I.D., Landgraf R. Balance of brain oxytocin and vasopressin: implications for anxiety, depression, and social behaviors. Trends Neurosci. 2012, 35:649-659.
137. Neumann I.D., Maloumby R., Beiderbeck D.I., Lukas M., Landgraf R. Increased brain and plasma oxytocin after nasal and peripheral administration in rats and mice. Psychoneuroendocrinology 2013, 38:1985-1993.
138. Nuechterlein K.H., Barch D.M., Gold J.M., Goldberg T.E., Green M.F., Heaton R.K. Identification of separable cognitive factors in schizophrenia. Schizophr. Res. 2004, 72:29-39.
139. Ochsner K.N. The social-emotional processing stream: five core constructs and their translational potential for schizophrenia and beyond. Biol Psychiatry 2008, 64:48-61.
140. Pedersen C.A., Gibson C.M., Rau S.W., Salimi K., Smedley K.L., Casey R.L., Leserman J., Jarskog L.F., Penn D.L. Intranasal oxytocin reduces psychotic symptoms and improves Theory of Mind and social perception in schizophrenia. Schizophr. Res. 2011, 132:50-53.
141. Penn D.L., Corrigan P.W., Bentall R.P., Racenstein J.M., Newman L. Social cognition in schizophrenia. Psychol. Bull. 1997, 121:114-132.
142. Penn D., Ritchie M., Francis J., Combs D., Martin J. Social perception in schizophrenia: the role of context. Psychiatry Res. 2002, 109:149-159.
143. Penn D., Roberts D.L., Munt E.D., Silverstein E., Jones N., Sheitman B. A pilot study of social cognition and interaction training (SCIT) for schizophrenia. Schizophr. Res. 2005, 80:357-359.
144. Penn D.L., Sanna L.J., Roberts D.L. Social cognition in schizophrenia: an overview. Schizophr. Bull. 2008, 34:408-411.
145. Perlick D., Stastny P., Mattis S., Teresi J. Contribution of family, cognitive and clinical dimensions to long-term outcome in schizophrenia. Schizophr. Res. 1992, 6:257-265.
146. Perry A., Bentin S., Shalev I., Israel S., Uzefovsky F., Bar-On D., Ebstein R.P. Intranasal oxytocin modulates EEG mu/alpha and beta rhythms during perception of biological motion. Psychoneuroendocrinology 2010, 35:1446-1453.
147. Pflum M.J., Gooding D.C., White H.J. Hint, hint: theory of mind performance in schizotypal individuals. J. Nerv. Ment. Dis. 2013, 201:394-399.
148. Pinkham A.E., Hopfinger J.B., Ruparel K., Penn D.L. An investigation of the relationship between activation of a social cognitive neural network and social functioning. Schizophr. Bull. 2008, 34:688-697.
149. Pinkham A.E., Loughead J., Ruparel K., Overton E., Gur R.E., Gur R.C. Abnormal modulation of amygdala activity in schizophrenia in response to direct- and averted-gaze threat-related facial expressions. Am. J. Psychiatry 2011, 168:293-301.
150. Pinkham A.E., Penn D.L., Perkins D.O., Graham K.A., Siegel M. Emotion perception and social skill over the course of psychosis: a comparison of individuals "at-risk" for psychosis and individuals with early and chronic schizophrenia spectrum illness. Cognit. Neuropsychiatry 2007, 12:198-212.
151. Prehn K., Kazzer P., Lischke A., Heinrichs M., Herpertz S.C., Domes G. Effects of intranasal oxytocin on pupil dilation indicate increased salience of socioaffective stimuli. Psychophysiology 2013, 50:528-537.
152. Quirin M., Kuhl J., Dusing R. Oxytocin buffers cortisol responses to stress in individuals with impaired emotion regulation abilities. Psychoneuroendocrinology 2011, 36:898-904.
153. Reichenberg A., Harvey P.D., Bowie C.R., Mojtabai R., Rabinowitz J., Heaton R.K., Bromet E. Neuropsychological function and dysfunction in schizophrenia and psychotic affective disorders. Schizophr. Bull. 2009, 35:1022-1029.
154. Riem M.M., Bakermans-Kranenburg M.J., Pieper S., Tops M., Boksem M.A., Vermeiren R.R., van Ijzendoorn M.H., Rombouts S.A. Oxytocin modulates amygdala, insula, and inferior frontal gyrus responses to infant crying: a randomized controlled trial. Biol. Psychiatry 2011, 70:291-297.
155. Riem M.M., van IJzendoorn M.H., Tops M., Boksem M.A., Rombouts S.A., Bakermans-Kranenburg M.J. Oxytocin effects on complex brain networks are moderated by experiences of maternal love withdrawal. Eur. Neuropsychopharmacol. 2013, 23:1288-1295.
156. Ripoll L.H., Zaki J., Perez-Rodriguez M.M., Snyder R., Strike K.S., Boussi A., Bartz J.A., Ochsner K.N., Siever L.J., New A.S. Empathic accuracy and cognition in schizotypal personality disorder. Psychiatry Res. 2013, 210:232-241.
157. Roberts D.L., Penn D.L. Social cognition and interaction training (SCIT) for outpatients with schizophrenia: a preliminary study. Psychiatry Res. 2009, 166:141-147.
158. Roberts D.L., Combs D.R., Willoughby M., Mintz J., Gibson C., Rupp B., Penn D.L. A randomized, controlled trial of Social Cognition and Interaction Training (SCIT) for outpatients with schizophrenia spectrum disorders. Br. J. Clin. Psychol. 2014, 53:281-298.
159. Roncone R., Falloon I.R., Mazza M., De Risio A., Pollice R., Necozione S., Morosini P., Casacchia M. Is theory of mind in schizophrenia more strongly associated with clinical and social functioning than with neurocognitive deficits?. Psychopathology 2002, 35:280-288.
160. Sabatinelli D., Fortune E.E., Li Q., Siddiqui A., Krafft C., Oliver W.T., Jeffries J. Emotional perception: meta-analyses of face and natural scene processing. Neuroimage 2011, 54:2524-2533.
161. Samamé C., Martino D.J., Strejilevich S.A. Social cognition in euthymic bipolar disorder: systematic review and meta-analytic approach. Acta Psychiatr. Scand. 2012, 125:266-280.
162. Sarfati Y., Hardy-Baylé M.C., Brunet E., Widlöcher D. Investigating theory of mind in schizophrenia: influence of verbalization in disorganized and non-disorganized patients. Schizophr. Res. 1999, 37:183-190.
163. Scantamburlo G., Hansenne M., Fuchs S., Pitchot W., Maréchal P., Pequeux C., Legros J.J. Plasma oxytocin levels and anxiety in patients with major depression. Psychoneuroendocrinology 2007, 32:407-410.
164. Schreiter S., Pijnenborg G.H.M., Rot, M.Aan Het Empathy in adults with clinical or subclinical depressive symptoms. J. Affect. Disord. 2013, 150:1-16.
165. Sharp C., Ha C., Carbone C., Kim S., Perry K., Williams L., Fonagy P. Hypermentalizing in adolescent inpatients: treatment effects and association with borderline traits. J. Pers. Disord. 2013, 27:3-18. 10.1521/pedi.2013.27.1.3.
166. Sharp C., Pane H., Ha C., Venta A., Patel A.B., Sturek J., Fonagy P. Theory of mind and emotion regulation difficulties in adolescents with borderline traits. J. Am. Acad. Child Adolesc. Psychiatry 2011, 50:563-573. (e561).
167. Shea T.L., Sergejew A.A., Burnham D., Jones C., Rossell S.L., Copolov D.L., Egan G.F. Emotional prosodic processing in auditory hallucinations. Schizophr. Res. 2007, 90:214-220.
168. Simeon D., Bartz J., Hamilton H., Crystal S., Braun A., Ketay S., Hollander E. Oxytocin administration attenuates stress reactivity in borderline personality disorder: a pilot study. Psychoneuroendocrinology 2011, 36:1418-1421.
169. Smith A.L., Freeman S.M., Stehouwer J.S., Inoue K., Voll R.J., Young L.J., Goodman M.M. Synthesis and evaluation of C-11, F-18 and I-125 small molecule radioligands for detecting oxytocin receptors. Bioorg. Med. Chem. 2012, 20:2721-2738.
170. Smith A.L., Freeman S.M., Voll R.J., Young L.J., Goodman M.M. Investigation of an F-18 oxytocin receptor selective ligand via PET imaging. Bioorg. Med. Chem. Lett. 2013, 23:5415-5420.
171. Sprong M., Schothorst P., Vos E., Hox J., van Engeland H. Theory of mind in schizophrenia: meta-analysis. Br. J. Psychiatry 2007, 191:5-13.
172. Sripada C.S., Phan K.L., Labuschagne I., Welsh R., Nathan P.J., Wood A.G. Oxytocin enhances resting-state connectivity between amygdala and medial frontal cortex. Int. J. Neuropsychopharmacol. 2013, 16:255-260.
173. Stange J.P., Sylvia L.G., Magalhães P.V., da S., Frank E., Otto M.W., Miklowitz D.J., Deckersbach T. Extreme attributions predict transition from depression to mania or hypomania in bipolar disorder. J. Psychiatr. Res. 2013, 47:1329-1336.
174. Stavropoulos K.K., Carver L.J. Research review: social motivation and oxytocin in autism--implications for joint attention development and intervention. J. Child Psychol. Psychiatry 2013, 54:603-618.
175. Streit M., Wölwer W., Gaebel W. Facial-affect recognition and visual scanning behaviour in the course of schizophrenia. Schizophr. Res. 1997, 24:311-317.
176. Sweeney P.D., Anderson K., Bailey S. Attributional style in depression: a meta-analytic review. J. Personal. Soc. Psychol. 1986, 50:974-991.
177. Tollenaar M.S., Chatzimanoli M., van der Wee N.J., Putman P. Enhanced orienting of attention in response to emotional gaze cues after oxytocin administration in healthy young men. Psychoneuroendocrinology 2013, 38:1797-1802.
178. Tomasello M., Carpenter M., Call J., Behne T., Moll H. Understanding and sharing intentions: the origins of cultural cognition. Behav. Brain Sci. 2005, 28:675-691. (discussion 691-735).
179. Toomey R., Schuldberg D., Corrigan P., Green M.F. Nonverbal social perception and symptomatology in schizophrenia. Schizophr Res. 2002, 53:83-91.
180. Tracy A., Bauwens F., Martin F., Pardoen D., Mendlewicz J. Attributional style and depression: a controlled comparison of remitted unipolar and bipolar patients. Br. J. Clin. Psychol. 1992, 31:83-84.
181. Tseng H.H., Chen S.H., Liu C.M., Howes O., Huang Y.L., Hsieh M.H., Liu C.C., Shan J.C., Lin Y.T., Hwu H.G. Facial and prosodic emotion recognition deficits associate with specific clusters of psychotic symptoms in schizophrenia. PLoS One 2013, 8:e66571.
182. Turan T., Uysal C., Asdemir A., Kiliç E. oxytocin be a trait marker for bipolar disorder?. Psychoneuroendocrinology 2013, 38:2890-2896.
183. Uekermann J., Channon S., Lehmkämper C., Abdel-Hamid M., Vollmoeller W., Daum I. Executive function, mentalizing and humor in major depression. J. Int. Neuropsychol. Soc. 2008, 14:55-62.
184. van Hooren S., Versmissen D., Janssen I., Myin-Germeys I., À Campo J., Mengelers R., van Os J., Krabbendam L. Social cognition and neurocognition as independent domains in psychosis. Schizophr Res. 2008, 257-265.
185. Van Rheenen T.E., Rossell S.L. Phenomenological predictors of psychosocial function in bipolar disorder: is there evidence that social cognitive and emotion regulation abnormalities contribute?. Aust. N. Z. J. Psychiatry 2014, 48:26-35.
186. Ventura J., Wood R.C., Hellemann G.S. Symptom domains and neurocognitive functioning can help differentiate social cognitive processes in schizophrenia: a meta-analysis. Schizophr. Bull. 2013, 39:102-111.
187. Wang Y.G., Wang Y.Q., Chen S.L., Zhu C.Y., Wang K. Theory of mind disability in major depression with or without psychotic symptoms: a componential view. Psychiatry Res. 2008, 161:153-161.
188. Wang Y., Roberts D.L., Xu B., Cao R., Yan M., Jiang Q. Social cognition and interaction training for patients with stable schizophrenia in Chinese community settings. Psychiatry Res. 2013, 210:751-755.
189. Wilbertz G., Brakemeier E.-L., Zobel I., Härter M., Schramm E. Exploring preoperational features in chronic depression. J. Affect. Disord. 2010, 124:262-269.
190. Wolf F., Brüne M., Assion H.-J. Theory of mind and neurocognitive functioning in patients with bipolar disorder. Bipolar Disord. 2010, 12:657-666.
191. Wolkenstein L., Schonenberg M., Schirm E., Hautzinger M. I can see what you feel, but I can't deal with it: impaired theory of mind in depression. J. Affect. Disord. 2011, 132:104-111.
192. Wölwer W., Streit M., Polzer U., Gaebel W. Facial affect recognition in the course of schizophrenia. Eur. Arch. Psychiatry Clin. Neurosci. 1996, 246:165-170.
193. Zink C.F., Meyer-Lindenberg A. Human neuroimaging of oxytocin and vasopressin in social cognition. Horm. Behav. 2012, 61:400-409.