Can we achieve bone healing using the diamond concept without bone grafting for recalcitrant tibial nonunions?

Injury

Volumn 46, Issue 7, 2015, Pages 1383-1388

  Ollivier, M ^a   Gay, A M ^a   Cerlier, A ^a   Lunebourg, A ^a   Argenson, J N ^a   Parratte, S ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

Author keywords

BMP; Bone nonunion; Bone substitute; Recalcitrant; Tibia

Indexed keywords

CALCIUM PHOSPHATE; RECOMBINANT OSTEOGENIC PROTEIN 1; BIOMATERIAL; BMP7 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN; BONE PROSTHESIS; OSTEOGENIC PROTEIN 1;

ADULT; AGED; ANXIETY DISORDER; ARTICLE; BODY MASS; BONE GRAFT; BONE PROSTHESIS; BONE TRANSPLANTATION; CLINICAL ARTICLE; CRUTCH; DEBRIDEMENT; DECORTICATION; DEPRESSION; FEMALE; FOLLOW UP; FRACTURE EXTERNAL FIXATION; FRACTURE NONUNION; HUMAN; ILIAC CREST; MALE; OPEN FRACTURE; PATIENT SAFETY; PRIORITY JOURNAL; SALVAGE THERAPY; SELF CARE; SMOKING; STANDING; TIBIA FRACTURE; TREATMENT FAILURE; VISUAL ANALOG SCALE; WALKING; EPIDEMIOLOGY; FRACTURE HEALING; FRACTURES, UNUNITED; FRANCE; MIDDLE AGED; OSTEOSYNTHESIS; PATHOLOGY; PROCEDURES; THERAPEUTIC USE; TIBIAL FRACTURES; TREATMENT OUTCOME;

ADULT; AGED; BIOCOMPATIBLE MATERIALS; BONE MORPHOGENETIC PROTEIN 7; BONE MORPHOGENETIC PROTEINS; BONE SUBSTITUTES; BONE TRANSPLANTATION; CALCIUM PHOSPHATES; DEBRIDEMENT; FEMALE; FOLLOW-UP STUDIES; FRACTURE FIXATION, INTERNAL; FRACTURE HEALING; FRACTURES, UNUNITED; FRANCE; HUMANS; MALE; MIDDLE AGED; SALVAGE THERAPY; TIBIAL FRACTURES; TREATMENT OUTCOME;

EID: 84933179092     PISSN: 00201383     EISSN: 18790267     Source Type: Journal    
DOI: 10.1016/j.injury.2015.03.036     Document Type: Article

References (36)

1. C. Tzioupis, and P.V. Giannoudis Prevalence of long-bone non-unions Injury 38 Suppl. 2 2007 S3 S9
2. G.M. Calori, M. Phillips, S. Jeetle, L. Tagliabue, and P.V. Giannoudis Classification of non-union: need for a new scoring system? Injury 39 Suppl. 2 2008 S59 S63
3. E. Antonova, T.K. Le, R. Burge, and J. Mershon Tibia shaft fractures: costly burden of nonunions BMC Musculoskelet Disord 26 2013 14 42 http://dx.doi.org/10.1186/1471-2474-14-42
4. E.D. Arrington, W.J. Smith, H.G. Chambers, A.L. Bucknell, and N.A. Davino Complications of iliac crest bone graft harvesting Clin Orthop 329 1996 300 309
5. J.C. Fernyhough, J.J. Schimandle, M.C. Weigel, C.C. Edwards, and A.M. Levine Chronic donor site pain complicating bone graft harvesting from the posterior iliac crest for spinal fusion Spine 17 12 1992 1474 1480
6. P.V. Giannoudis, T.A. Einhorn, and D. Marsh Fracture healing: the diamond concept Injury 38 September (Suppl. 4) 2007 S3 S6 [review]
7. P.V. Giannoudis, T.A. Einhorn, G. Schmidmaier, and D. Marsh The diamond concept - open questions Injury 39 September (Suppl. 2) 2008 S5 S8 http://dx.doi.org/10.1016/S0020-1383(08)70010-X [review]
8. G.M. Calori, E. Mazza, M. Colombo, C. Ripamonti, and L. Tagliabue Treatment of long bone non-unions with polytherapy: indications and clinical results Injury 42 6 2011 587 590 http://dx.doi.org/10.1016/j.injury.2011.03.046 [Epub 2011 Apr 27, review]
9. L. Ambrosio, V. Guarino, V. Sanginario, P. Torricelli, M. Fini, M.P. Ginebra, J.A. Planell, and R. Giardino Injectable calcium-phosphate-based composites for skeletal bone treatments Biomed Mater 7 2 2012 024113 http://dx.doi.org/10.1088/1748-6041/7/2/024113 [Epub 2012 Mar 29]
10. J. Zhang, W. Liu, V. Schnitzler, F. Tancret, and J.M. Bouler Calcium phosphate cements for bone substitution: chemistry, handling and mechanical properties Acta Biomater 10 March (3) 2014 1035 1049 http://dx.doi.org/10.1016/j.actbio.2013.11.001 [Epub 2013 Nov 11]
11. T. Sakou Bone morphogenetic proteins: from basic studies to clinical approaches Bone 22 1998 591 603
12. A.H. Reddi Bone morphogenetic proteins: from basic science to clinical applications J Bone Joint Surg Am 83-A Suppl. 1 2001 1 6
13. S.D. Cook Preclinical and clinical evaluation of osteogenic protein-1 (BMP-7) in bony sites Orthopedics 22 1999 669 671
14. G.E. Friedlaender, C.R. Perry, J.D. Cole, S.D. Cook, G. Cierny, G.F. Muschler, and et al. Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions: a prospective, randomized clinical trial comparing rhOP-1 with fresh bone autograft J Bone Joint Surg Am 83 2001 151 158
15. R. Dimitriou, Z. Dahabreh, E. Katsoulis, S.J. Matthews, T. Branfoot, and P.V. Giannoudis Application of recombinant BMP-7 on persistent upper and lower limb non-unions Injury 36 Suppl. 4 2005 S51 S59
16. M. Ronga, F. Baldo, G. Zappalà, P. Cherubino, and BMP-7 Italian Observational Study (BIOS) Group Recombinant human bone morphogenetic protein-7 for treatment of long bone non-union: an observational, retrospective, non-randomized study of 105 patients Injury 37 September (Suppl. 3) 2006 S51 S56 Erratum in: Injury. 2007 Oct;38(10):1224
17. R. Capanna, L.B. Vangosa, P. Cherubino, F. Baldo, J. Ristiniemi, G. Kontakis, and P.V. Giannoudis Application of BMP-7 to tibial nonunions: a 3-year multicenter experience Injury 39 Suppl. 2 2008 S83 S90
18. S. Mathias, U.S. Nayak, and B. Isaacs Balance in elderly patients: the "get-up and go" test Arch Phys Med Rehabil 67 June (6) 1986 387 389
19. P.V. Giannoudis, N.K. Kanakaris, R. Dimitriou, I. Gill, V. Kolimarala, and R.J. Montgomery The synergistic effect of autograft and BMP-7 in the treatment of atrophic nonunions Clin Orthop Relat Res 467 December (12) 2009 3239 3248 http://dx.doi.org/10.1007/s11999-009-0846-2 [Epub 2009 Apr 24]
20. G.M. Calori, W. Albisetti, A. Agus, S. Iori, and L. Tagliabue Risk factors contributing to fracture nonunions Injury 38 Suppl. 2 2007 S11 S18
21. M.K. Sen, and T. Miclau Autologous iliac crest bone graft: should it still be the gold standard for treating nonunions? Injury 38 Suppl. 1 2007 S75 S80
22. W.G. De Long, T.A. Einhorn, K. Koval, M. McKee, W. Smith, R. Sanders, and et al. Bone grafts and bone graft substitutes in orthopaedic trauma surgery. A critical analysis J Bone Joint Surg Am 89 3 2007 649 658
23. A. Papathanasopoulos, and P.V. Giannoudis Biological considerations of mesenchymal stem cells and endothelial progenitor cells Injury 39 Suppl. 2 2008 S21 S32
24. I. Pountos, D. Corscadden, P. Emery, and P.V. Giannoudis Mesenchymal stem cell tissue engineering: techniques for isolation, expansion and application Injury 38 Suppl. 4 2007 S23 S33
25. G. Schmidmaier, P. Schwabe, C. Strobel, and B. Wildemann Carrier systems and application of growth factors in orthopaedics Injury 39 Suppl. 2 2008 S37 S43
26. T.W. Axelrad, S. Kakar, and T.A. Einhorn New technologies for the enhancement of skeletal repair Injury 38 Suppl. 1 2007 S49 S62
27. Kanakaris NK1, G.M. Calori, R. Verdonk, P. Burssens, P. De Biase, R. Capanna, L.B. Vangosa, P. Cherubino, F. Baldo, J. Ristiniemi, G. Kontakis, and P.V. Giannoudis Application of BMP-7 to tibial non-unions: a 3-year multicenter experience Injury 39 September (Suppl. 2) 2008 S83 S90 http://dx.doi.org/10.1016/S0020-1383(08)70019-6
28. M. Pecina, M. Haspl, M. Jelic, and S. Vukicevic Repair of a resistant tibial non-union with a recombinant bone morphogenetic protein-7 (rh-BMP-7) Int Orthop 27 2003 320 321
29. P.J. Harwood, and P.V. Giannoudis Application of bone morphogenetic proteins in orthopaedic practice: their efficacy and side effects Expert Opin Drug Saf 4 2005 75 89
30. P.V. Giannoudis, N.K. Kanakaris, and T.A. Einhorn Interaction of bone morphogenetic proteins with cells of the osteoclast lineage: review of the existing evidence Osteoporos Int 18 2007 1565 1581
31. M. Tall, D. Bonkoungou, M. Sawadogo, S.C. Da, M.F. Toe Bone and Joint Trauma Study Group (GETRAUM) Treatment of nonunion in neglected long bone shaft fractures by osteoperiosteal decortication Orthop Traumatol Surg Res 100 October (Suppl. 6) 2014 S299 S303 http://dx.doi.org/10.1016/j.otsr. 2014.07.005 [Epub 2014 Sep 2]
32. K.R. Garrison, S. Donell, J. Ryder, I. Shemilt, M. Mugford, I. Harvey, and F. Song Clinical effectiveness and cost-effectiveness of bone morphogenetic proteins in the non-healing of fractures and spinal fusion: a systematic review Health Technol Assess 11 30 2007 1 150 iii-iv
33. Z. Dahabreh, R. Dimitriou, and P.V. Giannoudis Health economics: a cost analysis of treatment of persistent fracture non-unions using bone morphogenetic protein-7 Injury 38 3 2007 371 377
34. D.N. Ramoutar, J. Rodrigues, C. Quah, C. Boulton, and C.G. Moran Judet decortication and compression plate fixation of long bone non-union: is bone graft necessary? Injury 42 December (12) 2011 1430 1434
35. T.J. Blokhuis, G.M. Calori, and G. Schmidmaier Autograft versus BMPs for the treatment of non-unions: what is the evidence? Injury 44 January (Suppl. 1) 2013 S40 S42 http://dx.doi.org/10.1016/S0020-1383(13)70009-3 [review]
36. G. Zimmermann, U. Muller, C. Loffler, A. Wentzensen, and A. Moghaddam Therapeutic outcome in tibial pseudarthrosis: bone morphogenetic protein 7 (BMP-7) versus autologous bone grafting for tibial fractures Unfallchirurg 110 2007 931 938 [in German]