메뉴 건너뛰기




Volumn 82, Issue 2, 1999, Pages 305-312

Functional reassessment of P16 variants using a transfection-based assay

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P16;

EID: 0033013780     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19990719)82:2<305::AID-IJC24>3.0.CO;2-Z     Document Type: Article
Times cited : (48)

References (37)
  • 1
    • 0029147732 scopus 로고
    • Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block phosphorylation of the cyclin-dependent kinases by CDK-activating kinase
    • APRELIKOVA O., XIONG, Y., and LIU, E.T., Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block phosphorylation of the cyclin-dependent kinases by CDK-activating kinase. J. biol. Chem., 270, 18195-18197 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 18195-18197
    • Aprelikova, O.1    Xiong, Y.2    Liu, E.T.3
  • 2
    • 0029091503 scopus 로고
    • Frequency of homozygous deletion at p16/CDKN2 in primary human tumours
    • CAIRNS, P. and 19 OTHERS, Frequency of homozygous deletion at p16/CDKN2 in primary human tumours. Nature (Genet.), 11, 210-212 (1995).
    • (1995) Nature (Genet.) , vol.11 , pp. 210-212
    • Cairns, P.1
  • 3
    • 0030786940 scopus 로고    scopus 로고
    • Restoration of CDKN2A into melanoma cells induces morphologic changes and reduction in growth rate but not anchorage-independent growth reversal
    • CASTELLANO, M., GABRIELLI, B.G., HUSSUSSIAN, C.J., DRACOPOLI, N.C. and HAYWARD, N.K., Restoration of CDKN2A into melanoma cells induces morphologic changes and reduction in growth rate but not anchorage-independent growth reversal. J. Invest. Dermatol., 109, 61-68 (1997a).
    • (1997) J. Invest. Dermatol. , vol.109 , pp. 61-68
    • Castellano, M.1    Gabrielli, B.G.2    Hussussian, C.J.3    Dracopoli, N.C.4    Hayward, N.K.5
  • 6
    • 0031771435 scopus 로고    scopus 로고
    • Aberrant cytoplasmic expression of the p16 protein in breast cancer is associated with accelerated tumour proliferation
    • EMIG, R., MAGENER, A., EHEMANN, V., V., MEYER, A., STILGENBAUER, F., VOLKMANN, M., WALLWIENER, D. and SINN, H-P., Aberrant cytoplasmic expression of the p16 protein in breast cancer is associated with accelerated tumour proliferation. Brit. J. Cancer, 78, 1661-1668 (1998).
    • (1998) Brit. J. Cancer , vol.78 , pp. 1661-1668
    • Emig, R.1    Magener, A.2    Ehemann, V.V.3    Meyer, A.4    Stilgenbauer, F.5    Volkmann, M.6    Wallwiener, D.7    Sinn, H.-P.8
  • 8
    • 0029947139 scopus 로고    scopus 로고
    • The current situation with regard to human melanoma and genetic inferences
    • HAYWARD, N.K., The current situation with regard to human melanoma and genetic inferences. Curr. Opin. Oncol., 8, 136-142 (1996).
    • (1996) Curr. Opin. Oncol. , vol.8 , pp. 136-142
    • Hayward, N.K.1
  • 11
    • 0028085975 scopus 로고
    • Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus
    • KAMB, A., SHATTUCK-EIDENS, D., ECLES, R., LIU, Q., GRUIS, N.A., ET AL., Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus. Nature (Genet), 8, 23-26 (1994b).
    • (1994) Nature (Genet) , vol.8 , pp. 23-26
    • Kamb, A.1    Shattuck-Eidens, D.2    Ecles, R.3    Liu, Q.4    Gruis, N.A.5
  • 12
    • 0029052951 scopus 로고
    • Tumor-derived p16 alleles encoding proteins defective in cell-cycle inhibition
    • KOH, J., ENDERS, G.H., DYNLACHT, B.D. and HARLOW, E., Tumor-derived p16 alleles encoding proteins defective in cell-cycle inhibition. Nature, 375, 506-510 (1995).
    • (1995) Nature , vol.375 , pp. 506-510
    • Koh, J.1    Enders, G.H.2    Dynlacht, B.D.3    Harlow, E.4
  • 19
    • 0028275733 scopus 로고
    • Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
    • NOBORI, T., MIURA, K., WU, D.J., LOIS, A., TAKABAYASHI, K. and CARSON, D. A., Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature (Lond. ), 368, 753-756 (1994).
    • (1994) Nature (Lond. ) , vol.368 , pp. 753-756
    • Nobori, T.1    Miura, K.2    Wu, D.J.3    Lois, A.4    Takabayashi, K.5    Carson, D.A.6
  • 21
    • 0029980941 scopus 로고    scopus 로고
    • Temperature sensitive mutants of p16/CDKN2 associated with familial melanoma
    • PARRY, D. and PETERS, G., Temperature sensitive mutants of p16/CDKN2 associated with familial melanoma. Mol. Cell Biol., 16, 3844-3852 (1996).
    • (1996) Mol. Cell Biol. , vol.16 , pp. 3844-3852
    • Parry, D.1    Peters, G.2
  • 22
    • 0030025518 scopus 로고    scopus 로고
    • Compilation of somatic mutations of the CDKN2 gene in human cancers: Non-random distribution of base substitutions
    • POLLOCK, P.M., PEARSON, J.V. and HAYWARD, N.K., Compilation of somatic mutations of the CDKN2 gene in human cancers: non-random distribution of base substitutions. Genes Chromosomes Cancer, 15, 77-88 (1996).
    • (1996) Genes Chromosomes Cancer , vol.15 , pp. 77-88
    • Pollock, P.M.1    Pearson, J.V.2    Hayward, N.K.3
  • 23
    • 7144229363 scopus 로고    scopus 로고
    • Haplotype analysis of 2 recurrent CDKN2A mutations in 10 melanoma families: Evidence for common founders and independent mutations
    • POLLOCK, P.M. and 12 OTHERS, Haplotype analysis of 2 recurrent CDKN2A mutations in 10 melanoma families: evidence for common founders and independent mutations. Hum. Mutation, 11, 424-431 (1998).
    • (1998) Hum. Mutation , vol.11 , pp. 424-431
    • Pollock, P.M.1
  • 24
    • 0029147195 scopus 로고
    • Evidence of UV induction of CDKN2 mutations in melanoma cell lines
    • POLLOCK, P.M., YU, F., QIU, L., PARSONS, P.G., and HAYWARD, N.K., Evidence of UV induction of CDKN2 mutations in melanoma cell lines. Oncogene, 11, 663-668 (1995).
    • (1995) Oncogene , vol.11 , pp. 663-668
    • Pollock, P.M.1    Yu, F.2    Qiu, L.3    Parsons, P.G.4    Hayward, N.K.5
  • 26
    • 0028971677 scopus 로고
    • p16 proteins from melanoma-prone families are deficient in binding to Cdk4
    • REYMOND, A. and BRENT, R., p16 proteins from melanoma-prone families are deficient in binding to Cdk4. Oncogene, 11, 1173-1178 (1995).
    • (1995) Oncogene , vol.11 , pp. 1173-1178
    • Reymond, A.1    Brent, R.2
  • 27
    • 0030614715 scopus 로고    scopus 로고
    • Kip1 coordinate their inhibitory interactions with cdk4 and cdk2
    • Kip1 coordinate their inhibitory interactions with cdk4 and cdk2. Genes Develop., 11, 492-503 (1997).
    • (1997) Genes Develop. , vol.11 , pp. 492-503
    • Reynisdóttir, I.1    Massagué, J.2
  • 29
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • SERRANO, M., HANNON, G.J. and BEACH, D., A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature (Lond.), 366, 704-707 (1993).
    • (1993) Nature (Lond.) , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 30
    • 0029665779 scopus 로고    scopus 로고
    • CDC37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilises CDK4
    • CDC37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilises CDK4. Genes Develop., 10, 1491 (1996).
    • (1996) Genes Develop. , vol.10 , pp. 1491
    • Stepanova, L.1    Leng, X.2    Parker, S.B.3    Harper, J.W.4
  • 32
    • 0028089946 scopus 로고
    • Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase)
    • TASSAN, J.P., SCHULTZ, S.J., BARTEK, J. and NIGG, E.A., Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase). J. Cell Biol., 127, 467-478 (1994).
    • (1994) J. Cell Biol. , vol.127 , pp. 467-478
    • Tassan, J.P.1    Schultz, S.J.2    Bartek, J.3    Nigg, E.A.4
  • 35
    • 0028862489 scopus 로고
    • Biochemical and mutagenic analysis of the melanoma tumour suppressor gene product/p16
    • WICK, S., DUBAY, M.M., IMANIL, I. and BRIZUELA, L., Biochemical and mutagenic analysis of the melanoma tumour suppressor gene product/p16. Oncogene, 11, 2013-2019 (1995).
    • (1995) Oncogene , vol.11 , pp. 2013-2019
    • Wick, S.1    Dubay, M.M.2    Imanil, I.3    Brizuela, L.4
  • 37
    • 0029802930 scopus 로고    scopus 로고
    • INK4 proteins encoded by tumour-derived alleles
    • INK4 proteins encoded by tumour-derived alleles. J. biol. Chem., 271, 28734-28737 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 28734-28737
    • Zhang, B.1    Peng, Z.-Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.