The FHA domain in DNA repair and checkpoint signaling

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 65, Issue , 2000, Pages 423-431

  Durocher, D ^a   Smerdon, S J ^b   Yaffe, M B ^b   Jackson, S P ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARABIDOPSIS; CELL CYCLE; CONFERENCE PAPER; DATA BASE; DNA DAMAGE; DNA REPAIR; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; REVIEW; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; ARTICLE; CELL CYCLE REGULATION; DNA DAMAGE CHECKPOINT; DNA DAMAGE RESPONSE; DNA STRUCTURE;

ARABIDOPSIS; SACCHAROMYCES CEREVISIAE;

TRANSCRIPTION FACTOR; FORKHEAD TRANSCRIPTION FACTOR; PHOSPHOPEPTIDE;

AMINO ACID SEQUENCE; ANIMAL; BINDING SITES; DNA REPAIR; HUMAN; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTORS;

EID: 0034437355     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.2000.65.423     Document Type: Conference Paper

References (43)

1. The Sad1/Rad53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast
2. Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome
3. The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: Linkage of double strand break repair to the cellular DNA damage response
4. Control of cell cycle arrest by the Mec1(sc)/Rad3(sp) DNA structure checkpoint pathway
5. Requirement of ATM-dependent phosphorylation of BRCA1 in the DNA damage response to double-strand breaks
6. The FHA domain is a modular phosphopeptide recognition motif
7. The molecular basis of FHA domain: Phosphopeptide binding specificity and implications for the evolution of phosphodependent signaling mechanisms
8. lck
9. MEC1-dependent phosphorylation of Rad9p in response to DNA damage
10. FHA domain boundaries of the Dun 1p and Rad53p cell cycle checkpoint kinases
11. The FHA domain: A putative nuclear signaling domain found in protein kinases and transcription factors
12. An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae
13. Forkhead-like transcription factors recruit Ndd1 to the chromatin of G2/M-specific promoters
14. Modular peptide-recognition domains in eukaryotic signaling
15. Measurement of the binding of tyrosyl phosphopeptides to Sh2 domains: A reappraisal
16. hCds1-mediated phosphorylation of BRCAI regulates the DNA damage response
17. Kinase interaction domain of kinase-associated protein phosphatase, a phosphoprotein-binding domain
18. Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity
19. High affinity binding of the Drosophila Numb phosphotyrosine binding domain to peptides containing a Gly Pro (p)Tyr motif
20. Structure and function of a new phosphopeptide-binding domain containing the FHA2 of Rad53
21. Sensing and responding to DNA damage
22. Function of WW domains as phosphoserine- or phosphothreonine-binding modules
23. Positional cloning of the gene for Nijmegen breakage syndrome
24. RAD9 and DNA polymerase epsilon form parallel sensory branches for transducing the DNA damage checkpoint signal in Saccharomyces cerevisiae
25. A checkpoint regulates the rate of progression through S phase in Saccharomyces cerevisiae in response to DNA damage
26. Protein-protein interactions define specificity in signal transduction
27. Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition
28. Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding
29. A single ataxia telangiectasia gene with a product similar to PI-3 kinase
30. Chfr defines a mitotic stress checkpoint that delays entry into metaphase
31. Comprehensive identification of cell cycle regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization
32. Interaction of a protein phosphatase with an Arabidopsis serine-threonine receptor kinase
33. Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint
34. Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways
35. Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome
36. The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage
37. Binding of a high-affinity phosphotyrosyl peptide to the Src SH2 domain crystal structures of the complexed and peptide-free forms
38. The RAD9 gene controls the cell-cycle response to DNA damage in Saccharomyces cerevisiae
39. Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
40. Signal transduction - Grabbing phosphoproteins
41. Structure and ligand recognition of the phosphotyrosine binding domain of Shc
42. Dun1 encodes a protein kinase that controls the DNA damage response in yeast
43. Two yeast forkhead genes regulate the cell cycle and pseudohyphal growth