Enhancing cancer targeting and anticancer activity by a stimulus-sensitive multifunctional polymer-drug conjugate

Journal of Controlled Release

Volumn 212, Issue , 2015, Pages 94-102

  Tu, Ying ^a   Zhu, Lin ^a  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

Cell penetrating peptide; Drug delivery; Matrix metalloproteinase 2; Multifunctional; Polymer drug conjugate; Tumor targeting

Indexed keywords

CELLS; CHEMOTHERAPY; COPOLYMERS; CYTOLOGY; DRUG DELIVERY; DRUG INTERACTIONS; DRUG THERAPY; ENZYME ACTIVITY; ENZYME INHIBITION; GLYCOPROTEINS; PEPTIDES; POLYMERS; SELF ASSEMBLY;

CELL-PENETRATING PEPTIDE; MATRIX METALLOPROTEINASE-2; MULTIFUNCTIONAL; POLYMER DRUGS; TUMOR TARGETING;

TUMORS;

CASPASE 3; CASPASE 7; CELL PENETRATING PEPTIDE; DOXORUBICIN; GELATINASE A; MACROGOL; MULTIDRUG RESISTANCE PROTEIN; ANTINEOPLASTIC AGENT; MACROGOL DERIVATIVE; MMP2 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER CHEMOTHERAPY; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG EFFICACY; DRUG PURIFICATION; DRUG RESPONSE; DRUG SOLUBILITY; DRUG SYNTHESIS; DRUG UPTAKE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INTERNALIZATION; MOLECULARLY TARGETED THERAPY; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; THIN LAYER CHROMATOGRAPHY; ZETA POTENTIAL; APOPTOSIS; CHEMISTRY; DRUG EFFECTS; METABOLISM; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; CELL-PENETRATING PEPTIDES; DOXORUBICIN; DRUG DELIVERY SYSTEMS; GENE PRODUCTS, TAT; HUMANS; MATRIX METALLOPROTEINASE 2; POLYETHYLENE GLYCOLS;

EID: 84932624003     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.06.024     Document Type: Article

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