Perivascular adipose tissue-derived adiponectin inhibits collar-induced carotid atherosclerosis by promoting macrophage autophagy

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Li, Changlong ^a,b   Wang, Zhijian ^a   Wang, Chunxiao ^b   Ma, Qian ^a   Zhao, Yingxin ^a,b  

^a BEIJING INSTITUTE OF HEART   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; BECLIN 1; MEMBRANE PROTEIN; PROTEIN KINASE B; PROTEIN LC3 I; PROTEIN P62; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG; ADIPOQ PROTEIN, MOUSE; APOLIPOPROTEIN E; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, MOUSE;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ARTICLE; AUTOPHAGY; CAROTID ARTERY; CAROTID ATHEROSCLEROSIS; CONTROLLED STUDY; DISEASE EXACERBATION; DOWN REGULATION; HYPOADIPONECTINEMIA; IN VITRO STUDY; KNOCKOUT MOUSE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PERIVASCULAR ADIPOSE TISSUE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN SECRETION; SIGNAL TRANSDUCTION; UPREGULATION; WILD TYPE; ANIMAL; ATHEROSCLEROSIS; DISEASE MODEL; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY; TRANSPLANTATION;

MUS;

ADIPONECTIN; ADIPOSE TISSUE; ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; AUTOPHAGY; CAROTID ARTERIES; DISEASE MODELS, ANIMAL; FORKHEAD BOX PROTEIN O3; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GENE KNOCKOUT TECHNIQUES; MACROPHAGES; MICE; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84932620088     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0124031     Document Type: Article

References (44)

1. Galkina E, Ley K. Immune and inflammatory mechanisms of atherosclerosis . Annual review of immunology. 2009; 27:165-197. doi: 10.1146/annurev.immunol.021908.132620 PMID: 19302038
2. Libby P, Ridker PM, Hansson GK. Progress and challenges in translating the biology of atherosclerosis. Nature. 2011; 473(7347):317-325. doi: 10.1038/nature10146 PMID: 21593864
3. Moore KJ, Tabas I. Macrophages in the pathogenesis of atherosclerosis. Cell. 2011; 145(3):341-355. doi: 10.1016/j.cell.2011.04.005 PMID: 21529710
4. Razani B, Feng C, Coleman T, Emanuel R, Wen H, Hwang S, et al. Autophagy links inflammasomes to atherosclerotic progression. Cell metabolism. 2012; 15(4):534-544. doi: 10.1016/j.cmet.2012.02.011 PMID: 22440612
5. Liao X, Sluimer JC, Wang Y, Subramanian M, Brown K, Pattison JS, et al. Macrophage autophagy plays a protective role in advanced atherosclerosis. Cell metabolism. 2012; 15(4):545-553. doi: 10.1016/j.cmet.2012.01.022 PMID: 22445600
6. Verheye S, Martinet W, Kockx MM, Knaapen MW, Salu K, Timmermans JP, et al. Selective clearance of macrophages in atherosclerotic plaques by autophagy. Journal of the American College of Cardiology. 2007; 49(6):706-715. PMID: 17291937
7. De Meyer I, Martinet W, Schrijvers DM, Timmermans JP, Bult H, De Meyer GR. Toll-like receptor 7 stimulation by imiquimod induces macrophage autophagy and inflammation in atherosclerotic plaques. Basic research in cardiology. 2012; 107(3):269. doi: 10.1007/s00395-012-0269-1 PMID: 22543675
8. Scherz-Shouval R, Elazar Z. Regulation of autophagy by ROS: physiology and pathology. Trends in biochemical sciences. 2011; 36(1):30-38. doi: 10.1016/j.tibs.2010.07.007 PMID: 20728362
9. Muller C, Salvayre R, Negre-Salvayre A, Vindis C. Oxidized LDLs trigger endoplasmic reticulum stress and autophagy: prevention by HDLs. Autophagy. 2011; 7(5):541-543. PMID: 21412049
10. Guo R, Zhang Y, Turdi S, Ren J. Adiponectin knockout accentuates high fat diet-induced obesity and cardiac dysfunction: role of autophagy. Biochimica et biophysica acta. 2013; 1832(8):1136-1148. doi: 10.1016/j.bbadis.2013.03.013 PMID: 23524376
11. Essick EE, Wilson RM, Pimentel DR, Shimano M, Baid S, Ouchi N, et al. Adiponectin modulates oxidative stress-induced autophagy in cardiomyocytes. PloS one. 2013; 8(7):e68697. doi: 10.1371/journal.pone.0068697 PMID: 23894332
12. Okamoto Y, Kihara S, Funahashi T, Matsuzawa Y, Libby P. Adiponectin: a key adipocytokine in metabolic syndrome. Clinical science (London, England: 1979). 2006; 110(3):267-278. PMID: 16464169
13. Okamoto Y, Folco EJ, Minami M, Wara AK, Feinberg MW, Sukhova GK, et al. Adiponectin inhibits the production of CXC receptor 3 chemokine ligands in macrophages and reduces T-lymphocyte recruitment in atherogenesis. Circulation research. 2008; 102(2):218-225. PMID: 17991878
14. Nawrocki AR, Hofmann SM, Teupser D, Basford JE, Durand JL, Jelicks LA, et al. Lack of association between adiponectin levels and atherosclerosis in mice. Arteriosclerosis, thrombosis, and vascular biology. 2010; 30(6):1159-1165. doi: 10.1161/ATVBAHA.109.195826 PMID: 20299691
15. Ouwens DM, Sell H, Greulich S, Eckel J. The role of epicardial and perivascular adipose tissue in the pathophysiology of cardiovascular disease. Journal of cellular and molecular medicine. 2010; 14 (9):2223-2234. doi: 10.1111/j.1582-4934.2010.01141.x PMID: 20716126
16. Miao CY, Li ZY. The role of perivascular adipose tissue in vascular smooth muscle cell growth. British journal of pharmacology. 2012; 165(3):643-658. doi: 10.1111/j.1476-5381.2011.01404.x PMID: 21470202
17. Iacobellis G, Gao YJ, Sharma AM. Do cardiac and perivascular adipose tissue play a role in atherosclerosis? Current diabetes reports. 2008; 8(1):20-24. PMID: 18366994
18. von der Thusen JH, van Berkel TJ, Biessen EA. Induction of rapid atherogenesis by perivascular carotid collar placement in apolipoprotein E-deficient and low-density lipoprotein receptor-deficient mice. Circulation. 2001; 103(8):1164-1170. PMID: 11222482
19. Barb D, Neuwirth A, Mantzoros CS, Balk SP. Adiponectin signals in prostate cancer cells through Akt to activate the mammalian target of rapamycin pathway. Endocrine-related cancer. 2007; 14(4):995-1005. PMID: 18045951
20. Tian Z, Miyata K, Tazume H, Sakaguchi H, Kadomatsu T, Horio E, et al. Perivascular adipose tissuesecreted angiopoietin-like protein 2 (Angptl2) accelerates neointimal hyperplasia after endovascular injury. Journal of molecular and cellular cardiology. 2013; 57:1-12. doi: 10.1016/j.yjmcc.2013.01.004 PMID: 23333801
21. Yang K, Zhang XJ, Cao LJ, Liu XH, Liu ZH, Wang XQ, et al. Toll-like receptor 4 mediates inflammatory cytokine secretion in smooth muscle cells induced by oxidized low-density lipoprotein. PloS one. 2014; 9(4):e95935. doi: 10.1371/journal.pone.0095935 PMID: 24755612
22. Sobiesiak M, Shumilina E, Lam RS, Wolbing F, Matzner N, Kaesler S, et al. Impaired mast cell activation in gene-targeted mice lacking the serum-and glucocorticoid-inducible kinase SGK1. Journal of immunology (Baltimore, Md: 1950). 2009; 183(7):4395-4402.
23. Li L, Cai XJ, Feng M, Rong YY, Zhang Y, Zhang M. Effect of adiponectin overexpression on stability of preexisting plaques by inducing prolyl-4-hydroxylase expression. Circulation journal: official journal of the Japanese Circulation Society. 2010; 74(3):552-559.
24. Maiuri MC, Grassia G, Platt AM, Carnuccio R, Ialenti A, Maffia P. Macrophage autophagy in atherosclerosis. Mediators of inflammation. 2013; 2013:584715. doi: 10.1155/2013/584715 PMID: 23401644
25. Chen S, Han Q, Wang X, Yang M, Zhang Z, Li P, et al. IBP-mediated suppression of autophagy promotes growth and metastasis of breast cancer cells via activating mTORC2/Akt/FOXO3a signaling pathway. Cell death & disease. 2013; 4:e842.
26. Farini D, La Sala G, Tedesco M, De Felici M. Chemoattractant action and molecular signaling pathways of Kit ligand on mouse primordial germ cells. Developmental biology. 2007; 306(2):572-583. PMID: 17467686
27. Huypens PR. Leptin and adiponectin regulate compensatory beta cell growth in accordance to overweight. Medical hypotheses. 2007; 68(5):1134-1137. PMID: 17098372
28. Shibata R, Sato K, Pimentel DR, Takemura Y, Kihara S, Ohashi K, et al. Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK-and COX-2-dependent mechanisms. Nature medicine. 2005; 11(10):1096-1103. PMID: 16155579
29. Essick EE, Ouchi N, Wilson RM, Ohashi K, Ghobrial J, Shibata R, et al. Adiponectin mediates cardioprotection in oxidative stress-induced cardiac myocyte remodeling. American journal of physiology Heart and circulatory physiology. 2011; 301(3):H984-993. doi: 10.1152/ajpheart.00428.2011 PMID: 21666115
30. Okamoto Y, Kihara S, Ouchi N, Nishida M, Arita Y, Kumada M, et al. Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation. 2002; 106(22):2767-2770. PMID: 12451000
31. Wang X, Pu H, Ma C, Jiang T, Wei Q, Zhang C, et al. Adiponectin abates atherosclerosis by reducing oxidative stress. Medical science monitor: international medical journal of experimental and clinical research. 2014; 20:1792-1800. doi: 10.12659/MSM.892299 PMID: 25275545
32. Tsubakio-Yamamoto K, Matsuura F, Koseki M, Oku H, Sandoval JC, Inagaki M, et al. Adiponectin prevents atherosclerosis by increasing cholesterol efflux from macrophages. Biochemical and biophysical research communications. 2008; 375(3):390-394. doi: 10.1016/j.bbrc.2008.08.009 PMID: 18703020
33. Ohman MK, Luo W, Wang H, Guo C, Abdallah W, Russo HM, et al. Perivascular visceral adipose tissue induces atherosclerosis in apolipoprotein E deficient mice. Atherosclerosis. 2011; 219(1):33-39. doi: 10.1016/j.atherosclerosis.2011.07.012 PMID: 21835408
34. Kawahito H, Yamada H, Irie D, Kato T, Akakabe Y, Kishida S, et al. Periaortic adipose tissue-specific activation of the renin-angiotensin system contributes to atherosclerosis development in uninephrectomized apoE-/-mice. American journal of physiology Heart and circulatory physiology. 2013; 305(5): H667-675. doi: 10.1152/ajpheart.00053.2013 PMID: 23812390
35. Li BH, Yin YW, Liu Y, Pi Y, Guo L, Cao XJ, et al. TRPV1 activation impedes foam cell formation by inducing autophagy in oxLDL-treated vascular smooth muscle cells. Cell death & disease. 2014; 5: e1182.
36. Peng N, Meng N, Wang S, Zhao F, Zhao J, Su L, et al. An activator of mTOR inhibits oxLDL-induced autophagy and apoptosis in vascular endothelial cells and restricts atherosclerosis in apolipoprotein E (-)/(-) mice. Scientific reports. 2014; 4:5519. doi: 10.1038/srep05519 PMID: 24980430
37. Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Molecular cell. 2010; 40(2):280-293. doi: 10.1016/j.molcel.2010.09.023 PMID: 20965422
38. Sarbassov DD, Ali SM, Sabatini DM. Growing roles for the mTOR pathway. Current opinion in cell biology. 2005; 17(6):596-603. PMID: 16226444
39. Inoki K, Li Y, Zhu T, Wu J, Guan KL. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nature cell biology. 2002; 4(9):648-657. PMID: 12172553
40. Ni HM, Du K, You M, Ding WX. Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity. The American journal of pathology. 2013; 183(6):1815-1825. doi: 10.1016/j.ajpath.2013.08.011 PMID: 24095927
41. Errafiy R, Aguado C, Ghislat G, Esteve JM, Gil A, Loutfi M, et al. PTEN increases autophagy and inhibits the ubiquitin-proteasome pathway in glioma cells independently of its lipid phosphatase activity. PloS one. 2013; 8(12):e83318. doi: 10.1371/journal.pone.0083318 PMID: 24349488
42. Strozyk E, Kulms D. The role of AKT/mTOR pathway in stress response to UV-irradiation: implication in skin carcinogenesis by regulation of apoptosis, autophagy and senescence. International journal of molecular sciences. 2013; 14(8):15260-15285. doi: 10.3390/ijms140815260 PMID: 23887651
43. Shi GD, OuYang YP, Shi JG, Liu Y, Yuan W, Jia LS. PTEN deletion prevents ischemic brain injury by activating the mTOR signaling pathway. Biochemical and biophysical research communications. 2011; 404(4):941-945. doi: 10.1016/j.bbrc.2010.12.085 PMID: 21185267
44. Levine B, Kroemer G. Autophagy in aging, disease and death: the true identity of a cell death impostor. Cell death and differentiation. 2009; 16(1):1-2. doi: 10.1038/cdd.2008.139 PMID: 19079285