Lactoferrin causes IgA and IgG2b isotype switching through betaglycan binding and activation of canonical TGF-β signaling

Mucosal Immunology

Volumn 8, Issue 4, 2015, Pages 906-917

  Jang, Y S ^a   Seo, G Y ^a   Lee, J M ^a   Seo, H Y ^a   Han, H J ^a   Kim, S J ^a   Jin, B R ^a   Kim, H J ^a   Park, S R ^b   Rhee, K J ^c   Kim, W S ^d   Kim, P H ^a  

^a Kangwon National University   (South Korea)

^b Konyang University College of Medicine   (South Korea)

^c Yonsei University Wonju   (South Korea)

^d Hankyong National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G2B; LACTOFERRIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 3; IMMUNOGLOBULIN G; IMMUNOLOGICAL ADJUVANT; PROTEIN BINDING; PROTEOGLYCAN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; IMMUNOGLOBULIN PRODUCTION; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ANIMAL; ANTIBODY PRODUCTION; BIOSYNTHESIS; DRUG EFFECTS; GENE REARRANGEMENT; IMMUNOLOGY; METABOLISM;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODY FORMATION; B-LYMPHOCYTES; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN G; LACTOFERRIN; MICE; PROTEIN BINDING; PROTEOGLYCANS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84932609932     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2014.121     Document Type: Article

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