Novel roles of GATA4/6 in the postnatal heart identified through temporally controlled, cardiomyocyte-specific gene inactivation by adeno-associated virus delivery of Cre recombinase

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Prendiville, Terence W ^a   Guo, Haidong ^a,b   Lin, Zhiqiang ^a   Zhou, Pingzhu ^a   Stevens, Sean M ^a   He, Aibin ^a,c   VanDusen, Nathan ^a   Chen, Jinghai ^a   Zhong, Li ^d   Wang, Da Zhi ^a,e   Gao, Guangping ^d   Pu, William T ^a,d  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c Tsinghua University   (China)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^e HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; PARVOVIRUS VECTOR; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 6; GATA4 PROTEIN, MOUSE; GATA6 PROTEIN, MOUSE; INTEGRASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIASTOLIC HEART FAILURE; GATA4 GENE; GATA6 GENE; GENE; GENE FUNCTION; GENE INACTIVATION; GENETIC RECOMBINATION; HEART MUSCLE CELL; LETHALITY; MOUSE; NEWBORN; NONHUMAN; PERINATAL PERIOD; PROMOTER REGION; SYSTOLIC HEART FAILURE; TNNT2 GENE; ANIMAL; CARDIAC MUSCLE CELL; DEPENDOPARVOVIRUS; GENE EXPRESSION REGULATION; GENE SILENCING; GENE VECTOR; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEART; METABOLISM; PHYSIOLOGY; TRANSGENIC MOUSE;

ADENO-ASSOCIATED VIRUS; ADENO-ASSOCIATED VIRUS 9;

ANIMALS; ANIMALS, NEWBORN; DEPENDOVIRUS; GATA4 TRANSCRIPTION FACTOR; GATA6 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE SILENCING; GENETIC VECTORS; HEART; HEART FAILURE, SYSTOLIC; INTEGRASES; MICE, TRANSGENIC; MYOCYTES, CARDIAC;

EID: 84932605032     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0128105     Document Type: Article

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