Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease

Nature Communications

Volumn 5, Issue , 2014, Pages

  He, Aibin ^a,b   Gu, Fei ^a   Hu, Yong ^a   Ma, Qing ^a   Yi Ye, Lillian ^a   Akiyama, Jennifer A ^c   Visel, Axel ^c,d,e   Pennacchio, Len A ^c,d   Pu, William T ^a,f  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b PEKING UNIVERSITY   (China)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d DOE JOINT GENOME INSTITUTE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR GATA 4; CHROMATIN; GATA4 PROTEIN, MOUSE; HISTONE; LUCIFERASE;

CARDIOVASCULAR SYSTEM; DISEASE; GENE EXPRESSION; HOMEOSTASIS; MAPPING;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CHROMATIN; CHRONIC STRESS; CONTROLLED STUDY; DEVELOPMENTAL STAGE; ENHANCER REGION; FETUS; FETUS HEART; GENE ACTIVATION; GENE EXPRESSION; GENE IDENTIFICATION; GENE MAPPING; HEART CONTRACTION; HEART DEVELOPMENT; HEART DISEASE; HEART HYPERTROPHY; HEART STRESS; HEART VENTRICLE HYPERTROPHY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN HOMEOSTASIS; RECEPTOR OCCUPANCY; VASCULARIZATION; ANIMAL; CARDIOMEGALY; CHROMATIN IMMUNOPRECIPITATION; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENETICS; HEART; HIGH THROUGHPUT SEQUENCING; METABOLISM; MORPHOGENESIS; NONPARAMETRIC TEST; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CARDIOMEGALY; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; ENHANCER ELEMENTS, GENETIC; GATA4 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HISTONES; LUCIFERASES; MICE; MICE, TRANSGENIC; MORPHOGENESIS; REAL-TIME POLYMERASE CHAIN REACTION; STATISTICS, NONPARAMETRIC;

EID: 84923327173     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5907     Document Type: Article

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