Reflectance confocal microscopy: Non-invasive distinction between actinic keratosis and squamous cell carcinoma

Journal of the European Academy of Dermatology and Venereology

Volumn 29, Issue 7, 2015, Pages 1302-1309

  Peppelman, M ^a   Nguyen, K P ^a   Hoogedoorn, L ^a   Van Erp, P E J ^a   Gerritsen, M J P ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACTINIC KERATOSIS; ADULT; AGED; ARTICLE; BLOOD VESSEL DIAMETER; CLINICAL ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DERMIS; FEMALE; HISTOPATHOLOGY; HUMAN; IN VIVO STUDY; INFLAMMATION; MALE; NON INVASIVE PROCEDURE; PRIORITY JOURNAL; REFLECTANCE CONFOCAL MICROSCOPY; SKIN; SKIN BIOPSY; SPINOUS LAYER; SQUAMOUS CELL CARCINOMA; STRATUM GRANULOSUM; STRATUM SPINOSUM; VERY ELDERLY; BIOPSY; CARCINOMA, SQUAMOUS CELL; DIFFERENTIAL DIAGNOSIS; KERATOSIS, ACTINIC; MIDDLE AGED; PATHOLOGY; PROCEDURES; SKIN NEOPLASMS;

AGED; AGED, 80 AND OVER; BIOPSY; CARCINOMA, SQUAMOUS CELL; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; KERATOSIS, ACTINIC; MALE; MICROSCOPY, CONFOCAL; MIDDLE AGED; SKIN; SKIN NEOPLASMS;

EID: 84932603053     PISSN: 09269959     EISSN: 14683083     Source Type: Journal    
DOI: 10.1111/jdv.12806     Document Type: Article

References (44)

1. Rubin AI, Chen EH, Ratner D,. Basal-cell carcinoma. N Engl J Med 2005; 353: 2262-2269. Epub 2005/11/25.
2. Ridky TW,. Nonmelanoma skin cancer. J Am Acad Dermatol 2007; 57: 484-501. Epub 2007/05/22.
3. Lomas A, Leonardi-Bee J, Bath-Hextall F,. A systematic review of worldwide incidence of nonmelanoma skin cancer. Br J Dermatol 2012; 166: 1069-1080. Epub 2012/01/19.
4. Yanofsky VR, Mercer SE, Phelps RG,. Histopathological variants of cutaneous squamous cell carcinoma: a review. J Skin Cancer. 2011; 2011: 210813.
5. Callen JP, Bickers DR, Moy RL,. Actinic keratoses. J Am Acad Dermatol 1997; 36: 650-653. Epub 1997/04/01.
6. Marks R, Rennie G, Selwood TS,. Malignant transformation of solar keratoses to squamous cell carcinoma. Lancet 1988; 1: 795-797. Epub 1988/04/09.
7. Quaedvlieg PJ, Tirsi E, Thissen MR, Krekels GA,. Actinic keratosis: how to differentiate the good from the bad ones? Eur J Dermatol. 2006; 16: 335-339. Epub 2006/08/29.
8. Ehrig T, Cockerell C, Piacquadio D, Dromgoole S,. Actinic keratoses and the incidence of occult squamous cell carcinoma: a clinical-histopathologic correlation. Dermatol Surg 2006; 32: 1261-1265. Epub 2006/10/13.
9. Rishpon A, Kim N, Scope A, et al,. Reflectance confocal microscopy criteria for squamous cell carcinomas and actinic keratoses. Arch Dermatol 2009; 145: 766-772. Epub 2009/07/22.
10. Rosendahl C, Cameron A, Argenziano G, Zalaudek I, Tschandl P, Kittler H,. Dermoscopy of squamous cell carcinoma and keratoacanthoma. Arch Dermatol 2012; 148: 1386-1392. Epub 2012/09/19.
11. Peris K, Micantonio T, Piccolo D, Fargnoli MC,. Dermoscopic features of actinic keratosis. J Dtsch Dermatol Ges. 2007; 5: 970-976. Epub 2007/10/03.
12. Calzavara-Pinton P, Longo C, Venturini M, Sala R, Pellacani G,. Reflectance confocal microscopy for in vivo skin imaging. Photochem Photobiol 2008; 84: 1421-1430. Epub 2008/12/11.
13. Gonzalez S,. Confocal reflectance microscopy in dermatology: promise and reality of non-invasive diagnosis and monitoring. Actas Dermosifiliogr 2009; 100 (Suppl 2): 59-69. Epub 2010/01/26.
14. Langley RG, Burton E, Walsh N, Propperova I, Murray SJ,. In vivo confocal scanning laser microscopy of benign lentigines: comparison to conventional histology and in vivo characteristics of lentigo maligna. J Am Acad Dermatol 2006; 55: 88-97. Epub 2006/06/20.
15. Gonzalez S, Gonzalez E, White WM, Rajadhyaksha M, Anderson RR,. Allergic contact dermatitis: correlation of in vivo confocal imaging to routine histology. J Am Acad Dermatol 1999; 40: 708-713. Epub 1999/05/13.
16. Gonzalez S, Rajadhyaksha M, Rubinstein G, Anderson RR,. Characterization of psoriasis in vivo by reflectance confocal microscopy. J Med 1999; 30: 337-356. Epub 2000/06/14.
17. Peppelman M, Wolberink EA, Blokx WA, van de Kerkhof PC, van Erp PE, Gerritsen MJ,. In vivo diagnosis of basal cell carcinoma subtype by reflectance confocal microscopy. Dermatology 2013; 227: 255-262. Epub 2013/10/26.
18. Gonzalez S, Tannous Z,. Real-time, in vivo confocal reflectance microscopy of basal cell carcinoma. J Am Acad Dermatol 2002; 47: 869-874. Epub 2002/11/27.
19. Nori S, Rius-Diaz F, Cuevas J, et al,. Sensitivity and specificity of reflectance-mode confocal microscopy for in vivo diagnosis of basal cell carcinoma: a multicenter study. J Am Acad Dermatol 2004; 51: 923-930. Epub 2004/12/08.
20. Sauermann K, Gambichler T, Wilmert M, et al,. Investigation of basal cell carcinoma [Correction of Carcionoma] by confocal laser scanning microscopy in vivo. Skin Res Technol 2002; 8: 141-147. Epub 2002/09/19.
21. Wolberink EA, van Erp PE, de Boer-van Huizen RT, de van Kerkhof PC, Gerritsen MJ,. Reflectance confocal microscopy: an effective tool for monitoring ultraviolet B phototherapy in psoriasis. Br J Dermatol. 2012; 167: 396-403. Epub 2012/04/20.
22. Longo C, Casari A, Pepe P, et al,. Confocal microscopy insights into the treatment and cellular immune response of basal cell carcinoma to photodynamic therapy. Dermatology 2012; 225: 264-270. Epub 2012/12/22.
23. Guitera P, Menzies SW, Longo C, Cesinaro AM, Scolyer RA, Pellacani G,. In vivo confocal microscopy for diagnosis of melanoma and basal cell carcinoma using a two-step method: analysis of 710 consecutive clinically equivocal cases. J Invest Dermatol 2012; 132: 2386-2394. Epub 2012/06/22.
24. Langley RG, Walsh N, Sutherland AE, et al,. The diagnostic accuracy of in vivo confocal scanning laser microscopy compared to dermoscopy of benign and malignant melanocytic lesions: a prospective study. Dermatology 2007; 215: 365-372. Epub 2007/10/04.
25. Wolberink EA, van Erp PE, Teussink MM, van de Kerkhof PC, Gerritsen MJ,. Cellular features of psoriatic skin: imaging and quantification using in vivo reflectance confocal microscopy. Cytometry Part B, Clinical Cytometry 2011; 80: 141-149. Epub 2011/04/27.
26. Horn M, Gerger A, Ahlgrimm-Siess V, et al,. Discrimination of actinic keratoses from normal skin with reflectance mode confocal microscopy. Dermatol Surg 2008; 34: 620-625. Epub 2008/04/24.
27. Ulrich M, Forschner T, Rowert-Huber J, et al,. Differentiation between actinic keratoses and disseminated superficial actinic porokeratoses with reflectance confocal microscopy. Br J Dermatol 2007; 156 (Suppl 3): 47-52. Epub 2007/05/10.
28. Aghassi D, Anderson RR, Gonzalez S,. Confocal laser microscopic imaging of actinic keratoses in vivo: a preliminary report. J Am Acad Dermatol 2000; 43: 42-48. Epub 2000/06/23.
29. Ahlgrimm-Siess V, Cao T, Oliviero M, Hofmann-Wellenhof R, Rabinovitz HS, Scope A,. The vasculature of nonmelanocytic skin tumors on reflectance confocal microscopy: vascular features of squamous cell carcinoma in situ. Arch Dermatol. 2011; 147: 264. Epub 2011/02/23.
30. Peppelman M, Wolberink EA, Koopman RJ, van Erp PE, Gerritsen MJ,. In vivo reflectance confocal microscopy: a useful tool to select the location of a punch biopsy in a large, clinically indistinctive lesion. Case Reports Dermatol 2013; 5: 129-132. Epub 2013/05/21.
31. Richtig E, Ahlgrimm-Siess V, Koller S, et al,. Follow-up of actinic keratoses after shave biopsy by in-vivo reflectance confocal microscopy-a pilot study. J Eur Acad Dermatol Venereol 2010; 24: 293-298. Epub 2009/09/08.
32. Ulrich M, Kanitakis J, Gonzalez S, Lange-Asschenfeldt S, Stockfleth E, Roewert-Huber J,. Evaluation of bowen disease by in vivo reflectance confocal microscopy. Br J Dermatol 2012; 166: 451-453. Epub 2011/08/10.
33. Ulrich M, Lange-Asschenfeldt S, Gonzalez S,. In vivo reflectance confocal microscopy for early diagnosis of nonmelanoma skin cancer. Actas Dermosifiliogr 2012; 103: 784-789. Epub 2012/05/18.
34. Ulrich M, Maltusch A, Rowert-Huber J, et al,. Actinic keratoses: non-invasive diagnosis for field cancerisation. Br J Dermatol 2007; 156 (Suppl 3): 13-17. Epub 2007/05/10.
35. Wurm EM, Curchin CE, Lambie D, Longo C, Pellacani G, Soyer HP,. Confocal features of equivocal facial lesions on severely sun-damaged skin: four case studies with dermatoscopic, confocal, and histopathologic correlation. J Am Acad Dermatol 2012; 66: 463-473. Epub 2011/10/08.
36. Ulrich M, Krueger-Corcoran D, Roewert-Huber J, Sterry W, Stockfleth E, Astner S,. Reflectance confocal microscopy for noninvasive monitoring of therapy and detection of subclinical actinic keratoses. Dermatology 2010; 220: 15-24. Epub 2009/11/13.
37. Ulrich M, Maltusch A, Rius-Diaz F, et al,. Clinical applicability of in vivo reflectance confocal microscopy for the diagnosis of actinic keratoses. Dermatol Surg 2008; 34: 610-619. Epub 2008/02/12.
38. Rajadhyaksha M, Gonzalez S, Zavislan JM, Anderson RR, Webb RH,. In vivo confocal scanning laser microscopy of human skin II: advances in instrumentation and comparison with histology. J Invest Dermatol 1999; 113: 293-303. Epub 1999/09/01.
39. Rajadhyaksha M, Grossman M, Esterowitz D, Webb RH, Anderson RR,. In vivo confocal scanning laser microscopy of human skin: melanin provides strong contrast. J Invest Dermatol 1995; 104: 946-952. Epub 1995/06/01.
40. Braga JC, Scope A, Klaz I, et al,. The significance of reflectance confocal microscopy in the assessment of solitary pink skin lesions. J Am Acad Dermatol 2009; 61: 230-241. Epub 2009/04/29.
41. Skobe M, Rockwell P, Goldstein N, Vosseler S, Fusenig NE,. Halting angiogenesis suppresses carcinoma cell invasion. Nat Med 1997; 3: 1222-1227. Epub 1997/11/14.
42. Cox NH, Eedy DJ, Morton CA, Therapy G, Audit Subcommittee BAoD. Guidelines for management of bowen's disease: 2006 update. Br J Dermatol 2007; 156: 11-21. Epub 2007/01/04.
43. Rao BK, Mateus R, Wassef C, Pellacani G,. In vivo confocal microscopy in clinical practice: comparison of bedside diagnostic accuracy of a trained physician and distant diagnosis of an expert reader. J Am Acad Dermatol 2013; 69: e295-e300. Epub 2013/09/17.
44. Fraga-Braghiroli N, Stephens A, Oliviero M, Rabinovitz H, Scope A,. Small brown circles: an important diagnostic clue for pigmented squamous cell carcinoma. J Am Acad Dermatol 2013; 69: e161-e163. Epub 2013/09/17.