In vivo confocal microscopy for diagnosis of melanoma and basal cell carcinoma using a two-step method: Analysis of 710 consecutive clinically equivocal cases

Journal of Investigative Dermatology

Volumn 132, Issue 10, 2012, Pages 2386-2394

  Guitera, Pascale ^a,b   Menzies, Scott W ^a   Longo, Caterina ^c   Cesinaro, Anna M ^d   Scolyer, Richard A ^a,b   Pellacani, Giovanni ^c,d  

^a ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^b MELANOMA INSTITUTE AUSTRALIA   (Australia)

^c S MARIA NUOVA HOSPITAL   (Italy)

^d UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHM; ARTICLE; BASAL CELL CARCINOMA; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC ERROR; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MELANOMA; PRIORITY JOURNAL; REFLECTANCE CONFOCAL MICROSCOPY; SENSITIVITY AND SPECIFICITY; SKIN DEFECT; TELANGIECTASIA;

EID: 84866374621     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2012.172     Document Type: Article

References (18)

1. Agero AL, Busam KJ, Benvenuto-Andrade C et al. (2006) Reflectance confocal microscopy of pigmented basal cell carcinoma. J Am Acad Dermatol 54:638-43
2. Gerger A, Koller S, Kern T et al. (2005) Diagnostic applicability of in vivo confocal laser scanning microscopy in melanocytic skin tumors. J Invest Dermatol 124:493-8 (Pubitemid 40381570)
3. Gonzalez S, Tannous Z (2002) Real-time, in vivo confocal reflectance microscopy of basal cell carcinoma. J Am Acad Dermatol 47:869-74 (Pubitemid 35403045)
4. Guitera P, Pellacani G, Longo C et al. (2009) In vivo reflectance confocal microscopy enhances secondary evaluation of melanocytic lesions. J Invest Dermatol 129:131-8
5. Langley RG, Burton E, Walsh N et al. (2006) In vivo confocal scanning laser microscopy of benign lentigines: comparison to conventional histology and in vivo characteristics of lentigo maligna. J Am Acad Dermatol 55:88-97 (Pubitemid 43867044)
6. Langley RG, Rajadhyaksha M, Dwyer PJ et al. (2001) Confocal scanning laser microscopy of benign and malignant melanocytic skin lesions in vivo. J Am Acad Dermatol 45:365-76 (Pubitemid 32800491)
7. Langley RG, Walsh N, Sutherland AE et al. (2007) The diagnostic accuracy of in vivo confocal scanning laser microscopy compared to dermoscopy of benign and malignant melanocytic lesions: a prospective study. Dermatology 215:365-72 (Pubitemid 47519273)
8. McNeil BJ, Hanley JA (1984) Statistical approaches to the analysis of receiver operating characteristic (ROC) curves. Med Decis Making 4:137-50 (Pubitemid 14001462)
9. Nori S, Rius-Diaz F, Cuevas J et al. (2004) Sensitivity and specificity of reflectance-mode confocal microscopy for in vivo diagnosis of basal cell carcinoma: a multicenter study. J Am Acad Dermatol 51:923-30 (Pubitemid 39593007)
10. Pellacani G, Cesinaro AM, Seidenari S (2005) Reflectance-mode confocal microscopy of pigmented skin lesions-improvement in melanoma diagnostic specificity. J Am Acad Dermatol 53:979-85 (Pubitemid 41677323)
11. Pellacani G, Guitera P, Longo C et al. (2007) The impact of in vivo reflectance confocal microscopy for the diagnostic accuracy of melanoma and equivocal melanocytic lesions. J Invest Dermatol 127:2759-65 (Pubitemid 350134828)
12. Pellacani G, Longo C, Ferrara G et al. (2009) Spitz nevi: in vivo confocal microscopic features, dermatoscopic aspects, histopathologic correlates, and diagnostic significance. J Am Acad Dermatol 60:236-47
13. Scope A, Benven-Andrade C, Agero AL et al. (2007) In vivo reflectance confocal microscopy imaging of melanocytic skin lesions: consensus terminology glossary and illustrative images. J Am Acad Dermatol 57:644-58 (Pubitemid 47384934)
14. Segura S, Puig S, Carrera C et al. (2007) Dendritic cells in pigmented basal cell carcinoma: a relevant finding by reflectance-mode confocal microscopy. Arch Dermatol 143:883-6 (Pubitemid 47076486)
15. Segura S, Pellacani G, Puig S et al. (2008) In vivo microscopic features of nodular melanomas:dermoscopy, confocal microscopy, and histopathologic correlates. Arch Dermatol 144:1311-20
16. Segura S, Puig S, Carrera C et al. (2009) Development of a two-step method for the diagnosis of melanoma by reflectance confocal microscopy. J Am Acad Dermatol 61:216-29
17. Ulrich M, Roewert-Huber J, González S et al. (2011) Peritumoral clefting in basal cell carcinoma: correlation of in vivo reflectance confocal microscopy and routine histology. J Cutan Pathol 38:190-5
18. Zalaudek I, Kreusch J, Giacomel J et al. (2010) How to diagnose nonpigmented skin tumors: a review of vascular structures seen with dermoscopy: part II. Nonmelanocytic skin tumors. J Am Acad Dermatol 63:377-86