Effect of ginkgo biloba extract on lead-induced oxidative stress in different regions of rat brain

Journal of Environmental Pathology, Toxicology and Oncology

Volumn 34, Issue 2, 2015, Pages 161-173

  Yallapragada, Prabhakara Rao ^a   Velaga, Manoj Kumar ^a  

^a ANDHRA UNIVERSITY   (India)

Author keywords

Ginkgo biloba; Lead toxicity; Oxidative stress; Rat brain; Reactive oxygen species

Indexed keywords

CARBONYL DERIVATIVE; CATALASE; GINKGO BILOBA EXTRACT; LEAD; PROTEIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; ANTIOXIDANT; PLANT EXTRACT; POLLUTANT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN STEM; BRAIN TISSUE; BRAIN TOXICITY; CEREBELLUM; CONTROLLED STUDY; ENZYME ACTIVITY; FRONTAL CORTEX; HIPPOCAMPUS; LEAD INDUCED OXIDATIVE STRESS; LEAD POISONING; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; ANIMAL; BRAIN; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; GINKGO BILOBA; MALE; METABOLISM; POLLUTANT; TOXICITY; WISTAR RAT;

GINKGO BILOBA; RATTUS; RATTUS NORVEGICUS;

ANIMALS; ANTIOXIDANTS; BRAIN; ENVIRONMENTAL POLLUTANTS; GINKGO BILOBA; LEAD; MALE; OXIDATIVE STRESS; PLANT EXTRACTS; RATS; RATS, WISTAR;

EID: 84932158892     PISSN: 07318898     EISSN: None     Source Type: Journal    
DOI: 10.1615/JEnvironPatholToxicolOncol.2015013095     Document Type: Article

References (68)

1. Flora G, Gupta D, Tiwari A. Toxicity of lead: a review with recent updates. Interd Toxicol. 2012;5(2): 47-58
2. van der Kuijp TJ, Huang L, Cherry CR. Health hazards of China’s lead-acid battery industry: a review of its market drivers, production processes, and health impacts. Environ Health. 2013;12:61.
3. Chen A, Dietrich KN, Huo X, Ho S. Developmental neurotoxicants in E-waste: emerging health concern. Env Health Persp. 2011;119(4):431-8
4. Kalia K, Flora SJ. Strategies for safe and effective therapeutic measures for chronic arsenic and lead poisoning. J Occup Health. 2005;47:1-21
5. Liu J, Lewis G. Environmental toxicity and poor cognitive outcomes in children and adults. J Environ Health. 2014;76(6):130-8
6. Bakulski KM, Rozek LS, Dolinoy DC, Paulson HL, Hu H. Alzheimer’s disease and environmental exposure to lead: the epidemiologic evidence and potential role of epigenetics. Curr Alzheimer Res. 2012;9(5):563-73
7. Flora SJ, Flora G, Saxena G, Mishra M. Arsenic and lead induced free radical generation and their reversibility following chelation. Cell Mol Biol. 2007;53:26-47
8. Adonaylo VN, Oteiza PI. Lead intoxication, antioxidant defenses and oxidative stress in rat brain. Toxicol. 1999;135(3):77-85
9. Bokara KK, Brown E, McCormick R, Yallapragada PR, Sharada R, Rajanna B. Lead induced increase in antioxidant enzymes and lipid peroxidation products in developing rat brain. Biometals. 2008;21:9-16
10. Fracasso ME, Perbillini L, Solda S, Talamini G, Francescheni P. Lead-induced DNA strand breaks in lymphocytes of exposed workers: role of reactive oxygen species and protein kinase-C. Mutat Res. 2002;515: 159-69
11. Kiran Kumar B, Prabhakara Rao Y, Noble T, Weddington K, McDowell VP, Rajanna S, Bettaiya R. Lead-induced alteration of apoptotic proteins in different regions of adult rat brain. Toxicol Lett. 2009;184:56-60
12. Bokara KK, Blaylock L, Denise SB, Bettaiya R, Rajanna S, Yallapragada PR. Influence of lead acetate on glutathione and its related enzymes in different regions of rat brain. J Appl Toxicol. 2009;29:452-8
13. Sharma V, Sharma A, Kansal L. The effect of oral administration of Allium sativum on lead nitrate-induced toxicity in male mice. Food Chem Toxicol. 2010;48: 928-36
14. Dairam A, Limson JL, Wakins GM, Antunes E, Daya S. Curminoids, curcumin and demethoxy curcumin reduce lead-induced memory deficits in male Wistar rats. J Agri Food Chem. 2010;55:1039-44
15. Mehana EE, Meki ARMA, Fazili KM. Ameliorated effects of green tea on lead-induced liver toxicity in rats. Exp Toxicol Pathol. 2012;291-5
16. Li C, Pan Z, Xu T, Zhang C, Wu Q, Niu Y. Puerarin induces the upregulation of glutathione levels and nuclear translocation of Nrf2 through P13K/Akt/GSK-3β signaling events in PC12 cells exposed to lead. Neurotoxicol Teratol. 2014;46:1-9
17. Liu CM, Ma JQ, Sun YZ. Quercetin protects the rat kidney against oxidative stress-mediated DNA damage and apoptosis induced by lead. Environ Toxicol Pharmacol. 2010;30:264-71
18. Zhang J, Yan C, Wang S, Hou Y, Xue G, Zhang L. Chrysophanol attenuates lead exposure-induced injury to hippocampal neurons in neonatal mice. Neural Regen Res. 2014; 9(9):924-930
19. Wang Y, Wang S, Cui W, He J, Wang Z, Yang X. Olive leaf extract inhibits lead poisoning-induced brain injury. Neural Regen Res. 2013;8(22):2021-9
20. Lalitha Kumari V, Muralidhara. Ameliorative effects of ferulic acid against lead acetate-induced oxidative stress, mitochondrial dysfunctions and toxicity in prepubertal rat brain. Neurochem Res. 2014;39(12):2501-15
21. Hosseini A, Sharifi AM, Abdollahi M, Najafi R, Baeeri M, Ravegan S, Cheshmehnour J, Hassani S, Bayrami Z, Safa M. Cerium and yttrium oxide nanoparticles against lead-induced oxidative stress and apoptosis in rat hippocampus. Biol Trace Elem Res. 2015;164(1): 80-9
22. Singh B, Kaur P, Gopichand C, Singh BD, Ahuja PS. Biology and chemistry of Ginkgo biloba. Fitoterapia. 2008;79:401-18
23. Chan PC, Xia Q, Fu PP. Ginkgo biloba leave extract: Biological, medicinal, and toxicological effects. J Environ Sci Health C. Environ Carcinog Ecotoxicol Rev. 2007;25(3):211-44
24. Ude C, Schubert-Zsilavecz M, Wurglics M. Ginkgo biloba extracts: a review of the pharmacokinetics of the active ingredients. Clin Pharmacokinet. 2013;52(9):727-49
25. van Beek TA, Montoro P. Chemical analysis and quality control of Ginkgo biloba leaves, extracts and phytopharmaceuticals. J Chromatogr. 2009;12:2002-32
26. Liao HJ, Zheng YF, Li HY, Peng GP. Two new ginkogolides from leaves of Ginkgo biloba. Planta Med. 2011;77:1818-21
27. Diamond BJ, Shiflett SC, Feiwel N, Mateis RJ, Noskin O, Richards JA, Schoenberger NE. Ginkgo biloba extract: mechanisms and clinical indications. Arch Phys Med Rehabil. 2000;81(5):668-78
28. Gertz HJ, Kieter M. Review about Ginkgo biloba special extract EGB 761 (Ginkgo). Curr Pharma Des. 2004;10(3):261-4
29. Mohanta TK, Tambili Y, Zubaidha PK. Phytochemical and medicinal importance of Ginkgo biloba L. Nat Prod Res. 2014;28(10):746-52
30. Tan MS, Yu JT, Tan CC, Wang HF, Meng XF, Wang C, Jiang T, Zhu XC, Tan L. Efficacy and adverse effects of Ginkgo biloba for cognitive impairment and dementia: a systematic review and meta-analysis. J Alzheimer’s Disease. 2015;43:589-603
31. Tanaka K, Galduroz RF, Gobbi LT, Galduroz JC. Ginkgo biloba extract in an animal model of Parkinson’s disease: a systematic review. Curr Neuropharmacol. 2013;11(4):430-5
32. Gong QH, Wu Q, Huang XN, Sun AS, Shi JS. Protective effects of Ginkgo biloba leaf extract on aluminum-induced brain dysfunction in rat. Life Sci. 2005;77(2):140-8
33. Gong QH, Wu Q, Huang XN, Sun AS, Nie J, Shi JS. Protective effect of Ginkgo biloba leaf extract on learning and memory of deficit induced by aluminum in model rats. Chin J Integra Med. 2006;12(1):37-41
34. Abd-Elhady RM, Elsheikh AM, Khalifa AE. Ani-amnesic properties of Ginkgo biloba extract on impaired memory function induced by aluminum in rats. Int J Dev Neurosci. 2013;31(7):598-607
35. Sener G, Sehirli O, Tozan A, Velioglu-Ovunc A, Gedik N, Omurtag GZ. Ginkgo biloba extract protects against mercury (II)-induced oxidative tissue damage in rats. Food Chem Toxicol. 2007;45(4):543-55
36. Tunali-Akbay T, Sener G, Salvarli H, Sehirli O, Yarat A. Protective effects of Ginkgo biloba extract against mercury (II)-induced cardiovascular oxidative damage in rats. Phytother Res. 2007;21(1):26-31
37. de Souza Predes F, Monteiro JC, Matta SL, Garcia MC, Dolder H. Testicular histomorphometry and ultra structure of rats treated with cadmium and Ginkgo biloba. Biol Trace Elem Res. 2011;140(3):330-341
38. Otani M, Chatterjee SS, Gabard B, Kreutzberg GW. Effect of an extract of Ginkgo biloba on triethyltin-induced cerebral edema. Acta Neuropathol. 1986;69(1-2);54-65
39. Kaur S, Chhabra R, Nehru B. Ginkgo biloba extract attenuates hippocampal neuronal loss and cognitive dysfunction resulting from trimethyltin in mice. Phytomed. 2013;20(2):178-86
40. Yapar K, Cavusoglu K, Oruc E, Yalcin E. Protective role of Ginkgo biloba against hepatotoxicity and nephrotoxicity in uranium-treated mice. J Med Food. 2010;13(1):179-188
41. Bondy SC, Guo SX. Lead potentiates iron-induced formation of reactive oxygen species. Toxicol Lett. 1996;87(2-3):109-12
42. Aebi H, Packer L. Catalase in vitro. Meth Enzymol. 1984;105:121-6
43. Beauchamp PC, Fridovich I. Superoxide dismutase: Improved assay and an assay applicable to PAGE. Anal Biochem. 1971;44:276-87
44. Ohkawa H, Ohisi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979;95(2):351-8
45. Levine RL, Garland D, Oliver CN, Amici A, Climent I, Lenz A, Ahn B, Shaltiel S, Stadtman ER. Determination of carbonyl content in oxidatively modified proteins. Meth Enzymol. 1990;186:464-78
46. Berlin A, Schaller KH. European standard method for the determination of delta aminolevulinic acid dehydratase activity in blood. Zeitschrift fur Klinische Biochemie. 1974;12:389-90
47. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin Phenol reagent. J Biol Chem. 1951;193:265-75
48. Velaga MK, Yallapragada PR, Williams D, Rajanna S, Bettaiya R. Hydroalcoholic seed extract of Coriandrum (Coriander) alleviates lead-induced oxidative stress in different regions of rat brain. Biol Trace Elem Res. 2014;159:351-63
49. Stohs SJ, Bagchi D. Oxidative mechanism in the toxicity of metal ions. Free Radical Biol Med. 1995;48:321-48
50. Halliwell, B, Gutteridge JMC. Free radicals in biology and medicine, 2nd edition. London: Cherendon Press; 1989
51. Marnett LJ. Lipid peroxidation: DNA damage by malondialdehyde. Mutat Res Fund Mol Mech Mutagen. 1999;424:83-95
52. Tandon SK, Singh S, Prasad S, Srivatsva, Siddiqui MKJ. Reversal of lead-induced oxidative stress by chelating agent, antioxidant and their combination in the rat. Environ Res. 2002;90:61-6
53. Louajri A, Harraga S, Gedot V, Toubin G, Kantelip JP, Magnin P. The effect of Ginkgo biloba extract on free radical production in hypoxic rats. Biol Pharmacol Bull. 2001;24(6):710-2
54. Boveris AD, Galleano M, Puntarulo S. In vivo supplementation with Ginkgo biloba protects membranes against lipid peroxidation. Phytother Res. 2007;21(8):735-40
55. Marcocci PL, Sckaki A, Albert GM. Antioxidant action of Ginkgo biloba extract EGb 761. Meth Enzymol. 1994;234:462-75
56. Maitra I, Marcocci L, Droy-Lefaix MT, Packer L. Peroxyl scavenging activity of Ginkgo biloba extract EGb 761. Biochem Pharmacol. 1995; 49:1649-55
57. Oyama Y, Chikahisa L, Ueha T, Kanemaru K, Noda K. Ginkgo biloba extract protects brain neurons against oxidative stress induced by hydrogen peroxide. Brain Res. 1996;712:349-52
58. Yucheng N, Baolu Z, Jingwu H, Wenjuan X. Preventive effect of Ginkgo biloba extract on apoptosis in rat cerebellar neuronal cells induced by hydroxyl radicals. Neurosci Lett. 1996;214:115-18
59. Bennet C, Bettaiya R, Rajanna S, Baker L, Yallapragada PR, Bokara KK. Region-specific increase in the antioxidant enzymes and lipid peroxidation products in the brain of rats exposed to lead. Free Radical Res. 2007; 41(3):267-73
60. Farmand F, Ehdale A, Roberts CK, Sindhu RK. Leadinduced dysregulation of superoxide dismutase, catalase, glutathione peroxidase, and guanylate cyclase. Environ Res. 2005;98:33-9
61. Vaziri ND, Lin C, Farmand F, Sindhu RK. Superoxide dismutase, catalase, glutathione peroxidase and NADPH oxidase in lead-induced hypertension. Kidney Int. 2003;63:186-94
62. Tandon SK, Singh S, Prasad S, Khandekar K, Dwivedi VK, Chatterjee M, Mathur N. Reversal of cadmium induced oxidative stress by chelating agent, antioxidant and their combination. Toxicol Lett. 2003;145:211-7
63. Kant V, Mehta M, Varshneya C, Chauhan S. Induction of oxidative stress by sub acute oral exposure of cadmium sulphate in poultry. Brez J Vet Pathol. 2011;4(2):117-21
64. Mates JM, Perez-Gomez C, Nunez de Castro I. Antioxidant enzymes and human disease. Clin Biochem. 1999;32:595-603
65. Yin SJ, Lin TH. Lead catalyzed peroxidation of essential unsaturated fatty acids. Biol Trace Ele Res. 1995;50:167-72
66. Dalle-Donne I, Rossi R, Giustarini D, Milzani A, Colombo R. Protein carbonyl groups as biomarkers of oxidative stress. Clin Chim Acta. 2003;329:23-38
67. Faran JP, Wigfield DC. Biomonitoring of lead exposure with ALAD activity ratios. Int Arch Occup Environ Health. 1982;51:15-24
68. Bechara EJH. Oxidative stress in acute intermittent porphyria and lead poisoning may be triggered by 5-aminolevulinic acid. Braz J Med Biol Res. 1996;29:841-51.