Reversal of cadmium induced oxidative stress by chelating agent, antioxidant or their combination in rat

Toxicology Letters

Volumn 145, Issue 3, 2003, Pages 211-217

  Tandon, S K ^a,b   Singh, S ^a   Prasad, S ^a   Khandekar, K ^a   Dwivedi, V K ^a   Chatterjee, M ^a   Mathur, N ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b NONE   (India)

Author keywords

Antioxidant; Cadmium; Chelation; Oxidative stress; Rat

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; CADMIUM; CATALASE; CHELATING AGENT; GLUTATHIONE; GLUTATHIONE DISULFIDE; MALONALDEHYDE; MANNITOL; MONOISOAMYL 2,3 DIMERCAPTOSUCCINATE; SUCCINIC ACID DERIVATIVE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BODY BURDEN; BRAIN LEVEL; CONTROLLED STUDY; DRUG EFFECT; ENZYME BLOOD LEVEL; INTOXICATION; LIVER LEVEL; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; TISSUE LEVEL;

ANIMALIA;

EID: 0142185297     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(03)00265-0     Document Type: Article

References (21)

1. Andersen O. Principles and recent developments in chelation treatment of metal intoxication. Chem. Rev. 99:1999;2683-2710.
2. Bray T.M., Taylor C.G. Tissue glutathione, nutrition and oxidative stress. Can. J. Physiol. Pharmacol. 71:1993;746-775.
3. Farris M.W. Cadmium toxicity: unique cytoprotective properties of α-tocopheryl succinate in hepatocytes. Toxicology. 69:1991;63-77.
4. Goyer R.A., Cherian M.G., Jones M.M., Reigart J.R. Role of chelating agents for prevention, intervention and treatment of exposures to toxic metals. Environ. Health Perspect. 103:1995;1048-1052.
5. Hudecova A., Ginter E. The influence of ascorbic acid on lipid peroxidation in guinea pigs intoxicated with cadmium. Food Chem. Toxicol. 30:1992;1011-1013.
6. Jones M.M., Singh P.K., Gale G.R., Smith A.B., Atkins L.M. Cadmium mobilization in vivo by intraperitoneal or oral administration of monoalkyl esters of meso-2,3-dimercaptosuccinic acid in mouse. Pharmacol. Toxicol. 70:1992;336-343.
7. Kakkar P., Das B., Vishwanathan P.N. A modified spectrophotometric assay of superoxide dismutase. Ind. J. Biochem. Biophys. 21:1984;130-132.
8. Kelley C., Sargent D.E., Uno J.K. Cadmium therapeutic agents. Curr. Pharm. Des. 5:1999;229-240.
9. Kuo C.H., Maita K., Sleight S.D., Hook J.B. Lipid peroxidation: a possible mechanism of cephaloridine-induced nephrotoxicity. Toxicol. Appl. Pharmacol. 67:1993;78-88.
10. Manca D., Ricard A.C., Trottier B., Chevalier G. Studies on lipid peroxidation in rat tissues following administration of low and moderate doses of cadmium chloride. Toxicology. 67:1991;303-323.
11. Muller L. Consequences of cadmium toxicity in rat hepatocytes: mitochondrial dysfunction and lipid peroxidation. Toxicology. 40:1986;285-292.
12. Nordberg, G.F., Nordberg, M., 1988. In: Clarkson, T.W., Friberg, L., Nordberg, G.F., Sager, P.R. (Eds.), Biological Monitoring of Trace Metals, vol. 151. Plenum Press, New York.
13. Nordberg, G.F., Herber, R.F.M., Allessio, L. (Eds.), 1992. Cadmium in the Human Environment: Toxicity and Carcinogenicity. IARC, Lyon, France.
14. Peters J.M., Thomas D., Falk H., Oberdorster G., Smith T.J. Contribution of metals to respiratory cancer. Environ. Health Perspect. 70:1986;71-83.
15. Saffron L. Australia cuts cadmium in food. Environ. Health Perspect. 109:2001;A158.
16. Sinha A.K. Colorimetric assay of catalase. Anal. Biochem. 47:1972;389-394.
17. Stocks J., Dormandy T.L. Autoxidation of red cell lipids induced by hydrogen peroxide. Br. J. Haematol. 20:1971;95-111.
18. Stohs S.J., Bagchi D. Oxidative mechanisms in the toxicity of metal ions. Free Rad. Biol. Med. 48:1995;321-348.
19. Wilber K.M., Boerhein F., Shapiro O.W. The thiobarbituric acid reagent as a test for the oxidation of unsaturated fatty acids by various reagents. Arch. Biochem. Biophys. 24:1949;304-311.
20. WHO, 1992. Cadmium, Environmental Health Criteria, vol. 134. International Progress in Chemical Safety, WHO, Geneva.
21. Zar, J.H., 1984. Biostatistical Analysis, second ed., Prentice Hall, Englewood cliffs, NJ, pp. 222-226.