메뉴 건너뛰기




Volumn 4, Issue 7, 2015, Pages 543-550

Notch intracellular domain overexpression in adipocytes confers lipodystrophy in mice

Author keywords

Adipocyte; Adipogenesis; Insulin resistance; Lipodystrophy; Lipogenesis; Notch

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN BETA; MEMBRANE PROTEIN; NOTCH INTRACELLULAR DOMAIN PROTEIN; NOTCH RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; UNCLASSIFIED DRUG;

EID: 84931577963     PISSN: None     EISSN: 22128778     Source Type: Journal    
DOI: 10.1016/j.molmet.2015.04.004     Document Type: Article
Times cited : (29)

References (25)
  • 2
    • 79957920754 scopus 로고    scopus 로고
    • Inflammatory links between obesity and metabolic disease
    • Lumeng C.N., Saltiel A.R. Inflammatory links between obesity and metabolic disease. Journal of Clinical Investigation 2011, 121(6):2111-2117.
    • (2011) Journal of Clinical Investigation , vol.121 , Issue.6 , pp. 2111-2117
    • Lumeng, C.N.1    Saltiel, A.R.2
  • 3
    • 76049099665 scopus 로고    scopus 로고
    • Adipose tissue expandability, lipotoxicity and the metabolic syndrome-an allostatic perspective
    • Virtue S., Vidal-Puig A. Adipose tissue expandability, lipotoxicity and the metabolic syndrome-an allostatic perspective. Biochimica et Biophysica Acta 2010, 1801(3):338-349.
    • (2010) Biochimica et Biophysica Acta , vol.1801 , Issue.3 , pp. 338-349
    • Virtue, S.1    Vidal-Puig, A.2
  • 4
    • 80655145234 scopus 로고    scopus 로고
    • Clinical review#: Lipodystrophies: genetic and acquired body fat disorders
    • Garg A. Clinical review#: Lipodystrophies: genetic and acquired body fat disorders. Journal of Clinical Endocrinology and Metabolism 2011, 96(11):3313-3325.
    • (2011) Journal of Clinical Endocrinology and Metabolism , vol.96 , Issue.11 , pp. 3313-3325
    • Garg, A.1
  • 5
    • 70549098559 scopus 로고    scopus 로고
    • Mouse models of inherited lipodystrophy
    • Savage D.B. Mouse models of inherited lipodystrophy. Disease Models & Mechanisms 2009, 2(11-12):554-562.
    • (2009) Disease Models & Mechanisms , vol.2 , Issue.11-12 , pp. 554-562
    • Savage, D.B.1
  • 6
    • 37349063135 scopus 로고    scopus 로고
    • Mouse models of lipodystrophy key reagents for the understanding of the metabolic syndrome
    • Asterholm I.W., Halberg N., Scherer P.E. Mouse models of lipodystrophy key reagents for the understanding of the metabolic syndrome. Drug Discovery Today Disease Models 2007, 4(1):17-24.
    • (2007) Drug Discovery Today Disease Models , vol.4 , Issue.1 , pp. 17-24
    • Asterholm, I.W.1    Halberg, N.2    Scherer, P.E.3
  • 7
    • 84865241459 scopus 로고    scopus 로고
    • The Notch signalling system: recent insights into the complexity of a conserved pathway
    • Guruharsha K.G., Kankel M.W., Artavanis-Tsakonas S. The Notch signalling system: recent insights into the complexity of a conserved pathway. Nature Reviews Genetics 2012, 13(9):654-666.
    • (2012) Nature Reviews Genetics , vol.13 , Issue.9 , pp. 654-666
    • Guruharsha, K.G.1    Kankel, M.W.2    Artavanis-Tsakonas, S.3
  • 9
    • 1842452938 scopus 로고    scopus 로고
    • Dual roles for the Notch target gene Hes-1 in the differentiation of 3T3-L1 preadipocytes
    • Ross D.A., Rao P.K., Kadesch T. Dual roles for the Notch target gene Hes-1 in the differentiation of 3T3-L1 preadipocytes. Molecular and Cellular Biology 2004, 24(8):3505-3513.
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.8 , pp. 3505-3513
    • Ross, D.A.1    Rao, P.K.2    Kadesch, T.3
  • 10
    • 0030662043 scopus 로고    scopus 로고
    • Notch-1 controls the expression of fatty acid-activated transcription factors and is required for adipogenesis
    • Garces C., Ruiz-Hidalgo M.J., Font de Mora J., Park C., Miele L., Goldstein J., et al. Notch-1 controls the expression of fatty acid-activated transcription factors and is required for adipogenesis. Journal of Biological Chemistry 1997, 272(47):29729-29734.
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.47 , pp. 29729-29734
    • Garces, C.1    Ruiz-Hidalgo, M.J.2    Font de Mora, J.3    Park, C.4    Miele, L.5    Goldstein, J.6
  • 12
    • 84882245596 scopus 로고    scopus 로고
    • Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability
    • Pajvani U.B., Qiang L., Kangsamaksin T., Kitajewski J., Ginsberg H.N., Accili D. Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability. Nature Medicine 2013, 19(8):1054-1060.
    • (2013) Nature Medicine , vol.19 , Issue.8 , pp. 1054-1060
    • Pajvani, U.B.1    Qiang, L.2    Kangsamaksin, T.3    Kitajewski, J.4    Ginsberg, H.N.5    Accili, D.6
  • 15
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Research 2001, 29(9):e45.
    • (2001) Nucleic Acids Research , vol.29 , Issue.9 , pp. e45
    • Pfaffl, M.W.1
  • 16
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biology 2002, 3(7). RESEARCH0034.
    • (2002) Genome Biology , vol.3 , Issue.7
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6
  • 17
    • 84892702771 scopus 로고    scopus 로고
    • Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch
    • Cohen P., Levy J.D., Zhang Y., Frontini A., Kolodin D.P., Svensson K.J., et al. Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch. Cell 2014, 156(1-2):304-316.
    • (2014) Cell , vol.156 , Issue.1-2 , pp. 304-316
    • Cohen, P.1    Levy, J.D.2    Zhang, Y.3    Frontini, A.4    Kolodin, D.P.5    Svensson, K.J.6
  • 19
    • 84887502374 scopus 로고    scopus 로고
    • Tracking adipogenesis during white adipose tissue development, expansion and regeneration
    • Wang Q.A., Tao C., Gupta R.K., Scherer P.E. Tracking adipogenesis during white adipose tissue development, expansion and regeneration. Nature Medicine 2013, 19(10):1338-1344.
    • (2013) Nature Medicine , vol.19 , Issue.10 , pp. 1338-1344
    • Wang, Q.A.1    Tao, C.2    Gupta, R.K.3    Scherer, P.E.4
  • 21
    • 51549107903 scopus 로고    scopus 로고
    • Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism
    • Cao H., Gerhold K., Mayers J.R., Wiest M.M., Watkins S.M., Hotamisligil G.S. Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism. Cell 2008, 134(6):933-944.
    • (2008) Cell , vol.134 , Issue.6 , pp. 933-944
    • Cao, H.1    Gerhold, K.2    Mayers, J.R.3    Wiest, M.M.4    Watkins, S.M.5    Hotamisligil, G.S.6
  • 23
    • 0344010662 scopus 로고    scopus 로고
    • CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma
    • Herzig S., Hedrick S., Morantte I., Koo S.H., Galimi F., Montminy M. CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma. Nature 2003, 426(6963):190-193.
    • (2003) Nature , vol.426 , Issue.6963 , pp. 190-193
    • Herzig, S.1    Hedrick, S.2    Morantte, I.3    Koo, S.H.4    Galimi, F.5    Montminy, M.6
  • 24
    • 84916942507 scopus 로고    scopus 로고
    • Notch signaling pathway activation in normal and hyperglycemic rats differs in the stem cells of visceral and subcutaneous adipose tissue
    • Ferrer-Lorente R., Bejar M.T., Badimon L. Notch signaling pathway activation in normal and hyperglycemic rats differs in the stem cells of visceral and subcutaneous adipose tissue. Stem Cells and Development 2014, 23(24):3034-3048.
    • (2014) Stem Cells and Development , vol.23 , Issue.24 , pp. 3034-3048
    • Ferrer-Lorente, R.1    Bejar, M.T.2    Badimon, L.3
  • 25
    • 84905740317 scopus 로고    scopus 로고
    • Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity
    • Bi P., Shan T., Liu W., Yue F., Yang X., Liang X.R., et al. Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity. Nature Medicine 2014, 20(8):911-918.
    • (2014) Nature Medicine , vol.20 , Issue.8 , pp. 911-918
    • Bi, P.1    Shan, T.2    Liu, W.3    Yue, F.4    Yang, X.5    Liang, X.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.