Brief report: Oxidative stress mediates cardiomyocyte apoptosis in a human model of danon disease and heart failure

Stem Cells

Volumn 33, Issue 7, 2015, Pages 2343-2350

  Hashem, Sherin I ^a   Perry, Cynthia N ^a   Bauer, Matthieu ^a   Han, Sangyoon ^a   Clegg, Stacey D ^b   Ouyang, Kunfu ^a   Deacon, Dekker C ^a   Spinharney, Mary ^a   Panopoulos, Athanasia D ^c   Izpisua Belmonte, Juan Carlos ^c   Frazer, Kelly A ^d,e   Chen, Ju ^a   Gong, Qiuming ^b   Zhou, Zhengfeng ^b   Chi, Neil C ^a,e   Adler, Eric D ^a  

^a UnityPoint Clinic   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; Autophagy; Danon disease; Induced pluripotent stem cells; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; CALCIUM; FREE RADICAL; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MESSENGER RNA; NATRIURETIC FACTOR; THIOL DERIVATIVE;

APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CASE REPORT; CELL MATURATION; CELL SIZE; CONTROLLED STUDY; DANON DISEASE; GENE MUTATION; HEART FAILURE; HEART MUSCLE CELL; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PATHOGENESIS; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; CARDIAC MUSCLE CELL; GENETICS; INDUCED PLURIPOTENT STEM CELL; METABOLISM; PATHOLOGY;

APOPTOSIS; AUTOPHAGY; GLYCOGEN STORAGE DISEASE TYPE IIB; HEART FAILURE; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MYOCYTES, CARDIAC; OXIDATIVE STRESS;

EID: 84931574633     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2015     Document Type: Article

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