Curcumin ameliorates high glucose-induced neural tube defects by suppressing cellular stress and apoptosis

American Journal of Obstetrics and Gynecology

Volumn 212, Issue 6, 2015, Pages 802.e1-802.e8

  Wu, Yanqing ^a,b   Wang, Fang ^b   Albert Reece, E ^b   Yang, Peixin ^b  

^a FUJIAN NORMAL UNIVERSITY   (China)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

caspase activation; curcumin; endoplasmic reticulum stress; high glucose; neural tube defects; nitrosative stress; oxidative stress

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; CASPASE 3; CASPASE 8; CCAAT ENHANCER BINDING PROTEIN; CURCUMIN; GLUCOSE; INITIATION FACTOR 2ALPHA; LIPID PEROXIDE; MESSENGER RNA; PHOSPHORYLATED INOSITOL REQUIRING PROTEIN 1 ALPHA; PROTEIN; PROTEIN KINASE R; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL STRESS; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; LIPID PEROXIDATION; MOUSE; NEURAL TUBE DEFECT; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RNA SPLICING; ANIMAL; C57BL MOUSE; CELL FUNCTION; CHEMICALLY INDUCED; DRUG EFFECTS; NEURAL TUBE DEFECTS; PHYSIOLOGY;

ANIMALS; APOPTOSIS; CASPASE 3; CELL PHYSIOLOGICAL PHENOMENA; CURCUMIN; ENDOPLASMIC RETICULUM STRESS; GLUCOSE; MICE; MICE, INBRED C57BL; NEURAL TUBE DEFECTS; OXIDATIVE STRESS;

EID: 84931573444     PISSN: 00029378     EISSN: 10976868     Source Type: Journal    
DOI: 10.1016/j.ajog.2015.01.017     Document Type: Article

References (57)

1. M.A. Ramos-Arroyo, E. Rodriguez-Pinilla, and J.F. Cordero Maternal diabetes: the risk for specific birth defects Eur J Epidemiol 8 1992 503 508
2. J.E. Becerra, M.J. Khoury, J.F. Cordero, and J.D. Erickson Diabetes mellitus during pregnancy and the risks for specific birth defects: a population-based case-control study Pediatrics 85 1990 1 9
3. P. Yang, Z. Zhao, and E.A. Reece Activation of oxidative stress signaling that is implicated in apoptosis with a mouse model of diabetic embryopathy Am J Obstet Gynecol 198 2008 130.e1 130.e7
4. E.A. Reece, A. Wiznitzer, C.J. Homko, Z. Hagay, and Y.K. Wu Synchronization of the factors critical for diabetic teratogenesis: an in vitro model Am J Obstet Gynecol 174 1996 1284 1288
5. A. Correa, S.M. Gilboa, and L.M. Besser Diabetes mellitus and birth defects Am J Obstet Gynecol 199 2008 237.e1 237.e9
6. P. Yang, and H. Li Epigallocatechin-3-gallate ameliorates hyperglycemia-induced embryonic vasculopathy and malformation by inhibition of Foxo3a activation Am J Obstet Gynecol 203 2010 75.e1 75.e6
7. C. Xu, X. Li, F. Wang, H. Weng, and P. Yang Trehalose prevents neural tube defects by correcting maternal diabetes-suppressed autophagy and neurogenesis Am J Physiol Endocrinol Metab 305 2013 E667 E678
8. A. Correa, L. Botto, Y. Liu, J. Mulinare, and J.D. Erickson Do multivitamin supplements attenuate the risk for diabetes-associated birth defects? Pediatrics 111 2003 1146 1151
9. F. Grodstein, J. O'Brien, and J.H. Kang Long-term multivitamin supplementation and cognitive function in men: a randomized trial Ann Intern Med 159 2013 806 814
10. E. Guallar, S. Stranges, C. Mulrow, L.J. Appel, and E.R. Miller III Enough is enough: stop wasting money on vitamin and mineral supplements Ann Intern Med 159 2013 850 851
11. C.H. Hsu, Y.L. Liao, S.C. Lin, T.H. Tsai, C.J. Huang, and P. Chou Does supplementation with green tea extract improve insulin resistance in obese type 2 diabetics? A randomized, double-blind, and placebo-controlled clinical trial Altern Med Rev 16 2011 157 163
12. H.P. Ammon, and M.A. Wahl Pharmacology of Curcuma longa Planta Med 57 1991 1 7
13. S. Rungseesantivanon, N. Thenchaisri, P. Ruangvejvorachai, and S. Patumraj Curcumin supplementation could improve diabetes-induced endothelial dysfunction associated with decreased vascular superoxide production and PKC inhibition BMC Complement Altern Med 10 2010 57
14. J.M. Zingg, S.T. Hasan, and M. Meydani Molecular mechanisms of hypolipidemic effects of curcumin Biofactors 39 2013 101 121
15. H. Farhangkhoee, Z.A. Khan, S. Chen, and S. Chakrabarti Differential effects of curcumin on vasoactive factors in the diabetic rat heart Nutr Metab 3 2006 27
16. B. Chhunchha, N. Fatma, E. Kubo, P. Rai, S.P. Singh, and D.P. Singh Curcumin abates hypoxia-induced oxidative stress based-ER stress-mediated cell death in mouse hippocampal cells (HT22) by controlling Prdx6 and NF-kappaB regulation Am J Physiol Cell Physiol 304 2013 C636 C655
17. P. Yang, X. Li, and C. Xu Maternal hyperglycemia activates an ASK1-FoxO3a-caspase 8 pathway that leads to embryonic neural tube defects Sci Signal 6 2013 ra74
18. X. Li, H. Weng, E.A. Reece, and P. Yang SOD1 overexpression in vivo blocks hyperglycemia-induced specific PKC isoforms: substrate activation and consequent lipid peroxidation in diabetic embryopathy Am J Obstet Gynecol 205 2011 84.e1 84.e6
19. F. Wang, E.A. Reece, and P. Yang Superoxide dismutase 1 overexpression in mice abolishes maternal diabetes-induced endoplasmic reticulum stress in diabetic embryopathy Am J Obstet Gynecol 209 2013 345.e1 345.e7
20. X. Li, C. Xu, and P. Yang c-Jun NH2-terminal kinase 1/2 and endoplasmic reticulum stress as interdependent and reciprocal causation in diabetic embryopathy Diabetes 62 2013 599 608
21. F. Giacco, and M. Brownlee Oxidative stress and diabetic complications Circ Res 107 2010 1058 1070
22. H. Weng, X. Li, E.A. Reece, and P. Yang SOD1 suppresses maternal hyperglycemia-increased iNOS expression and consequent nitrosative stress in diabetic embryopathy Am J Obstet Gynecol 206 2012 448.e1 448.e7
23. P. Yang, Y. Cao, and H. Li Hyperglycemia induces inducible nitric oxide synthase gene expression and consequent nitrosative stress via c-Jun N-terminal kinase activation Am J Obstet Gynecol 203 2010 185.e5 185.e11
24. Y. Cao, Z. Zhao, R.L. Eckert, and E.A. Reece The essential role of protein kinase C delta in diabetes-induced neural tube defects J Matern Fetal Neonatal Med 25 2012 2020 2024
25. P. Yang, Z. Zhao, and E.A. Reece Involvement of c-Jun N-terminal kinases activation in diabetic embryopathy Biochem Biophys Res Commun 357 2007 749 754
26. J.W. Smyth, T.T. Hong, and D. Gao Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium J Clin Invest 120 2010 266 279
27. Y. Wang, S. Zhou, and W. Sun Inhibition of JNK by novel curcumin analog C66 prevents diabetic cardiomyopathy with a preservation of cardiac metallothionein expression Am J Physiol Endocrinol Metab 306 2014 E1239 E1247
28. F. Wang, Y. Wu, and H. Gu Ask1 gene deletion blocks maternal diabetes-induced endoplasmic reticulum stress in the developing embryo by disrupting the unfolded protein response signalosome Diabetes 2014 Sep 23 [Epub ahead of print]
29. G. Jing, J.J. Wang, and S.X. Zhang ER stress and apoptosis: a new mechanism for retinal cell death Exp Diabetes Res 2012 2012 589589
30. D.L. Eizirik, A.K. Cardozo, and M. Cnop The role for endoplasmic reticulum stress in diabetes mellitus Endocr Rev 29 2008 42 61
31. X. Li, H. Weng, C. Xu, E.A. Reece, and P. Yang Oxidative stress-induced JNK1/2 activation triggers proapoptotic signaling and apoptosis that leads to diabetic embryopathy Diabetes 61 2012 2084 2092
32. R. Bryk, P. Griffin, and C. Nathan Peroxynitrite reductase activity of bacterial peroxiredoxins Nature 407 2000 211 215
33. E. Sivan, Y.C. Lee, Y.K. Wu, and E.A. Reece Free radical scavenging enzymes in fetal dysmorphogenesis among offspring of diabetic rats Teratology 56 1997 343 349
34. N. Fatma, P. Singh, and B. Chhunchha Deficiency of Prdx6 in lens epithelial cells induces ER stress response-mediated impaired homeostasis and apoptosis Am J Physiol Cell Physiol 301 2011 C954 C967
35. R.J. Shiau, P.C. Shih, and Y.D. Wen Effect of silymarin on curcumin-induced mortality in zebrafish (Danio rerio) embryos and larvae Indian J Exp Biol 49 2011 491 497
36. C.D. Lao, M.F. Demierre, and V.K. Sondak Targeting events in melanoma carcinogenesis for the prevention of melanoma Expert Rev Anticancer Ther 6 2006 1559 1568
37. A.L. Cheng, C.H. Hsu, and J.K. Lin Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions Anticancer Res 21 2001 2895 2900
38. E. Chroni, E. Pasmatzi, and A. Monastirli Short-term oral isotretinoin therapy does not cause clinical or subclinical peripheral neuropathy J Dermatolog Treat 17 2006 6 8
39. J.Y. Wu, C.Y. Lin, T.W. Lin, C.F. Ken, and Y.D. Wen Curcumin affects development of zebrafish embryo Biol Pharma Bull 30 2007 1336 1339
40. F.J. Huang, K.C. Lan, and H.Y. Kang Effect of curcumin on in vitro early post-implantation stages of mouse embryo development Eur J Obstet Gynecol Reprod Biol 166 2013 47 51
41. N. Desai, A. Roman, and B. Rochelson Maternal metformin treatment decreases fetal inflammation in a rat model of obesity and metabolic syndrome Am J Obstet Gynecol 209 2013 136.e1 136.e9
42. K. Castorino, and L. Jovanovic Pregnancy and diabetes management: advances and controversies Clin Chem 57 2011 221 230
43. C. Louik, P. Gardiner, K. Kelley, and A.A. Mitchell Use of herbal treatments in pregnancy Am J Obstet Gynecol 202 2010 439.e1 439.e10
44. S.E. Parker, M.M. Yazdy, S.C. Tinker, A.A. Mitchell, and M.M. Werler The impact of folic acid intake on the association among diabetes mellitus, obesity, and spina bifida Am J Obstet Gynecol 209 2013 239.e1 239.e8
45. E.G. Noble Is blood-flow-restricted low-load resistance exercise really stress free? Acta Physiol (Oxf) 211 2014 541 543
46. R. Beloosesky, Y. Ginsberg, and N. Khatib Prophylactic maternal N-acetylcysteine in rats prevents maternal inflammation-induced offspring cerebral injury shown on magnetic resonance imaging Am J Obstet Gynecol 208 2013 213.e1 213.e6
47. L.K. Sween, A.D. Althouse, and J.M. Roberts Early-pregnancy percent body fat in relation to preeclampsia risk in obese women Am J Obstet Gynecol 212 2015 84.e1 84.e7
48. H.K. Ahmadzia, S.M. Thomas, A.M. Dude, C.A. Grotegut, and B.K. Boyd Prediction of birthweight from third-trimester ultrasound in morbidly obese women Am J Obstet Gynecol 211 2014 431.e1 431.e7
49. O. Acosta, V.I. Ramirez, and S. Lager Increased glucose and placental GLUT-1 in large infants of obese nondiabetic mothers Am J Obstet Gynecol 212 2015 227.e1 227.e7
50. J.L. Miller, M. de Veciana, and S. Turan First-trimester detection of fetal anomalies in pregestational diabetes using nuchal translucency, ductus venosus Doppler, and maternal glycosylated hemoglobin Am J Obstet Gynecol 208 2013 385.e1 385.e8
51. R.O. Bahado-Singh, R. Ertl, and R. Mandal Metabolomic prediction of fetal congenital heart defect in the first trimester Am J Obstet Gynecol 211 2014 240.e1 240.e14
52. M.F. Greene, J.W. Hare, J.P. Cloherty, B.R. Benacerraf, and J.S. Soeldner First-trimester hemoglobin A1 and risk for major malformation and spontaneous abortion in diabetic pregnancy Teratology 39 1989 225 231
53. B.A. Kase, H. Northrup, and K.S. Au Novel single nucleotide polymorphisms in the superoxide dismutase 1 and 2 genes among children with myelomeningocele Am J Obstet Gynecol 209 2013 388.e1 388.e7
54. R.O. Bahado-Singh, R. Akolekar, and A. Chelliah Metabolomic analysis for first-trimester trisomy 18 detection Am J Obstet Gynecol 209 2013 65.e1 65.e9
55. R.O. Bahado-Singh, R. Akolekar, and R. Mandal Metabolomic analysis for first-trimester Down syndrome prediction Am J Obstet Gynecol 208 2013 371.e1 371.e8
56. A. Correa, S.M. Gilboa, and L.D. Botto Lack of periconceptional vitamins or supplements that contain folic acid and diabetes mellitus-associated birth defects Am J Obstet Gynecol 206 2012 218.e1 218.e13
57. G.P. Oakley Jr. Failing to prevent birth defects caused by maternal diabetes mellitus Am J Obstet Gynecol 206 2012 179 180