Engineering superactive granulocyte macrophage colony-stimulating factor transferrin fusion proteins as orally-delivered candidate agents for treating neurodegenerative disease

Biotechnology Progress

Volumn 31, Issue 3, 2015, Pages 668-677

  Heinzelman, Pete ^a   Priebe, Molly C ^a  

^a University of Oklahoma   (United States)

Author keywords

Alzheimer's disease; Granulocyte macrophage colony stimulating factor (GM CSF); Parkinson's disease; Transferrin receptor; Yeast surface display

Indexed keywords

ANIMALS; BINDING ENERGY; DIAGNOSIS; LIBRARIES; NEURODEGENERATIVE DISEASES; PLASMONS; PROTEINS; SURFACE PLASMON RESONANCE; YEAST;

ALZHEIMER'S DISEASE; GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTORS; PARKINSON'S DISEASE; TRANSFERRIN RECEPTORS; YEAST SURFACE DISPLAYS;

MACROPHAGES;

ANIMALIA;

CD131 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; HYBRID PROTEIN; TRANSFERRIN;

ALZHEIMER DISEASE; BIOSYNTHESIS; CELL LINE; CELL PROLIFERATION; DOSE RESPONSE; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; NEURODEGENERATIVE DISEASES; ORAL DRUG ADMINISTRATION; PARKINSON DISEASE; SURFACE PLASMON RESONANCE; YEAST;

ADMINISTRATION, ORAL; ALZHEIMER DISEASE; CELL LINE; CELL PROLIFERATION; CYTOKINE RECEPTOR COMMON BETA SUBUNIT; DOSE-RESPONSE RELATIONSHIP, DRUG; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; NEURODEGENERATIVE DISEASES; PARKINSON DISEASE; RECEPTORS, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; RECOMBINANT FUSION PROTEINS; SURFACE PLASMON RESONANCE; TRANSFERRIN; YEASTS;

EID: 84931567240     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.2071     Document Type: Article

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