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Volumn 29, Issue 4, 2015, Pages 1540-1550

The androgen receptor confers protection against diet-induced atherosclerosis, obesity, and dyslipidemia in female mice

Author keywords

Genetically altered mice; Metabolism; Sex hormones

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; APOLIPOPROTEIN E; TRIACYLGLYCEROL; CHOLESTEROL;

EID: 84931452064     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-259234     Document Type: Article
Times cited : (45)

References (57)
  • 2
    • 78650521925 scopus 로고    scopus 로고
    • Estrogen and androgen receptors: Regulators of fuel homeostasis and emerging targets for diabetes and obesity
    • Mauvais-Jarvis, F. (2011) Estrogen and androgen receptors: regulators of fuel homeostasis and emerging targets for diabetes and obesity. Trends Endocrinol. Metab. 22, 24-33
    • (2011) Trends Endocrinol. Metab. , vol.22 , pp. 24-33
    • Mauvais-Jarvis, F.1
  • 4
    • 70549086629 scopus 로고    scopus 로고
    • The effects of testosterone on risk factors for, and the mediators of, the atherosclerotic process
    • Jones, T. H., and Saad, F. (2009) The effects of testosterone on risk factors for, and the mediators of, the atherosclerotic process. Atherosclerosis 207, 318-327
    • (2009) Atherosclerosis , vol.207 , pp. 318-327
    • Jones, T.H.1    Saad, F.2
  • 6
    • 23844526146 scopus 로고    scopus 로고
    • Female androgen deficiency syndrome - An unproven hypothesis
    • Bhasin, S. (2005) Female androgen deficiency syndrome - an unproven hypothesis. J. Clin. Endocrinol. Metab. 90, 4970-4972
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 4970-4972
    • Bhasin, S.1
  • 7
    • 35948990817 scopus 로고    scopus 로고
    • The Endocrine Society Clinical Practice Guideline and The North American Menopause Society position statement on androgen therapy in women: Another one of Yogi's forks
    • Braunstein, G. D. (2007) The Endocrine Society Clinical Practice Guideline and The North American Menopause Society position statement on androgen therapy in women: another one of Yogi's forks. J. Clin. Endocrinol. Metab. 92, 4091-4093
    • (2007) J. Clin. Endocrinol. Metab. , vol.92 , pp. 4091-4093
    • Braunstein, G.D.1
  • 8
    • 77952787136 scopus 로고    scopus 로고
    • Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: A consensus statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society
    • Wild, R. A., Carmina, E., Diamanti-Kandarakis, E., Dokras, A., Escobar-Morreale, H. F., Futterweit, W., Lobo, R., Norman, R. J., Talbott, E., and Dumesic, D. A. (2010) Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society. J. Clin. Endocrinol. Metab. 95, 2038-2049
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , pp. 2038-2049
    • Wild, R.A.1    Carmina, E.2    Diamanti-Kandarakis, E.3    Dokras, A.4    Escobar-Morreale, H.F.5    Futterweit, W.6    Lobo, R.7    Norman, R.J.8    Talbott, E.9    Dumesic, D.A.10
  • 9
    • 59349107509 scopus 로고    scopus 로고
    • Role of androgen excess on metabolic aberrations and cardiovascular risk in women with polycystic ovary syndrome
    • Christakou, C. D., and Diamanti-Kandarakis, E. (2008) Role of androgen excess on metabolic aberrations and cardiovascular risk in women with polycystic ovary syndrome. Womens Health (Lond. Engl.) 4, 583-594
    • (2008) Womens Health (Lond. Engl.) , vol.4 , pp. 583-594
    • Christakou, C.D.1    Diamanti-Kandarakis, E.2
  • 10
    • 58149168753 scopus 로고    scopus 로고
    • Effects of androgens on insulin action in women: Is androgen excess a component of female metabolic syndrome?
    • Corbould, A. (2008) Effects of androgens on insulin action in women: is androgen excess a component of female metabolic syndrome? Diabetes Metab. Res. Rev. 24, 520-532
    • (2008) Diabetes Metab. Res. Rev. , vol.24 , pp. 520-532
    • Corbould, A.1
  • 11
    • 33846991956 scopus 로고    scopus 로고
    • Position statement: Utility, limitations, and pitfalls in measuring testosterone: An Endocrine Society position statement
    • Rosner, W., Auchus, R. J., Azziz, R., Sluss, P. M., and Raff, H. (2007) Position statement: Utility, limitations, and pitfalls in measuring testosterone: an Endocrine Society position statement. J. Clin. Endocrinol. Metab. 92, 405-413
    • (2007) J. Clin. Endocrinol. Metab. , vol.92 , pp. 405-413
    • Rosner, W.1    Auchus, R.J.2    Azziz, R.3    Sluss, P.M.4    Raff, H.5
  • 12
    • 0038307297 scopus 로고    scopus 로고
    • Androgens and cardiovascular disease
    • Liu, P. Y., Death, A. K., and Handelsman, D. J. (2003) Androgens and cardiovascular disease. Endocr. Rev. 24, 313-340
    • (2003) Endocr. Rev. , vol.24 , pp. 313-340
    • Liu, P.Y.1    Death, A.K.2    Handelsman, D.J.3
  • 13
    • 77955638587 scopus 로고    scopus 로고
    • Molecular insights into androgen actions in male and female reproductive function from androgen receptor knockout models
    • Walters, K. A., Simanainen, U., and Handelsman, D. J. (2010) Molecular insights into androgen actions in male and female reproductive function from androgen receptor knockout models. Hum. Reprod. Update 16, 543-558
    • (2010) Hum. Reprod. Update , vol.16 , pp. 543-558
    • Walters, K.A.1    Simanainen, U.2    Handelsman, D.J.3
  • 15
    • 0032030846 scopus 로고    scopus 로고
    • Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase
    • Lallemand, Y., Luria, V., Haffner-Krausz, R., and Lonai, P. (1998) Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase. Transgenic Res. 7, 105-112
    • (1998) Transgenic Res. , vol.7 , pp. 105-112
    • Lallemand, Y.1    Luria, V.2    Haffner-Krausz, R.3    Lonai, P.4
  • 16
    • 0036772574 scopus 로고    scopus 로고
    • Reproductive disturbances, pituitary lactotrope adenomas, and mammary gland tumors in transgenic female mice producing high levels of human chorionic gonadotropin
    • Rulli, S. B., Kuorelahti, A., Karaer, O., Pelliniemi, L. J., Poutanen, M., and Huhtaniemi, I. (2002) Reproductive disturbances, pituitary lactotrope adenomas, and mammary gland tumors in transgenic female mice producing high levels of human chorionic gonadotropin. Endocrinology 143, 4084-4095
    • (2002) Endocrinology , vol.143 , pp. 4084-4095
    • Rulli, S.B.1    Kuorelahti, A.2    Karaer, O.3    Pelliniemi, L.J.4    Poutanen, M.5    Huhtaniemi, I.6
  • 18
    • 0029926597 scopus 로고    scopus 로고
    • Mode of growth hormone administration influences triacylglycerol synthesis and assembly of apolipoprotein B-containing lipoproteins in cultured rat hepatocytes
    • Sjöberg, A., Oscarsson, J., Borén, J., Edén, S., and Olofsson, S. O. (1996) Mode of growth hormone administration influences triacylglycerol synthesis and assembly of apolipoprotein B-containing lipoproteins in cultured rat hepatocytes. J. Lipid Res. 37, 275-289
    • (1996) J. Lipid Res. , vol.37 , pp. 275-289
    • Sjöberg, A.1    Oscarsson, J.2    Borén, J.3    Edén, S.4    Olofsson, S.O.5
  • 20
    • 0037396439 scopus 로고    scopus 로고
    • Endocrine and intracrine sources of androgens in women: Inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone
    • Labrie, F., Luu-The, V., Labrie, C., Bélanger, A., Simard, J., Lin, S. X., and Pelletier, G. (2003) Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone. Endocr. Rev. 24, 152-182
    • (2003) Endocr. Rev. , vol.24 , pp. 152-182
    • Labrie, F.1    Luu-The, V.2    Labrie, C.3    Bélanger, A.4    Simard, J.5    Lin, S.X.6    Pelletier, G.7
  • 21
    • 84857562936 scopus 로고    scopus 로고
    • Preclinical mouse models and methods for the discovery of the causes and treatments of atherosclerosis
    • Hewing, B., and Fisher, E. A. (2012) Preclinical mouse models and methods for the discovery of the causes and treatments of atherosclerosis. Expert Opin Drug Discov 7, 207-216
    • (2012) Expert Opin Drug Discov , vol.7 , pp. 207-216
    • Hewing, B.1    Fisher, E.A.2
  • 22
    • 33845914986 scopus 로고    scopus 로고
    • Mechanisms linking obesity with cardiovascular disease
    • Van Gaal, L. F., Mertens, I. L., and De Block, C. E. (2006) Mechanisms linking obesity with cardiovascular disease. Nature 444, 875-880
    • (2006) Nature , vol.444 , pp. 875-880
    • Van Gaal, L.F.1    Mertens, I.L.2    De Block, C.E.3
  • 24
    • 0029983303 scopus 로고    scopus 로고
    • Effects of the anabolic steroid nandrolone decanoate on plasma lipids and coronary arteries of female cynomolgus macaques
    • Obasanjo, I. O., Clarkson, T. B., and Weaver, D. S. (1996) Effects of the anabolic steroid nandrolone decanoate on plasma lipids and coronary arteries of female cynomolgus macaques. Metabolism 45, 463-468
    • (1996) Metabolism , vol.45 , pp. 463-468
    • Obasanjo, I.O.1    Clarkson, T.B.2    Weaver, D.S.3
  • 25
    • 0029043896 scopus 로고
    • Effects of androgens on coronary artery atherosclerosis and atherosclerosis-related impairment of vascular responsiveness
    • Adams, M. R., Williams, J. K., and Kaplan, J. R. (1995) Effects of androgens on coronary artery atherosclerosis and atherosclerosis-related impairment of vascular responsiveness. Arterioscler. Thromb. Vasc. Biol. 15, 562-570
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 562-570
    • Adams, M.R.1    Williams, J.K.2    Kaplan, J.R.3
  • 26
    • 59649086991 scopus 로고    scopus 로고
    • Androgen-induced progression of arterial calcification in apolipoprotein E-null mice is uncoupled from plaque growth and lipid levels
    • McRobb, L., Handelsman, D. J., and Heather, A. K. (2009) Androgen-induced progression of arterial calcification in apolipoprotein E-null mice is uncoupled from plaque growth and lipid levels. Endocrinology 150, 841-848
    • (2009) Endocrinology , vol.150 , pp. 841-848
    • McRobb, L.1    Handelsman, D.J.2    Heather, A.K.3
  • 29
    • 0027958084 scopus 로고
    • ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree
    • Nakashima, Y., Plump, A. S., Raines, E. W., Breslow, J. L., and Ross, R. (1994) ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler. Thromb. 14, 133-140
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 133-140
    • Nakashima, Y.1    Plump, A.S.2    Raines, E.W.3    Breslow, J.L.4    Ross, R.5
  • 30
    • 13344269692 scopus 로고    scopus 로고
    • Modulation of very low density lipoprotein production and clearance contributes to age- and gender- dependent hyperlipoproteinemia in apolipoprotein E3-Leiden transgenic mice
    • van Vlijmen, B. J., van 't Hof, H. B., Mol, M. J., van der Boom, H., van der Zee, A., Frants, R. R., Hofker, M. H., and Havekes, L. M. (1996) Modulation of very low density lipoprotein production and clearance contributes to age- and gender- dependent hyperlipoproteinemia in apolipoprotein E3-Leiden transgenic mice. J. Clin. Invest. 97, 1184-1192
    • (1996) J. Clin. Invest. , vol.97 , pp. 1184-1192
    • Van Vlijmen, B.J.1    Van 't Hof, H.B.2    Mol, M.J.3    Van Der Boom, H.4    Van Der Zee, A.5    Frants, R.R.6    Hofker, M.H.7    Havekes, L.M.8
  • 31
    • 2442497103 scopus 로고    scopus 로고
    • Effect of the combination of methyltestosterone and esterified estrogens compared with esterified estrogens alone on apolipoprotein CIII and other apolipoproteins in very low density, low density, and high density lipoproteins in surgically postmenopausal women
    • Chiuve, S. E., Martin, L. A., Campos, H., and Sacks, F. M. (2004) Effect of the combination of methyltestosterone and esterified estrogens compared with esterified estrogens alone on apolipoprotein CIII and other apolipoproteins in very low density, low density, and high density lipoproteins in surgically postmenopausal women. J. Clin. Endocrinol. Metab. 89, 2207-2213
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 2207-2213
    • Chiuve, S.E.1    Martin, L.A.2    Campos, H.3    Sacks, F.M.4
  • 32
    • 79953847765 scopus 로고    scopus 로고
    • Sex differences in lipid and lipoprotein metabolism: It's not just about sex hormones
    • Wang, X., Magkos, F., and Mittendorfer, B. (2011) Sex differences in lipid and lipoprotein metabolism: it's not just about sex hormones. J. Clin. Endocrinol. Metab. 96, 885-893
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , pp. 885-893
    • Wang, X.1    Magkos, F.2    Mittendorfer, B.3
  • 34
    • 84861233637 scopus 로고    scopus 로고
    • Sortilin as a regulator of lipoprotein metabolism
    • Strong, A., and Rader, D. J. (2012) Sortilin as a regulator of lipoprotein metabolism. Curr. Atheroscler. Rep. 14, 211-218
    • (2012) Curr. Atheroscler. Rep. , vol.14 , pp. 211-218
    • Strong, A.1    Rader, D.J.2
  • 35
    • 84876154662 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress induces hepatic steatosis via increased expression of the hepatic very low-density lipoprotein receptor
    • Jo, H., Choe, S. S., Shin, K. C., Jang, H., Lee, J. H., Seong, J. K., Back, S. H., and Kim, J. B. (2013) Endoplasmic reticulum stress induces hepatic steatosis via increased expression of the hepatic very low-density lipoprotein receptor. Hepatology 57, 1366-1377
    • (2013) Hepatology , vol.57 , pp. 1366-1377
    • Jo, H.1    Choe, S.S.2    Shin, K.C.3    Jang, H.4    Lee, J.H.5    Seong, J.K.6    Back, S.H.7    Kim, J.B.8
  • 36
    • 84878656191 scopus 로고    scopus 로고
    • Apolipoprotein C-III: Going back to the future for a lipid drug target
    • Huff, M. W., and Hegele, R. A. (2013) Apolipoprotein C-III: going back to the future for a lipid drug target. Circ. Res. 112, 1405-1408
    • (2013) Circ. Res. , vol.112 , pp. 1405-1408
    • Huff, M.W.1    Hegele, R.A.2
  • 38
    • 16244382558 scopus 로고    scopus 로고
    • Androgen receptor null male mice develop late-onset obesity caused by decreased energy expenditure and lipolytic activity but show normal insulin sensitivity with high adiponectin secretion
    • Fan, W., Yanase, T., Nomura, M., Okabe, T., Goto, K., Sato, T., Kawano, H., Kato, S., and Nawata, H. (2005) Androgen receptor null male mice develop late-onset obesity caused by decreased energy expenditure and lipolytic activity but show normal insulin sensitivity with high adiponectin secretion. Diabetes 54, 1000-1008
    • (2005) Diabetes , vol.54 , pp. 1000-1008
    • Fan, W.1    Yanase, T.2    Nomura, M.3    Okabe, T.4    Goto, K.5    Sato, T.6    Kawano, H.7    Kato, S.8    Nawata, H.9
  • 39
    • 20044369200 scopus 로고    scopus 로고
    • Insulin and leptin resistance with hyperleptinemia in mice lacking androgen receptor
    • Lin, H. Y., Xu, Q., Yeh, S., Wang, R. S., Sparks, J. D., and Chang, C. (2005) Insulin and leptin resistance with hyperleptinemia in mice lacking androgen receptor. Diabetes 54, 1717-1725
    • (2005) Diabetes , vol.54 , pp. 1717-1725
    • Lin, H.Y.1    Xu, Q.2    Yeh, S.3    Wang, R.S.4    Sparks, J.D.5    Chang, C.6
  • 41
    • 9144242999 scopus 로고    scopus 로고
    • Abnormal mammary gland development and growth retardation in female mice and MCF7 breast cancer cells lacking androgen receptor
    • Yeh, S., Hu, Y. C., Wang, P. H., Xie, C., Xu, Q., Tsai, M. Y., Dong, Z., Wang, R. S., Lee, T. H., and Chang, C. (2003) Abnormal mammary gland development and growth retardation in female mice and MCF7 breast cancer cells lacking androgen receptor. J. Exp. Med. 198, 1899-1908
    • (2003) J. Exp. Med. , vol.198 , pp. 1899-1908
    • Yeh, S.1    Hu, Y.C.2    Wang, P.H.3    Xie, C.4    Xu, Q.5    Tsai, M.Y.6    Dong, Z.7    Wang, R.S.8    Lee, T.H.9    Chang, C.10
  • 42
    • 34547093857 scopus 로고    scopus 로고
    • Female mice haploinsufficient for an inactivated androgen receptor (AR) exhibit age-dependent defects that resemble the AR null phenotype of dysfunctional late follicle development, ovulation, and fertility
    • Walters, K. A., Allan, C. M., Jimenez, M., Lim, P. R., Davey, R. A., Zajac, J. D., Illingworth, P., and Handelsman, D. J. (2007) Female mice haploinsufficient for an inactivated androgen receptor (AR) exhibit age-dependent defects that resemble the AR null phenotype of dysfunctional late follicle development, ovulation, and fertility. Endocrinology 148, 3674-3684
    • (2007) Endocrinology , vol.148 , pp. 3674-3684
    • Walters, K.A.1    Allan, C.M.2    Jimenez, M.3    Lim, P.R.4    Davey, R.A.5    Zajac, J.D.6    Illingworth, P.7    Handelsman, D.J.8
  • 46
    • 84860548566 scopus 로고    scopus 로고
    • Deletion of the androgen receptor in adipose tissue in male mice elevates retinol binding protein 4 and reveals independent effects on visceral fat mass and on glucose homeostasis
    • McInnes, K. J., Smith, L. B., Hunger, N. I., Saunders, P. T., Andrew, R., and Walker, B. R. (2012) Deletion of the androgen receptor in adipose tissue in male mice elevates retinol binding protein 4 and reveals independent effects on visceral fat mass and on glucose homeostasis. Diabetes 61, 1072-1081
    • (2012) Diabetes , vol.61 , pp. 1072-1081
    • McInnes, K.J.1    Smith, L.B.2    Hunger, N.I.3    Saunders, P.T.4    Andrew, R.5    Walker, B.R.6
  • 47
    • 42449107820 scopus 로고    scopus 로고
    • Hyperleptinemia without obesity in male mice lacking androgen receptor in adipose tissue
    • Yu, I. C., Lin, H. Y., Liu, N. C., Wang, R. S., Sparks, J. D., Yeh, S., and Chang, C. (2008) Hyperleptinemia without obesity in male mice lacking androgen receptor in adipose tissue. Endocrinology 149, 2361-2368
    • (2008) Endocrinology , vol.149 , pp. 2361-2368
    • Yu, I.C.1    Lin, H.Y.2    Liu, N.C.3    Wang, R.S.4    Sparks, J.D.5    Yeh, S.6    Chang, C.7
  • 48
    • 0027491348 scopus 로고
    • Steroidal regulation of biologically active luteinizing hormone secretion in men and women
    • Veldhuis, J. D., and Dufau, M. L. (1993) Steroidal regulation of biologically active luteinizing hormone secretion in men and women. Hum. Reprod. 8(Suppl 2), 84-96
    • (1993) Hum. Reprod. , vol.8 , pp. 84-96
    • Veldhuis, J.D.1    Dufau, M.L.2
  • 49
    • 38049077991 scopus 로고    scopus 로고
    • Metformin for the treatment of the polycystic ovary syndrome
    • Nestler, J. E. (2008) Metformin for the treatment of the polycystic ovary syndrome. N. Engl. J. Med. 358, 47-54
    • (2008) N. Engl. J. Med. , vol.358 , pp. 47-54
    • Nestler, J.E.1
  • 51
    • 0036498976 scopus 로고    scopus 로고
    • Endogenous postmenopausal hormones and carotid atherosclerosis: A case-control study of the atherosclerosis risk in communities cohort
    • Golden, S. H., Maguire, A., Ding, J., Crouse, J. R., Cauley, J. A., Zacur, H., and Szklo, M. (2002) Endogenous postmenopausal hormones and carotid atherosclerosis: a case-control study of the atherosclerosis risk in communities cohort. Am. J. Epidemiol. 155, 437-445
    • (2002) Am. J. Epidemiol. , vol.155 , pp. 437-445
    • Golden, S.H.1    Maguire, A.2    Ding, J.3    Crouse, J.R.4    Cauley, J.A.5    Zacur, H.6    Szklo, M.7
  • 52
    • 0037212783 scopus 로고    scopus 로고
    • The association of lower testosterone level with coronary artery disease in postmenopausal women
    • Kaczmarek, A., Reczuch, K., Majda, J., Banasiak, W., and Ponikowski, P. (2003) The association of lower testosterone level with coronary artery disease in postmenopausal women. Int. J. Cardiol. 87, 53-57
    • (2003) Int. J. Cardiol. , vol.87 , pp. 53-57
    • Kaczmarek, A.1    Reczuch, K.2    Majda, J.3    Banasiak, W.4    Ponikowski, P.5
  • 54
    • 76149108405 scopus 로고    scopus 로고
    • Extremes of endogenous testosterone are associated with increased risk of incident coronary events in older women
    • Laughlin, G. A., Goodell, V., and Barrett-Connor, E. (2010) Extremes of endogenous testosterone are associated with increased risk of incident coronary events in older women. J. Clin. Endocrinol. Metab. 95, 740-747
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , pp. 740-747
    • Laughlin, G.A.1    Goodell, V.2    Barrett-Connor, E.3
  • 56
    • 77957174207 scopus 로고    scopus 로고
    • Low testosterone levels predict all-cause mortality and cardiovascular events in women: A prospective cohort study in German primary care patients
    • Sievers, C., Klotsche, J., Pieper, L., Schneider, H. J., März, W., Wittchen, H. U., Stalla, G. K., and Mantzoros, C. (2010) Low testosterone levels predict all-cause mortality and cardiovascular events in women: a prospective cohort study in German primary care patients. Eur. J. Endocrinol. 163, 699-708
    • (2010) Eur. J. Endocrinol. , vol.163 , pp. 699-708
    • Sievers, C.1    Klotsche, J.2    Pieper, L.3    Schneider, H.J.4    März, W.5    Wittchen, H.U.6    Stalla, G.K.7    Mantzoros, C.8
  • 57
    • 67649717981 scopus 로고    scopus 로고
    • The effects of endogenous and exogenous androgens on cardiovascular disease risk factors and progression
    • Manolakou, P., Angelopoulou, R., Bakoyiannis, C., and Bastounis, E. (2009) The effects of endogenous and exogenous androgens on cardiovascular disease risk factors and progression. Reprod. Biol. Endocrinol. 7, 44
    • (2009) Reprod. Biol. Endocrinol. , vol.7 , pp. 44
    • Manolakou, P.1    Angelopoulou, R.2    Bakoyiannis, C.3    Bastounis, E.4


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