메뉴 건너뛰기




Volumn 24, Issue 13, 2015, Pages 1546-1557

All the Tested Human Somatic Cells Express Both Oct4A and Its Pseudogenes but Express Oct4A at Much Lower Levels Compared with Its Pseudogenes and Human Embryonic Stem Cells

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 4; OCTAMER TRANSCRIPTION FACTOR 4 PG1; OCTAMER TRANSCRIPTION FACTOR 4 PG3; OCTAMER TRANSCRIPTION FACTOR 4 PG4; OCTAMER TRANSCRIPTION FACTOR 4A; UNCLASSIFIED DRUG; POU5F1 PROTEIN, HUMAN;

EID: 84931292389     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2014.0552     Document Type: Article
Times cited : (16)

References (75)
  • 1
    • 77953566957 scopus 로고    scopus 로고
    • Concise review: Isoforms of OCT4 contribute to the confusing diversity in stem cell biology
    • Wang X and J Dai. (2010). Concise review: isoforms of OCT4 contribute to the confusing diversity in stem cell biology. Stem Cells 28:885-893.
    • (2010) Stem Cells , vol.28 , pp. 885-893
    • Wang, X.1    Dai, J.2
  • 2
    • 33846000940 scopus 로고    scopus 로고
    • POU5F1 isoforms show different expression patterns in human embryonic stem cells and preimplantation embryos
    • Cauffman G, I Liebaers, A Van Steirteghem and H Van De Velde. (2006). POU5F1 isoforms show different expression patterns in human embryonic stem cells and preimplantation embryos. Stem Cells 24:2685-2691.
    • (2006) Stem Cells , vol.24 , pp. 2685-2691
    • Cauffman, G.1    Liebaers, I.2    Van Steirteghem, A.3    Van De Velde, H.4
  • 4
    • 33845930820 scopus 로고    scopus 로고
    • The human OCT-4 isoforms differ in their ability to confer self-renewal
    • Lee J, HK Kim, JY Rho, YM Han and J Kim. (2006). The human OCT-4 isoforms differ in their ability to confer self-renewal. J Biol Chem 281:33554-33565.
    • (2006) J Biol Chem , vol.281 , pp. 33554-33565
    • Lee, J.1    Kim, H.K.2    Rho, J.Y.3    Han, Y.M.4    Kim, J.5
  • 6
    • 67649612847 scopus 로고    scopus 로고
    • Alternative translation of OCT4 by an internal ribosome entry site and its novel function in stress response
    • Wang X, Y Zhao, Z Xiao, B Chen, Z Wei, B Wang, J Zhang, J Han, Y Gao, et al. (2009). Alternative translation of OCT4 by an internal ribosome entry site and its novel function in stress response. Stem Cells 27:1265-1275.
    • (2009) Stem Cells , vol.27 , pp. 1265-1275
    • Wang, X.1    Zhao, Y.2    Xiao, Z.3    Chen, B.4    Wei, Z.5    Wang, B.6    Zhang, J.7    Han, J.8    Gao, Y.9
  • 7
    • 79960846727 scopus 로고    scopus 로고
    • OCT4B1, a novel spliced variant of OCT4, generates a stable truncated protein with a potential role in stress response
    • Farashahi Yazd E, MR Rafiee, M Soleimani, M Tavallaei, MK Salmani and SJ Mowla. (2011). OCT4B1, a novel spliced variant of OCT4, generates a stable truncated protein with a potential role in stress response. Cancer Lett 309:170-175.
    • (2011) Cancer Lett , vol.309 , pp. 170-175
    • Farashahi Yazd, E.1    Rafiee, M.R.2    Soleimani, M.3    Tavallaei, M.4    Salmani, M.K.5    Mowla, S.J.6
  • 8
    • 77955064503 scopus 로고    scopus 로고
    • The novel OCT4 spliced variant OCT4B1 can generate three protein isoforms by alternative splicing into OCT4B
    • Gao Y, X Wang, J Han, Z Xiao, B Chen, G Su and J Dai. (2010). The novel OCT4 spliced variant OCT4B1 can generate three protein isoforms by alternative splicing into OCT4B. J Genet Genomics 37:461-465.
    • (2010) J Genet Genomics , vol.37 , pp. 461-465
    • Gao, Y.1    Wang, X.2    Han, J.3    Xiao, Z.4    Chen, B.5    Su, G.6    Dai, J.7
  • 9
    • 58149329044 scopus 로고    scopus 로고
    • The POU5F1P1 pseudogene encodes a putative protein similar to POU5F1 isoform 1
    • Panagopoulos I, E Möller, A Collin and F Mertens. (2008). The POU5F1P1 pseudogene encodes a putative protein similar to POU5F1 isoform 1. Oncol Rep 20:1029-1033.
    • (2008) Oncol Rep , vol.20 , pp. 1029-1033
    • Panagopoulos, I.1    Möller, E.2    Collin, A.3    Mertens, F.4
  • 11
    • 79952550805 scopus 로고    scopus 로고
    • Expression of OCT4 pseudogenes in human tumours: Lessons from glioma and breast carcinoma
    • Zhao S, Q Yuan, H Hao, Y Guo, S Liu, Y Zhang, J Wang, H Liu, F Wang, et al. (2011). Expression of OCT4 pseudogenes in human tumours: lessons from glioma and breast carcinoma. J Pathol 223:672-682.
    • (2011) J Pathol , vol.223 , pp. 672-682
    • Zhao, S.1    Yuan, Q.2    Hao, H.3    Guo, Y.4    Liu, S.5    Zhang, Y.6    Wang, J.7    Liu, H.8    Wang, F.9
  • 13
    • 34047169674 scopus 로고    scopus 로고
    • Stem cell marker OCT3/4 in tumor biology and germ cell tumor diagnostics: History and future
    • de Jong J and LH Looijenga. (2006). Stem cell marker OCT3/4 in tumor biology and germ cell tumor diagnostics: history and future. Crit Rev Oncog 12:171-203.
    • (2006) Crit Rev Oncog , vol.12 , pp. 171-203
    • De Jong, J.1    Looijenga, L.H.2
  • 15
    • 84861874664 scopus 로고    scopus 로고
    • Mesenchymal stem cells
    • Rankin S. (2012). Mesenchymal stem cells. Thorax 67: 565-566.
    • (2012) Thorax , vol.67 , pp. 565-566
    • Rankin, S.1
  • 16
    • 84880939440 scopus 로고    scopus 로고
    • New methods for inducing the differentiation of amniotic-derived mesenchymal stem cells into motor neuron precursor cells
    • Hu W, FX Guan, Y Li, YJ Tang, F Yang and B Yang. (2013). New methods for inducing the differentiation of amniotic-derived mesenchymal stem cells into motor neuron precursor cells. Tissue Cell 45:295-305.
    • (2013) Tissue Cell , vol.45 , pp. 295-305
    • Hu, W.1    Guan, F.X.2    Li, Y.3    Tang, Y.J.4    Yang, F.5    Yang, B.6
  • 17
    • 84898972471 scopus 로고    scopus 로고
    • Comparison of phenotypic markers and neural differentiation potential of multipotent adult progenitor cells and mesenchymal stem cells
    • Singh SP, NK Tripathy and S Nityanand. (2013). Comparison of phenotypic markers and neural differentiation potential of multipotent adult progenitor cells and mesenchymal stem cells. World J Stem Cells 5:53-60.
    • (2013) World J Stem Cells , vol.5 , pp. 53-60
    • Singh, S.P.1    Tripathy, N.K.2    Nityanand, S.3
  • 20
    • 84869433016 scopus 로고    scopus 로고
    • Increased SCF/c-kit by hypoxia promotes autophagy of human placental chorionic plate-derived mesenchymal stem cells via regulating the phosphorylation of mTOR
    • Lee Y, J Jung, KJ Cho, SK Lee, KW Park, IH Oh and GJ Kim. (2013). Increased SCF/c-kit by hypoxia promotes autophagy of human placental chorionic plate-derived mesenchymal stem cells via regulating the phosphorylation of mTOR. J Cell Biochem 114:79-88.
    • (2013) J Cell Biochem , vol.114 , pp. 79-88
    • Lee, Y.1    Jung, J.2    Cho, K.J.3    Lee, S.K.4    Park, K.W.5    Oh, I.H.6    Kim, G.J.7
  • 21
    • 84873714138 scopus 로고    scopus 로고
    • Stemness and angiogenic gene expression changes of serial-passage human amnion mesenchymal cells
    • Fatimah SS, GC Tan, K Chua, MM Nur Fariha, AE Tan and AR Hayati. (2013). Stemness and angiogenic gene expression changes of serial-passage human amnion mesenchymal cells. Microvasc Res 86:21-29.
    • (2013) Microvasc Res , vol.86 , pp. 21-29
    • Fatimah, S.S.1    Tan, G.C.2    Chua, K.3    Nur Fariha, M.M.4    Tan, A.E.5    Hayati, A.R.6
  • 23
    • 84884254131 scopus 로고    scopus 로고
    • Human bone marrow-derived mesenchymal stem cell gene expression patterns vary with culture conditions
    • Lee MW, DS Kim, KH Yoo, HR Kim, IK Jang, IH Lee, SY Kim, MH Son, SH Lee, et al. (2013). Human bone marrow-derived mesenchymal stem cell gene expression patterns vary with culture conditions. Blood Res 48:107-114.
    • (2013) Blood Res , vol.48 , pp. 107-114
    • Lee, M.W.1    Kim, D.S.2    Yoo, K.H.3    Kim, H.R.4    Jang, I.K.5    Lee, I.H.6    Kim, S.Y.7    Son, M.H.8    Lee, S.H.9
  • 24
    • 84864304203 scopus 로고    scopus 로고
    • Oct4 and Nanog directly regulate Dnmt1 to maintain self-renewal and undifferentiated state in mesenchymal stem cells
    • Tsai CC, PF Su, YF Huang, TL Yew and SC Hung. (2012). Oct4 and Nanog directly regulate Dnmt1 to maintain self-renewal and undifferentiated state in mesenchymal stem cells. Mol Cell 47:169-182.
    • (2012) Mol Cell , vol.47 , pp. 169-182
    • Tsai, C.C.1    Su, P.F.2    Huang, Y.F.3    Yew, T.L.4    Hung, S.C.5
  • 25
    • 84862807558 scopus 로고    scopus 로고
    • Basic fibroblast growth factor enhances stemness of human stem cells from the apical papilla
    • Wu J, GT Huang, WX He, P Wang, ZC Tong, Q Jia, LP Dong, ZY Niu and LX Ni. (2012). Basic fibroblast growth factor enhances stemness of human stem cells from the apical papilla. J Endod 38:614-622.
    • (2012) J Endod , vol.38 , pp. 614-622
    • Wu, J.1    Huang, G.T.2    He, W.X.3    Wang, P.4    Tong, Z.C.5    Jia, Q.6    Dong, L.P.7    Niu, Z.Y.8    Ni, L.X.9
  • 28
    • 84857490219 scopus 로고    scopus 로고
    • Inhibition of platelet-derived growth factor receptor signaling regulates Oct4 and Nanog expression, cell shape, and mesenchymal stem cell potency
    • Ball SG, A Shuttleworth and CM Kielty. (2012). Inhibition of platelet-derived growth factor receptor signaling regulates Oct4 and Nanog expression, cell shape, and mesenchymal stem cell potency. Stem Cells 30:548-560.
    • (2012) Stem Cells , vol.30 , pp. 548-560
    • Ball, S.G.1    Shuttleworth, A.2    Kielty, C.M.3
  • 29
    • 79960269489 scopus 로고    scopus 로고
    • Characterization and comparison of telomere length, telomerase and reverse transcriptase activity and gene expression in human mesenchymal stem cells and cancer cells of various origins
    • Jeon BG, BM Kumar, EJ Kang, SA Ock, SL Lee, DO Kwack, JH Byun, BW Park and GJ Rho. (2011). Characterization and comparison of telomere length, telomerase and reverse transcriptase activity and gene expression in human mesenchymal stem cells and cancer cells of various origins. Cell Tissue Res 345:149-161.
    • (2011) Cell Tissue Res , vol.345 , pp. 149-161
    • Jeon, B.G.1    Kumar, B.M.2    Kang, E.J.3    Ock, S.A.4    Lee, S.L.5    Kwack, D.O.6    Byun, J.H.7    Park, B.W.8    Rho, G.J.9
  • 30
    • 79959849772 scopus 로고    scopus 로고
    • Analysis of the chondrogenic potential and secretome of mesenchymal stem cells derived from human umbilical cord stroma
    • Arufe MC, A De la Fuente, J Mateos, I Fuentes, FJ De Toro and FJ Blanco. (2010). Analysis of the chondrogenic potential and secretome of mesenchymal stem cells derived from human umbilical cord stroma. Stem Cells Dev 20: 1199-1212.
    • (2010) Stem Cells Dev , vol.20 , pp. 1199-1212
    • Arufe, M.C.1    De La Fuente, A.2    Mateos, J.3    Fuentes, I.4    De Toro, F.J.5    Blanco, F.J.6
  • 32
    • 79951795484 scopus 로고    scopus 로고
    • A comprehensive characterization study of human bone marrow mscs with an emphasis on molecular and ultrastructural properties
    • Karaöz E, A Okçu, G Gacar, S Yürüker, Ö Saʇlam and H Kenar. (2011). A comprehensive characterization study of human bone marrow mscs with an emphasis on molecular and ultrastructural properties. J Cell Physiol 226:1367-1382.
    • (2011) J Cell Physiol , vol.226 , pp. 1367-1382
    • Karaöz, E.1    Okçu, A.2    Gacar, G.3    Yürüker, S.4    Saʇlam, Ö.5    Kenar, H.6
  • 34
    • 74649085138 scopus 로고    scopus 로고
    • Embryonic stem cell marker expression pattern in human mesenchymal stem cells derived from bone marrow, adipose tissue, heart and dermis
    • Riekstina U, I Cakstina, V Parfejevs, M Hoogduijn, G Jankovskis, I Muiznieks, R Muceniece and J Ancans. (2009). Embryonic stem cell marker expression pattern in human mesenchymal stem cells derived from bone marrow, adipose tissue, heart and dermis. Stem Cell Rev 5:378-386.
    • (2009) Stem Cell Rev , vol.5 , pp. 378-386
    • Riekstina, U.1    Cakstina, I.2    Parfejevs, V.3    Hoogduijn, M.4    Jankovskis, G.5    Muiznieks, I.6    Muceniece, R.7    Ancans, J.8
  • 35
    • 40949096438 scopus 로고    scopus 로고
    • Equine umbilical cord blood contains a population of stem cells that express Oct4 and differentiate into mesodermal and endodermal cell types
    • Reed SA and SE Johnson. (2008). Equine umbilical cord blood contains a population of stem cells that express Oct4 and differentiate into mesodermal and endodermal cell types. J Cell Physiol 215:329-336.
    • (2008) J Cell Physiol , vol.215 , pp. 329-336
    • Reed, S.A.1    Johnson, S.E.2
  • 36
    • 55049085582 scopus 로고    scopus 로고
    • In vivo osteoprogenitor potency of human stromal cells from different tissues does not correlate with expression of POU5F1 or its pseudogenes
    • Kaltz N, A Funari, S Hippauf, B Delorme, D Noël, M Riminucci, VR Jacobs, T Häupl, C Jorgensen, et al. (2008). In vivo osteoprogenitor potency of human stromal cells from different tissues does not correlate with expression of POU5F1 or its pseudogenes. Stem Cells 26: 2419-2424.
    • (2008) Stem Cells , vol.26 , pp. 2419-2424
    • Kaltz, N.1    Funari, A.2    Hippauf, S.3    Delorme, B.4    Noël, D.5    Riminucci, M.6    Jacobs, V.R.7    Häupl, T.8    Jorgensen, C.9
  • 37
    • 37549009470 scopus 로고    scopus 로고
    • Molecular and proteomic characterization of human mesenchymal stem cells derived from amniotic fluid: Comparison to bone marrow mesenchymal stem cells
    • Roubelakis MG, KI Pappa, V Bitsika, D Zagoura, A Vlahou, HA Papadaki, A Antsaklis and NP Anagnou. (2007). Molecular and proteomic characterization of human mesenchymal stem cells derived from amniotic fluid: comparison to bone marrow mesenchymal stem cells. Stem Cells Dev 16:931-952.
    • (2007) Stem Cells Dev , vol.16 , pp. 931-952
    • Roubelakis, M.G.1    Pappa, K.I.2    Bitsika, V.3    Zagoura, D.4    Vlahou, A.5    Papadaki, H.A.6    Antsaklis, A.7    Anagnou, N.P.8
  • 38
    • 25444432287 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from CD133- positive cells in mobilized peripheral blood and cord blood: Proliferation, Oct4 expression, and plasticity
    • Tondreau T, N Meuleman, A Delforge, M Dejeneffe, R Leroy, M Massy, C Mortier, D Bron and L Lagneaux. (2005). Mesenchymal stem cells derived from CD133- positive cells in mobilized peripheral blood and cord blood: proliferation, Oct4 expression, and plasticity. Stem Cells 23:1105-1112.
    • (2005) Stem Cells , vol.23 , pp. 1105-1112
    • Tondreau, T.1    Meuleman, N.2    Delforge, A.3    Dejeneffe, M.4    Leroy, R.5    Massy, M.6    Mortier, C.7    Bron, D.8    Lagneaux, L.9
  • 39
    • 3042634774 scopus 로고    scopus 로고
    • Isolation of human multipotent mesenchymal stem cells from second-trimester amniotic fluid using a novel two-stage culture protocol
    • Tsai MS, Lee JL, Chang YJ and SM Hwang. (2004). Isolation of human multipotent mesenchymal stem cells from second-trimester amniotic fluid using a novel two-stage culture protocol. Hum Reprod 19:1450-1456.
    • (2004) Hum Reprod , vol.19 , pp. 1450-1456
    • Tsai, M.S.1    Lee, J.L.2    Chang, Y.J.3    Hwang, S.M.4
  • 40
    • 84896064882 scopus 로고    scopus 로고
    • Expression and differentiation between OCT4A and its pseudogenes in human ESCs and differentiated adult somatic cells
    • Jez M, S Ambady, O Kashpur, A Grella, C Malcuit, L Vilner, P Rozman and T Dominko. (2014). Expression and differentiation between OCT4A and its pseudogenes in human ESCs and differentiated adult somatic cells. PLoS One 9:e89546.
    • (2014) PLoS One , vol.9
    • Jez, M.1    Ambady, S.2    Kashpur, O.3    Grella, A.4    Malcuit, C.5    Vilner, L.6    Rozman, P.7    Dominko, T.8
  • 41
    • 84884562854 scopus 로고    scopus 로고
    • Differential expression of Oct4 variants and pseudogenes in normal urothelium and urothelial cancer
    • Wezel F, J Pearson, LA Kirkwood and J Southgate. (2013). Differential expression of Oct4 variants and pseudogenes in normal urothelium and urothelial cancer. Am J Pathol 183:1128-1136.
    • (2013) Am J Pathol , vol.183 , pp. 1128-1136
    • Wezel, F.1    Pearson, J.2    Kirkwood, L.A.3    Southgate, J.4
  • 42
    • 84870424158 scopus 로고    scopus 로고
    • OCT4 pseudogenes present in human leukemia cells
    • Guo X and Y Tang. (2012). OCT4 pseudogenes present in human leukemia cells. Clin Exp Med 12:207-216.
    • (2012) Clin Exp Med , vol.12 , pp. 207-216
    • Guo, X.1    Tang, Y.2
  • 43
    • 77950441754 scopus 로고    scopus 로고
    • Human haematopoietic stem cells express Oct4 pseudogenes and lack the ability to initiate Oct4 promoter-driven gene expression
    • Redshaw Z and AJ Strain. (2010). Human haematopoietic stem cells express Oct4 pseudogenes and lack the ability to initiate Oct4 promoter-driven gene expression. J Negat Results Biomed 9:2-9.
    • (2010) J Negat Results Biomed , vol.9 , pp. 2-9
    • Redshaw, Z.1    Strain, A.J.2
  • 44
    • 84881611043 scopus 로고    scopus 로고
    • Unravelling the pluripotency paradox in fetal and placental mesenchymal stem cells: Oct-4 expression and the case of The Emperor's New Clothes
    • Ryan JM, AR Pettit, PV Guillot, JK Chan and NM Fisk. (2013). Unravelling the pluripotency paradox in fetal and placental mesenchymal stem cells: Oct-4 expression and the case of The Emperor's New Clothes. Stem Cell Rev 9:408-421.
    • (2013) Stem Cell Rev , vol.9 , pp. 408-421
    • Ryan, J.M.1    Pettit, A.R.2    Guillot, P.V.3    Chan, J.K.4    Fisk, N.M.5
  • 46
    • 78650254543 scopus 로고    scopus 로고
    • Ascorbic acid induces in vitro proliferation of human subcutaneous adipose tissue derived mesenchymal stem cells with upregulation of embryonic stem cell pluripotency markers Oct4 and SOX 2
    • Potdar PD and SB D'Souza. (2010). Ascorbic acid induces in vitro proliferation of human subcutaneous adipose tissue derived mesenchymal stem cells with upregulation of embryonic stem cell pluripotency markers Oct4 and SOX 2. Hum Cell 23:152-155.
    • (2010) Hum Cell , vol.23 , pp. 152-155
    • Potdar, P.D.1    D'Souza, S.B.2
  • 47
    • 72949122798 scopus 로고    scopus 로고
    • Chromatin states of core pluripotency-associated genes in pluripotent, multipotent and differentiated cells
    • Barrand S and P Collas. (2010). Chromatin states of core pluripotency-associated genes in pluripotent, multipotent and differentiated cells. Biochem Biophys Res Commun 391:762-767.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 762-767
    • Barrand, S.1    Collas, P.2
  • 48
    • 66149126375 scopus 로고    scopus 로고
    • Effects of ectopic Nanog and Oct4 overexpression on mesenchymal stem cells
    • Liu TM, YN Wu, XM Guo, JH Hui, EH Lee and B Lim. (2009). Effects of ectopic Nanog and Oct4 overexpression on mesenchymal stem cells. Stem Cells Dev 18:1013-1022.
    • (2009) Stem Cells Dev , vol.18 , pp. 1013-1022
    • Liu, T.M.1    Wu, Y.N.2    Guo, X.M.3    Hui, J.H.4    Lee, E.H.5    Lim, B.6
  • 49
    • 59349114878 scopus 로고    scopus 로고
    • Analysis of OCT4 expression in an extended panel of human tumor cell lines from multiple entities and in human mesenchymal stem cells
    • Mueller T, J Luetzkendorf, K Nerger, HJ Schmoll and LP Mueller. (2009). Analysis of OCT4 expression in an extended panel of human tumor cell lines from multiple entities and in human mesenchymal stem cells. Cell Mol Life Sci 66:495-503.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 495-503
    • Mueller, T.1    Luetzkendorf, J.2    Nerger, K.3    Schmoll, H.J.4    Mueller, L.P.5
  • 51
    • 84862815896 scopus 로고    scopus 로고
    • Differentiation of umbilical cord mesenchymal stem cells into steroidogenic cells in comparison with bone marrow mesenchymal stem cells
    • Wei X, GF Peng, SB Zheng and XJ Wu. (2012). Differentiation of umbilical cord mesenchymal stem cells into steroidogenic cells in comparison with bone marrow mesenchymal stem cells. Cell Prolif 45:101-110.
    • (2012) Cell Prolif , vol.45 , pp. 101-110
    • Wei, X.1    Peng, G.F.2    Zheng, S.B.3    Wu, X.J.4
  • 52
    • 84876230050 scopus 로고    scopus 로고
    • Forced expression of OCT4 influences the expression of pluripotent genes in human mesenchymal stem cells and fibroblasts
    • Palma CS, MA Tannous, TM Malta, EM Russo, DT Covas and V Picanco-Castro. (2013). Forced expression of OCT4 influences the expression of pluripotent genes in human mesenchymal stem cells and fibroblasts. Genet Mol Res 12:1054-1060.
    • (2013) Genet Mol Res , vol.12 , pp. 1054-1060
    • Palma, C.S.1    Tannous, M.A.2    Malta, T.M.3    Russo, E.M.4    Covas, D.T.5    Picanco-Castro, V.6
  • 53
    • 37349051446 scopus 로고    scopus 로고
    • Functional similarities among genes regulated by OCT4 in human mesenchymal and embryonic stem cells
    • Greco SJ, K Liu and P Rameshwar. (2007). Functional similarities among genes regulated by OCT4 in human mesenchymal and embryonic stem cells. Stem Cells 25: 3143-3154.
    • (2007) Stem Cells , vol.25 , pp. 3143-3154
    • Greco, S.J.1    Liu, K.2    Rameshwar, P.3
  • 54
    • 84907821783 scopus 로고    scopus 로고
    • Effect of ectopic OCT4 expression on canine adipose tissue-derived mesenchymal stem cell proliferation
    • Han SH, G Jang, BK Bae, SM Han, YR Koh, JO Ahn, WS Jung, SK Kang, JC Ra, et al. (2014). Effect of ectopic OCT4 expression on canine adipose tissue-derived mesenchymal stem cell proliferation. Cell Biol Int 38:1163-1173.
    • (2014) Cell Biol Int , vol.38 , pp. 1163-1173
    • Han, S.H.1    Jang, G.2    Bae, B.K.3    Han, S.M.4    Koh, Y.R.5    Ahn, J.O.6    Jung, W.S.7    Kang, S.K.8    Ra, J.C.9
  • 55
    • 70349501484 scopus 로고    scopus 로고
    • Regulation of adipose tissue stromal cells behaviors by endogenic Oct4 expression control
    • Kim JH, MK Jee, SY Lee, TH Han, BS Kim, KS Kang and SK Kang. (2009). Regulation of adipose tissue stromal cells behaviors by endogenic Oct4 expression control. PLoS One 4:e7166.
    • (2009) PLoS One , vol.4
    • Kim, J.H.1    Jee, M.K.2    Lee, S.Y.3    Han, T.H.4    Kim, B.S.5    Kang, K.S.6    Kang, S.K.7
  • 56
    • 84908065087 scopus 로고    scopus 로고
    • Concurrent expression of Oct4 and Nanog maintains mesenchymal stem-like property of human dental pulp cells
    • Huang CE, FW Hu, CH Yu, LL Tsai, TH Lee, MY Chou and CC Yu. (2014). Concurrent expression of Oct4 and Nanog maintains mesenchymal stem-like property of human dental pulp cells. Int J Mol Sci 15:18623-18639.
    • (2014) Int J Mol Sci , vol.15 , pp. 18623-18639
    • Huang, C.E.1    Hu, F.W.2    Yu, C.H.3    Tsai, L.L.4    Lee, T.H.5    Chou, M.Y.6    Yu, C.C.7
  • 57
    • 84861952028 scopus 로고    scopus 로고
    • Effect of neuronal induction on NSE, Tau, and Oct4 promoter methylation in bone marrow mesenchymal stem cells
    • Duan P, Y Zhang, X Han, J Liu, W Yan and Y Xing. (2012). Effect of neuronal induction on NSE, Tau, and Oct4 promoter methylation in bone marrow mesenchymal stem cells. In Vitro Cell Dev Biol Anim 48:251-258.
    • (2012) In Vitro Cell Dev Biol Anim , vol.48 , pp. 251-258
    • Duan, P.1    Zhang, Y.2    Han, X.3    Liu, J.4    Yan, W.5    Xing, Y.6
  • 58
    • 78650389774 scopus 로고    scopus 로고
    • Co-expression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation
    • Chiou SH, ML Wang, YT Chou, CJ Chen, CF Hong, WJ Hsieh, HT Chang, YS Chen, TW Lin, et al. (2010). Co-expression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation. Cancer Res 70:10433-10444.
    • (2010) Cancer Res , vol.70 , pp. 10433-10444
    • Chiou, S.H.1    Wang, M.L.2    Chou, Y.T.3    Chen, C.J.4    Hong, C.F.5    Hsieh, W.J.6    Chang, H.T.7    Chen, Y.S.8    Lin, T.W.9
  • 59
    • 84882590291 scopus 로고    scopus 로고
    • OCT4 promotes tumorigenesis and inhibits apoptosis of cervical cancer cells by miR-125b/BAK1 pathway
    • Wang YD, N Cai, XL Wu, HZ Cao, LL Xie and PS Zheng. (2013). OCT4 promotes tumorigenesis and inhibits apoptosis of cervical cancer cells by miR-125b/BAK1 pathway. Cell Death Dis 4:e760.
    • (2013) Cell Death Dis , vol.4 , pp. e760
    • Wang, Y.D.1    Cai, N.2    Wu, X.L.3    Cao, H.Z.4    Xie, L.L.5    Zheng, P.S.6
  • 60
    • 84874101048 scopus 로고    scopus 로고
    • OCT4 increases BIRC5 and CCND1 expression and promotes cancer progression in hepatocellular carcinoma
    • Cao L, C Li, S Shen, Y Yan, W Ji, J Wang, H Qian, X Jiang, Z Li, et al. (2013). OCT4 increases BIRC5 and CCND1 expression and promotes cancer progression in hepatocellular carcinoma. BMC Cancer 13:82.
    • (2013) BMC Cancer , vol.13 , pp. 82
    • Cao, L.1    Li, C.2    Shen, S.3    Yan, Y.4    Ji, W.5    Wang, J.6    Qian, H.7    Jiang, X.8    Li, Z.9
  • 62
    • 53049104709 scopus 로고    scopus 로고
    • Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis
    • Hu T, S Liu, DR Breiter, F Wang, Y Tang and S Sun. (2008). Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis. Cancer Res 68:6533-6540.
    • (2008) Cancer Res , vol.68 , pp. 6533-6540
    • Hu, T.1    Liu, S.2    Breiter, D.R.3    Wang, F.4    Tang, Y.5    Sun, S.6
  • 63
    • 84857935029 scopus 로고    scopus 로고
    • Oct4 expression enhances features of cancer stem cells in a mouse model of breast cancer
    • Kim RJ and JS Nam. (2011). Oct4 expression enhances features of cancer stem cells in a mouse model of breast cancer. Lab Anim Res 27:147-152.
    • (2011) Lab Anim Res , vol.27 , pp. 147-152
    • Kim, R.J.1    Nam, J.S.2
  • 65
    • 66249129372 scopus 로고    scopus 로고
    • Oct4 is expressed in human gliomas and promotes colony formation in glioma cells
    • Du Z, D Jia, S Liu, F Wang, G Li, Y Zhang, X Cao, EA Ling and A Hao. (2009). Oct4 is expressed in human gliomas and promotes colony formation in glioma cells. Glia 57:724-733.
    • (2009) Glia , vol.57 , pp. 724-733
    • Du, Z.1    Jia, D.2    Liu, S.3    Wang, F.4    Li, G.5    Zhang, Y.6    Cao, X.7    Ling, E.A.8    Hao, A.9
  • 66
    • 84869807785 scopus 로고    scopus 로고
    • OCT4 positively regulates Survivin expression to promote cancer cell proliferation and leads to poor prognosis in esophageal squamous cell carcinoma
    • Li C, Y Yan, W Ji, L Bao, H Qian, L Chen, M Wu, H Chen, Z Li, et al. (2012). OCT4 positively regulates Survivin expression to promote cancer cell proliferation and leads to poor prognosis in esophageal squamous cell carcinoma. PLoS One 7:e49693.
    • (2012) PLoS One , vol.7
    • Li, C.1    Yan, Y.2    Ji, W.3    Bao, L.4    Qian, H.5    Chen, L.6    Wu, M.7    Chen, H.8    Li, Z.9
  • 67
    • 50949166635 scopus 로고    scopus 로고
    • Oct-3/4 expression reflects tumor progression and regulates motility of bladder cancer cells
    • Chang CC, GS Shieh, P Wu, CC Lin, AL Shiau and CL Wu. (2008). Oct-3/4 expression reflects tumor progression and regulates motility of bladder cancer cells. Cancer Res 68:6281-6291.
    • (2008) Cancer Res , vol.68 , pp. 6281-6291
    • Chang, C.C.1    Shieh, G.S.2    Wu, P.3    Lin, C.C.4    Shiau, A.L.5    Wu, C.L.6
  • 68
    • 84872832415 scopus 로고    scopus 로고
    • OCT4 regulates epithelial-mesenchymal transition and its knockdown inhibits colorectal cancer cell migration and invasion
    • Dai X, J Ge, X Wang, X Qian, C Zhang and X Li. (2013). OCT4 regulates epithelial-mesenchymal transition and its knockdown inhibits colorectal cancer cell migration and invasion. Oncol Rep 29:155-160.
    • (2013) Oncol Rep , vol.29 , pp. 155-160
    • Dai, X.1    Ge, J.2    Wang, X.3    Qian, X.4    Zhang, C.5    Li, X.6
  • 69
    • 0344063368 scopus 로고    scopus 로고
    • Oct-3/4 is a dose-dependent oncogenic fate determinant
    • Gidekel S, G Pizov, Y Bergman and E Pikarsky. (2003). Oct-3/4 is a dose-dependent oncogenic fate determinant. Cancer Cell 4:361-370.
    • (2003) Cancer Cell , vol.4 , pp. 361-370
    • Gidekel, S.1    Pizov, G.2    Bergman, Y.3    Pikarsky, E.4
  • 71
    • 18844392836 scopus 로고    scopus 로고
    • Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues
    • Hochedlinger K, Y Yamada, C Beard and R Jaenisch. (2005). Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell 121:465-477.
    • (2005) Cell , vol.121 , pp. 465-477
    • Hochedlinger, K.1    Yamada, Y.2    Beard, C.3    Jaenisch, R.4
  • 73
    • 79952488548 scopus 로고    scopus 로고
    • Transient expression of OCT4 is sufficient to allow human keratinocytes to change their differentiation pathway
    • Racila D, M Winter, M Said, A Tomanek-Chalkley, S Wiechert, RL Eckert and JR Bickenbach. (2011). Transient expression of OCT4 is sufficient to allow human keratinocytes to change their differentiation pathway. Gene Ther 18:294-303.
    • (2011) Gene Ther , vol.18 , pp. 294-303
    • Racila, D.1    Winter, M.2    Said, M.3    Tomanek-Chalkley, A.4    Wiechert, S.5    Eckert, R.L.6    Bickenbach, J.R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.