메뉴 건너뛰기




Volumn 6, Issue , 2015, Pages

Mitochondrial E3 ligase March5 maintains stemness of mouse ES cells via suppression of ERK signalling

Author keywords

[No Author keywords available]

Indexed keywords

MARCH5 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT IALPHA; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 4; MARCH5 PROTEIN, MOUSE; MITOCHONDRIAL PROTEIN; PRKAR1A PROTEIN, MOUSE; RAF PROTEIN; UBIQUITIN PROTEIN LIGASE;

EID: 84931291926     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8112     Document Type: Article
Times cited : (33)

References (46)
  • 1
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans, M. J. & Kaufman, M. H. Establishment in culture of pluripotential cells from mouse embryos. Nature 292, 154-156 (1981).
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 2
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • Martin, G. R. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl Acad. Sci. 78, 7634-7638 (1981).
    • (1981) Proc. Natl Acad. Sci. , vol.78 , pp. 7634-7638
    • Martin, G.R.1
  • 3
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson, J. A. et al. Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147 (1998).
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1
  • 5
    • 0024205842 scopus 로고
    • Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
    • Williams, R. L. et al. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 336, 684-687 (1988).
    • (1988) Nature , vol.336 , pp. 684-687
    • Williams, R.L.1
  • 6
    • 0344845415 scopus 로고    scopus 로고
    • BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
    • Ying, Q.-L., Nichols, J., Chambers, I. & Smith, A. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115, 281-292 (2003).
    • (2003) Cell , vol.115 , pp. 281-292
    • Ying, Q.-L.1    Nichols, J.2    Chambers, I.3    Smith, A.4
  • 7
    • 1242267927 scopus 로고    scopus 로고
    • Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
    • Sato, N., Meijer, L., Skaltsounis, L., Greengard, P. & Brivanlou, A. H. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat. Med. 10, 55-63 (2004).
    • (2004) Nat. Med. , vol.10 , pp. 55-63
    • Sato, N.1    Meijer, L.2    Skaltsounis, L.3    Greengard, P.4    Brivanlou, A.H.5
  • 8
    • 80052475509 scopus 로고    scopus 로고
    • Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells
    • Ten Berge, D. et al. Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells. Nat. Cell Biol. 13, 1070-1075 (2011).
    • (2011) Nat. Cell Biol. , vol.13 , pp. 1070-1075
    • Ten Berge, D.1
  • 9
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer, L. A. et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122, 947-956 (2005).
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.A.1
  • 10
    • 0033517123 scopus 로고    scopus 로고
    • STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
    • Matsuda, T. et al. STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. EMBO J. 18, 4261-4269 (1999).
    • (1999) EMBO J. , vol.18 , pp. 4261-4269
    • Matsuda, T.1
  • 11
    • 0032127977 scopus 로고    scopus 로고
    • Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
    • Niwa, H., Burdon, T., Chambers, I. & Smith, A. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev. 12, 2048-2060 (1998).
    • (1998) Genes Dev. , vol.12 , pp. 2048-2060
    • Niwa, H.1    Burdon, T.2    Chambers, I.3    Smith, A.4
  • 12
    • 0032582513 scopus 로고    scopus 로고
    • Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
    • Nichols, J. et al. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95, 379-391 (1998).
    • (1998) Cell , vol.95 , pp. 379-391
    • Nichols, J.1
  • 13
    • 0037227099 scopus 로고    scopus 로고
    • Multipotent cell lineages in early mouse development depend on SOX2 function
    • Avilion, A. A. et al. Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev. 17, 126-140 (2003).
    • (2003) Genes Dev. , vol.17 , pp. 126-140
    • Avilion, A.A.1
  • 14
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
    • Mitsui, K. et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113, 631-642 (2003).
    • (2003) Cell , vol.113 , pp. 631-642
    • Mitsui, K.1
  • 15
    • 0038143611 scopus 로고    scopus 로고
    • Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
    • Chambers, I. et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113, 643-655 (2003).
    • (2003) Cell , vol.113 , pp. 643-655
    • Chambers, I.1
  • 16
    • 37549002155 scopus 로고    scopus 로고
    • Nanog safeguards pluripotency and mediates germline development
    • Chambers, I. et al. Nanog safeguards pluripotency and mediates germline development. Nature 450, 1230-1234 (2007).
    • (2007) Nature , vol.450 , pp. 1230-1234
    • Chambers, I.1
  • 17
    • 33645381936 scopus 로고    scopus 로고
    • The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • Loh, Y.-H. et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat. Genet. 38, 431-440 (2006).
    • (2006) Nat. Genet. , vol.38 , pp. 431-440
    • Loh, Y.-H.1
  • 18
    • 21644434480 scopus 로고    scopus 로고
    • Transcriptional regulation of nanog by OCT4 and SOX2
    • Rodda, D. J. et al. Transcriptional regulation of nanog by OCT4 and SOX2. J. Biol. Chem. 280, 24731-24737 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 24731-24737
    • Rodda, D.J.1
  • 19
    • 70450270857 scopus 로고    scopus 로고
    • Oct4 and LIF/Stat3 additively induce Kruppel factors to sustain embryonic stem cell self-renewal
    • Hall, J. et al. Oct4 and LIF/Stat3 additively induce Kruppel factors to sustain embryonic stem cell self-renewal. Cell Stem Cell 5, 597-609 (2009).
    • (2009) Cell Stem Cell , vol.5 , pp. 597-609
    • Hall, J.1
  • 20
    • 54949147295 scopus 로고    scopus 로고
    • Kruppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs
    • Ema, M. et al. Kruppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs. Cell Stem Cell 3, 555-567 (2008).
    • (2008) Cell Stem Cell , vol.3 , pp. 555-567
    • Ema, M.1
  • 21
    • 40249093059 scopus 로고    scopus 로고
    • A core Klf circuitry regulates self-renewal of embryonic stem cells
    • Jiang, J. et al. A core Klf circuitry regulates self-renewal of embryonic stem cells. Nat. Cell Biol. 10, 353-360 (2008).
    • (2008) Nat. Cell Biol. , vol.10 , pp. 353-360
    • Jiang, J.1
  • 22
    • 73949112709 scopus 로고    scopus 로고
    • Mitochondrial ubiquitin ligase MITOL ubiquitinates mutant SOD1 and attenuates mutant SOD1-induced reactive oxygen species generation
    • Yonashiro, R. et al. Mitochondrial ubiquitin ligase MITOL ubiquitinates mutant SOD1 and attenuates mutant SOD1-induced reactive oxygen species generation. Mol. Biol. Cell 20, 4524-4530 (2009).
    • (2009) Mol. Biol. Cell , vol.20 , pp. 4524-4530
    • Yonashiro, R.1
  • 23
    • 34347398050 scopus 로고    scopus 로고
    • The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division
    • Karbowski, M., Neutzner, A. & Youle, R. J. The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division. J. Cell Biol. 178, 71-84 (2007).
    • (2007) J. Cell Biol. , vol.178 , pp. 71-84
    • Karbowski, M.1    Neutzner, A.2    Youle, R.J.3
  • 24
    • 76649142385 scopus 로고    scopus 로고
    • Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1
    • Park, Y.-Y. et al. Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1. J. Cell Sci. 123, 619-626 (2010).
    • (2010) J. Cell Sci. , vol.123 , pp. 619-626
    • Park, Y.-Y.1
  • 25
    • 79958042278 scopus 로고    scopus 로고
    • Mitochondrial ubiquitin ligase MARCH5 promotes TLR7 signaling by attenuating TANK action
    • Shi, H.-X. et al. Mitochondrial ubiquitin ligase MARCH5 promotes TLR7 signaling by attenuating TANK action. PLoS Pathog. 7, e1002057 (2011).
    • (2011) PLoS Pathog. , vol.7
    • Shi, H.-X.1
  • 26
    • 34447506228 scopus 로고    scopus 로고
    • Mutagenesis by retroviral insertion in chemical mutagengenerated quasi-haploid mammalian cells
    • Kim, S. O. et al. Mutagenesis by retroviral insertion in chemical mutagengenerated quasi-haploid mammalian cells. Biotechniques 42, 493 (2007).
    • (2007) Biotechniques , vol.42 , pp. 493
    • Kim, S.O.1
  • 27
    • 79958042278 scopus 로고    scopus 로고
    • Mitochondrial ubiquitin ligase MARCH5 promotes TLR7 signaling by attenuating TANK action
    • Shi, H. X. et al. Mitochondrial ubiquitin ligase MARCH5 promotes TLR7 signaling by attenuating TANK action. PLoS Pathog. 7, e1002057 (2011).
    • (2011) PLoS Pathog. , vol.7
    • Shi, H.X.1
  • 28
    • 0036236897 scopus 로고    scopus 로고
    • Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259
    • Dhillon, A. S. et al. Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259. Mol. Cell. Biol. 22, 3237-3246 (2002).
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 3237-3246
    • Dhillon, A.S.1
  • 29
    • 84890164818 scopus 로고    scopus 로고
    • Diverse roles of the ubiquitin system in NF-kappaB activation
    • Iwai, K. Diverse roles of the ubiquitin system in NF-kappaB activation. Biochim. Biophys. Acta 1843, 129-136 (2014).
    • (2014) Biochim. Biophys. Acta , vol.1843 , pp. 129-136
    • Iwai, K.1
  • 30
    • 84875231510 scopus 로고    scopus 로고
    • Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?
    • Nathan, J. A., Kim, H. T., Ting, L., Gygi, S. P. & Goldberg, A. L. Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? EMBO J. 32, 552-565 (2013).
    • (2013) EMBO J. , vol.32 , pp. 552-565
    • Nathan, J.A.1    Kim, H.T.2    Ting, L.3    Gygi, S.P.4    Goldberg, A.L.5
  • 31
    • 79960909253 scopus 로고    scopus 로고
    • Prediction of ubiquitination sites by using the composition of k-spaced amino acid pairs
    • Chen, Z. et al. Prediction of ubiquitination sites by using the composition of k-spaced amino acid pairs. PloS One 6, e22930 (2011).
    • (2011) PloS One , vol.6
    • Chen, Z.1
  • 32
    • 44349170450 scopus 로고    scopus 로고
    • The ground state of embryonic stem cell self-renewal
    • Ying, Q. L. et al. The ground state of embryonic stem cell self-renewal. Nature 453, 519-523 (2008).
    • (2008) Nature , vol.453 , pp. 519-523
    • Ying, Q.L.1
  • 33
    • 84867387161 scopus 로고    scopus 로고
    • Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal
    • Martello, G. et al. Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal. Cell Stem Cell 11, 491-504 (2012).
    • (2012) Cell Stem Cell , vol.11 , pp. 491-504
    • Martello, G.1
  • 35
    • 0032438571 scopus 로고    scopus 로고
    • Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation
    • Cheng, A. M. et al. Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation. Cell 95, 793-803 (1998).
    • (1998) Cell , vol.95 , pp. 793-803
    • Cheng, A.M.1
  • 36
    • 34548587064 scopus 로고    scopus 로고
    • FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment
    • Kunath, T. et al. FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment. Development 134, 2895-2902 (2007).
    • (2007) Development , vol.134 , pp. 2895-2902
    • Kunath, T.1
  • 37
    • 0028808183 scopus 로고
    • Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3
    • Yuan, H., Corbi, N., Basilico, C. & Dailey, L. Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3. Genes Dev. 9, 2635-2645 (1995).
    • (1995) Genes Dev. , vol.9 , pp. 2635-2645
    • Yuan, H.1    Corbi, N.2    Basilico, C.3    Dailey, L.4
  • 38
    • 79959950773 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation
    • Wray, J. et al. Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation. Nat. Cell Biol. 13, 838-845 (2011).
    • (2011) Nat. Cell Biol. , vol.13 , pp. 838-845
    • Wray, J.1
  • 39
    • 77954822251 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species mediate cardiomyocyte formation from embryonic stem cells in high glucose
    • Crespo, F. L., Sobrado, V. R., Gomez, L., Cervera, A. M. & McCreath, K. J. Mitochondrial reactive oxygen species mediate cardiomyocyte formation from embryonic stem cells in high glucose. Stem Cells 28, 1132-1142 (2010).
    • (2010) Stem Cells , vol.28 , pp. 1132-1142
    • Crespo, F.L.1    Sobrado, V.R.2    Gomez, L.3    Cervera, A.M.4    McCreath, K.J.5
  • 40
    • 77950523031 scopus 로고    scopus 로고
    • Reactive oxygen species enhance differentiation of human embryonic stem cells into mesendodermal lineage
    • Ji, A.-R. et al. Reactive oxygen species enhance differentiation of human embryonic stem cells into mesendodermal lineage. Exp. Mol. Med. 42, 175-186 (2010).
    • (2010) Exp. Mol. Med. , vol.42 , pp. 175-186
    • Ji, A.-R.1
  • 41
    • 77950630969 scopus 로고    scopus 로고
    • Growth factor erv1-like modulates drp1 to preserve mitochondrial dynamics and function in mouse embryonic stem cells
    • Todd, L. R. et al. Growth factor erv1-like modulates drp1 to preserve mitochondrial dynamics and function in mouse embryonic stem cells. Mol. Biol. Cell 21, 1225-1236 (2010).
    • (2010) Mol. Biol. Cell , vol.21 , pp. 1225-1236
    • Todd, L.R.1
  • 42
    • 11244281579 scopus 로고    scopus 로고
    • Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4
    • Li, Y. et al. Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4. Blood 105, 635-637 (2005).
    • (2005) Blood , vol.105 , pp. 635-637
    • Li, Y.1
  • 43
    • 84862843347 scopus 로고    scopus 로고
    • P53-facilitated miR-199a-3p regulates somatic cell reprogramming
    • Wang, J. et al. p53-facilitated miR-199a-3p regulates somatic cell reprogramming. Stem Cells 30, 1405-1413 (2012).
    • (2012) Stem Cells , vol.30 , pp. 1405-1413
    • Wang, J.1
  • 44
    • 84876569025 scopus 로고    scopus 로고
    • Regulation of L-threonine dehydrogenase in somatic cell reprogramming
    • Han, C. et al. Regulation of L-threonine dehydrogenase in somatic cell reprogramming. Stem Cells 31, 953-965 (2013).
    • (2013) Stem Cells , vol.31 , pp. 953-965
    • Han, C.1
  • 45
    • 34447308810 scopus 로고    scopus 로고
    • Phosphorylation of Pirh2 by Calmodulin-dependent kinase II impairs its ability to ubiquitinate p53
    • Duan, S. et al. Phosphorylation of Pirh2 by Calmodulin-dependent kinase II impairs its ability to ubiquitinate p53. EMBO J. 26, 3062-3074 (2007).
    • (2007) EMBO J. , vol.26 , pp. 3062-3074
    • Duan, S.1
  • 46
    • 33845193134 scopus 로고    scopus 로고
    • The Bad guy cooperates with good cop p53: Bad is transcriptionally up-regulated by p53 and forms a Bad/p53 complex at the mitochondria to induce apoptosis
    • Jiang, P., Du, W., Heese, K. & Wu, M. The Bad guy cooperates with good cop p53: Bad is transcriptionally up-regulated by p53 and forms a Bad/p53 complex at the mitochondria to induce apoptosis. Mol. Cell. Biol. 26, 9071-9082 (2006).
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 9071-9082
    • Jiang, P.1    Du, W.2    Heese, K.3    Wu, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.