Phosphorylation of Pirh2 by Calmodulin-dependent kinase II impairs its ability to ubiquitinate p53

EMBO Journal

Volumn 26, Issue 13, 2007, Pages 3062-3074

  Duan, Shanshan ^a   Yao, Zhan ^a   Hou, Dezhi ^a   Wu, Zhengsheng ^c   Zhu, Wei Guo ^b   Wu, Mian ^a,d  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c ANHUI MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

CaMK II; p53; Phosphorylation; Pirh2; Ubiquitination

Indexed keywords

PROTEIN; PROTEIN KINASE (CALCIUM,CALMODULIN) II; PROTEIN P53; PROTEIN PIRH2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOREGULATION; CANCER GROWTH; CARCINOGENICITY; CELL CYCLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEEDBACK SYSTEM; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; REGULATORY MECHANISM; UBIQUITINATION;

AMINO ACID SEQUENCE; ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELL CYCLE; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CONSERVED SEQUENCE; GENE EXPRESSION REGULATION; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PHOSPHOSERINE; PHOSPHOTHREONINE; PROTEIN BINDING; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 34447308810     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601749     Document Type: Article

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