Multiple cyp51A-based mechanisms identified in azole-resistant isolates of Aspergillus fumigatus from China

Antimicrobial Agents and Chemotherapy

Volumn 59, Issue 7, 2015, Pages 4321-4325

  Liu, Musang ^a   Zeng, Rong ^a   Zhang, Lili ^a   Li, Dongmei ^a,b   Lv, Guixia ^a   Shen, Yongnian ^a   Zheng, Hailin ^a   Zhang, Qiangqiang ^c   Zhao, Jingjun ^d   Zheng, Nan ^e   Liu, Weida ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^c FUDAN UNIVERSITY   (China)

^d TONGJI UNIVERSITY   (China)

^e NANJING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FLUCONAZOLE; ITRACONAZOLE; POSACONAZOLE; TRIAZOLE DERIVATIVE; VORICONAZOLE; ANTIFUNGAL AGENT; CYTOCHROME P-450 CYP51A, ASPERGILLUS; CYTOCHROME P450; FUNGAL PROTEIN; PYRROLE DERIVATIVE;

ANTIFUNGAL RESISTANCE; ARTICLE; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CHINA; CONTROLLED STUDY; CYP51A GENE; FUNGAL GENE; FUNGAL STRAIN; FUNGUS IDENTIFICATION; GENE IDENTIFICATION; GENOTYPE; MINIMUM INHIBITORY CONCENTRATION; MUTATION RATE; MUTATOR GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STRAIN DIFFERENCE; STRAIN IDENTIFICATION; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MOLECULAR GENETICS; MUTATION;

ANTIFUNGAL AGENTS; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; AZOLES; CHINA; CYTOCHROME P-450 ENZYME SYSTEM; DRUG RESISTANCE, FUNGAL; FUNGAL PROTEINS; GENOTYPE; HUMANS; ITRACONAZOLE; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUTATION;

EID: 84931291738     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00003-15     Document Type: Article

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