-
1
-
-
56749159784
-
Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism
-
doi:10.1371/journal.pmed.0050219
-
Snelders E, van der Lee HA, Kuijpers J, Rijs AJ, Varga J, Samson RA, Mellado E, Donders AR, Melchers WJ, Verweij PE. 2008. Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism. PLoS Med. 5:e219. doi:10.1371/journal.pmed.0050219.
-
(2008)
PLoS Med.
, vol.5
-
-
Snelders, E.1
Van Der Lee, H.A.2
Kuijpers, J.3
Rijs, A.J.4
Varga, J.5
Samson, R.A.6
Mellado, E.7
Donders, A.R.8
Melchers, W.J.9
Verweij, P.E.10
-
2
-
-
67650657544
-
Frequency and evolution of azole resistance in Aspergillus fumigatus associated with treatment failure
-
Howard SJ, Cerar D, Anderson MJ, Albarrag A, Fisher MC, Pasqualotto AC, Laverdiere M, Arendrup MC, Perlin DS, Denning DW. 2009. Frequency and evolution of azole resistance in Aspergillus fumigatus associated with treatment failure. Emerg. Infect. Dis. 15:1068-1076.
-
(2009)
Emerg. Infect. Dis.
, vol.15
, pp. 1068-1076
-
-
Howard, S.J.1
Cerar, D.2
Anderson, M.J.3
Albarrag, A.4
Fisher, M.C.5
Pasqualotto, A.C.6
Laverdiere, M.7
Arendrup, M.C.8
Perlin, D.S.9
Denning, D.W.10
-
3
-
-
79953306496
-
Azole resistance in Aspergillus fumigatus: A new challenge in the management of invasive aspergillosis?
-
Snelders E, Melchers WJ, Verweij PE. 2011. Azole resistance in Aspergillus fumigatus: a new challenge in the management of invasive aspergillosis? Future Microbiol. 6:335-347.
-
(2011)
Future Microbiol.
, vol.6
, pp. 335-347
-
-
Snelders, E.1
Melchers, W.J.2
Verweij, P.E.3
-
4
-
-
77957342347
-
Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B
-
Warrilow AG, Melo N, Martel CM, Parker JE, Nes WD, Kelly SL, Kelly DE. 2010. Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B. Antimicrob. Agents Chemother. 54:4225-4234.
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 4225-4234
-
-
Warrilow, A.G.1
Melo, N.2
Martel, C.M.3
Parker, J.E.4
Nes, W.D.5
Kelly, S.L.6
Kelly, D.E.7
-
5
-
-
77952597776
-
Azole resistance profile of amino acid changes in Aspergillus fumigatus CYP51A based on protein homology modeling
-
Snelders E, Karawajczyk A, Schaftenaar G, Verweij PE, Melchers WJ. 2010. Azole resistance profile of amino acid changes in Aspergillus fumigatus CYP51A based on protein homology modeling. Antimicrob. Agents Chemother. 54:2425-2430.
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 2425-2430
-
-
Snelders, E.1
Karawajczyk, A.2
Schaftenaar, G.3
Verweij, P.E.4
Melchers, W.J.5
-
6
-
-
84857757180
-
Triazole fungicides can induce cross-resistance to medical triazoles in Aspergillus fumigatus
-
doi:10.1371/journal.pone.0031801
-
Snelders E, Camps SM, Karawajczyk A, Schaftenaar G, Kema GH, van der Lee HA, Klaassen CH, Melchers WJ, Verweij PE. 2012. Triazole fungicides can induce cross-resistance to medical triazoles in Aspergillus fumigatus. PLoS One 7:e31801. doi:10.1371/journal.pone.0031801.
-
(2012)
PLoS One
, vol.7
-
-
Snelders, E.1
Camps, S.M.2
Karawajczyk, A.3
Schaftenaar, G.4
Kema, G.H.5
Van Der Lee, H.A.6
Klaassen, C.H.7
Melchers, W.J.8
Verweij, P.E.9
-
7
-
-
71549143158
-
Azole resistance in Aspergillus fumigatus: A side-effect of environmental fungicide use?
-
Verweij PE, Snelders E, Kema GH, Mellado E, Melchers WJ. 2009. Azole resistance in Aspergillus fumigatus: a side-effect of environmental fungicide use? Lancet Infect. Dis. 9:789-795.
-
(2009)
Lancet Infect. Dis.
, vol.9
, pp. 789-795
-
-
Verweij, P.E.1
Snelders, E.2
Kema, G.H.3
Mellado, E.4
Melchers, W.J.5
-
8
-
-
84871677613
-
Clonal expansion and emergence of environmental multiple-triazole- resistant Aspergillus fumigatus strains carrying the TR(34)/L98H mutations in the cyp51A gene in India
-
doi:10.1371/journal.pone.0052871
-
Chowdhary A, Kathuria S, Xu J, Sharma C, Sundar G, Singh PK, Gaur SN, Hagen F, Klaassen CH, Meis JF. 2012. Clonal expansion and emergence of environmental multiple-triazole-resistant Aspergillus fumigatus strains carrying the TR(34)/L98H mutations in the cyp51A gene in India. PLoS One 7:e52871. doi:10.1371/journal.pone.0052871.
-
(2012)
PLoS One
, vol.7
-
-
Chowdhary, A.1
Kathuria, S.2
Xu, J.3
Sharma, C.4
Sundar, G.5
Singh, P.K.6
Gaur, S.N.7
Hagen, F.8
Klaassen, C.H.9
Meis, J.F.10
-
9
-
-
78049318458
-
Environmental study of azole-resistant Aspergillus fumigatus and other aspergilli in Austria, Denmark, and Spain
-
Mortensen KL, Mellado E, Lass-Florl C, Rodriguez-Tudela JL, Johansen HK, Arendrup MC. 2010. Environmental study of azole-resistant Aspergillus fumigatus and other aspergilli in Austria, Denmark, and Spain. Antimicrob. Agents Chemother. 54:4545-4549.
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 4545-4549
-
-
Mortensen, K.L.1
Mellado, E.2
Lass-Florl, C.3
Rodriguez-Tudela, J.L.4
Johansen, H.K.5
Arendrup, M.C.6
-
10
-
-
52249111185
-
EUCAST technical note on the method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for conidia-forming moulds
-
Subcommittee on Antifungal Susceptibility Testing of the ESCMID European Committee for Antimicrobial Susceptibility Testing.
-
Subcommittee on Antifungal Susceptibility Testing of the ESCMID European Committee for Antimicrobial Susceptibility Testing. 2008. EUCAST technical note on the method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for conidia-forming moulds. Clin. Microbiol. Infect. 14:982-984.
-
(2008)
Clin. Microbiol. Infect.
, vol.14
, pp. 982-984
-
-
-
11
-
-
84880263067
-
-
posting date. Antifungal agents-breakpoints table for interpretation of MICs.
-
EUCAST. 2013, posting date. Antifungal agents-breakpoints table for interpretation of MICs. http://www.eucast.org/fileadmin/src/media/PDF s/EUCAST-files/Breakpoint-tables/Antifungal-breakpoints-v-5.0.pdf.
-
(2013)
-
-
-
12
-
-
79957438194
-
Aspergillus species and other molds in respiratory samples from patients with cystic fibrosis: A laboratory-based study with focus on Aspergillus fumigatus azole resistance
-
Mortensen KL, Jensen RH, Johansen HK, Skov M, Pressler T, Howard SJ, Leatherbarrow H, Mellado E, Arendrup MC. 2011. Aspergillus species and other molds in respiratory samples from patients with cystic fibrosis: a laboratory-based study with focus on Aspergillus fumigatus azole resistance. J. Clin. Microbiol. 49:2243-2251.
-
(2011)
J. Clin. Microbiol.
, vol.49
, pp. 2243-2251
-
-
Mortensen, K.L.1
Jensen, R.H.2
Johansen, H.K.3
Skov, M.4
Pressler, T.5
Howard, S.J.6
Leatherbarrow, H.7
Mellado, E.8
Arendrup, M.C.9
-
13
-
-
79952646882
-
Probing the role of point mutations in the cyp51A gene from Aspergillus fumigatus in the model yeast Saccharomyces cerevisiae
-
Alcazar-Fuoli L, Mellado E, Cuenca-Estrella M, Sanglard D. 2011. Probing the role of point mutations in the cyp51A gene from Aspergillus fumigatus in the model yeast Saccharomyces cerevisiae. Med. Mycol. 49: 276-284.
-
(2011)
Med. Mycol.
, vol.49
, pp. 276-284
-
-
Alcazar-Fuoli, L.1
Mellado, E.2
Cuenca-Estrella, M.3
Sanglard, D.4
-
14
-
-
84855860621
-
Isolation of multiple-triazole-resistant Aspergillus fumigatus strains carrying the TR/L98H mutations in the cyp51A gene in India
-
Chowdhary A, Kathuria S, Randhawa HS, Gaur SN, Klaassen CH, Meis JF. 2012. Isolation of multiple-triazole-resistant Aspergillus fumigatus strains carrying the TR/L98H mutations in the cyp51A gene in India. J. Antimicrob. Chemother. 67:362-366.
-
(2012)
J. Antimicrob. Chemother.
, vol.67
, pp. 362-366
-
-
Chowdhary, A.1
Kathuria, S.2
Randhawa, H.S.3
Gaur, S.N.4
Klaassen, C.H.5
Meis, J.F.6
-
15
-
-
80051827318
-
Azole resistance in Aspergillus fumigatus isolates from the ARTEMIS global surveillance study is primarily due to the TR/L98H mutation in the cyp51A gene
-
Lockhart SR, Frade JP, Etienne KA, Pfaller MA, Diekema DJ, Balajee SA. 2011. Azole resistance in Aspergillus fumigatus isolates from the ARTEMIS global surveillance study is primarily due to the TR/L98H mutation in the cyp51A gene. Antimicrob. Agents Chemother. 55:4465-4468.
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 4465-4468
-
-
Lockhart, S.R.1
Frade, J.P.2
Etienne, K.A.3
Pfaller, M.A.4
Diekema, D.J.5
Balajee, S.A.6
-
16
-
-
84856074224
-
High prevalence of azole-resistant Aspergillus fumigatus in adults with cystic fibrosis exposed to itraconazole
-
Burgel PR, Baixench MT, Amsellem M, Audureau E, Chapron J, Kanaan R, Honore I, Dupouy-Camet J, Dusser D, Klaassen CH, Meis JF, Hubert D, Paugam A. 2012. High prevalence of azole-resistant Aspergillus fumigatus in adults with cystic fibrosis exposed to itraconazole. Antimicrob. Agents Chemother. 56:869-874.
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 869-874
-
-
Burgel, P.R.1
Baixench, M.T.2
Amsellem, M.3
Audureau, E.4
Chapron, J.5
Kanaan, R.6
Honore, I.7
Dupouy-Camet, J.8
Dusser, D.9
Klaassen, C.H.10
Meis, J.F.11
Hubert, D.12
Paugam, A.13
-
17
-
-
79953869925
-
Highfrequency triazole resistance found in nonculturable Aspergillus fumigatus from lungs of patients with chronic fungal disease
-
Denning DW, Park S, Lass-Florl C, Fraczek MG, Kirwan M, Gore R, Smith J, Bueid A, Moore CB, Bowyer P, Perlin DS. 2011. Highfrequency triazole resistance found in nonculturable Aspergillus fumigatus from lungs of patients with chronic fungal disease. Clin. Infect. Dis. 52: 1123-1129.
-
(2011)
Clin. Infect. Dis.
, vol.52
, pp. 1123-1129
-
-
Denning, D.W.1
Park, S.2
Lass-Florl, C.3
Fraczek, M.G.4
Kirwan, M.5
Gore, R.6
Smith, J.7
Bueid, A.8
Moore, C.B.9
Bowyer, P.10
Perlin, D.S.11
-
18
-
-
84455170146
-
Rapid induction of multiple resistance mechanisms in Aspergillus fumigatus during azole therapy: A case study and review of the literature
-
Camps SM, van der Linden JW, Li Y, Kuijper EJ, van Dissel JT, Verweij PE, Melchers WJ. 2012. Rapid induction of multiple resistance mechanisms in Aspergillus fumigatus during azole therapy: a case study and review of the literature. Antimicrob. Agents Chemother. 56:10-16.
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 10-16
-
-
Camps, S.M.1
Van Der Linden, J.W.2
Li, Y.3
Kuijper, E.J.4
Van Dissel, J.T.5
Verweij, P.E.6
Melchers, W.J.7
-
19
-
-
77956302523
-
Development of azole resistance in Aspergillus fumigatus during azole therapy associated with change in virulence
-
doi:10.1371/journal.pone .0010080
-
Arendrup MC, Mavridou E, Mortensen KL, Snelders E, Frimodt-Moller N, Khan H, Melchers WJ, Verweij PE. 2010. Development of azole resistance in Aspergillus fumigatus during azole therapy associated with change in virulence. PLoS One 5:e10080. doi:10.1371/journal.pone .0010080.
-
(2010)
PLoS One
, vol.5
-
-
Arendrup, M.C.1
Mavridou, E.2
Mortensen, K.L.3
Snelders, E.4
Frimodt-Moller, N.5
Khan, H.6
Melchers, W.J.7
Verweij, P.E.8
-
20
-
-
84870590660
-
Discovery of a hapE mutation that causes azole resistance in Aspergillus fumigatus through whole genome sequencing and sexual crossing
-
doi:10.1371/journal.pone .0050034
-
Camps SM, Dutilh BE, Arendrup MC, Rijs AJ, Snelders E, Huynen MA, Verweij PE, Melchers WJ. 2012. Discovery of a hapE mutation that causes azole resistance in Aspergillus fumigatus through whole genome sequencing and sexual crossing. PLoS One 7:e50034. doi:10.1371/journal.pone .0050034.
-
(2012)
PLoS One
, vol.7
-
-
Camps, S.M.1
Dutilh, B.E.2
Arendrup, M.C.3
Rijs, A.J.4
Snelders, E.5
Huynen, M.A.6
Verweij, P.E.7
Melchers, W.J.8
-
21
-
-
80054697382
-
Interrogation of related clinical pan-azoleresistant Aspergillus fumigatus strains: G138C, Y431C, and G434C single nucleotide polymorphisms in cyp51A, upregulation of cyp51A, and integration and activation of transposon Atf1 in the cyp51A promoter
-
Albarrag AM, Anderson MJ, Howard SJ, Robson GD, Warn PA, Sanglard D, Denning DW. 2011. Interrogation of related clinical pan-azoleresistant Aspergillus fumigatus strains: G138C, Y431C, and G434C single nucleotide polymorphisms in cyp51A, upregulation of cyp51A, and integration and activation of transposon Atf1 in the cyp51A promoter. Antimicrob. Agents Chemother. 55:5113-5121.
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 5113-5121
-
-
Albarrag, A.M.1
Anderson, M.J.2
Howard, S.J.3
Robson, G.D.4
Warn, P.A.5
Sanglard, D.6
Denning, D.W.7
-
22
-
-
0036346165
-
Increased expression of a novel Aspergillus fumigatus ABC transporter gene, atrF, in the presence of itraconazole in an itraconazole resistant clinical isolate
-
Slaven JW, Anderson MJ, Sanglard D, Dixon GK, Bille J, Roberts IS, Denning DW. 2002. Increased expression of a novel Aspergillus fumigatus ABC transporter gene, atrF, in the presence of itraconazole in an itraconazole resistant clinical isolate. Fungal Genet. Biol. 36:199-206.
-
(2002)
Fungal Genet. Biol.
, vol.36
, pp. 199-206
-
-
Slaven, J.W.1
Anderson, M.J.2
Sanglard, D.3
Dixon, G.K.4
Bille, J.5
Roberts, I.S.6
Denning, D.W.7
-
23
-
-
84862241442
-
Identification of novel genes conferring altered azole susceptibility in Aspergillus fumigatus
-
Bowyer P, Mosquera J, Anderson M, Birch M, Bromley M, Denning DW. 2012. Identification of novel genes conferring altered azole susceptibility in Aspergillus fumigatus. FEMS Microbiol. Lett. 332:10-19.
-
(2012)
FEMS Microbiol. Lett.
, vol.332
, pp. 10-19
-
-
Bowyer, P.1
Mosquera, J.2
Anderson, M.3
Birch, M.4
Bromley, M.5
Denning, D.W.6
-
24
-
-
84878623072
-
Invasive aspergillosis: New insights into disease, diagnostic and treatment
-
Karthaus M, Buchheidt D. 2013. Invasive aspergillosis: new insights into disease, diagnostic and treatment. Curr. Pharm. Des. 19:3569-3594.
-
(2013)
Curr. Pharm. Des.
, vol.19
, pp. 3569-3594
-
-
Karthaus, M.1
Buchheidt, D.2
-
25
-
-
0003503732
-
-
2nd ed. American Society for Microbiology, Washington, DC
-
De Hoog G, Guarro J, Figueras M. 2000. Atlas of clinical fungi, 2nd ed. American Society for Microbiology, Washington, D. C.
-
(2000)
Atlas of Clinical Fungi
-
-
De Hoog, G.1
Guarro, J.2
Figueras, M.3
|