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Volumn 43, Issue 10, 2015, Pages 4814-4822

Splice junctions are constrained by protein disorder

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; INTRINSICALLY DISORDERED PROTEIN; NUCLEOTIDE; RNA SPLICING;

EID: 84931275197     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv407     Document Type: Article
Times cited : (14)

References (32)
  • 1
    • 84890058974 scopus 로고    scopus 로고
    • The hidden codes that shape protein evolution
    • Weatheritt, R.J. and Babu, M.M. (2013) The hidden codes that shape protein evolution. Science, 342, 1325-1326.
    • (2013) Science , vol.342 , pp. 1325-1326
    • Weatheritt, R.J.1    Babu, M.M.2
  • 2
    • 70349333474 scopus 로고    scopus 로고
    • Why there is more to protein evolution than protein function: Splicing, nucleosomes and dual-coding sequence
    • Warnecke, T., Weber, C.C. and Hurst, L.D. (2009) Why there is more to protein evolution than protein function: splicing, nucleosomes and dual-coding sequence. Biochem. Soc. Trans., 37, 756-761.
    • (2009) Biochem. Soc. Trans. , vol.37 , pp. 756-761
    • Warnecke, T.1    Weber, C.C.2    Hurst, L.D.3
  • 7
    • 77949916296 scopus 로고    scopus 로고
    • Understanding protein non-folding
    • Uversky, V.N. and Dunker, A.K. (2010) Understanding protein non-folding. Biochim. Biophys. Acta, 1804, 1231-1264.
    • (2010) Biochim. Biophys. Acta , vol.1804 , pp. 1231-1264
    • Uversky, V.N.1    Dunker, A.K.2
  • 9
    • 70350569286 scopus 로고    scopus 로고
    • Mechanisms of alternative splicing regulation: Insights from molecular and genomics approaches
    • Chen, M. and Manley, J.L. (2009) Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches. Nat. Rev. Mol. Cell. Biol., 10, 741-754.
    • (2009) Nat. Rev. Mol. Cell. Biol. , vol.10 , pp. 741-754
    • Chen, M.1    Manley, J.L.2
  • 10
    • 77951120000 scopus 로고    scopus 로고
    • Alternative splicing and evolution: Diversifcation, exon defnition and function
    • Keren, H., Lev-Maor, G. and Ast, G. (2010) Alternative splicing and evolution: diversifcation, exon defnition and function. Nat. Rev. Genet., 11, 345-355.
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 345-355
    • Keren, H.1    Lev-Maor, G.2    Ast, G.3
  • 11
    • 0036207384 scopus 로고    scopus 로고
    • Listening to silence and understanding nonsense: Exonic mutations that affect splicing
    • Cartegni, L., Chew, S.L. and Krainer, A.R. (2002) Listening to silence and understanding nonsense: exonic mutations that affect splicing. Nat. Rev. Genet., 3, 285-298.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 285-298
    • Cartegni, L.1    Chew, S.L.2    Krainer, A.R.3
  • 12
    • 0001468848 scopus 로고    scopus 로고
    • Splicing of Precursors to mRNAs by the Spliceosomes
    • Gesteland, RF, Cech, TR and Atkins, JF (eds) Second Edition. Cold Spring Harbor Laboratory Press, NY
    • Burge, C.S., Tuschl, T. and Sharp, P.A. (1999) Splicing of Precursors to mRNAs by the Spliceosomes. In: Gesteland, RF, Cech, TR and Atkins, JF (eds). The RNA World, Second Edition. Cold Spring Harbor Laboratory Press, NY, pp. 525-560.
    • (1999) The RNA World , pp. 525-560
    • Burge, C.S.1    Tuschl, T.2    Sharp, P.A.3
  • 13
    • 0031921640 scopus 로고    scopus 로고
    • Statistical features of human exons and their fanking regions
    • Zhang, M.Q. (1998) Statistical features of human exons and their fanking regions. Hum. Mol. Genet., 7, 919-932.
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 919-932
    • Zhang, M.Q.1
  • 14
    • 0034161419 scopus 로고    scopus 로고
    • Exonic splicing enhancers: Mechanism of action, diversity and role in human genetic diseases
    • Blencowe, B.J. (2000) Exonic splicing enhancers: Mechanism of action, diversity and role in human genetic diseases. Trends Biochem. Sci., 25, 106-110.
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 106-110
    • Blencowe, B.J.1
  • 15
    • 0037047644 scopus 로고    scopus 로고
    • Predictive identifcation of exonic splicing enhancers in human genes
    • Fairbrother, W.G., Yeh, R.-F., Sharp, P.A. and Burge, C.B. (2002) Predictive identifcation of exonic splicing enhancers in human genes. Science, 297, 1007-1013.
    • (2002) Science , vol.297 , pp. 1007-1013
    • Fairbrother, W.G.1    Yeh, R.-F.2    Sharp, P.A.3    Burge, C.B.4
  • 17
    • 43549084386 scopus 로고    scopus 로고
    • Finding exonic islands in a sea of non-coding sequence: Splicing related constraints on protein composition and evolution are common in intron-rich genomes
    • Warnecke, T., Parmley, J.L. and Hurst, L.D. (2008) Finding exonic islands in a sea of non-coding sequence: splicing related constraints on protein composition and evolution are common in intron-rich genomes. Genome Biol., 9, R29.
    • (2008) Genome Biol. , vol.9 , pp. R29
    • Warnecke, T.1    Parmley, J.L.2    Hurst, L.D.3
  • 18
    • 84931289173 scopus 로고    scopus 로고
    • Why Selection Might Be Stronger When Populations Are Small: Intron Size and Density Predict within and between-Species Usage of Exonic Splice Associated cis-Motifs
    • Wu, X. and Hurst, L.D. (2015) Why Selection Might Be Stronger When Populations Are Small: Intron Size and Density Predict within and between-Species Usage of Exonic Splice Associated cis-Motifs. Mol. Biol. Evol., doi:10.1093/molbev/msv069.
    • (2015) Mol. Biol. Evol
    • Wu, X.1    Hurst, L.D.2
  • 20
    • 84877306983 scopus 로고    scopus 로고
    • Exon-phase symmetry and intrinsic structural disorder promote modular evolution in the human genome
    • Schad, E., Kalmar, L. and Tompa, P. (2013) Exon-phase symmetry and intrinsic structural disorder promote modular evolution in the human genome. Nucleic Acids Res., 41, 4409-4422.
    • (2013) Nucleic Acids Res. , vol.41 , pp. 4409-4422
    • Schad, E.1    Kalmar, L.2    Tompa, P.3
  • 22
    • 84901675912 scopus 로고    scopus 로고
    • Synonymous Constraint ElementsShow a Tendency to Encode Intrinsically Disordered Protein Segments
    • Macossay-Castillo, M., Kosol, S., Tompa, P. and Pancsa, R. (2014) Synonymous Constraint ElementsShow a Tendency to Encode Intrinsically Disordered Protein Segments. PLoS Comput. Biol., 10, e1003607.
    • (2014) PLoS Comput. Biol. , vol.10 , pp. e1003607
    • MacOssay-Castillo, M.1    Kosol, S.2    Tompa, P.3    Pancsa, R.4
  • 24
    • 0035798406 scopus 로고    scopus 로고
    • Assignment of homology to genome sequences using a library of hidden Markov models that represent all proteins of known structure
    • Gough, J., Karplus, K., Hughey, R. and Chothia, C. (2001) Assignment of homology to genome sequences using a library of hidden Markov models that represent all proteins of known structure. J. Mol. Biol., 313, 903-919.
    • (2001) J. Mol. Biol. , vol.313 , pp. 903-919
    • Gough, J.1    Karplus, K.2    Hughey, R.3    Chothia, C.4
  • 25
    • 84890527710 scopus 로고    scopus 로고
    • The evolution, impact and properties of exonic splice enhancers
    • Cáceres, E.F. and Hurst, L.D. (2013) The evolution, impact and properties of exonic splice enhancers. Genome Biol., 14, R143.
    • (2013) Genome Biol. , vol.14 , pp. R143
    • Cáceres, E.F.1    Hurst, L.D.2
  • 26
    • 33746630984 scopus 로고    scopus 로고
    • Wiggle-predicting functionally fexible regions from primary sequence
    • Gu, J., Gribskov, M. and Bourne, P.E. (2006) Wiggle-predicting functionally fexible regions from primary sequence. PLoS Comput. Biol., 2, e90.
    • (2006) PLoS Comput. Biol. , vol.2 , pp. e90
    • Gu, J.1    Gribskov, M.2    Bourne, P.E.3
  • 27
    • 38049061206 scopus 로고    scopus 로고
    • Alternative splicing: Current perspectives
    • Kim, E., Goren, A. and Ast, G. (2008) Alternative splicing: current perspectives. Bioessays, 30, 38-47.
    • (2008) Bioessays , vol.30 , pp. 38-47
    • Kim, E.1    Goren, A.2    Ast, G.3
  • 28
    • 84862992463 scopus 로고    scopus 로고
    • Tissue-specifc splicing of disordered segments that embed binding motifs rewires protein interaction networks
    • Buljan, M., Chalancon, G., Eustermann, S., Wagner, G.P., Fuxreiter, M., Bateman, A. and Babu, M.M. (2012) Tissue-specifc splicing of disordered segments that embed binding motifs rewires protein interaction networks. Mol. Cell, 46, 871-883.
    • (2012) Mol. Cell , vol.46 , pp. 871-883
    • Buljan, M.1    Chalancon, G.2    Eustermann, S.3    Wagner, G.P.4    Fuxreiter, M.5    Bateman, A.6    Babu, M.M.7
  • 29
    • 84925114160 scopus 로고    scopus 로고
    • Intrinsically disordered proteins in cellular signalling and regulation
    • Wright, P.E. and Dyson, H.J. (2015) Intrinsically disordered proteins in cellular signalling and regulation. Nat. Rev. Mol. Cell. Biol., 16, 18-29.
    • (2015) Nat. Rev. Mol. Cell. Biol. , vol.16 , pp. 18-29
    • Wright, P.E.1    Dyson, H.J.2
  • 31
  • 32
    • 33846681383 scopus 로고    scopus 로고
    • Different levels of alternative splicing among eukaryotes
    • Kim, E., Magen, A. and Ast, G. (2007) Different levels of alternative splicing among eukaryotes. Nucleic Acids Res., 35, 125-131.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 125-131
    • Kim, E.1    Magen, A.2    Ast, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.