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Volumn 15, Issue 1, 2015, Pages

Systematic review and mixed treatment comparison of intravitreal aflibercept with other therapies for diabetic macular edema (DME)

Author keywords

Diabetic macular edema (DME); Intravitreal aflibercept; Intravitreal ranibizumab; Meta analysis; Systematic review

Indexed keywords

AFLIBERCEPT; DEXAMETHASONE; GLUCOCORTICOID; HYBRID PROTEIN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR; VEGFA PROTEIN, HUMAN;

EID: 84931272312     PISSN: None     EISSN: 14712415     Source Type: Journal    
DOI: 10.1186/s12886-015-0035-x     Document Type: Article
Times cited : (28)

References (43)
  • 1
    • 54949133248 scopus 로고    scopus 로고
    • The Wisconsin epidemiologic study of diabetic retinopathy: XXII the twenty-five-year progression of retinopathy in persons with type 1 diabetes
    • 2761813 19068374
    • Klein R, Knudtson MD, Lee KE, Gangnon R, Klein BE. The Wisconsin epidemiologic study of diabetic retinopathy: XXII the twenty-five-year progression of retinopathy in persons with type 1 diabetes. Ophthalmology. 2008;115:1859-68.
    • (2008) Ophthalmology , vol.115 , pp. 1859-1868
    • Klein, R.1    Knudtson, M.D.2    Lee, K.E.3    Gangnon, R.4    Klein, B.E.5
  • 2
    • 0022347471 scopus 로고
    • Photocoagulation for diabetic macular edema. Early Treatment Diabetic Retinopathy Study report number 1. Early Treatment Diabetic Retinopathy Study research group
    • Photocoagulation for diabetic macular edema. Early Treatment Diabetic Retinopathy Study report number 1. Early Treatment Diabetic Retinopathy Study research group. Arch Ophthalmol. 1985;103:1796-1806.
    • (1985) Arch Ophthalmol , vol.103 , pp. 1796-1806
  • 3
  • 4
    • 77950901310 scopus 로고    scopus 로고
    • Vascular responses to hypoxia and ischemia
    • 1:CAS:528:DC%2BC3cXktFOmur4%3D 2841694 19729615
    • Semenza GL. Vascular responses to hypoxia and ischemia. Arterioscler Thromb Vasc Biol. 2010;30:648-52.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 648-652
    • Semenza, G.L.1
  • 5
    • 84897830175 scopus 로고    scopus 로고
    • Ocular anti-VEGF therapy for diabetic retinopathy: The role of VEGF in the pathogenesis of diabetic retinopathy
    • 1:CAS:528:DC%2BC2cXosVSlt7w%3D 24652720
    • Simo R, Sundstrom JM, Antonetti DA. Ocular anti-VEGF therapy for diabetic retinopathy: the role of VEGF in the pathogenesis of diabetic retinopathy. Diabetes Care. 2014;37:893-9.
    • (2014) Diabetes Care , vol.37 , pp. 893-899
    • Simo, R.1    Sundstrom, J.M.2    Antonetti, D.A.3
  • 6
    • 84899447918 scopus 로고    scopus 로고
    • Treatment of diabetic macular edema with sustained-release glucocorticoids: Intravitreal triamcinolone acetonide, dexamethasone implant, and fluocinolone acetonide implant
    • 1:CAS:528:DC%2BC2cXntVemsrk%3D 24661081
    • Ciulla TA, Harris A, McIntyre N, Jonescu-Cuypers C. Treatment of diabetic macular edema with sustained-release glucocorticoids: intravitreal triamcinolone acetonide, dexamethasone implant, and fluocinolone acetonide implant. Expert Opin Pharmacother. 2014;15:953-9.
    • (2014) Expert Opin Pharmacother , vol.15 , pp. 953-959
    • Ciulla, T.A.1    Harris, A.2    McIntyre, N.3    Jonescu-Cuypers, C.4
  • 7
    • 84924871458 scopus 로고    scopus 로고
    • Vascular endothelial growth factor trap-eye (Aflibercept) for the management of diabetic macular edema
    • 3874490 24379921
    • Moradi A, Sepah YJ, Sadiq MA, Nasir H, Kherani S, Sophie R, et al. Vascular endothelial growth factor trap-eye (Aflibercept) for the management of diabetic macular edema. World J Diabetes. 2013;4:303-9.
    • (2013) World J Diabetes , vol.4 , pp. 303-309
    • Moradi, A.1    Sepah, Y.J.2    Sadiq, M.A.3    Nasir, H.4    Kherani, S.5    Sophie, R.6
  • 8
    • 43649083100 scopus 로고    scopus 로고
    • Predicted biological activity of intravitreal VEGF trap
    • 1:STN:280:DC%2BD1c3ns1Chtw%3D%3D 18356264
    • Stewart MW, Rosenfeld PJ. Predicted biological activity of intravitreal VEGF trap. Br J Ophthalmol. 2008;92:667-8.
    • (2008) Br J Ophthalmol , vol.92 , pp. 667-668
    • Stewart, M.W.1    Rosenfeld, P.J.2
  • 9
    • 84896968297 scopus 로고    scopus 로고
    • Capacity of aflibercept to counteract VEGF-stimulated abnormal behavior of retinal microvascular endothelial cells
    • 1:CAS:528:DC%2BC2cXnsFCgsro%3D 24631334
    • Deissler HL, Lang GK, Lang GE. Capacity of aflibercept to counteract VEGF-stimulated abnormal behavior of retinal microvascular endothelial cells. Exp Eye Res. 2014;122:20-31.
    • (2014) Exp Eye Res , vol.122 , pp. 20-31
    • Deissler, H.L.1    Lang, G.K.2    Lang, G.E.3
  • 10
    • 84890551871 scopus 로고    scopus 로고
    • Ranibizumab efficiently blocks migration but not proliferation induced by growth factor combinations including VEGF in retinal endothelial cells
    • 1:CAS:528:DC%2BC3sXhsV2jsbvN 3777160 23760670
    • Deissler HL, Deissler H, Lang GK, Lang GE. Ranibizumab efficiently blocks migration but not proliferation induced by growth factor combinations including VEGF in retinal endothelial cells. Graefes Arch Clin Exp Ophthalmol. 2013;251:2345-53.
    • (2013) Graefes Arch Clin Exp Ophthalmol , vol.251 , pp. 2345-2353
    • Deissler, H.L.1    Deissler, H.2    Lang, G.K.3    Lang, G.E.4
  • 11
    • 80052514329 scopus 로고    scopus 로고
    • The da VINCI study: Phase 2 primary results of VEGF Trap-Eye in patients with diabetic macular edema
    • 21546089
    • Do DV, Schmidt-Erfurth U, Gonzalez VH, Gordon CM, Tolentino M, Berliner AJ, et al. The DA VINCI study: phase 2 primary results of VEGF Trap-Eye in patients with diabetic macular edema. Ophthalmology. 2011;118:1819-26.
    • (2011) Ophthalmology , vol.118 , pp. 1819-1826
    • Do, D.V.1    Schmidt-Erfurth, U.2    Gonzalez, V.H.3    Gordon, C.M.4    Tolentino, M.5    Berliner, A.J.6
  • 12
    • 84864444516 scopus 로고    scopus 로고
    • One-year outcomes of the da Vinci study of VEGF Trap-Eye in eyes with diabetic macular edema
    • 22537617
    • Do DV, Nguyen QD, Boyer D, Schmidt-Erfurth U, Brown DM, Vitti R, et al. One-year outcomes of the da Vinci study of VEGF Trap-Eye in eyes with diabetic macular edema. Ophthalmology. 2012;119:1658-65.
    • (2012) Ophthalmology , vol.119 , pp. 1658-1665
    • Do, D.V.1    Nguyen, Q.D.2    Boyer, D.3    Schmidt-Erfurth, U.4    Brown, D.M.5    Vitti, R.6
  • 15
    • 79953311138 scopus 로고    scopus 로고
    • The RESTORE study: Ranibizumab monotherapy or combined with laser versus laser monotherapy for diabetic macular edema
    • 21459215
    • Mitchell P, Bandello F, Schmidt-Erfurth U, Lang GE, Massin P, Schlingemann RO, et al. The RESTORE study: ranibizumab monotherapy or combined with laser versus laser monotherapy for diabetic macular edema. Ophthalmology. 2011;118:615-25.
    • (2011) Ophthalmology , vol.118 , pp. 615-625
    • Mitchell, P.1    Bandello, F.2    Schmidt-Erfurth, U.3    Lang, G.E.4    Massin, P.5    Schlingemann, R.O.6
  • 16
    • 84931289408 scopus 로고    scopus 로고
    • Efficacy and safety of ranibizumab 0.5 mg as monotherapy or adjunctive to laser versus laser monotherapy in Asian patients with visual impairment due to diabetic macular edema: 12-month results of the REVEAL Study
    • Abstract 4664. Presented at
    • Ohji M, Ishibashi T, REVEAL Study Group. Efficacy and safety of ranibizumab 0.5 mg as monotherapy or adjunctive to laser versus laser monotherapy in Asian patients with visual impairment due to diabetic macular edema: 12-month results of the REVEAL Study. Abstract 4664. Presented at: Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), May, 6-9, 2012; Fort Lauderdale, FL.
    • Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), May, 6-9, 2012; Fort Lauderdale, FL
    • Ohji, M.1    Ishibashi, T.2
  • 17
    • 84889571713 scopus 로고    scopus 로고
    • Comparative effectiveness of anti-VEGF agents for diabetic macular edema
    • 24290332
    • Ollendorf DA, Colby JA, Pearson SD. Comparative effectiveness of anti-VEGF agents for diabetic macular edema. Int J Technol Assess Health Care. 2013;29:392-401.
    • (2013) Int J Technol Assess Health Care , vol.29 , pp. 392-401
    • Ollendorf, D.A.1    Colby, J.A.2    Pearson, S.D.3
  • 19
    • 84866598095 scopus 로고    scopus 로고
    • The relative clinical effectiveness of ranibizumab and bevacizumab in diabetic macular oedema: An indirect comparison in a systematic review
    • 3418219 22890029
    • Ford JA, Elders A, Shyangdan D, Royle P, Waugh N. The relative clinical effectiveness of ranibizumab and bevacizumab in diabetic macular oedema: an indirect comparison in a systematic review. BMJ. 2012;345:e5182.
    • (2012) BMJ , vol.345
    • Ford, J.A.1    Elders, A.2    Shyangdan, D.3    Royle, P.4    Waugh, N.5
  • 20
    • 84925423332 scopus 로고    scopus 로고
    • Aflibercept, bevacizumab, or ranibizumab for diabetic macular edema
    • The Diabetic Retinopathy Clinical Research Network. Aflibercept, bevacizumab, or ranibizumab for diabetic macular edema. N Engl J Med. 2015;372:1193-203.
    • (2015) N Engl J Med , vol.372 , pp. 1193-1203
    • The Diabetic Retinopathy Clinical Research Network1
  • 24
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • 12111919
    • Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21:1539-58.
    • (2002) Stat Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 25
    • 67649215130 scopus 로고    scopus 로고
    • Methodological problems in the use of indirect comparisons for evaluating healthcare interventions: Survey of published systematic reviews
    • 2665205 19346285
    • Song F, Loke YK, Walsh T, Glenny AM, Eastwood AJ, Altman DG. Methodological problems in the use of indirect comparisons for evaluating healthcare interventions: survey of published systematic reviews. BMJ. 2009;338:b1147.
    • (2009) BMJ , vol.338
    • Song, F.1    Loke, Y.K.2    Walsh, T.3    Glenny, A.M.4    Eastwood, A.J.5    Altman, D.G.6
  • 26
    • 79959960493 scopus 로고    scopus 로고
    • Conducting indirect-treatment-comparison and network-meta-analysis studies: Report of the ISPOR task force on indirect treatment comparisons good research practices: Part 2
    • 21669367
    • Hoaglin DC, Hawkins N, Jansen JP, Scott DA, Itzler R, Cappelleri JC, et al. Conducting indirect-treatment-comparison and network-meta-analysis studies: report of the ISPOR task force on indirect treatment comparisons good research practices: part 2. Value Health. 2011;14:429-37.
    • (2011) Value Health , vol.14 , pp. 429-437
    • Hoaglin, D.C.1    Hawkins, N.2    Jansen, J.P.3    Scott, D.A.4    Itzler, R.5    Cappelleri, J.C.6
  • 27
    • 0030793120 scopus 로고    scopus 로고
    • The results of direct and indirect treatment comparisons in meta-analysis of randomized controlled trials
    • 1:STN:280:DyaK2szptlygsw%3D%3D 9250266
    • Bucher HC, Guyatt GH, Griffith LE, Walter SD. The results of direct and indirect treatment comparisons in meta-analysis of randomized controlled trials. J Clin Epidemiol. 1997;50:683-91.
    • (1997) J Clin Epidemiol , vol.50 , pp. 683-691
    • Bucher, H.C.1    Guyatt, G.H.2    Griffith, L.E.3    Walter, S.D.4
  • 28
    • 33745663057 scopus 로고    scopus 로고
    • Assessing evidence inconsistency in mixed treatment comparisons
    • Lu G, Ades AE. Assessing evidence inconsistency in mixed treatment comparisons. J Am Stat Assoc. 2014;101:447-59.
    • (2014) J Am Stat Assoc , vol.101 , pp. 447-459
    • Lu, G.1    Ades, A.E.2
  • 32
    • 77952779304 scopus 로고    scopus 로고
    • Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema
    • 2937272 20427088
    • Elman MJ, Aiello LP, Beck RW, Bressler NM, Bressler SB, Edwards AR, et al. Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology. 2010;117:1064-77.
    • (2010) Ophthalmology , vol.117 , pp. 1064-1077
    • Elman, M.J.1    Aiello, L.P.2    Beck, R.W.3    Bressler, N.M.4    Bressler, S.B.5    Edwards, A.R.6
  • 33
    • 79958268827 scopus 로고    scopus 로고
    • Randomized trial evaluating short-term effects of intravitreal ranibizumab or triamcinolone acetonide on macular edema after focal/grid laser for diabetic macular edema in eyes also receiving panretinal photocoagulation
    • 1:CAS:528:DC%2BC38Xjt1ahurk%3D 21394052
    • Googe J, Brucker AJ, Bressler NM, Qin H, Aiello LP, Antoszyk A, et al. Randomized trial evaluating short-term effects of intravitreal ranibizumab or triamcinolone acetonide on macular edema after focal/grid laser for diabetic macular edema in eyes also receiving panretinal photocoagulation. Retina. 2011;31:1009-27.
    • (2011) Retina , vol.31 , pp. 1009-1027
    • Googe, J.1    Brucker, A.J.2    Bressler, N.M.3    Qin, H.4    Aiello, L.P.5    Antoszyk, A.6
  • 35
    • 58249105907 scopus 로고    scopus 로고
    • Combined laser and intravitreal triamcinolone for proliferative diabetic retinopathy and macular edema: One-year results of a randomized clinical trial
    • 1:CAS:528:DC%2BD1MXhtVeisr0%3D 18929352
    • Maia OO Jr, Takahashi BS, Costa RA, Scott IU, Takahashi WY. Combined laser and intravitreal triamcinolone for proliferative diabetic retinopathy and macular edema: one-year results of a randomized clinical trial. Am J Ophthalmol. 2009;147:291-7.
    • (2009) Am J Ophthalmol , vol.147 , pp. 291-297
    • Maia, O.O.1    Takahashi, B.S.2    Costa, R.A.3    Scott, I.U.4    Takahashi, W.Y.5
  • 36
    • 84883775340 scopus 로고    scopus 로고
    • Dexamethasone intravitreal implant in combination with laser photocoagulation for the treatment of diffuse diabetic macular edema
    • 23706947
    • Callanan DG, Gupta S, Boyer DS, Ciulla TA, Singer MA, Kuppermann BD, et al. Dexamethasone intravitreal implant in combination with laser photocoagulation for the treatment of diffuse diabetic macular edema. Ophthalmology. 2013;120:1843-51.
    • (2013) Ophthalmology , vol.120 , pp. 1843-1851
    • Callanan, D.G.1    Gupta, S.2    Boyer, D.S.3    Ciulla, T.A.4    Singer, M.A.5    Kuppermann, B.D.6
  • 37
    • 84885022258 scopus 로고    scopus 로고
    • Long-term outcomes of ranibizumab therapy for diabetic macular edema: The 36-month results from two phase III trials: RISE and RIDE
    • 23706949
    • Brown DM, Nguyen QD, Marcus DM, Boyer DS, Patel S, Feiner L, et al. Long-term outcomes of ranibizumab therapy for diabetic macular edema: the 36-month results from two phase III trials: RISE and RIDE. Ophthalmology. 2013;120:2013-22.
    • (2013) Ophthalmology , vol.120 , pp. 2013-2022
    • Brown, D.M.1    Nguyen, Q.D.2    Marcus, D.M.3    Boyer, D.S.4    Patel, S.5    Feiner, L.6
  • 38
    • 84879772042 scopus 로고    scopus 로고
    • Evidence synthesis for decision making 3: Heterogeneity-subgroups, meta-regression, bias, and bias-adjustment
    • 3704206 23804507
    • Dias S, Sutton AJ, Welton NJ, Ades AE. Evidence synthesis for decision making 3: heterogeneity-subgroups, meta-regression, bias, and bias-adjustment. Med Decis Making. 2013;33:618-40.
    • (2013) Med Decis Making , vol.33 , pp. 618-640
    • Dias, S.1    Sutton, A.J.2    Welton, N.J.3    Ades, A.E.4
  • 39
    • 84904353200 scopus 로고    scopus 로고
    • Efficacy of anti-VEGF and laser photocoagulation in the treatment of visual impairment due to diabetic macular edema: A systematic review and network meta-analysis
    • 4100770 25029255
    • Regnier S, Malcolm W, Allen F, Wright J, Bezlyak V. Efficacy of anti-VEGF and laser photocoagulation in the treatment of visual impairment due to diabetic macular edema: a systematic review and network meta-analysis. PLoS One. 2014;9:e102309.
    • (2014) PLoS One , vol.9
    • Regnier, S.1    Malcolm, W.2    Allen, F.3    Wright, J.4    Bezlyak, V.5
  • 40
    • 84877683463 scopus 로고    scopus 로고
    • Current treatments in diabetic macular oedema: Systematic review and meta-analysis
    • Ford JA, Lois N, Royle P, Clar C, Shyangdan D, Waugh N. Current treatments in diabetic macular oedema: systematic review and meta-analysis. BMJ Open. 2013;3. doi: 10.1136/bmjopen-2012-002269.
    • (2013) BMJ Open , pp. 3
    • Ford, J.A.1    Lois, N.2    Royle, P.3    Clar, C.4    Shyangdan, D.5    Waugh, N.6
  • 41
    • 0035845305 scopus 로고    scopus 로고
    • A new system for grading recommendations in evidence based guidelines
    • 1:STN:280:DC%2BD3Mvlt1Wqtg%3D%3D 1120936 11498496
    • Harbour R, Miller J. A new system for grading recommendations in evidence based guidelines. BMJ. 2001;323:334-6.
    • (2001) BMJ , vol.323 , pp. 334-336
    • Harbour, R.1    Miller, J.2
  • 42
    • 84908469619 scopus 로고    scopus 로고
    • Systemic vascular safety of ranibizumab for age-related macular degeneration: Systematic review and meta-analysis of randomized trials.
    • 25023760
    • Ueta T, Noda Y, Toyama T, Yamaguchi T, Amano S. Systemic vascular safety of ranibizumab for age-related macular degeneration: systematic review and meta-analysis of randomized trials. Ophthalmology. 2014;121:2193-203.
    • (2014) Ophthalmology , vol.121 , pp. 2193-2203
    • Ueta, T.1    Noda, Y.2    Toyama, T.3    Yamaguchi, T.4    Amano, S.5
  • 43
    • 84910053743 scopus 로고    scopus 로고
    • Cardiovascular events and bleeding risk associated with intravitreal antivascular endothelial growth factor monoclonal antibodies: Systematic review and meta-analysis
    • 25058694
    • Thulliez M, Angoulvant D, Le Lez ML, Jonville-Bera AP, Pisella PJ, Gueyffier F, et al. Cardiovascular events and bleeding risk associated with intravitreal antivascular endothelial growth factor monoclonal antibodies: systematic review and meta-analysis. JAMA Ophthalmol. 2014;132:1317-26.
    • (2014) JAMA Ophthalmol , vol.132 , pp. 1317-1326
    • Thulliez, M.1    Angoulvant, D.2    Le Lez, M.L.3    Jonville-Bera, A.P.4    Pisella, P.J.5    Gueyffier, F.6


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