Intravitreal aflibercept for diabetic macular edema

Ophthalmology

Volumn 121, Issue 11, 2014, Pages 2247-2254

  Korobelnik, Jean François ^a,b,c   Do, Diana V ^d   Schmidt Erfurth, Ursula ^e   Boyer, David S ^f   Holz, Frank G ^g   Heier, Jeffrey S ^h   Midena, Edoardo ⁱ   Kaiser, Peter K ^j   Terasaki, Hiroko ^k   Marcus, Dennis M ^l   Nguyen, Quan D ^d   Jaffe, Glenn J ^m   Slakter, Jason S ⁿ   Simader, Christian ^e   Soo, Yuhwen ^o   Schmelter, Thomas ^p   Yancopoulos, George D ^o   Stahl, Neil ^o   Vitti, Robert ^o   Berliner, Alyson J ^o   Zeitz, Oliver ^p,q   Metzig, Carola ^p   Brown, David M ^r   more..

^a HÔPITAL PELLEGRIN   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

^c INSERM   (France)

^d UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^e MEDICAL UNIVERSITY OF VIENNA   (Austria)

^f RETINA VITREOUS ASSOCIATES MEDICAL GROUP   (United States)

^g UNIVERSITY OF BONN   (Germany)

^h TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ UNIVERSITY OF PADOVA   (Italy)

^j LERNER RESEARCH INSTITUTE   (United States)

^k NAGOYA UNIVERSITY HOSPITAL   (Japan)

^l Southeast Retina Center   (United States)

^m DUKE UNIVERSITY EYE CENTER   (United States)

ⁿ VITREOUS RETINA MACULA CONSULTANTS OF NEW YORK   (United States)

^o REGENERON PHARMACEUTICALS INC   (United States)

^p BAYER PHARMA AG   (Germany)

^q UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^r RETINA CONSULTANTS OF HOUSTON   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AFLIBERCEPT; ANGIOGENESIS INHIBITOR; HYBRID PROTEIN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR; VEGFA PROTEIN, HUMAN;

ACUTE HEART INFARCTION; ADULT; ANEMIA; ARTERIAL THROMBOEMBOLISM; ARTICLE; BEST CORRECTED VISUAL ACUITY; CATARACT; CENTRAL RETINAL THICKNESS; CEREBROVASCULAR ACCIDENT; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; DIABETIC MACULAR EDEMA; DIABETIC RETINOPATHY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; FEMALE; HEART INFARCTION; HUMAN; INJECTION SITE INJURY; INJECTION SITE REACTION; INSULIN DEPENDENT DIABETES MELLITUS; INTRAOCULAR PRESSURE ABNORMALITY; LASER COAGULATION; MACULAR DEGENERATION; MAJOR CLINICAL STUDY; MALE; NATIONAL EYE INSTITUTE VISUAL FUNCTION QUESTIONNAIRE; NON INSULIN DEPENDENT DIABETES MELLITUS; OPTICAL COHERENCE TOMOGRAPHY; OSTEOARTHRITIS; OUTCOME ASSESSMENT; PHASE 3 CLINICAL TRIAL; POSTOPERATIVE COMPLICATION; PUNCTATE KERATITIS; RANDOMIZED CONTROLLED TRIAL; RETINA ARTERY OCCLUSION; RETINA DETACHMENT; RETINA EXUDATE; RETINA HEMORRHAGE; RETINA NEOVASCULARIZATION; VISUAL ACUITY; VITREOUS HEMORRHAGE; AGED; ANTAGONISTS AND INHIBITORS; CLINICAL TRIAL; COMPARATIVE STUDY; COMPLICATION; INTRAVITREAL DRUG ADMINISTRATION; MACULAR EDEMA; MIDDLE AGED; MULTICENTER STUDY; PATHOPHYSIOLOGY; PHYSIOLOGY;

AGED; ANGIOGENESIS INHIBITORS; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INTRAVITREAL INJECTIONS; LASER COAGULATION; MACULAR EDEMA; MALE; MIDDLE AGED; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; TOMOGRAPHY, OPTICAL COHERENCE; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VISUAL ACUITY;

EID: 84908897529     PISSN: 01616420     EISSN: 15494713     Source Type: Journal    
DOI: 10.1016/j.ophtha.2014.05.006     Document Type: Article

References (13)

1. D.A. Antonetti, R. Klein, and T.W. Gardner Diabetic retinopathy N Engl J Med 366 2012 1227 1239
2. B. Wirostko, T.Y. Wong, and R. Simo Vascular endothelial growth factor and diabetic complications Prog Retin Eye Res 27 2008 608 621
3. A.W. Stitt, and T.M. Curtis Advanced glycation and retinal pathology during diabetes Pharmacol Rep 57 suppl 2005 156 168
4. Centers for Disease Control and Prevention. National Diabetes Fact Sheet: national estimates and general information on diabetes and prediabetes in the United States. 2011. Available at: www.www.cdc.gov/diabetes/pubs/pdf/ndfs-2011.pdf. Accessed May 10, 2014.
5. Early Treatment Diabetic Retinopathy Study Research Group. Photocoagulation for diabetic macular edema. Early Treatment Diabetic Retinopathy Study report number 1 Arch Ophthalmol 103 1985 1796 1806
6. Diabetic Retinopathy Clinical Research Network M.J. Elman, L.P. Aiello, and R.W. Beck Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema Ophthalmology 117 2010 1064 1077
7. Q.D. Nguyen, D.M. Brown, D.M. Marcus RISE and RIDE Research Group Ranibizumab for diabetic macular edema: results from 2 phase III randomized trials: RISE and RIDE Ophthalmology 119 2012 789 801
8. N. Papadopoulos, J. Martin, and Q. Ruan Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab Angiogenesis 15 2012 171 185
9. J.S. Heier, D.M. Brown, V. Chong VIEW 1 and VIEW 2 Study Groups Intravitreal aflibercept (VEGF Trap-Eye) in wet age-related macular degeneration Ophthalmology 119 2012 2537 2548
10. Early Treatment Diabetic Retinopathy Study Research Group. Fundus photographic risk factors for progression of diabetic retinopathy: ETDRS report number 12 Ophthalmology 98 suppl 1991 823 833
11. P. Mitchell, F. Bandello, U. Schmidt-Erfurth RESTORE Study Group The RESTORE study: ranibizumab monotherapy or combined with laser versus laser monotherapy for diabetic macular edema Ophthalmology 118 2011 615 625
12. Q.D. Nguyen, S.M. Shah, J.S. Heier READ-2 Study Group Primary end point (six months) results of the Ranibizumab for Edema of the mAcula in Diabetes (READ-2) study Ophthalmology 116 2009 2175 2181
13. O. May, H. Arildsen, E.M. Damsgaard, and H. Mickley Prevalence and prediction of silent ischaemia in diabetes mellitus: a population-based study Cardiovasc Res 34 1997 241 247