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Volumn 9, Issue 7, 2014, Pages

EFficacy of anti-VEGF and laser photocoagulation in the treatment of visual impairment due to diabetic macular edema: A systematic review and network meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

AFLIBERCEPT; RANIBIZUMAB; HYBRID PROTEIN; MONOCLONAL ANTIBODY; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR;

EID: 84904353200     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102309     Document Type: Article
Times cited : (57)

References (73)
  • 1
    • 77958566857 scopus 로고    scopus 로고
    • Current approaches to the management of diabetic retinopathy and diabetic macular oedema
    • Boscia F (2010) Current approaches to the management of diabetic retinopathy and diabetic macular oedema. Drugs 70: 2171-2200.
    • (2010) Drugs , vol.70 , pp. 2171-2200
    • Boscia, F.1
  • 3
    • 0041358796 scopus 로고    scopus 로고
    • Diabetic retinopathy and diabetic macular edema: Pathophysiology, screening, and novel therapies
    • DOI 10.2337/diacare.26.9.2653
    • Ciulla TA, Amador AG, Zinman B (2003) Diabetic retinopathy and diabetic macular edema: pathophysiology, screening, and novel therapies. Diabetes Care 26: 2653-2664. (Pubitemid 37055447)
    • (2003) Diabetes Care , vol.26 , Issue.9 , pp. 2653-2664
    • Ciulla, T.A.1    Amador, A.G.2    Zinman, B.3
  • 6
    • 58149347333 scopus 로고    scopus 로고
    • The longitudinal link between visual acuity and health-related quality of life in patients with diabetic retinopathy
    • Matza LS, Rousculp MD, Malley K, Boye KS, Oglesby A (2008) The longitudinal link between visual acuity and health-related quality of life in patients with diabetic retinopathy. Health Qual Life Outcomes 6: 95.
    • (2008) Health Qual Life Outcomes , vol.6 , pp. 95
    • Matza, L.S.1    Rousculp, M.D.2    Malley, K.3    Boye, K.S.4    Oglesby, A.5
  • 8
    • 73749083481 scopus 로고    scopus 로고
    • Global estimates of the prevalence of diabetes for 2010 and 2030
    • Shaw JE, Sicree RA, Zimmet PZ (2010) Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 87: 4-14.
    • (2010) Diabetes Res Clin Pract , vol.87 , pp. 4-14
    • Shaw, J.E.1    Sicree, R.A.2    Zimmet, P.Z.3
  • 9
    • 84899695633 scopus 로고    scopus 로고
    • December Available: Accessed 17 January 2013
    • The Royal College of Ophthalmologists. Diabetic Retinopathy Guidelines, December 2012. Available: http://www.rcophth.ac.uk/page.asp?section= 451§ionTitle= Clinical+Guidelines Accessed 17 January 2013.
    • (2012) Diabetic Retinopathy Guidelines
  • 10
    • 53049095744 scopus 로고    scopus 로고
    • American Academy of Ophthalmology Retina Panel San Francisco, CA: American Academy of Ophthalmology
    • American Academy of Ophthalmology Retina Panel (2008) Preferred Practice Pattern Guidelines. Diabetic Retinopathy. San Francisco, CA: American Academy of Ophthalmology.
    • (2008) Preferred Practice Pattern Guidelines. Diabetic Retinopathy
  • 11
    • 62449171859 scopus 로고    scopus 로고
    • Three-year follow-up of a randomized trial comparing focal/grid photocoagulation and intravitreal triamcinolone for diabetic macular edema
    • Beck RW, Edwards AR, Aiello LP, Bressler NM, Ferris F, et al. (2009) Three-year follow-up of a randomized trial comparing focal/grid photocoagulation and intravitreal triamcinolone for diabetic macular edema. Arch Ophthalmol 127: 245-251.
    • (2009) Arch Ophthalmol , vol.127 , pp. 245-251
    • Beck, R.W.1    Edwards, A.R.2    Aiello, L.P.3    Bressler, N.M.4    Ferris, F.5
  • 12
    • 0022347471 scopus 로고
    • Photocoagulation for diabetic macular edema
    • Early Treatment Diabetic Retinopathy Study Research Group ETDRS Report number 1
    • Early Treatment Diabetic Retinopathy Study Research Group (1985) Photocoagulation for diabetic macular edema. ETDRS Report number 1. Arch Ophthalmol 103: 1796-1806.
    • (1985) Arch Ophthalmol , vol.103 , pp. 1796-1806
  • 13
    • 0023202345 scopus 로고
    • Treatment techniques and clinical guidelines for photocoagulation of diabetic macular edema
    • Early Treatment Diabetic Retinopathy Study Research Group Early Treatment Diabetic Retinopathy Study Report Number 2
    • Early Treatment Diabetic Retinopathy Study Research Group (1987) Treatment techniques and clinical guidelines for photocoagulation of diabetic macular edema. Early Treatment Diabetic Retinopathy Study Report Number 2. Ophthalmology 94: 761-774.
    • (1987) Ophthalmology , vol.94 , pp. 761-774
  • 14
    • 0025892104 scopus 로고
    • Early photocoagulation for diabetic retinopathy
    • Early Treatment Diabetic Retinopathy Study Research Group ETDRS report number 9
    • Early Treatment Diabetic Retinopathy Study Research Group (1991) Early photocoagulation for diabetic retinopathy. ETDRS report number 9. Ophthalmology 98: 766-785.
    • (1991) Ophthalmology , vol.98 , pp. 766-785
  • 15
    • 84859782745 scopus 로고    scopus 로고
    • New approaches for the treatment of diabetic macular oedema: Recommendations by an expert panel
    • Bandello F, Cunha-Vaz J, Chong NV, Lang GE, Massin P, et al. (2012) New approaches for the treatment of diabetic macular oedema: recommendations by an expert panel. Eye 26(4):: 485-493.
    • (2012) Eye , vol.26 , Issue.4 , pp. 485-493
    • Bandello, F.1    Cunha-Vaz, J.2    Chong, N.V.3    Lang, G.E.4    Massin, P.5
  • 16
    • 84904284455 scopus 로고    scopus 로고
    • Updated Available: Accessed 19 Sept 2012
    • Lucentis (ranibizumab) Prescribing information. Updated 2012. Available: http://www.gene.com/gene/products/information/pdf/lucentis-prescribing.pdf Accessed 19 Sept 2012.
    • (2012) Lucentis (Ranibizumab) Prescribing Information
  • 19
    • 79958012399 scopus 로고    scopus 로고
    • A phase 2/3, multicenter, randomized, double-masked, 2-year trial of pegaptanib sodium for the treatment of diabetic macular edema
    • Sultan MB, Zhou D, Loftus J, Dombi T, Ice KS (2011) A phase 2/3, multicenter, randomized, double-masked, 2-year trial of pegaptanib sodium for the treatment of diabetic macular edema. Ophthalmology 118: 1107-1118.
    • (2011) Ophthalmology , vol.118 , pp. 1107-1118
    • Sultan, M.B.1    Zhou, D.2    Loftus, J.3    Dombi, T.4    Ice, K.S.5
  • 20
    • 84856386357 scopus 로고    scopus 로고
    • Changes in vision- and health-related quality of life in patients with diabetic macular edema treated with pegaptanib sodium or sham
    • Loftus JV, Sultan MB, Pleil AM (2011) Changes in vision- and health-related quality of life in patients with diabetic macular edema treated with pegaptanib sodium or sham. Invest Ophthalmol Vis Sci 52: 7498-7505.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 7498-7505
    • Loftus, J.V.1    Sultan, M.B.2    Pleil, A.M.3
  • 21
    • 25844513658 scopus 로고    scopus 로고
    • A phase II randomized double-masked trial of pegaptanib, an antivascular endothelial growth factor aptamer, for diabetic macular edema
    • Cunningham ET, Jr., Adamis AP, Altaweel M, Aiello LP, Bressler NM, et al. (2005) A phase II randomized double-masked trial of pegaptanib, an antivascular endothelial growth factor aptamer, for diabetic macular edema. Ophthalmology 112: 1747-1757.
    • (2005) Ophthalmology , vol.112 , pp. 1747-1757
    • Cunningham Jr., E.T.1    Adamis, A.P.2    Altaweel, M.3    Aiello, L.P.4    Bressler, N.M.5
  • 22
    • 84904336800 scopus 로고    scopus 로고
    • Page last updated: 11 December Available at
    • National Institute for Health and Care Excellence. Macular oedema (diabetic) - pegaptanib sodium [ID452]. Page last updated: 11 December 2013. Available at: http://guidance.nice.org.uk/TAG/280.
    • (2013) Macular Oedema (Diabetic) - Pegaptanib Sodium [ID452]
  • 24
    • 84904278978 scopus 로고    scopus 로고
    • Available at: Accessed 12 February 2014
    • Adcortyl SmPC. Available at: https://www.medicines.org.uk/emc/medicine/ 6392/SPC/Adcortyl+Intra-Articular+Intradermal+Injection+10mg+ml/. Accessed 12 February 2014.
    • Adcortyl SmPC
  • 26
    • 84904322030 scopus 로고    scopus 로고
    • Available: Accessed 07 January 2013
    • ILUVIEN SPC. Available: http://www.mhra.gov.uk/Safetyinformation/ Medicinesinformation/SPCandPILs/?subsName=FLUOCINOLONE%20ACETONIDE&pageID= SecondLevel Accessed 07 January 2013.=
    • ILUVIEN SPC
  • 28
    • 84885350201 scopus 로고    scopus 로고
    • The evolving treatment options for diabetic macular edema
    • Jain A, Varshney N, Smith C (2013) The evolving treatment options for diabetic macular edema. Int J Inflam 2013: e689276.
    • (2013) Int J Inflam , vol.2013
    • Jain, A.1    Varshney, N.2    Smith, C.3
  • 29
    • 84866598095 scopus 로고    scopus 로고
    • The relative clinical effectiveness of ranibizumab and bevacizumab in diabetic macular oedema: An indirect comparison in a systematic review
    • Ford JA, Elders A, Shyangdan D, Royle P, Waugh N (2012) The relative clinical effectiveness of ranibizumab and bevacizumab in diabetic macular oedema: an indirect comparison in a systematic review. BMJ 345: e5182.
    • (2012) BMJ , vol.345
    • Ford, J.A.1    Elders, A.2    Shyangdan, D.3    Royle, P.4    Waugh, N.5
  • 30
    • 84877683463 scopus 로고    scopus 로고
    • Current treatments in diabetic macular oedema: Systematic review and meta-analysis
    • Ford JA, Lois N, Royle P, Clar C, Shyangdan D, et al. (2013) Current treatments in diabetic macular oedema: systematic review and meta-analysis. BMJ open 3: e002269.
    • (2013) BMJ Open , vol.3
    • Ford, J.A.1    Lois, N.2    Royle, P.3    Clar, C.4    Shyangdan, D.5
  • 31
    • 82155197239 scopus 로고    scopus 로고
    • Systematic review of intravitreal bevacizumab injection for treatment of primary diabetic macular oedema
    • Yilmaz T, Cordero-Coma M, Gallagher MJ, Teasley LA (2011) Systematic review of intravitreal bevacizumab injection for treatment of primary diabetic macular oedema. Acta ophthalmologica 89: 709-717.
    • (2011) Acta Ophthalmologica , vol.89 , pp. 709-717
    • Yilmaz, T.1    Cordero-Coma, M.2    Gallagher, M.J.3    Teasley, L.A.4
  • 32
    • 84856055811 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibitors (anti-VEGF) in the management of diabetic macular oedema: A systematic review
    • Zechmeister-Koss I, Huic M (2012) Vascular endothelial growth factor inhibitors (anti-VEGF) in the management of diabetic macular oedema: a systematic review. Br J Ophthalmol 96: 167-178.
    • (2012) Br J Ophthalmol , vol.96 , pp. 167-178
    • Zechmeister-Koss, I.1    Huic, M.2
  • 33
    • 84889571713 scopus 로고    scopus 로고
    • Comparative effectiveness of anti-VEGF agents for diabetic macular edema
    • Ollendorf DA, Colby JA, Pearson SD (2013) Comparative effectiveness of anti-VEGF agents for diabetic macular edema. Int J Technol Asses 29: 392-401.
    • (2013) Int J Technol Asses , vol.29 , pp. 392-401
    • Ollendorf, D.A.1    Colby, J.A.2    Pearson, S.D.3
  • 34
    • 84857260889 scopus 로고    scopus 로고
    • Ranibizumab: In diabetic macular oedema
    • Frampton JE (2012) Ranibizumab: in diabetic macular oedema. Drugs 72: 509-523.
    • (2012) Drugs , vol.72 , pp. 509-523
    • Frampton, J.E.1
  • 35
    • 84863671492 scopus 로고    scopus 로고
    • Intravitreal ranibizumab (Lucentis) for the treatment of diabetic macular edema: A systematic review and meta-analysis of randomized clinical control trials
    • Wang H, Sun X, Liu K, Xu X (2012) Intravitreal ranibizumab (Lucentis) for the treatment of diabetic macular edema: a systematic review and meta-analysis of randomized clinical control trials. Curr Eye Res 37: 661-670.
    • (2012) Curr Eye Res , vol.37 , pp. 661-670
    • Wang, H.1    Sun, X.2    Liu, K.3    Xu, X.4
  • 36
    • 84874181671 scopus 로고    scopus 로고
    • Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for diabetic macular oedema
    • Virgili G, Parravano M, Menchini F, Brunetti M (2012) Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for diabetic macular oedema. Cochrane Database Syst Rev 12: CD007419.
    • (2012) Cochrane Database Syst Rev , vol.12
    • Virgili, G.1    Parravano, M.2    Menchini, F.3    Brunetti, M.4
  • 37
    • 26944454062 scopus 로고    scopus 로고
    • Simultaneous comparison of multiple treatments: Combining direct and indirect evidence
    • Caldwell DM, Ades AE, Higgins JP (2005) Simultaneous comparison of multiple treatments: combining direct and indirect evidence. BMJ 331: 897-900. (Pubitemid 41502718)
    • (2005) British Medical Journal , vol.331 , Issue.7521 , pp. 897-900
    • Caldwell, D.M.1    Ades, A.E.2    Higgins, J.P.T.3
  • 38
    • 84879818084 scopus 로고    scopus 로고
    • Is network meta-analysis as valid as standard pairwise meta-analysis? It all depends on the distribution of effect modifiers
    • Jansen JP, Naci H (2013) Is network meta-analysis as valid as standard pairwise meta-analysis? It all depends on the distribution of effect modifiers. BMC Med 11: 159.
    • (2013) BMC Med , vol.11 , pp. 159
    • Jansen, J.P.1    Naci, H.2
  • 39
    • 53749095958 scopus 로고    scopus 로고
    • Impact of general health status on validity of visual impairment measurement
    • Ahmadian L, Massof R (2008) Impact of general health status on validity of visual impairment measurement. Ophthalmic Epidemiol 15: 345-355.
    • (2008) Ophthalmic Epidemiol , vol.15 , pp. 345-355
    • Ahmadian, L.1    Massof, R.2
  • 40
    • 58449085584 scopus 로고    scopus 로고
    • Improved vision-related function after ranibizumab vs photodynamic therapy: A randomized clinical trial
    • Bressler NM, Chang TS, Fine JT, Dolan CM, Ward J (2009) Improved vision-related function after ranibizumab vs photodynamic therapy: a randomized clinical trial. Arch Ophthalmol 127: 13-21.
    • (2009) Arch Ophthalmol , vol.127 , pp. 13-21
    • Bressler, N.M.1    Chang, T.S.2    Fine, J.T.3    Dolan, C.M.4    Ward, J.5
  • 41
    • 40649108602 scopus 로고    scopus 로고
    • Report from the NEI/FDA Ophthalmic Clinical Trial Design and Endpoints Symposium
    • Csaky KG, Richman EA, Ferris FL, 3rd (2008) Report from the NEI/FDA Ophthalmic Clinical Trial Design and Endpoints Symposium. Invest Ophthalmol Vis Sci 49: 479-489.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 479-489
    • Csaky, K.G.1    Richman, E.A.2    Ferris III, F.L.3
  • 43
    • 0036399209 scopus 로고    scopus 로고
    • Vision-specific instruments for the assessment of health-related quality of life and visual functioning: A literature review
    • Margolis MK, Coyne K, Kennedy-Martin T, Baker T, Schein O, et al. (2002) Vision-specific instruments for the assessment of health-related quality of life and visual functioning: a literature review. Pharmacoeconomics 20: 791-812. (Pubitemid 35216491)
    • (2002) PharmacoEconomics , vol.20 , Issue.12 , pp. 791-812
    • Margolis, M.K.1    Coyne, K.2    Kennedy-Martin, T.3    Baker, T.4    Schein, O.5    Revicki, D.A.6
  • 44
    • 84904284092 scopus 로고    scopus 로고
    • Accessed February 2014. Available
    • The Scottish Intercollegiate Guidelines Network (SIGN). Methodological Guidelines. Accessed February 2014. Available: http://www.sign.ac.uk/ methodology/index.html.
    • Methodological Guidelines
  • 45
    • 84898457085 scopus 로고    scopus 로고
    • Available
    • The National Institute for Health and Care Excellence (2012) The Guidelines Manual 2012. Available: http://www.nice.org.uk/aboutnice/howwework/ developingniceclinicalguidelines/clinicalguidelinedevelopmentmethods/ clinical-guideline-development-methods.jsp.
    • (2012) The Guidelines Manual 2012
  • 47
    • 84972492387 scopus 로고
    • Inference from iterative simulation using multiple sequences
    • Gelman A, Rubin D (1992) Inference from iterative simulation using multiple sequences. Statistical Science 7: 457-511.
    • (1992) Statistical Science , vol.7 , pp. 457-511
    • Gelman, A.1    Rubin, D.2
  • 48
    • 79953311138 scopus 로고    scopus 로고
    • The RESTORE study: Ranibizumab monotherapy or combined with laser versus laser monotherapy for diabetic macular edema
    • Mitchell P, Bandello F, Schmidt-Erfurth U, Lang GE, Massin P, et al. (2011) The RESTORE study: ranibizumab monotherapy or combined with laser versus laser monotherapy for diabetic macular edema. Ophthalmology 118: 615-625.
    • (2011) Ophthalmology , vol.118 , pp. 615-625
    • Mitchell, P.1    Bandello, F.2    Schmidt-Erfurth, U.3    Lang, G.E.4    Massin, P.5
  • 50
    • 84879740382 scopus 로고    scopus 로고
    • Evidence synthesis for decision making 2: A generalized linear modeling framework for pairwise and network meta-analysis of randomized controlled trials
    • Dias S, Sutton AJ, Ades AE, Welton NJ (2013) Evidence synthesis for decision making 2: a generalized linear modeling framework for pairwise and network meta-analysis of randomized controlled trials. Med Decis Making 33: 607-617.
    • (2013) Med Decis Making , vol.33 , pp. 607-617
    • Dias, S.1    Sutton, A.J.2    Ades, A.E.3    Welton, N.J.4
  • 51
    • 84888773229 scopus 로고    scopus 로고
    • Health state utilities in patients with diabetic retinopathy, diabetic macular oedema and age-related macular degeneration: A systematic review
    • Poku E, Brazier J, Carlton J, Ferreira A (2013) Health state utilities in patients with diabetic retinopathy, diabetic macular oedema and age-related macular degeneration: a systematic review. BMC Ophthalmol 13: 74.
    • (2013) BMC Ophthalmol , vol.13 , pp. 74
    • Poku, E.1    Brazier, J.2    Carlton, J.3    Ferreira, A.4
  • 52
    • 84875172451 scopus 로고    scopus 로고
    • Randomized clinical trial evaluating intravitreal ranibizumab or saline for vitreous hemorrhage from proliferative diabetic retinopathy
    • Diabetic Retinopathy Clinical Research Network
    • Diabetic Retinopathy Clinical Research Network (2013) Randomized clinical trial evaluating intravitreal ranibizumab or saline for vitreous hemorrhage from proliferative diabetic retinopathy. JAMA Ophthalmol 131: 283-293.
    • (2013) JAMA Ophthalmol , vol.131 , pp. 283-293
  • 53
    • 84885022258 scopus 로고    scopus 로고
    • Long-term outcomes of ranibizumab therapy for diabetic macular edema: The 36-month results from two phase III trials: RISE and RIDE
    • Brown DM, Nguyen QD, Marcus DM, Boyer DS, Patel S, et al. (2013) Long-term outcomes of ranibizumab therapy for diabetic macular edema: the 36-month results from two phase III trials: RISE and RIDE. Ophthalmology 120: 2013-2022.
    • (2013) Ophthalmology , vol.120 , pp. 2013-2022
    • Brown, D.M.1    Nguyen, Q.D.2    Marcus, D.M.3    Boyer, D.S.4    Patel, S.5
  • 54
    • 84874080959 scopus 로고    scopus 로고
    • Ranibizumab for edema of the macula in diabetes study: 3-year outcomes and the need for prolonged frequent treatment
    • Do DV, Nguyen QD, Khwaja AA, Channa R, Sepah YJ, et al. (2013) Ranibizumab for edema of the macula in diabetes study: 3-year outcomes and the need for prolonged frequent treatment. JAMA Ophthalmol 131: 139-145.
    • (2013) JAMA Ophthalmol , vol.131 , pp. 139-145
    • Do, D.V.1    Nguyen, Q.D.2    Khwaja, A.A.3    Channa, R.4    Sepah, Y.J.5
  • 55
    • 84868208071 scopus 로고    scopus 로고
    • Intravitreal ranibizumab for diabetic macular edema with prompt versus deferred laser treatment: Three-year randomized trial results
    • Elman MJ, Qin H, Aiello LP, Beck RW, Bressler NM, et al. (2012) Intravitreal ranibizumab for diabetic macular edema with prompt versus deferred laser treatment: three-year randomized trial results. Ophthalmology 119: 2312-2318.
    • (2012) Ophthalmology , vol.119 , pp. 2312-2318
    • Elman, M.J.1    Qin, H.2    Aiello, L.P.3    Beck, R.W.4    Bressler, N.M.5
  • 56
    • 84866117381 scopus 로고    scopus 로고
    • Long-term effects of ranibizumab on diabetic retinopathy severity and progression
    • Ip MS, Domalpally A, Hopkins JJ, Wong P, Ehrlich JS (2012) Long-term effects of ranibizumab on diabetic retinopathy severity and progression. Arch Ophthalmol 130: 1145-1152.
    • (2012) Arch Ophthalmol , vol.130 , pp. 1145-1152
    • Ip, M.S.1    Domalpally, A.2    Hopkins, J.J.3    Wong, P.4    Ehrlich, J.S.5
  • 57
    • 84872175978 scopus 로고    scopus 로고
    • Dose-ranging evaluation of intravitreal siRNA PF-04523655 for diabetic macular edema (the DEGAS study)
    • Nguyen QD, Schachar RA, Nduaka CI, Sperling M, Basile AS, et al. (2012) Dose-ranging evaluation of intravitreal siRNA PF-04523655 for diabetic macular edema (the DEGAS study). Invest Ophthalmol Vis Sci 53: 7666-7674.
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 7666-7674
    • Nguyen, Q.D.1    Schachar, R.A.2    Nduaka, C.I.3    Sperling, M.4    Basile, A.S.5
  • 66
    • 84864444516 scopus 로고    scopus 로고
    • One-year outcomes of the da Vinci Study of VEGF Trap-Eye in eyes with diabetic macular edema
    • Do DV, Nguyen QD, Boyer D, Schmidt-Erfurth U, Brown DM, et al. (2012) One-year outcomes of the da Vinci Study of VEGF Trap-Eye in eyes with diabetic macular edema. Ophthalmology 119: 1658-1665.
    • (2012) Ophthalmology , vol.119 , pp. 1658-1665
    • Do, D.V.1    Nguyen, Q.D.2    Boyer, D.3    Schmidt-Erfurth, U.4    Brown, D.M.5
  • 67
    • 77952779304 scopus 로고    scopus 로고
    • Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema
    • Elman MJ, Aiello LP, Beck RW, Bressler NM, Bressler SB, et al. (2010) Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology 117: 1064-1077 e1035.
    • (2010) Ophthalmology , vol.117
    • Elman, M.J.1    Aiello, L.P.2    Beck, R.W.3    Bressler, N.M.4    Bressler, S.B.5
  • 68
    • 79251606719 scopus 로고    scopus 로고
    • Safety and efficacy of ranibizumab in diabetic macular edema (RESOLVE Study): A 12-month, randomized, controlled, double-masked, multicenter phase II study
    • Massin P, Bandello F, Garweg JG, Hansen LL, Harding SP, et al. (2010) Safety and efficacy of ranibizumab in diabetic macular edema (RESOLVE Study): a 12-month, randomized, controlled, double-masked, multicenter phase II study. Diabetes Care 33: 2399-2405.
    • (2010) Diabetes Care , vol.33 , pp. 2399-2405
    • Massin, P.1    Bandello, F.2    Garweg, J.G.3    Hansen, L.L.4    Harding, S.P.5
  • 69
    • 70350567637 scopus 로고    scopus 로고
    • Primary end point (six months) results of the Ranibizumab for Edema of the mAcula in diabetes (READ-2) study
    • Nguyen QD, Shah SM, Heier JS, Do DV, Lim J, et al. (2009) Primary end point (six months) results of the Ranibizumab for Edema of the mAcula in diabetes (READ-2) study. Ophthalmology 116: 2175-2181 e2171.
    • (2009) Ophthalmology , vol.116
    • Nguyen, Q.D.1    Shah, S.M.2    Heier, J.S.3    Do, D.V.4    Lim, J.5
  • 71
    • 84901253883 scopus 로고    scopus 로고
    • The Neovascular Age-Related Macular Degeneration Database: Multicenter study of 92 976 ranibizumab injections: Report 1: Visual acuity
    • Writing Committee for the UK Age-Related Macular Degeneration EMR Users Group
    • Writing Committee for the UK Age-Related Macular Degeneration EMR Users Group (2014) The Neovascular Age-Related Macular Degeneration Database: Multicenter study of 92 976 ranibizumab injections: Report 1: visual acuity. Ophthalmology.
    • (2014) Ophthalmology
  • 72
    • 84904349702 scopus 로고    scopus 로고
    • Regeneron (28 September 2013). Available at
    • Regeneron (2013) IR Conference Call on EYLEA (aflibercept) Injection in Diabetic Macular Edema (28 September 2013). Available at:http://files. shareholder.com/downloads/REGN/2709632625x0x693788/9a16d654-c5c7-44ed-b182- d752da5dab5c/VIVID%20VISTA%20FINAL%20Investor-Handouts-27Sept2013.pdf.
    • (2013) IR Conference Call on EYLEA (Aflibercept) Injection in Diabetic Macular Edema


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.