-
1
-
-
84892649479
-
Standards of medical care in diabetes-2014
-
American Diabetes Association. Standards of medical care in diabetes-2014. Diabetes Care 2014;37(Suppl 1):S14-80
-
(2014)
Diabetes Care
, vol.37
, pp. S14-80
-
-
American Diabetes Association1
-
2
-
-
84881614717
-
Molecular mechanism of action of metformin: Old or new insights?
-
Rena G, Pearson ER, Sakamoto K. Molecular mechanism of action of metformin: old or new insights? Diabetologia 2013;56:1898-906
-
(2013)
Diabetologia
, vol.56
, pp. 1898-1906
-
-
Rena, G.1
Pearson, E.R.2
Sakamoto, K.3
-
3
-
-
84857022479
-
Pre-diabetes, metabolic syndrome, and cardiovascular risk
-
Grundy SM. Pre-diabetes, metabolic syndrome, and cardiovascular risk. J Am Coll Cardiol 2012;59:635-43
-
(2012)
J Am Coll Cardiol
, vol.59
, pp. 635-643
-
-
Grundy, S.M.1
-
4
-
-
84905161219
-
Global burden of cardiovascular disease: Time to implement feasible strategies and to monitor results
-
Fuster V. Global burden of cardiovascular disease: time to implement feasible strategies and to monitor results. J Am Coll Cardiol 2014;64:520-2
-
(2014)
J Am Coll Cardiol
, vol.64
, pp. 520-522
-
-
Fuster, V.1
-
5
-
-
27444443876
-
Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
-
Grundy SM, Cleeman JI, Daniels SR, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005;112:2735-52
-
(2005)
Circulation
, vol.112
, pp. 2735-2752
-
-
Grundy, S.M.1
Cleeman, J.I.2
Daniels, S.R.3
-
7
-
-
84866616996
-
Insulin sensitization therapy and the heart: Focus on metformin and thiazolidinediones
-
Wong AK, Struthers AD, Choy AM, et al. Insulin sensitization therapy and the heart: focus on metformin and thiazolidinediones. Heart Fail Clin 2012;8:539-50
-
(2012)
Heart Fail Clin
, vol.8
, pp. 539-550
-
-
Wong, A.K.1
Struthers, A.D.2
Choy, A.M.3
-
8
-
-
0034659785
-
Evidence that metformin exerts its antidiabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
-
Owen MR, Doran E, Halestrap AP. Evidence that metformin exerts its antidiabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem J 2000;348 Pt 3:607-14
-
(2000)
Biochem J
, vol.348
, pp. 607-614
-
-
Owen, M.R.1
Doran, E.2
Halestrap, A.P.3
-
9
-
-
84858782079
-
AMPK: A nutrient and energy sensor that maintains energy homeostasis
-
Hardie DG, Ross FA, Hawley SA. AMPK: A nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol 2012;13:251-62
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 251-262
-
-
Hardie, D.G.1
Ross, F.A.2
Hawley, S.A.3
-
10
-
-
77956410464
-
Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation
-
Hawley SA, Ross FA, Chevtzoff C, et al. Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation. Cell Metab 2010;11:554-65
-
(2010)
Cell Metab
, vol.11
, pp. 554-565
-
-
Hawley, S.A.1
Ross, F.A.2
Chevtzoff, C.3
-
11
-
-
77954933558
-
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
-
Foretz M, Hebrard S, Leclerc J, et al. Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state. J Clin Invest 2010;120:2355-69
-
(2010)
J Clin Invest
, vol.120
, pp. 2355-2369
-
-
Foretz, M.1
Hebrard, S.2
Leclerc, J.3
-
12
-
-
84873707522
-
Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP
-
Miller RA, Chu Q, Xie J, et al. Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP. Nature 2013;494:256-60
-
(2013)
Nature
, vol.494
, pp. 256-260
-
-
Miller, R.A.1
Chu, Q.2
Xie, J.3
-
13
-
-
33644747421
-
Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase
-
Davis BJ, Xie Z, Viollet B, et al. Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase. Diabetes 2006;55:496-505
-
(2006)
Diabetes
, vol.55
, pp. 496-505
-
-
Davis, B.J.1
Xie, Z.2
Viollet, B.3
-
14
-
-
19444380162
-
Metformin decreases intracellular production of reactive oxygen species in aortic endothelial cells
-
Ouslimani N, Peynet J, Bonnefont-Rousselot D, et al. Metformin decreases intracellular production of reactive oxygen species in aortic endothelial cells. Metabolism 2005;54:829-34
-
(2005)
Metabolism
, vol.54
, pp. 829-834
-
-
Ouslimani, N.1
Peynet, J.2
Bonnefont-Rousselot, D.3
-
16
-
-
38849184562
-
Meta-analysis: Metformin treatment in persons at risk for diabetes mellitus
-
Salpeter SR, Buckley NS, Kahn JA, et al. Meta-analysis: metformin treatment in persons at risk for diabetes mellitus. Am J Med 2008;121:149-57.e2
-
(2008)
Am J Med
, vol.121
, pp. 149-149e2
-
-
Salpeter, S.R.1
Buckley, N.S.2
Kahn, J.A.3
-
17
-
-
77953888154
-
Assessment of nonischemic myocardial fibrosis
-
Jellis C, Martin J, Narula J, et al. Assessment of nonischemic myocardial fibrosis. J Am Coll Cardiol 2010;56:89-97
-
(2010)
J Am Coll Cardiol
, vol.56
, pp. 89-97
-
-
Jellis, C.1
Martin, J.2
Narula, J.3
-
18
-
-
84863848758
-
Integrated backscatter as a fibrosis marker in the metabolic syndrome: Association with biochemical evidence of fibrosis and left ventricular dysfunction
-
Kosmala W, Przewlocka-Kosmala M, Wojnalowicz A, et al. Integrated backscatter as a fibrosis marker in the metabolic syndrome: association with biochemical evidence of fibrosis and left ventricular dysfunction. Eur Heart J Cardiovasc Imaging 2012;13:459-67
-
(2012)
Eur Heart J Cardiovasc Imaging
, vol.13
, pp. 459-467
-
-
Kosmala, W.1
Przewlocka-Kosmala, M.2
Wojnalowicz, A.3
-
19
-
-
34347352169
-
Diabetic cardiomyopathy revisited
-
Boudina S, Abel ED. Diabetic cardiomyopathy revisited. Circulation 2007;115:3213-23
-
(2007)
Circulation
, vol.115
, pp. 3213-3223
-
-
Boudina, S.1
Abel, E.D.2
-
20
-
-
79959790179
-
Heart in diabetes: Not only a macrovascular disease
-
Stratmann B, Tschoepe D. Heart in diabetes: not only a macrovascular disease. Diabetes Care 2011;34(Suppl 2):S138-44
-
(2011)
Diabetes Care
, vol.34
, pp. S138-S144
-
-
Stratmann, B.1
Tschoepe, D.2
-
21
-
-
0034003574
-
Alteration in left ventricular diastolic filling and accumulation of myocardial collagen at insulin-resistant prediabetic stage of a type II diabetic rat model
-
Mizushige K, Yao L, Noma T, et al. Alteration in left ventricular diastolic filling and accumulation of myocardial collagen at insulin-resistant prediabetic stage of a type II diabetic rat model. Circulation 2000;101:899-907
-
(2000)
Circulation
, vol.101
, pp. 899-907
-
-
Mizushige, K.1
Yao, L.2
Noma, T.3
-
22
-
-
34548385838
-
Cardiac steatosis in diabetes mellitus: A 1H-magnetic resonance spectroscopy study
-
McGavock JM, Lingvay I, Zib I, et al. Cardiac steatosis in diabetes mellitus: A 1H-magnetic resonance spectroscopy study. Circulation 2007;116:1170-5
-
(2007)
Circulation
, vol.116
, pp. 1170-1175
-
-
McGavock, J.M.1
Lingvay, I.2
Zib, I.3
-
23
-
-
44749086042
-
Association between diabetes mellitus and left ventricular hypertrophy in a multiethnic population
-
Eguchi K, Boden-Albala B, Jin Z, et al. Association between diabetes mellitus and left ventricular hypertrophy in a multiethnic population. Am J Cardiol 2008;101:1787-91
-
(2008)
Am J Cardiol
, vol.101
, pp. 1787-1791
-
-
Eguchi, K.1
Boden-Albala, B.2
Jin, Z.3
-
24
-
-
70449670815
-
Subclinical left ventricular dysfunction in asymptomatic diabetic patients assessed by two-dimensional speckle tracking echocardiography: Correlation with diabetic duration
-
Nakai H, Takeuchi M, Nishikage T, et al. Subclinical left ventricular dysfunction in asymptomatic diabetic patients assessed by two-dimensional speckle tracking echocardiography: correlation with diabetic duration. Euro J Echocardiogr 2009;10:926-32
-
(2009)
Euro J Echocardiogr
, vol.10
, pp. 926-932
-
-
Nakai, H.1
Takeuchi, M.2
Nishikage, T.3
-
25
-
-
0035252663
-
Prevalence of diastolic dysfunction in normotensive, asymptomatic patients with well-controlled type 2 diabetes mellitus
-
Zabalgoitia M, Ismaeil MF, Anderson L, et al. Prevalence of diastolic dysfunction in normotensive, asymptomatic patients with well-controlled type 2 diabetes mellitus. Am J Cardiol 2001;87:320-3
-
(2001)
Am J Cardiol
, vol.87
, pp. 320-323
-
-
Zabalgoitia, M.1
Ismaeil, M.F.2
Anderson, L.3
-
26
-
-
84877057639
-
Cardiac fibrosis and vascular remodeling are attenuated by metformin in obese rats
-
Burlá AK, Lobato NS, Fortes ZB, et al. Cardiac fibrosis and vascular remodeling are attenuated by metformin in obese rats. Int J Cardiol 2011;165(3):483-7
-
(2011)
Int J Cardiol
, vol.165
, Issue.3
, pp. 483-487
-
-
Burlá, A.K.1
Lobato, N.S.2
Fortes, Z.B.3
-
27
-
-
84859534676
-
Metformin prevents the development of chronic heart failure in the SHHF rat model
-
Cittadini A, Napoli R, Monti MG, et al. Metformin prevents the development of chronic heart failure in the SHHF rat model. Diabetes 2012;61:944-53
-
(2012)
Diabetes
, vol.61
, pp. 944-953
-
-
Cittadini, A.1
Napoli, R.2
Monti, M.G.3
-
28
-
-
77954777802
-
Metformin attenuates cardiac fibrosis by inhibiting the TGFbeta1-Smad3 signalling pathway
-
Xiao H, Ma X, Feng W, et al. Metformin attenuates cardiac fibrosis by inhibiting the TGFbeta1-Smad3 signalling pathway. Cardiovasc Res 2010;87:504-13
-
(2010)
Cardiovasc Res
, vol.87
, pp. 504-513
-
-
Xiao, H.1
Ma, X.2
Feng, W.3
-
29
-
-
78650658243
-
Metformin attenuates ventricular hypertrophy by activating the AMP-activated protein kinase-endothelial nitric oxide synthase pathway in rats
-
Zhang CX, Pan SN, Meng RS, et al. Metformin attenuates ventricular hypertrophy by activating the AMP-activated protein kinase-endothelial nitric oxide synthase pathway in rats. Clin Exp Pharmacol Physiol 2011;38:55-62
-
(2011)
Clin Exp Pharmacol Physiol
, vol.38
, pp. 55-62
-
-
Zhang, C.X.1
Pan, S.N.2
Meng, R.S.3
-
30
-
-
84924331804
-
Diastolic dysfunction in the diabetic continuum : Association with insulin resistance, metabolic syndrome and type 2 diabetes
-
Fontes-Carvalho R, Ladeiras-Lopes R, Bettencourt P, et al. Diastolic dysfunction in the diabetic continuum : association with insulin resistance, metabolic syndrome and type 2 diabetes. Cardiovasc Diabetol 2015;14:4
-
(2015)
Cardiovasc Diabetol
, vol.14
, pp. 4
-
-
Fontes-Carvalho, R.1
Ladeiras-Lopes, R.2
Bettencourt, P.3
-
31
-
-
84897103582
-
METformin in DIastolic Dysfunction of Metabolic syndrome (MET-DIME) trial: Rationale and study design : Rial
-
Ladeiras-Lopes R, Fontes-Carvalho R, Bettencourt N, et al. METformin in DIastolic Dysfunction of Metabolic syndrome (MET-DIME) trial: rationale and study design : MET-DIME trial. Cardiovasc Drugs Ther 2014;28:191-6
-
(2014)
Cardiovasc Drugs Ther
, vol.28
, pp. 191-196
-
-
Ladeiras-Lopes, R.1
Fontes-Carvalho, R.2
Bettencourt, N.3
-
32
-
-
84906882822
-
Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: A systematic analysis for the Global Burden of Disease Study 2013
-
Ng M, Fleming T, Robinson M, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: A systematic analysis for the Global Burden of Disease Study 2013. Lancet 2014;384:766-81
-
(2014)
Lancet
, vol.384
, pp. 766-781
-
-
Ng, M.1
Fleming, T.2
Robinson, M.3
-
33
-
-
79952674321
-
Effect of obesity and overweight on left ventricular diastolic function: A community-based study in an elderly cohort
-
Russo C, Jin Z, Homma S, et al. Effect of obesity and overweight on left ventricular diastolic function: A community-based study in an elderly cohort. J Am Coll Cardiol 2011;57:1368-74
-
(2011)
J Am Coll Cardiol
, vol.57
, pp. 1368-1374
-
-
Russo, C.1
Jin, Z.2
Homma, S.3
-
34
-
-
84877935534
-
Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure
-
Lavie CJ, Alpert MA, Arena R, et al. Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure. JACC Heart Fail 2013;1:93-102
-
(2013)
JACC Heart Fail
, vol.1
, pp. 93-102
-
-
Lavie, C.J.1
Alpert, M.A.2
Arena, R.3
-
35
-
-
33745148603
-
Association of obesity with left ventricular remodeling and diastolic dysfunction in patients without coronary artery disease
-
Powell BD, Redfield MM, Bybee KA, et al. Association of obesity with left ventricular remodeling and diastolic dysfunction in patients without coronary artery disease. J Am Coll Cardiol 2006;98:116-20
-
(2006)
J Am Coll Cardiol
, vol.98
, pp. 116-120
-
-
Powell, B.D.1
Redfield, M.M.2
Bybee, K.A.3
-
36
-
-
52049112608
-
Leptin: Linking obesity, the metabolic syndrome, and cardiovascular disease
-
Patel SB, Reams GP, Spear RM, et al. Leptin: linking obesity, the metabolic syndrome, and cardiovascular disease. Curr Hypertens Rep 2008;10:131-7
-
(2008)
Curr Hypertens Rep
, vol.10
, pp. 131-137
-
-
Patel, S.B.1
Reams, G.P.2
Spear, R.M.3
-
37
-
-
84861762003
-
Inflammation and metabolic dysfunction: Links to cardiovascular diseases
-
Taube A, Schlich R, Sell H, et al. Inflammation and metabolic dysfunction: links to cardiovascular diseases. Am J Physiol Heart Circ Physiol 2012;302:H2148-65
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.302
, pp. H2148-H2165
-
-
Taube, A.1
Schlich, R.2
Sell, H.3
-
38
-
-
84880974817
-
Adipokines mediate inflammation and insulin resistance
-
Kwon H, Pessin JE. Adipokines mediate inflammation and insulin resistance. Front Endocrinol 2013;4:71
-
(2013)
Front Endocrinol
, vol.4
, pp. 71
-
-
Kwon, H.1
Pessin, J.E.2
-
39
-
-
17544382289
-
AdipoQ is a novel adipose-specific gene dysregulated in obesity
-
Hu E, Liang P, Spiegelman BM. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 1996;271:10697-703
-
(1996)
J Biol Chem
, vol.271
, pp. 10697-10703
-
-
Hu, E.1
Liang, P.2
Spiegelman, B.M.3
-
40
-
-
0033515761
-
Paradoxical decrease of an adiposespecific protein, adiponectin, in obesity
-
Arita Y, Kihara S, Ouchi N, et al. Paradoxical decrease of an adiposespecific protein, adiponectin, in obesity. Biochem Biophys Res Commun 1999;257:79-83
-
(1999)
Biochem Biophys Res Commun
, vol.257
, pp. 79-83
-
-
Arita, Y.1
Kihara, S.2
Ouchi, N.3
-
41
-
-
13244284806
-
Adiponectin-journey from an adipocyte secretory protein to biomarker of the metabolic syndrome
-
Trujillo ME, Scherer PE. Adiponectin-journey from an adipocyte secretory protein to biomarker of the metabolic syndrome. J Int Med 2005;257:167-75
-
(2005)
J Int Med
, vol.257
, pp. 167-175
-
-
Trujillo, M.E.1
Scherer, P.E.2
-
42
-
-
77957579585
-
Molecular mechanisms of signal transduction via adiponectin and adiponectin receptors
-
Heiker JT, Kosel D, Beck-Sickinger AG. Molecular mechanisms of signal transduction via adiponectin and adiponectin receptors. Biol Chem 2010;391:1005-18
-
(2010)
Biol Chem
, vol.391
, pp. 1005-1018
-
-
Heiker, J.T.1
Kosel, D.2
Beck-Sickinger, A.G.3
-
43
-
-
33744972277
-
APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function
-
Mao X, Kikani CK, Riojas RA, et al. APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function. Nat Cell Biol 2006;8:516-23
-
(2006)
Nat Cell Biol
, vol.8
, pp. 516-523
-
-
Mao, X.1
Kikani, C.K.2
Riojas, R.A.3
-
44
-
-
79951683323
-
Globular and full-length adiponectin induce NO-dependent vasodilation in resistance arteries of Zucker lean but not Zucker diabetic fatty rats
-
Schmid PM, Resch M, Steege A, et al. Globular and full-length adiponectin induce NO-dependent vasodilation in resistance arteries of Zucker lean but not Zucker diabetic fatty rats. Am J Hypertens 2011;24:270-7
-
(2011)
Am J Hypertens
, vol.24
, pp. 270-277
-
-
Schmid, P.M.1
Resch, M.2
Steege, A.3
-
45
-
-
84875016899
-
Antidiabetic treatment restores adiponectin serum levels and APPL1 expression, but does not improve adiponectin-induced vasodilation and endothelial dysfunction in Zucker diabetic fatty rats
-
Schmid PM, Resch M, Schach C, et al. Antidiabetic treatment restores adiponectin serum levels and APPL1 expression, but does not improve adiponectin-induced vasodilation and endothelial dysfunction in Zucker diabetic fatty rats. Cardiovasc Diabetol 2013;12:46
-
(2013)
Cardiovasc Diabetol
, vol.12
, pp. 46
-
-
Schmid, P.M.1
Resch, M.2
Schach, C.3
-
46
-
-
84858196211
-
The effects of metformin on inflammatory mediators in obese adolescents with insulin resistance: Controlled randomized clinical trial
-
Evia-Viscarra ML, Rodea-Montero ER, Apolinar-Jimenez E, et al. The effects of metformin on inflammatory mediators in obese adolescents with insulin resistance: controlled randomized clinical trial. J Pediatr Endocrinol Metab 2012;25:41-9
-
(2012)
J Pediatr Endocrinol Metab
, vol.25
, pp. 41-49
-
-
Evia-Viscarra, M.L.1
Rodea-Montero, E.R.2
Apolinar-Jimenez, E.3
-
47
-
-
0032511566
-
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group
-
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet 1998;352:854-65
-
(1998)
Lancet
, vol.352
, pp. 854-865
-
-
-
48
-
-
40949087724
-
Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling
-
Calvert JW, Gundewar S, Jha S, et al. Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling. Diabetes 2008;57:696-705
-
(2008)
Diabetes
, vol.57
, pp. 696-705
-
-
Calvert, J.W.1
Gundewar, S.2
Jha, S.3
-
49
-
-
61949300140
-
Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure
-
Gundewar S, Calvert JW, Jha S, et al. Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure. Circ Res 2009;104:403-11
-
(2009)
Circ Res
, vol.104
, pp. 403-411
-
-
Gundewar, S.1
Calvert, J.W.2
Jha, S.3
-
50
-
-
84897065063
-
Chronic metformin treatment is associated with reduced myocardial infarct size in diabetic patients with STsegment elevation myocardial infarction
-
Lexis CP, Wieringa WG, Hiemstra B, et al. Chronic metformin treatment is associated with reduced myocardial infarct size in diabetic patients with STsegment elevation myocardial infarction. Cardiovasc Drugs Ther 2014;28:163-71
-
(2014)
Cardiovasc Drugs Ther
, vol.28
, pp. 163-171
-
-
Lexis, C.P.1
Wieringa, W.G.2
Hiemstra, B.3
-
51
-
-
42249101542
-
Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening
-
Bhamra GS, Hausenloy DJ, Davidson SM, et al. Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening. Basic Res Cardiol 2008;103:274-84
-
(2008)
Basic Res Cardiol
, vol.103
, pp. 274-284
-
-
Bhamra, G.S.1
Hausenloy, D.J.2
Davidson, S.M.3
-
52
-
-
0037383432
-
The mitochondrial permeability transition pore: Its fundamental role in mediating cell death during ischaemia and reperfusion
-
Hausenloy DJ, Yellon DM. The mitochondrial permeability transition pore: its fundamental role in mediating cell death during ischaemia and reperfusion. J Mol Cell Cardiol 2003;35:339-41
-
(2003)
J Mol Cell Cardiol
, vol.35
, pp. 339-341
-
-
Hausenloy, D.J.1
Yellon, D.M.2
-
53
-
-
67650921900
-
Metformin prevents myocardial reperfusion injury by activating the adenosine receptor
-
Paiva M, Riksen NP, Davidson SM, et al. Metformin prevents myocardial reperfusion injury by activating the adenosine receptor. J Cardiovasc Pharmacol 2009;53:373-8
-
(2009)
J Cardiovasc Pharmacol
, vol.53
, pp. 373-378
-
-
Paiva, M.1
Riksen, N.P.2
Davidson, S.M.3
-
54
-
-
0033841763
-
Insulin administered at reoxygenation exerts a cardioprotective effect in myocytes by a possible anti-apoptotic mechanism
-
Jonassen AK, Brar BK, Mjos OD, et al. Insulin administered at reoxygenation exerts a cardioprotective effect in myocytes by a possible anti-apoptotic mechanism. J Mol Cell Cardiol 2000;32:757-64
-
(2000)
J Mol Cell Cardiol
, vol.32
, pp. 757-764
-
-
Jonassen, A.K.1
Brar, B.K.2
Mjos, O.D.3
-
55
-
-
0035824907
-
Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling
-
Jonassen AK, Sack MN, Mjos OD, et al. Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling. Circ Res 2001;89:1191-8
-
(2001)
Circ Res
, vol.89
, pp. 1191-1198
-
-
Jonassen, A.K.1
Sack, M.N.2
Mjos, O.D.3
-
56
-
-
0037177142
-
Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemiareperfusion: The roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation
-
Gao F, Gao E, Yue TL, et al. Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemiareperfusion: The roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation. Circulation 2002;105:1497-502
-
(2002)
Circulation
, vol.105
, pp. 1497-1502
-
-
Gao, F.1
Gao, E.2
Yue, T.L.3
-
57
-
-
84898607351
-
Effect of metformin on left ventricular function after acute myocardial infarction in patients without diabetes: The GIPS-III randomized clinical trial
-
Lexis CP, van der Horst IC, Lipsic E, et al. Effect of metformin on left ventricular function after acute myocardial infarction in patients without diabetes: The GIPS-III randomized clinical trial. JAMA 2014;311:1526-35
-
(2014)
JAMA
, vol.311
, pp. 1526-1535
-
-
Lexis, C.P.1
Van Der Horst, I.C.2
Lipsic, E.3
-
58
-
-
76149144326
-
Metformin reduces arterial stiffness and improves endothelial function in young women with polycystic ovary syndrome: A randomized, placebo-controlled, crossover trial
-
Agarwal N, Rice SP, Bolusani H, et al. Metformin reduces arterial stiffness and improves endothelial function in young women with polycystic ovary syndrome: A randomized, placebo-controlled, crossover trial. J Clin Endocrinol Metab 2010;95:722-30
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 722-730
-
-
Agarwal, N.1
Rice, S.P.2
Bolusani, H.3
-
59
-
-
84863492238
-
Effect of insulin sensitizer therapy on atherothrombotic and inflammatory profiles associated with insulin resistance
-
McCoy RG, Irving BA, Soop M, et al. Effect of insulin sensitizer therapy on atherothrombotic and inflammatory profiles associated with insulin resistance. Mayo Clin Proc 2012;87:561-70
-
(2012)
Mayo Clin Proc
, vol.87
, pp. 561-570
-
-
McCoy, R.G.1
Irving, B.A.2
Soop, M.3
-
60
-
-
0024533040
-
Study of the effect of metformin on platelet aggregation in insulin-dependent diabetics
-
Gin H, Freyburger G, Boisseau M, et al. Study of the effect of metformin on platelet aggregation in insulin-dependent diabetics. Diabetes Res Clin Pract 1989;6:61-7
-
(1989)
Diabetes Res Clin Pract
, vol.6
, pp. 61-67
-
-
Gin, H.1
Freyburger, G.2
Boisseau, M.3
-
61
-
-
0027399661
-
Effects of metformin on insulin resistance, risk factors for cardiovascular disease, and plasminogen activator inhibitor in NIDDM subjects. A study of two ethnic groups
-
Nagi DK, Yudkin JS. Effects of metformin on insulin resistance, risk factors for cardiovascular disease, and plasminogen activator inhibitor in NIDDM subjects. A study of two ethnic groups. Diabetes care 1993;16:621-9
-
(1993)
Diabetes Care
, vol.16
, pp. 621-629
-
-
Nagi, D.K.1
Yudkin, J.S.2
-
62
-
-
0030175581
-
Vascular effects of metformin. Possible mechanisms for its antihypertensive action in the spontaneously hypertensive rat
-
Bhalla RC, Toth KF, Tan E, et al. Vascular effects of metformin. Possible mechanisms for its antihypertensive action in the spontaneously hypertensive rat. Am J Hypertens 1996;9:570-6
-
(1996)
Am J Hypertens
, vol.9
, pp. 570-576
-
-
Bhalla, R.C.1
Toth, K.F.2
Tan, E.3
-
64
-
-
84862776132
-
Metformin-based treatment for obesityrelated hypertension: A randomized, double-blind, placebo-controlled trial
-
He H, Zhao Z, Chen J, et al. Metformin-based treatment for obesityrelated hypertension: A randomized, double-blind, placebo-controlled trial. J Hypertens 2012;30:1430-9
-
(2012)
J Hypertens
, vol.30
, pp. 1430-1439
-
-
He, H.1
Zhao, Z.2
Chen, J.3
-
65
-
-
84931075385
-
-
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