-
1
-
-
84860806316
-
Pancreatic cancer: between bench and bedside
-
Melisi D and Budillon A. Pancreatic cancer: between bench and bedside Current drug targets. 2012; 13(6):729-730.
-
(2012)
Current drug targets.
, vol.13
, Issue.6
, pp. 729-730
-
-
Melisi, D.1
Budillon, A.2
-
3
-
-
84881523670
-
Mechanisms of resistance to chemotherapeutic and antiangiogenic drugs as novel targets for pancreatic cancer therapy
-
Tamburrino A, Piro G, Carbone C, Tortora G and Melisi D. Mechanisms of resistance to chemotherapeutic and antiangiogenic drugs as novel targets for pancreatic cancer therapy. Frontiers in pharmacology. 2013; 4:56.
-
(2013)
Frontiers in pharmacology.
, vol.4
, pp. 56
-
-
Tamburrino, A.1
Piro, G.2
Carbone, C.3
Tortora, G.4
Melisi, D.5
-
4
-
-
77951709577
-
Preoperative/neoadjuvant therapy in pancreatic cancer: a systematic review and meta-analysis of response and resection percentages
-
Gillen S, Schuster T, Meyer Zum Buschenfelde C, Friess H and Kleeff J. Preoperative/neoadjuvant therapy in pancreatic cancer: a systematic review and meta-analysis of response and resection percentages PLoS Med. 2010; 7(4):e1000267.
-
(2010)
PLoS Med.
, vol.7
, Issue.4
, pp. e1000267
-
-
Gillen, S.1
Schuster, T.2
Meyer Zum Buschenfelde, C.3
Friess, H.4
Kleeff, J.5
-
5
-
-
77956416112
-
Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: a randomized controlled trial
-
Neoptolemos JP, Stocken DD, Bassi C, Ghaneh P, Cunningham D, Goldstein D, Padbury R, Moore MJ, Gallinger S, Mariette C, Wente MN, Izbicki JR, Friess H, Lerch MM, Dervenis C, Olah A, et al. Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: a randomized controlled trial Jama. 2010; 304(10):1073-1081.
-
(2010)
Jama.
, vol.304
, Issue.10
, pp. 1073-1081
-
-
Neoptolemos, J.P.1
Stocken, D.D.2
Bassi, C.3
Ghaneh, P.4
Cunningham, D.5
Goldstein, D.6
Padbury, R.7
Moore, M.J.8
Gallinger, S.9
Mariette, C.10
Wente, M.N.11
Izbicki, J.R.12
Friess, H.13
Lerch, M.M.14
Dervenis, C.15
Olah, A.16
-
6
-
-
84865076498
-
Genetic basis of pancreas cancer development and progression: insights from whole-exome and wholegenome sequencing
-
Iacobuzio-Donahue CA, Velculescu VE, Wolfgang CL and Hruban RH. Genetic basis of pancreas cancer development and progression: insights from whole-exome and wholegenome sequencing Clin Cancer Res. 2012; 18(16):4257-4265.
-
(2012)
Clin Cancer Res.
, vol.18
, Issue.16
, pp. 4257-4265
-
-
Iacobuzio-Donahue, C.A.1
Velculescu, V.E.2
Wolfgang, C.L.3
Hruban, R.H.4
-
7
-
-
84862777152
-
Presence of somatic mutations in most earlystage pancreatic intraepithelial neoplasia
-
Kanda M, Matthaei H, Wu J, Hong SM, Yu J, Borges M, Hruban RH, Maitra A, Kinzler K, Vogelstein B and Goggins M. Presence of somatic mutations in most earlystage pancreatic intraepithelial neoplasia Gastroenterology. 2012; 142(4):730-733 e739.
-
(2012)
Gastroenterology.
, vol.142
, Issue.4
, pp. 730-733 e739
-
-
Kanda, M.1
Matthaei, H.2
Wu, J.3
Hong, S.M.4
Yu, J.5
Borges, M.6
Hruban, R.H.7
Maitra, A.8
Kinzler, K.9
Vogelstein, B.10
Goggins, M.11
-
8
-
-
84861574101
-
Genetic evolution of pancreatic cancer: lessons learnt from the pancreatic cancer genome sequencing project
-
Iacobuzio-Donahue CA. Genetic evolution of pancreatic cancer: lessons learnt from the pancreatic cancer genome sequencing project Gut. 2012; 61(7):1085-1094.
-
(2012)
Gut.
, vol.61
, Issue.7
, pp. 1085-1094
-
-
Iacobuzio-Donahue, C.A.1
-
9
-
-
84887425166
-
Evolution and dynamics of pancreatic cancer progression
-
Yachida S and Iacobuzio-Donahue CA. Evolution and dynamics of pancreatic cancer progression Oncogene. 2013; 32(45):5253-5260.
-
(2013)
Oncogene.
, vol.32
, Issue.45
, pp. 5253-5260
-
-
Yachida, S.1
Iacobuzio-Donahue, C.A.2
-
10
-
-
78049398107
-
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
-
Yachida S, Jones S, Bozic I, Antal T, Leary R, Fu B, Kamiyama M, Hruban RH, Eshleman JR, Nowak MA, Velculescu VE, Kinzler KW, Vogelstein B and Iacobuzio-Donahue CA. Distant metastasis occurs late during the genetic evolution of pancreatic cancer Nature. 2010; 467(7319):1114-1117.
-
(2010)
Nature.
, vol.467
, Issue.7319
, pp. 1114-1117
-
-
Yachida, S.1
Jones, S.2
Bozic, I.3
Antal, T.4
Leary, R.5
Fu, B.6
Kamiyama, M.7
Hruban, R.H.8
Eshleman, J.R.9
Nowak, M.A.10
Velculescu, V.E.11
Kinzler, K.W.12
Vogelstein, B.13
Iacobuzio-Donahue, C.A.14
-
11
-
-
84856082746
-
Computational modeling of pancreatic cancer reveals kinetics of metastasis suggesting optimum treatment strategies
-
Haeno H, Gonen M, Davis MB, Herman JM, Iacobuzio-Donahue CA and Michor F. Computational modeling of pancreatic cancer reveals kinetics of metastasis suggesting optimum treatment strategies Cell. 2012; 148(1-2):362-375.
-
(2012)
Cell.
, vol.148
, Issue.1-2
, pp. 362-375
-
-
Haeno, H.1
Gonen, M.2
Davis, M.B.3
Herman, J.M.4
Iacobuzio-Donahue, C.A.5
Michor, F.6
-
12
-
-
84856088337
-
EMT and dissemination precede pancreatic tumor formation
-
Rhim AD, Mirek ET, Aiello NM, Maitra A, Bailey JM, McAllister F, Reichert M, Beatty GL, Rustgi AK, Vonderheide RH, Leach SD and Stanger BZ. EMT and dissemination precede pancreatic tumor formation Cell. 2012; 148(1-2):349-361.
-
(2012)
Cell.
, vol.148
, Issue.1-2
, pp. 349-361
-
-
Rhim, A.D.1
Mirek, E.T.2
Aiello, N.M.3
Maitra, A.4
Bailey, J.M.5
McAllister, F.6
Reichert, M.7
Beatty, G.L.8
Rustgi, A.K.9
Vonderheide, R.H.10
Leach, S.D.11
Stanger, B.Z.12
-
14
-
-
0033543751
-
Molecular cloning, expression, and characterization of angiopoietin-related protein angiopoietin-related protein induces endothelial cell sprouting
-
Kim I, Moon SO, Koh KN, Kim H, Uhm CS, Kwak HJ, Kim NG and Koh GY. Molecular cloning, expression, and characterization of angiopoietin-related protein angiopoietin-related protein induces endothelial cell sprouting. J Biol Chem. 1999; 274(37):26523-26528.
-
(1999)
J Biol Chem.
, vol.274
, Issue.37
, pp. 26523-26528
-
-
Kim, I.1
Moon, S.O.2
Koh, K.N.3
Kim, H.4
Uhm, C.S.5
Kwak, H.J.6
Kim, N.G.7
Koh, G.Y.8
-
15
-
-
69149090011
-
Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance
-
Tabata M, Kadomatsu T, Fukuhara S, Miyata K, Ito Y, Endo M, Urano T, Zhu HJ, Tsukano H, Tazume H, Kaikita K, Miyashita K, Iwawaki T, Shimabukuro M, Sakaguchi K, Ito T, et al. Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance Cell metabolism. 2009; 10(3):178-188.
-
(2009)
Cell metabolism.
, vol.10
, Issue.3
, pp. 178-188
-
-
Tabata, M.1
Kadomatsu, T.2
Fukuhara, S.3
Miyata, K.4
Ito, Y.5
Endo, M.6
Urano, T.7
Zhu, H.J.8
Tsukano, H.9
Tazume, H.10
Kaikita, K.11
Miyashita, K.12
Iwawaki, T.13
Shimabukuro, M.14
Sakaguchi, K.15
Ito, T.16
-
16
-
-
84255192073
-
Angiopoietinlike protein 2 is an important facilitator of inflammatory carcinogenesis and metastasis
-
Aoi J, Endo M, Kadomatsu T, Miyata K, Nakano M, Horiguchi H, Ogata A, Odagiri H, Yano M, Araki K, Jinnin M, Ito T, Hirakawa S, Ihn H and Oike Y. Angiopoietinlike protein 2 is an important facilitator of inflammatory carcinogenesis and metastasis Cancer Res. 2011; 71(24):7502-7512.
-
(2011)
Cancer Res.
, vol.71
, Issue.24
, pp. 7502-7512
-
-
Aoi, J.1
Endo, M.2
Kadomatsu, T.3
Miyata, K.4
Nakano, M.5
Horiguchi, H.6
Ogata, A.7
Odagiri, H.8
Yano, M.9
Araki, K.10
Jinnin, M.11
Ito, T.12
Hirakawa, S.13
Ihn, H.14
Oike, Y.15
-
17
-
-
80052453669
-
Anti-VEGF Treatment Resistant Pancreatic Cancers Secrete Proinflammatory Factors that Contribute to Malignant Progression by Inducing an EMT cell phenotype
-
Carbone C, Moccia T, Zhu C, Paradiso G, Budillon A, Chiao P, Abbruzzese JL and Melisi D. Anti-VEGF Treatment Resistant Pancreatic Cancers Secrete Proinflammatory Factors that Contribute to Malignant Progression by Inducing an EMT cell phenotype. Clin Cancer Res. 2011.
-
(2011)
Clin Cancer Res
-
-
Carbone, C.1
Moccia, T.2
Zhu, C.3
Paradiso, G.4
Budillon, A.5
Chiao, P.6
Abbruzzese, J.L.7
Melisi, D.8
-
18
-
-
84863772695
-
Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development
-
Zheng J, Umikawa M, Cui C, Li J, Chen X, Zhang C, Huynh H, Kang X, Silvany R, Wan X, Ye J, Canto AP, Chen SH, Wang HY, Ward ES and Zhang CC. Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development Nature. 2012; 485(7400):656-660.
-
(2012)
Nature.
, vol.485
, Issue.7400
, pp. 656-660
-
-
Zheng, J.1
Umikawa, M.2
Cui, C.3
Li, J.4
Chen, X.5
Zhang, C.6
Huynh, H.7
Kang, X.8
Silvany, R.9
Wan, X.10
Ye, J.11
Canto, A.P.12
Chen, S.H.13
Wang, H.Y.14
Ward, E.S.15
Zhang, C.C.16
-
19
-
-
84904327508
-
Cooperativity of oncogenic K-ras and downregulated p16/ INK4A in human pancreatic tumorigenesis
-
Chang Z, Ju H, Ling J, Zhuang Z, Li Z, Wang H, Fleming JB, Freeman JW, Yu D, Huang P and Chiao PJ. Cooperativity of oncogenic K-ras and downregulated p16/ INK4A in human pancreatic tumorigenesis PLoS One. 2014; 9(7):e101452.
-
(2014)
PLoS One.
, vol.9
, Issue.7
, pp. e101452
-
-
Chang, Z.1
Ju, H.2
Ling, J.3
Zhuang, Z.4
Li, Z.5
Wang, H.6
Fleming, J.B.7
Freeman, J.W.8
Yu, D.9
Huang, P.10
Chiao, P.J.11
-
20
-
-
67650999875
-
The basics of epithelialmesenchymal transition
-
Kalluri R and Weinberg RA. The basics of epithelialmesenchymal transition J Clin Invest. 2009; 119(6):1420-1428.
-
(2009)
J Clin Invest.
, vol.119
, Issue.6
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
21
-
-
84896737110
-
Angiopoietin-like protein 2 accelerates carcinogenesis by activating chronic inflammation and oxidative stress
-
Aoi J, Endo M, Kadomatsu T, Miyata K, Ogata A, Horiguchi H, Odagiri H, Masuda T, Fukushima S, Jinnin M, Hirakawa S, Sawa T, Akaike T, Ihn H and Oike Y. Angiopoietin-like protein 2 accelerates carcinogenesis by activating chronic inflammation and oxidative stress Mol Cancer Res. 2014; 12(2):239-249.
-
(2014)
Mol Cancer Res.
, vol.12
, Issue.2
, pp. 239-249
-
-
Aoi, J.1
Endo, M.2
Kadomatsu, T.3
Miyata, K.4
Ogata, A.5
Horiguchi, H.6
Odagiri, H.7
Masuda, T.8
Fukushima, S.9
Jinnin, M.10
Hirakawa, S.11
Sawa, T.12
Akaike, T.13
Ihn, H.14
Oike, Y.15
-
22
-
-
84859377402
-
Tumor cell-derived angiopoietin-like protein ANGPTL2 is a critical driver of metastasis
-
Endo M, Nakano M, Kadomatsu T, Fukuhara S, Kuroda H, Mikami S, Hato T, Aoi J, Horiguchi H, Miyata K, Odagiri H, Masuda T, Harada M, Horio H, Hishima T, Nomori H, et al. Tumor cell-derived angiopoietin-like protein ANGPTL2 is a critical driver of metastasis Cancer Res. 2012; 72(7):1784-1794.
-
(2012)
Cancer Res.
, vol.72
, Issue.7
, pp. 1784-1794
-
-
Endo, M.1
Nakano, M.2
Kadomatsu, T.3
Fukuhara, S.4
Kuroda, H.5
Mikami, S.6
Hato, T.7
Aoi, J.8
Horiguchi, H.9
Miyata, K.10
Odagiri, H.11
Masuda, T.12
Harada, M.13
Horio, H.14
Hishima, T.15
Nomori, H.16
-
23
-
-
84893040697
-
The secreted protein ANGPTL2 promotes metastasis of osteosarcoma cells through integrin alpha5beta1, p38 MAPK, and matrix metalloproteinases
-
Odagiri H, Kadomatsu T, Endo M, Masuda T, Morioka MS, Fukuhara S, Miyamoto T, Kobayashi E, Miyata K, Aoi J, Horiguchi H, Nishimura N, Terada K, Yakushiji T, Manabe I, Mochizuki N, et al. The secreted protein ANGPTL2 promotes metastasis of osteosarcoma cells through integrin alpha5beta1, p38 MAPK, and matrix metalloproteinases Science signaling. 2014; 7(309):ra7.
-
(2014)
Science signaling.
, vol.7
, Issue.309
, pp. ra7
-
-
Odagiri, H.1
Kadomatsu, T.2
Endo, M.3
Masuda, T.4
Morioka, M.S.5
Fukuhara, S.6
Miyamoto, T.7
Kobayashi, E.8
Miyata, K.9
Aoi, J.10
Horiguchi, H.11
Nishimura, N.12
Terada, K.13
Yakushiji, T.14
Manabe, I.15
Mochizuki, N.16
-
24
-
-
84873341409
-
Deciphering the mechanisms of tumorigenesis in human pancreatic ductal epithelial cells
-
Chang Z, Li Z, Wang X, Kang Y, Yuan Y, Niu J, Wang H, Chatterjee D, Fleming JB, Li M, Abbruzzese JL and Chiao PJ. Deciphering the mechanisms of tumorigenesis in human pancreatic ductal epithelial cells Clin Cancer Res. 2013; 19(3):549-559.
-
(2013)
Clin Cancer Res.
, vol.19
, Issue.3
, pp. 549-559
-
-
Chang, Z.1
Li, Z.2
Wang, X.3
Kang, Y.4
Yuan, Y.5
Niu, J.6
Wang, H.7
Chatterjee, D.8
Fleming, J.B.9
Li, M.10
Abbruzzese, J.L.11
Chiao, P.J.12
-
25
-
-
70350243066
-
Oral poly(ADP-ribose) polymerase-1 inhibitor BSI-401 has antitumor activity and synergizes with oxaliplatin against pancreatic cancer, preventing acute neurotoxicity
-
Melisi D, Ossovskaya V, Zhu C, Rosa R, Ling J, Dougherty PM, Sherman BM, Abbruzzese JL and Chiao PJ. Oral poly(ADP-ribose) polymerase-1 inhibitor BSI-401 has antitumor activity and synergizes with oxaliplatin against pancreatic cancer, preventing acute neurotoxicity Clin Cancer Res. 2009; 15(20):6367-6377.
-
(2009)
Clin Cancer Res.
, vol.15
, Issue.20
, pp. 6367-6377
-
-
Melisi, D.1
Ossovskaya, V.2
Zhu, C.3
Rosa, R.4
Ling, J.5
Dougherty, P.M.6
Sherman, B.M.7
Abbruzzese, J.L.8
Chiao, P.J.9
-
26
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak KJ and Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods. 2001; 25(4):402-408.
-
(2001)
Methods.
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
27
-
-
4444280232
-
Antitumor activity of ZD6126, a novel vascular-targeting agent, is enhanced when combined with ZD1839, an epidermal growth factor receptor tyrosine kinase inhibitor, and potentiates the effects of radiation in a human non-small cell lung cancer xenograft model
-
Raben D, Bianco C, Damiano V, Bianco R, Melisi D, Mignogna C, D'Armiento FP, Cionini L, Bianco AR, Tortora G, Ciardiello F and Bunn P. Antitumor activity of ZD6126, a novel vascular-targeting agent, is enhanced when combined with ZD1839, an epidermal growth factor receptor tyrosine kinase inhibitor, and potentiates the effects of radiation in a human non-small cell lung cancer xenograft model Mol Cancer Ther. 2004; 3(8):977-983.
-
(2004)
Mol Cancer Ther.
, vol.3
, Issue.8
, pp. 977-983
-
-
Raben, D.1
Bianco, C.2
Damiano, V.3
Bianco, R.4
Melisi, D.5
Mignogna, C.6
D'Armiento, F.P.7
Cionini, L.8
Bianco, A.R.9
Tortora, G.10
Ciardiello, F.11
Bunn, P.12
-
28
-
-
80054095608
-
Toll-like receptor 9 agonist IMO cooperates with cetuximab in K-ras mutant colorectal and pancreatic cancers
-
Rosa R, Melisi D, Damiano V, Bianco R, Garofalo S, Gelardi T, Agrawal S, Di Nicolantonio F, Scarpa A, Bardelli A and Tortora G. Toll-like receptor 9 agonist IMO cooperates with cetuximab in K-ras mutant colorectal and pancreatic cancers Clin Cancer Res. 2011; 17(20):6531-6541.
-
(2011)
Clin Cancer Res.
, vol.17
, Issue.20
, pp. 6531-6541
-
-
Rosa, R.1
Melisi, D.2
Damiano, V.3
Bianco, R.4
Garofalo, S.5
Gelardi, T.6
Agrawal, S.7
Di Nicolantonio, F.8
Scarpa, A.9
Bardelli, A.10
Tortora, G.11
|