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Volumn 6, Issue , 2015, Pages

Extreme multifunctional proteins identified from a human protein interaction network

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; MESSENGER RNA; PHOSPHOTRANSFERASE; PROTEIN; RIBONUCLEASE P; PROTEIN BINDING; PROTEOME;

EID: 84930966067     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8412     Document Type: Article
Times cited : (84)

References (57)
  • 1
    • 84875847924 scopus 로고    scopus 로고
    • Is junk dna bunk? A critique of encode
    • Doolittle, W. F. Is junk dna bunk? a critique of encode. Proc. Natl Acad. Sci. USA 110, 5294-5300 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 5294-5300
    • Doolittle, W.F.1
  • 2
    • 0035294473 scopus 로고    scopus 로고
    • Protein function from the perspective of molecular interactions and genetic networks
    • Jacq, B. Protein function from the perspective of molecular interactions and genetic networks. Brief. Bioinform. 2, 38-50 (2001).
    • (2001) Brief. Bioinform. , vol.2 , pp. 38-50
    • Jacq, B.1
  • 3
    • 84862324402 scopus 로고    scopus 로고
    • Moonlighting is mainstream: Paradigm adjustment required
    • Copley, S. D. Moonlighting is mainstream: paradigm adjustment required. Bioessays 34, 578-588 (2012).
    • (2012) Bioessays , vol.34 , pp. 578-588
    • Copley, S.D.1
  • 4
    • 0000110436 scopus 로고
    • Genetic control of biochemical reactions in neurospora: An 'aminobenzoicless' mutant
    • Tatum, E. L. & Beadle, G. W. Genetic control of biochemical reactions in neurospora: an 'aminobenzoicless' mutant. Proc. Natl Acad. Sci. USA 234-243 (1942).
    • (1942) Proc. Natl Acad. Sci. USA , pp. 234-243
    • Tatum, E.L.1    Beadle, G.W.2
  • 5
  • 6
    • 77954957537 scopus 로고    scopus 로고
    • The moonlighting function of pyruvate carboxylase resides in the noncatalytic end of the tim barrel
    • Huberts, D. H. E. W., Venselaar, H., Vriend, G., Veenhuis, M. & van der Klei, I. J. The moonlighting function of pyruvate carboxylase resides in the noncatalytic end of the tim barrel. Biochim. Biophys. Acta 1803, 1038-1042 (2010).
    • (2010) Biochim. Biophys. Acta , vol.1803 , pp. 1038-1042
    • Huberts, D.H.E.W.1    Venselaar, H.2    Vriend, G.3    Veenhuis, M.4    Van Der Klei, I.J.5
  • 7
    • 39149112760 scopus 로고    scopus 로고
    • The functional duality of iron regulatory protein 1
    • Volz, K. The functional duality of iron regulatory protein 1. Curr. Opin. Struct. Biol. 18, 106-111 (2008).
    • (2008) Curr. Opin. Struct. Biol. , vol.18 , pp. 106-111
    • Volz, K.1
  • 8
    • 43149106462 scopus 로고    scopus 로고
    • Cell-surface and mitotic-spindle rhamm: Moonlighting or dual oncogenic functions?
    • Maxwell, C. A., McCarthy, J. & Turley, E. Cell-surface and mitotic-spindle rhamm: moonlighting or dual oncogenic functions? J. Cell Sci. 121, 925-932 (2008).
    • (2008) J. Cell Sci. , vol.121 , pp. 925-932
    • Maxwell, C.A.1    McCarthy, J.2    Turley, E.3
  • 9
    • 77955894787 scopus 로고    scopus 로고
    • Multifunctional proteins bridge mitosis with motility and cancer with inflammation and arthritis
    • Jiang, J. et al. Multifunctional proteins bridge mitosis with motility and cancer with inflammation and arthritis. Sci. World J. 10, 1244-1257 (2010).
    • (2010) Sci. World J. , vol.10 , pp. 1244-1257
    • Jiang, J.1
  • 10
    • 0038634973 scopus 로고    scopus 로고
    • Do current sequence analysis algorithms disclose multifunctional (moonlighting) proteins?
    • Gómez, A., Domedel, N., Cedano, J., Piñol, J. & Querol, E. Do current sequence analysis algorithms disclose multifunctional (moonlighting) proteins? Bioinformatics 19, 895-896 (2003).
    • (2003) Bioinformatics , vol.19 , pp. 895-896
    • Gómez, A.1    Domedel, N.2    Cedano, J.3    Piñol, J.4    Querol, E.5
  • 11
    • 85018192920 scopus 로고    scopus 로고
    • Evaluation of function predictions by pfp, esg,and psi-blast for moonlighting proteins
    • Khan, I., Chitale, M., Rayon, C. & Kihara, D. Evaluation of function predictions by pfp, esg,and psi-blast for moonlighting proteins. BMC Proc. 6, S5 (2012).
    • (2012) BMC Proc. , vol.6 , pp. S5
    • Khan, I.1    Chitale, M.2    Rayon, C.3    Kihara, D.4
  • 12
    • 79959619604 scopus 로고    scopus 로고
    • Proteins with neomorphic moonlighting functions in disease
    • Jeffery, C. J. Proteins with neomorphic moonlighting functions in disease. IUBMB Life 63, 489-494 (2011).
    • (2011) IUBMB Life , vol.63 , pp. 489-494
    • Jeffery, C.J.1
  • 13
    • 84855178662 scopus 로고    scopus 로고
    • Multifunctional proteins revealed by overlapping clustering in protein interaction network
    • Becker, E., Robisson, B., Chapple, C. E., Guénoche, A. & Brun, C. Multifunctional proteins revealed by overlapping clustering in protein interaction network. Bioinformatics 28, 84-90 (2012).
    • (2012) Bioinformatics , vol.28 , pp. 84-90
    • Becker, E.1    Robisson, B.2    Chapple, C.E.3    Guénoche, A.4    Brun, C.5
  • 14
    • 0034069495 scopus 로고    scopus 로고
    • Gene ontology: Tool for the unification of biology. The gene ontology consortium
    • Ashburner, M. et al. Gene ontology: tool for the unification of biology. the gene ontology consortium. Nature Genet. 25, 25-29 (2000).
    • (2000) Nature Genet. , vol.25 , pp. 25-29
    • Ashburner, M.1
  • 15
    • 84877247688 scopus 로고    scopus 로고
    • Alternative splicing and protein interaction data sets
    • Talavera, D., Robertson, D. L. & Lovell, S. C. Alternative splicing and protein interaction data sets. Nature Biotechnol. 31, 292-293 (2013).
    • (2013) Nature Biotechnol. , vol.31 , pp. 292-293
    • Talavera, D.1    Robertson, D.L.2    Lovell, S.C.3
  • 17
    • 84876524220 scopus 로고    scopus 로고
    • D2P2: Database of disordered protein predictions
    • Oates, M. et al. D2P2: database of disordered protein predictions. Nucleic Acids Res. 41, D508-D516 (2013).
    • (2013) Nucleic Acids Res. , vol.41 , pp. D508-D516
    • Oates, M.1
  • 18
    • 84902446852 scopus 로고    scopus 로고
    • Short linear motifs: Ubiquitous and functionally diverse protein interaction modules directing cell regulation
    • Van Roey, K. et al. Short linear motifs: ubiquitous and functionally diverse protein interaction modules directing cell regulation. Chem. Rev. 114, 6733-6778 (2014).
    • (2014) Chem. Rev. , vol.114 , pp. 6733-6778
    • Van Roey, K.1
  • 19
    • 84876158670 scopus 로고    scopus 로고
    • The switches.elm resource: A compendium of conditional regulatory interaction interfaces
    • Van Roey, K., Dinkel, H., Weatheritt, R. J., Gibson, T. J. & Davey, N. E. The switches.elm resource: a compendium of conditional regulatory interaction interfaces. Sci. Signal. 6, rs7 (2013).
    • (2013) Sci. Signal. , vol.6 , pp. rs7
    • Van Roey, K.1    Dinkel, H.2    Weatheritt, R.J.3    Gibson, T.J.4    Davey, N.E.5
  • 21
    • 1542515338 scopus 로고    scopus 로고
    • A census of human cancer genes
    • Futreal, P. A. et al. A census of human cancer genes. Nat. Rev. Cancer 4, 177-183 (2004).
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 177-183
    • Futreal, P.A.1
  • 22
    • 84911474471 scopus 로고    scopus 로고
    • A proteome-scale map of the human interactome network
    • Rolland, T. et al. A proteome-scale map of the human interactome network. Cell 159, 1212-1226 (2014).
    • (2014) Cell , vol.159 , pp. 1212-1226
    • Rolland, T.1
  • 23
    • 78649863822 scopus 로고    scopus 로고
    • Erbb2 receptor controls microtubule capture by recruiting acf7 to the plasma membrane of migrating cells
    • Zaoui, K., Benseddik, K., Daou, P., Salaün, D. & Badache, A. Erbb2 receptor controls microtubule capture by recruiting acf7 to the plasma membrane of migrating cells. Proc. Natl Acad. Sci. USA 107, 18517-18522 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 18517-18522
    • Zaoui, K.1    Benseddik, K.2    Daou, P.3    Salaün, D.4    Badache, A.5
  • 24
    • 79958789805 scopus 로고    scopus 로고
    • Nuclear erbb2 enhances translation and cell growth by activating transcription of ribosomal rna genes
    • Li, L.-Y. et al. Nuclear erbb2 enhances translation and cell growth by activating transcription of ribosomal rna genes. Cancer Res. 71, 4269-4279 (2011).
    • (2011) Cancer Res. , vol.71 , pp. 4269-4279
    • Li, L.-Y.1
  • 25
    • 54549088876 scopus 로고    scopus 로고
    • Rnase p without rna: Identification and functional reconstitution of the human mitochondrial trna processing enzyme
    • Holzmann, J. et al. Rnase p without rna: identification and functional reconstitution of the human mitochondrial trna processing enzyme. Cell 135, 462-474 (2008).
    • (2008) Cell , vol.135 , pp. 462-474
    • Holzmann, J.1
  • 26
    • 78049290801 scopus 로고    scopus 로고
    • Modularity in the hippo signaling pathway
    • Sudol, M. & Harvey, K. F. Modularity in the hippo signaling pathway. Trends Biochem. Sci. 35, 627-633 (2010).
    • (2010) Trends Biochem. Sci. , vol.35 , pp. 627-633
    • Sudol, M.1    Harvey, K.F.2
  • 27
    • 1542268960 scopus 로고    scopus 로고
    • The membrane-associated form of the dna repair protein ku is involved in cell adhesion to fibronectin
    • Monferran, S., Muller, C., Mourey, L., Frit, P. & Salles, B. The membrane-associated form of the dna repair protein ku is involved in cell adhesion to fibronectin. J. Mol. Biol. 337, 503-511 (2004).
    • (2004) J. Mol. Biol. , vol.337 , pp. 503-511
    • Monferran, S.1    Muller, C.2    Mourey, L.3    Frit, P.4    Salles, B.5
  • 29
    • 1442329655 scopus 로고    scopus 로고
    • Functional classification of proteins for the prediction of cellular function from a protein-protein interaction network
    • Brun, C. et al. Functional classification of proteins for the prediction of cellular function from a protein-protein interaction network. Genome Biol. 5, R6 (2003).
    • (2003) Genome Biol. , vol.5 , pp. R6
    • Brun, C.1
  • 30
    • 33947252154 scopus 로고    scopus 로고
    • Network-based prediction of protein function
    • Sharan, R., Ulitsky, I. & Shamir, R. Network-based prediction of protein function. Mol. Syst. Biol. 3, 88 (2007).
    • (2007) Mol. Syst. Biol. , vol.3 , pp. 88
    • Sharan, R.1    Ulitsky, I.2    Shamir, R.3
  • 31
    • 79960376932 scopus 로고    scopus 로고
    • Do protein-protein interaction databases identify moonlighting proteins?
    • Gómez, A. et al. Do protein-protein interaction databases identify moonlighting proteins? Mol. Biosyst. 7, 2379-2382 (2011).
    • (2011) Mol. Biosyst. , vol.7 , pp. 2379-2382
    • Gómez, A.1
  • 32
    • 23944514504 scopus 로고    scopus 로고
    • Structural disorder throws new light on moonlighting
    • Tompa, P., Szàsz, C. & Buday, L. Structural disorder throws new light on moonlighting. Trends Biochem. Sci. 30, 484-489 (2005).
    • (2005) Trends Biochem. Sci. , vol.30 , pp. 484-489
    • Tompa, P.1    Szàsz, C.2    Buday, L.3
  • 33
    • 27144464910 scopus 로고    scopus 로고
    • Flexible nets. The roles of intrinsic disorder in protein interaction networks
    • Dunker, A. K., Cortese, M. S., Romero, P., Iakoucheva, L. M. & Uversky, V. N. Flexible nets. the roles of intrinsic disorder in protein interaction networks. FEBS J. 272, 5129-5148 (2005).
    • (2005) FEBS J. , vol.272 , pp. 5129-5148
    • Dunker, A.K.1    Cortese, M.S.2    Romero, P.3    Iakoucheva, L.M.4    Uversky, V.N.5
  • 34
    • 77955121836 scopus 로고    scopus 로고
    • Domain distribution and intrinsic disorder in hubs in the human protein-protein interaction network
    • Patil, A., Kinoshita, K. & Nakamura, H. Domain distribution and intrinsic disorder in hubs in the human protein-protein interaction network. Protein Sci. 19, 1461-1468 (2010).
    • (2010) Protein Sci. , vol.19 , pp. 1461-1468
    • Patil, A.1    Kinoshita, K.2    Nakamura, H.3
  • 35
    • 84870696425 scopus 로고    scopus 로고
    • Do moonlighting proteins belong to the intrinsically disordered protein class?
    • Hernández, S. et al. Do moonlighting proteins belong to the intrinsically disordered protein class? Proteomics Bioinformatics 5, 262-264 (2012).
    • (2012) Proteomics Bioinformatics , vol.5 , pp. 262-264
    • Hernández, S.1
  • 36
    • 82655175482 scopus 로고    scopus 로고
    • Attributes of short linear motifs
    • Davey, N. E. et al. Attributes of short linear motifs. Mol. Biosyst. 8, 268-281 (2012).
    • (2012) Mol. Biosyst. , vol.8 , pp. 268-281
    • Davey, N.E.1
  • 37
    • 34249695447 scopus 로고    scopus 로고
    • Local structural disorder imparts plasticity on linear motifs
    • Fuxreiter, M., Tompa, P. & Simon, I. Local structural disorder imparts plasticity on linear motifs. Bioinformatics 23, 950-956 (2007).
    • (2007) Bioinformatics , vol.23 , pp. 950-956
    • Fuxreiter, M.1    Tompa, P.2    Simon, I.3
  • 38
    • 79959846617 scopus 로고    scopus 로고
    • Psicquic and psiscore: Accessing and scoring molecular interactions
    • Aranda, B. et al. Psicquic and psiscore: accessing and scoring molecular interactions. Nat. Methods 8, 528-529 (2011).
    • (2011) Nat. Methods , vol.8 , pp. 528-529
    • Aranda, B.1
  • 39
    • 33747853260 scopus 로고    scopus 로고
    • Apid: Agile protein interaction dataanalyzer
    • Prieto, C. & Rivas, J. D. L. Apid: Agile protein interaction dataanalyzer. Nucleic Acids Res. 34, W298-W302 (2006).
    • (2006) Nucleic Acids Res. , vol.34 , pp. W298-W302
    • Prieto, C.1    Rivas, J.D.L.2
  • 40
    • 84874947727 scopus 로고    scopus 로고
    • The biogrid interaction database: 2013 Update
    • Chatr-Aryamontri, A. et al. The biogrid interaction database: 2013 update. Nucleic Acids Res. 41, D816-D823 (2013).
    • (2013) Nucleic Acids Res. , vol.41 , pp. D816-D823
    • Chatr-Aryamontri, A.1
  • 41
    • 84859204939 scopus 로고    scopus 로고
    • The intact molecular interaction database in 2012
    • Kerrien, S. et al. The intact molecular interaction database in 2012. Nucleic Acids Res. 40, D841-D846 (2012).
    • (2012) Nucleic Acids Res. , vol.40 , pp. D841-D846
    • Kerrien, S.1
  • 42
    • 0347755535 scopus 로고    scopus 로고
    • The database of interacting proteins: 2004 Update
    • Salwinski, L. et al. The database of interacting proteins: 2004 update. Nucleic Acids Res. 32, D449-D451 (2004).
    • (2004) Nucleic Acids Res. , vol.32 , pp. D449-D451
    • Salwinski, L.1
  • 43
    • 75549083295 scopus 로고    scopus 로고
    • Mint, the molecular interaction database: 2009 Update
    • Ceol, A. et al. Mint, the molecular interaction database: 2009 update. Nucleic Acids Res. 38, D532-D539 (2010).
    • (2010) Nucleic Acids Res. , vol.38 , pp. D532-D539
    • Ceol, A.1
  • 44
    • 61449243886 scopus 로고    scopus 로고
    • Matrixdb, a database focused on extracellular protein-protein and protein-carbohydrate interactions
    • Chautard, E., Ballut, L., Thierry-Mieg, N. & Ricard-Blum, S. Matrixdb, a database focused on extracellular protein-protein and protein-carbohydrate interactions. Bioinformatics 25, 690-691 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 690-691
    • Chautard, E.1    Ballut, L.2    Thierry-Mieg, N.3    Ricard-Blum, S.4
  • 45
    • 78651275182 scopus 로고    scopus 로고
    • Reactome: A database of reactions, pathways and biological processes
    • Croft, D. et al. Reactome: a database of reactions, pathways and biological processes. Nucleic Acids Res. 39, D691-D697 (2011).
    • (2011) Nucleic Acids Res. , vol.39 , pp. D691-D697
    • Croft, D.1
  • 46
    • 51049113607 scopus 로고    scopus 로고
    • Innatedb: Facilitating systems-level analyses of the mammalian innate immune response
    • Lynn, D. J. et al. Innatedb: facilitating systems-level analyses of the mammalian innate immune response. Mol. Syst. Biol. 4, 218 (2008).
    • (2008) Mol. Syst. Biol. , vol.4 , pp. 218
    • Lynn, D.J.1
  • 47
    • 40549138085 scopus 로고    scopus 로고
    • Spike-a database, visualization and analysis tool of cellular signaling pathways
    • Elkon, R. et al. Spike-a database, visualization and analysis tool of cellular signaling pathways. BMC Bioinformatics 9, 110 (2008).
    • (2008) BMC Bioinformatics , vol.9 , pp. 110
    • Elkon, R.1
  • 48
    • 80052290625 scopus 로고    scopus 로고
    • Topfind, a knowledgebase linking protein termini with function
    • Lange, P. F. & Overall, C. M. Topfind, a knowledgebase linking protein termini with function. Nat. Methods 8, 703-704 (2011).
    • (2011) Nat. Methods , vol.8 , pp. 703-704
    • Lange, P.F.1    Overall, C.M.2
  • 49
    • 84870431038 scopus 로고    scopus 로고
    • Cd-hit: Accelerated for clustering the next-generation sequencing data
    • Fu, L., Niu, B., Zhu, Z., Wu, S. & Li, W. Cd-hit: accelerated for clustering the next-generation sequencing data. Bioinformatics 28, 3150-3152 (2012).
    • (2012) Bioinformatics , vol.28 , pp. 3150-3152
    • Fu, L.1    Niu, B.2    Zhu, Z.3    Wu, S.4    Li, W.5
  • 50
    • 84863693531 scopus 로고    scopus 로고
    • Quality of computationally inferred gene ontology annotations
    • Skunca, N., Altenhoff, A. & Dessimoz, C. Quality of computationally inferred gene ontology annotations. PLoS Comp. 8, e1002533 (2012).
    • (2012) PLoS Comp. , vol.8
    • Skunca, N.1    Altenhoff, A.2    Dessimoz, C.3
  • 51
    • 43349094507 scopus 로고    scopus 로고
    • The igraph software package for complex network research
    • Csardi, G. & Nepusz, T. The igraph software package for complex network research. InterJournal, Complex Systems, 1695 (2006).
    • (2006) InterJournal, Complex Systems , pp. 1695
    • Csardi, G.1    Nepusz, T.2
  • 52
    • 35348873256 scopus 로고    scopus 로고
    • Predicting active site residue annotations in the pfam database
    • Mistry, J., Bateman, A. & Finn, R. D. Predicting active site residue annotations in the pfam database. BMC Bioinformatics 8, 298-312 (2007).
    • (2007) BMC Bioinformatics , vol.8 , pp. 298-312
    • Mistry, J.1    Bateman, A.2    Finn, R.D.3
  • 53
    • 11144358198 scopus 로고    scopus 로고
    • A gene atlas of the mouse and human protein-encoding transcriptomes
    • Su, A. I. et al. A gene atlas of the mouse and human protein-encoding transcriptomes. Proc. Natl Acad. Sci. USA 101, 6062-6067 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 6062-6067
    • Su, A.I.1
  • 54
    • 52649145895 scopus 로고    scopus 로고
    • Gps 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy
    • Xue, Y. et al. Gps 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy. Mol. Cell Proteomics 7, 1598-1608 (2008).
    • (2008) Mol. Cell Proteomics , vol.7 , pp. 1598-1608
    • Xue, Y.1
  • 55
    • 0034623005 scopus 로고    scopus 로고
    • T-coffee: A novel method for fast and accurate multiple sequence alignment
    • Notredame, C., Higgins, D. G. & Heringa, J. T-coffee: a novel method for fast and accurate multiple sequence alignment. J. Mol. Biol. 302, 205-217 (2000).
    • (2000) J. Mol. Biol. , vol.302 , pp. 205-217
    • Notredame, C.1    Higgins, D.G.2    Heringa, J.3
  • 56
    • 84891768365 scopus 로고    scopus 로고
    • Ensembl 2014
    • Flicek, P. et al. Ensembl 2014. Nucleic Acids Res. 42, D749-D755 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. D749-D755
    • Flicek, P.1
  • 57
    • 0042622252 scopus 로고    scopus 로고
    • Elm server: A new resource for investigating short functional sites in modular eukaryotic proteins
    • Puntervoll, P. et al. Elm server: a new resource for investigating short functional sites in modular eukaryotic proteins. Nucleic Acids Res. 31, 3625-3630 (2003).
    • (2003) Nucleic Acids Res. , vol.31 , pp. 3625-3630
    • Puntervoll, P.1


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