Gene delivery into plant cells for recombinant protein production

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Chen, Qiang ^a,b   Lai, Huafang ^a  

^a Arizona State University   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT PROTEIN; VIRUS VECTOR;

AGROBACTERIUM; AGROINFILTRATION; BIOTECHNOLOGICAL PROCEDURES; CLINICAL TRIAL (TOPIC); COWPEA MOSAIC VIRUS; GENE TARGETING; HUMAN; LUTEOVIRUS; NICOTIANA; NICOTIANA BENTHAMIANA; NONHUMAN; PHASE 1 CLINICAL TRIAL (TOPIC); PLANT CELL; REVIEW; TOBACCO MOSAIC VIRUS; TRANSGENIC ORGANISM; TRANSIENT EXPRESSION; WEST NILE VIRUS; BIOSYNTHESIS; GENE EXPRESSION; GENE TRANSFER; GENETICS; METABOLISM;

HEXAPODA; MAMMALIA; NICOTIANA;

GENE EXPRESSION; GENE TRANSFER TECHNIQUES; HUMANS; PLANT CELLS; RECOMBINANT PROTEINS;

EID: 84930960310     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/932161     Document Type: Review

References (59)

1. Y. Y. Gleba, D. Tuse, and A. Giritch, "Plant viral vectors for delivery by Agrobacterium, " in Plant Viral Vectors, K. Palmer and Y. Gleba, Eds., vol. 375 of Current Topics in Microbiology and Immunology, pp. 155-192, Springer, Berlin, Germany, 2014.
2. M.-A. DAoust, M. M.-J. Couture, N. Charland, et al., "The production of hemagglutinin-based virus-like particles in plants: a rapid, efficient and safe response to pand emic influenza, " Plant Biotechnology Journal, vol. 8, no. 5, pp. 607-619, 2010.
3. H. M. Davies, "Commercialization of whole-plant systems for biomanufacturing of protein products: evolution and prospects, " Plant Biotechnology Journal, vol. 8, no. 8, pp. 845-861, 2010.
4. T. V. Komarova, S. Baschieri, M. Donini, C. Marusic, E. Benvenuto, and Y. L. Dorokhov, "Transient expression systems for plant-derived biopharmaceuticals, " Expert Review of Vaccines, vol. 9, no. 8, pp. 859-876, 2010.
5. A. L. Rivera, M. Gomez-Lim, F. Fernand ez, and A. M. Loske, "Physical methods for genetic plant transformation, " Physics of Life Reviews, vol. 9, no. 3, pp. 308-345, 2012.
6. J. C. Sanford, "Biolistic plant transformation, " Physiologia Plantarum, vol. 79, no. 1, pp. 206-209, 1990.
7. H. Klee, R. Horsch, and S. Rogers, "Agrobacterium-mediated plant transformation and its further applications to plant biology, " Annual Review of Plant Physiology, vol. 38, pp. 467-486, 1987.
8. Z. Vaghchhipawala, C. M. Rojas, M. Senthil-Kumar, and K. S. Mysore, "Agroinoculation and agroinfiltration: simple tools for complex gene function analyses, "Methods inMolecular Biology, vol. 678, pp. 65-76, 2011.
9. Q. Chen, "Expression and manufacture of pharmaceutical proteins in genetically engineered horticultural plants, " in Transgenic Horticultural Crops: Challenges and Opportunities-Essays by Experts, B. Mouand R. Scorza, Eds., pp. 83-124, Taylor & Francis, Boca Raton, Fla, USA, 2011.
10. N. Grimsley, B. Hohn, T. Hohn, and R. Walden, "Agroinfection an alternative route for viral infection of plants by using the Ti plasmid, " Proceedings of the National Academy of Sciences of the United States of America, vol. 83, no. 10, pp. 3282-3286, 1986.
11. T. Wroblewski, A. Tomczak, and R. Michelmore, "Optimization of Agrobacterium-mediated transient assays of gene expression in lettuce, tomato and Arabidopsis, " Plant Biotechnology Journal, vol. 3, no. 2, pp. 259-273, 2005.
12. Q. Chen, M. Dent, J. Hurtado, et al., "Transient protein expression by agroinfiltration in lettuce, " in Recombinant Proteins from Plants, R. Menassa, J. Macdonald, and I. Kolotilin, Eds., 2014.
13. N. Takata and M. E. Eriksson, "A simple and efficient transient transformation for hybrid aspen (Populus tremula × P. tremuloides), " Plant Methods, vol. 8, no. 1, article 30, 2012.
14. X. Chen, R. Equi, H. Baxter, et al., "A high-throughput transient gene expression system for switchgrass (Panicum virgatum L. ) seedlings, " Biotechnology for Biofuels, vol. 3, article 9, 2010.
15. K. Leuzinger, M. Dent, J. Hurtado, et al., "Efficient agroinfiltration of plants for high-level transient expression of recombinant proteins, " Journal of Visualized Experiments, no. 77, Article ID e50521, 2013.
16. H. Lai and Q. Chen, "Bioprocessing of plant-derived virus-like particles of Norwalk virus capsid protein under current Good Manufacture Practice regulations, " PlantCell Reports, vol. 31, no. 3, pp. 573-584, 2012.
17. H. Lai, M. Engle, A. Fuchs, et al., "Monoclonal antibody produced in plants efficiently treats West Nile virus infection in mice, " Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 6, pp. 2419-2424, 2010.
18. J. He, H. Lai, C. Brock, and Q. Chen, "A novel system for rapid and cost-effective production of detection and diagnostic reagents ofWestNile virus in plants, " Journal of Biomedicine and Biotechnology, vol. 2012, Article ID 106783, 10 pages, 2012.
19. Z. Huang, Q. Chen, B. Hjelm, C. Arntzen, and H. Mason, "A DNA replicon system for rapid high-level production of viruslike particles in plants, " Biotechnology and Bioengineering, vol. 103, no. 4, pp. 706-714, 2009.
20. Q. Chen and H. Lai, "Plant-derived virus-like particles as vaccines, " Human Vaccines and Immunotherapeutics, vol. 9, no. 1, pp. 26-49, 2013.
21. Q. Chen, "Virus-like particle vaccines for norovirus gastroenteritis, " in Molecular Vaccines, M. Giese, Ed., pp. 153-181, Springer, Vienna, Austria, 2013.
22. G. P. Pogue, F. Vojdani, K. E. Palmer, et al., "Production of pharmaceutical-grade recombinant aprotinin and a monoclonal antibody product using plant-based transient expression systems, " Plant Biotechnology Journal, vol. 8, no. 5, pp. 638-654, 2010.
23. P. Roemer, L. Bortesi, D. Tiede, A. Giritch, and Y. Gleba, "Agrobacterium for transient transfection of whole plants, " Patent applicationWO2013149726 A1, E. P. Office, Ed, 2013.
24. M. C. Canizares, L. Nicholson, and G. P. Lomonossoff, "Use of viral vectors for vaccine production in plants, " Immunology and Cell Biology, vol. 83, no. 3, pp. 263-270, 2005.
25. C. Lico, Q. Chen, and L. Santi, "Viral vectors for production of recombinant proteins in plants, " Journal of Cellular Physiology, vol. 216, no. 2, pp. 366-377, 2008.
26. A. Giritch, S. Marillonnet, C. Engler, et al., "Rapid high-yield expression of full-size IgG antibodies in plants coinfected with noncompeting viral vectors, " Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 40, pp. 14701-14706, 2006.
27. W. Phoolcharoen, S. H. Bhoo, H. Lai, et al., "Expression of an immunogenic Ebola immune complex in Nicotiana benthamiana, " Plant Biotechnology Journal, vol. 9, no. 7, pp. 807-816, 2011.
28. H. Lai, J. He, J. Hurtado, et al., "Structural and functional characterization of an anti-West Nile virus monoclonal antibody and its single-chain variant produced in glycoengineered plants, " Plant Biotechnology Journal, vol. 12, no. 8, pp. 1098-1107, 2014.
29. M. Bendand i, S. Marillonnet, R. Kand zia, et al., "Rapid, highyield production in plants of individualized idiotype vaccines for non-Hodgkins lymphoma, " Annals of Oncology, vol. 21, no. 12, pp. 2420-2427, 2010.
30. E. C. Thuenemann, A. E. Meyers, J. Verwey, E. P. Rybicki, and G. P. Lomonossoff, "A method for rapid production of heteromultimeric protein complexes in plants: assembly of protective bluetongue virus-like particles, " Plant Biotechnology Journal, vol. 11, no. 7, pp. 839-846, 2013.
31. Q. Chen, J. He, W. Phoolcharoen, and H. S. Mason, "Geminiviral vectors based on bean yellow dwarf virus for production of vaccine antigens and monoclonal antibodies in plants, " Human Vaccines, vol. 7, no. 3, pp. 331-338, 2011.
32. Z. Huang, W. Phoolcharoen, H. Lai, et al., "High-level rapid production of full-sizemonoclonal antibodies in plants by a singlevectorDNAreplicon system, " Biotechnology and Bioengineering, vol. 106, no. 1, pp. 9-17, 2010.
33. G. L. Regnard, R. P. Halley-Stott, F. L. Tanzer, I. I. Hitzeroth, and E. P. Rybicki, "High level protein expression in plants through the use of a novel autonomously replicating geminivirus shuttle vector, " Plant Biotechnology Journal, vol. 8, no. 1, pp. 38-46, 2010.
34. H. Lai, J. He, M. Engle, M. S. Diamond, and Q. Chen, "Robust production of virus-like particles and monoclonal antibodies with geminiviral replicon vectors in lettuce, " Plant Biotechnology Journal, vol. 10, no. 1, pp. 95-104, 2012.
35. F. Sainsbury, M. Sack, J. Stadlmann, H. Quendler, R. Fischer, and G. P. Lomonossoff, "Rapid transient production in plants by replicating and non-replicating vectors yields high quality functional anti-HIV antibody, " PLoS ONE, vol. 5, no. 11, Article ID e13976, 2010.
36. B. Dugdale, C. L. Mortimer, M. Kato, T. A. James, R. M. Harding, and J. L. Dale, "In plant activation: an inducible, hyperexpression platform for recombinant protein production in plants, " The Plant Cell, vol. 25, no. 7, pp. 2429-2443, 2013.
37. A. A. McCormick, S. Reddy, S. J. Reinl, et al., "Plant-produced idiotype vaccines for the treatment of non-Hodgkins lymphoma: safety and immunogenicity in a phase I clinical study, " Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 29, pp. 10131-10136, 2008.
38. C. Potera, "Vaccine manufacturing gets boost from tobacco plants: Canada-basedmedicago opens U. S. Facility to exploit its influenza vaccine production method, " Genetic Engineering and Biotechnology News, vol. 32, no. 6, pp. 8-10, 2012.
39. Medicago, "Clinical trials update: avian flu vaccine, " Genetic Engineering & Biotechnology News, vol. 31, no. 14, p. 61, 2011.
40. IconGenetics Icon Genetics successfully completes Phase I clinical study with personalized vaccines for treatment of non-Hodgkins lymphoma, 2014 http://www.icongenetics.com/html/5975.htm.
41. J. He, H. Lai, M. Engle, et al., "Generation and analysis of novel plant-derived antibody-based therapeutic molecules against WestNile virus, " PLoSONE, vol. 9, no. 3, Article IDe93541, 2014.
42. S. Hahn, A. Giritch, and Y. Gleba, "Production, storage and use of cell wall-degrading enzymes, " Patent Application, E. P. Office Ed., 2013.
43. W. Phoolcharoen, J. M. Dye, J. Kilbourne, et al., "A nonreplicating subunit vaccine protects mice against lethal Ebola virus challenge, " Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 51, pp. 20695-20700, 2011.
44. F. Sainsbury and G. P. Lomonossoff, "Extremely high-level and rapid transient protein production in plants without the use of viral replication, " Plant Physiology, vol. 148, no. 3, pp. 1212-1218, 2008.
45. G. G. Olinger Jr., J. Pettitt, D. Kim, et al., "Delayed treatment of Ebola virus infection with plant-derivedmonoclonal antibodies provides protection in rhesus macaques, " Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 44, pp. 18030-18035, 2012.
46. L. Santi, L. Batchelor, Z. Huang, et al., "An efficient plant viral expression system generating orally immunogenic Norwalk virus-like particles, " Vaccine, vol. 26, no. 15, pp. 1846-1854, 2008.
47. J. He, L. Peng, H. Lai, J. Hurtado, J. Stahnke, and Q. Chen, "A plant-produced antigen elicits potent immune responses against west nile virus in mice, " BioMed Research International, vol. 2014, Article ID952865, 10 pages, 2014.
48. D. Klein-Marcuschamer, P. Oleskowicz-Popiel, B. A. Simmons, and H. W. Blanch, "The challenge of enzyme cost in the production of lignocellulosic biofuels, " Biotechnology and Bioengineering, vol. 109, no. 4, pp. 1083-1087, 2012.
49. D. Tuse, T. Tu, and K. McDonald, "Manufacturing economics of plant-made biologics: case studies in therapeutic and industrial enzymes, " BioMed Research International, vol. 2014, Article ID 256135, 16 pages, 2014.
50. Q. Chen and H. Lai, "Plant-derived monoclonal antibodies as human biologics for infectious disease and cancer, " in Plant-derived Pharmaceuticals: Principles and Applications for Developing Countries, K. L. Hefferon, Ed., pp. 42-75, CABI, Cryodon, UK, 2014.
51. R. Strasser, J. Stadlmann, M. Schahs, et al., "Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like Nglycan structure, " Plant Biotechnology Journal, vol. 6, no. 4, pp. 392-402, 2008.
52. L. Zeitlin, J. Pettitt, C. Scully, et al., "Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant, " Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 51, pp. 20690-20694, 2011.
53. E. C. Hayden and S. Reardon, "Should experimental drugs be used in the Ebola outbreak?" Nature, 2014.
54. R. A. L. Van Der Hoorn, F. Laurent, R. Roth, and P. J. G. M. De Wit, "Agroinfiltration is a versatile tool that facilitates comparative analyses of Avr9/Cf-9-induced and Avr4/Cf-4-induced necrosis, "Molecular Plant-Microbe Interactions, vol. 13, no. 4, pp. 439-446, 2000.
55. A. C. A. Roque, C. R. Lowe, and M. A. Taipa, "Antibodies and genetically engineered related molecules: production and purification, " Biotechnology Progress, vol. 20, no. 3, pp. 639-654, 2004.
56. C. Hey and C. Zhang, "Process development for antibody purification fromtobacco by protein a affinity chromatography, " Chemical Engineering and Technology, vol. 35, no. 1, pp. 142-148, 2012.
57. V. Negrouk, G. Eisner, H.-I. Lee, K. Han, D. Taylor, and H. C. Wong, "Highly efficient transient expression of functional recombinant antibodies in lettuce, " Plant Science, vol. 169, no. 2, pp. 433-438, 2005.
58. J. Li, M. Chen, X.-W. Liu, H.-C. Zhang, F. F. Shen, and G. P. Wang, "Transient expression of an active human interferonbeta in lettuce, " Scientia Horticulturae, vol. 112, no. 3, pp. 258-265, 2007.
59. Q. Chen, "Expression and purification of pharmaceutical proteins in plants, " Biological Engineering, vol. 1, no. 4, pp. 291-321, 2008.