Rapid transient production in plants by replicating and non-replicating vectors yields high quality functional anti-HIV antibody

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Sainsbury, Frank ^a,f   Sack, Markus ^b   Stadlmann, Johannes ^c   Quendler, Heribert ^d,g   Fischer, Rainer ^b,e   Lomonossoff, George P ^a  

^a JOHN INNES CENTRE   (United Kingdom)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^d UNIVERSITY OF AGRICULTURAL SCIENCES   (Austria)

^e FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

^f UNIVERSITÉ LAVAL   (Canada)

^g SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCAN; MONOCLONAL ANTIBODY 2G12; VIRUS VECTOR; MONOCLONAL ANTIBODY; POLYSACCHARIDE; RECOMBINANT PROTEIN;

ANTIBODY AFFINITY; ANTIBODY PRODUCTION; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; COWPEA; ENDOPLASMIC RETICULUM; EXPRESSION VECTOR; GENE DELETION; GLYCOSYLATION; MOSAIC VIRUS; NONHUMAN; PLANT; PLANT LEAF; PLANT TISSUE; PROTEIN EXPRESSION; QUALITY CONTROL; VIRUS NEUTRALIZATION; VIRUS PURIFICATION; VIRUS REPLICATION; ANIMAL; CHO CELL; CRICETULUS; GENE VECTOR; GENETICS; HAMSTER; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNOLOGY; METABOLISM; SURFACE PLASMON RESONANCE; TOBACCO; WESTERN BLOTTING;

COWPEA MOSAIC VIRUS; CRICETULUS GRISEUS;

ANIMALS; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; CHO CELLS; COMOVIRUS; CRICETINAE; CRICETULUS; GENETIC VECTORS; GLYCOSYLATION; HIV; HUMANS; POLYSACCHARIDES; RECOMBINANT PROTEINS; SURFACE PLASMON RESONANCE; TOBACCO; VIRUS REPLICATION;

EID: 78649720518     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013976     Document Type: Article

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