Selective activation of the trace amine-associated receptor 1 decreases cocaine's reinforcing efficacy and prevents cocaine-induced changes in brain reward thresholds

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 63, Issue , 2015, Pages 70-75

  Pei, Yue ^a,b   Mortas, Patrick ^c   Hoener, Marius C ^c   Canales, Juan J ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF CANTERBURY   (New Zealand)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Cocaine; Intracranial self stimulation; Reward; Self administration; Trace amine associated receptor 1

Indexed keywords

COCAINE; RECEPTOR; TRACE AMINE ASSOCIATED RECEPTOR 1; UNCLASSIFIED DRUG; 4-(3,4-DICHLOROPHENYL)-4,5-DIHYDROOXAZOL-2-YLAMINE; 4-(3-FLUORO-2-METHYLPHENYL)-4,5-DIHYDROOXAZOL-2-YLAMINE; DOPAMINE UPTAKE INHIBITOR; G PROTEIN COUPLED RECEPTOR; OXAZOLE DERIVATIVE; TRACE AMINE-ASSOCIATED RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COCAINE DEPENDENCE; CONTROLLED STUDY; ELECTROSTIMULATION; MALE; NONHUMAN; RAT; REINFORCEMENT; REWARD; SELF STIMULATION; STIMULUS RESPONSE; VENTRAL TEGMENTUM; AGONISTS; ANALYSIS OF VARIANCE; ANIMAL; BRAIN; DOSE RESPONSE; DRUG EFFECTS; DRUG SELF ADMINISTRATION; INSTRUMENTAL CONDITIONING; LONG EVANS RAT; METABOLISM;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN; COCAINE; CONDITIONING, OPERANT; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; OXAZOLES; RATS; RATS, LONG-EVANS; RECEPTORS, G-PROTEIN-COUPLED; REWARD; SELF ADMINISTRATION; VENTRAL TEGMENTAL AREA;

EID: 84930958408     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2015.05.014     Document Type: Article

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