Multiplexed tracking of combinatorial genomic mutations in engineered cell populations

Nature Biotechnology

Volumn 33, Issue 6, 2015, Pages 631-637

  Zeitoun, Ramsey I ^a   Garst, Andrew D ^a   Degen, George D ^b   Pines, Gur ^a   Mansell, Thomas J ^a   Glebes, Tirzah Y ^a   Boyle, Nanette R ^c   Gill, Ryan T ^a  

^a University of Colorado at Boulder   (United States)

^b CARNEGIE MELLON UNIVERSITY   (United States)

^c Department of Metallurgical and Materials Engineering   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL PROLIFERATION; CELLS; CYTOLOGY; ESCHERICHIA COLI; GENE ENCODING; GENES; LIBRARIES; MULTIPLEXING;

COMBINATORIAL ENGINEERING; COMBINATORIAL LIBRARY; GENETIC DIVERSITY; GENOME ENGINEERING; GROWTH SELECTION; NEXT-GENERATION SEQUENCING; OVARIAN CARCINOMA CELL; SINGLE CELL RESOLUTION;

CELL ENGINEERING;

DNA;

ARTICLE; BACTERIAL GROWTH; BACTERIUM MUTANT; CARCINOMA CELL LINE; CELL ENGINEERING; CELL POPULATION; COMBINATORIAL CHEMISTRY; COMBINATORIAL LIBRARY; CONTROLLED STUDY; ESCHERICHIA COLI; GENE MAPPING; GENE MUTATION; GENOTYPE PHENOTYPE CORRELATION; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; NEXT GENERATION SEQUENCING; NONHUMAN; OVARY CARCINOMA; PRIORITY JOURNAL; BACTERIAL GENOME; GENETIC ASSOCIATION; GENETIC ENGINEERING; GENETIC VARIABILITY; GENETICS; GENOMICS; MUTATION; SINGLE CELL ANALYSIS;

ESCHERICHIA COLI; EUKARYOTA;

ESCHERICHIA COLI; GENETIC ASSOCIATION STUDIES; GENETIC ENGINEERING; GENETIC VARIATION; GENOME, BACTERIAL; GENOMICS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MUTATION; SINGLE-CELL ANALYSIS;

EID: 84930936429     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.3177     Document Type: Article

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