The histone demethylase PHF8 represses cardiac hypertrophy upon pressure overload

Experimental Cell Research

Volumn 335, Issue 1, 2015, Pages 123-134

  Liu, Xiaoqian ^a,b   Wang, Xuping ^a   Bi, Yanping ^b   Bu, Peili ^a   Zhang, Mingxiang ^a  

^a SHANDONG UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF SHANDONG FIRST MEDICAL UNIVERSITY   (China)

Author keywords

Cardiac hypertrophy; Fibrosis; MTOR; PHF8; Rapamycin

Indexed keywords

HISTONE DEMETHYLASE; HISTONE DEMETHYLASE PHF8; MESSENGER RNA; RAPAMYCIN; UNCLASSIFIED DRUG; MTOR PROTEIN, MOUSE; PHF8 PROTEIN, HUMAN; PROTEIN KINASE B; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ECHOCARDIOGRAPHY; GENE EXPRESSION; GENE OVEREXPRESSION; HEART FUNCTION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE OVERLOAD; HUMAN; HUMAN CELL; HYPERTROPHIC CARDIOMYOPATHY; IN VIVO STUDY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; TRANSGENIC MOUSE; UPREGULATION; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CARDIOMEGALY; CELL CULTURE; ENZYMOLOGY; GENETICS; HYPERTENSION; MALE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

MAMMALIA; MUS MUSCULUS; RATTUS;

ANIMALS; CARDIOMEGALY; CELLS, CULTURED; DOWN-REGULATION; HISTONE DEMETHYLASES; HUMANS; HYPERTENSION; MALE; MICE; MICE, TRANSGENIC; MYOCYTES, CARDIAC; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES; TRANSCRIPTION FACTORS;

EID: 84930934938     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2015.04.012     Document Type: Article

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