Overexpression of a dominant-negative mutant of SIRT1 in mouse heart causes cardiomyocyte apoptosis and early-onset heart failure

Science China. Life sciences

Volumn 57, Issue 9, 2014, Pages 915-924

  Mu, WenLi ^a   Zhang, QingJun ^a   Tang, XiaoQiang ^a   Fu, WenYan ^a   Zheng, Wei ^a   Lu, YunBiao ^a   Li, HongLiang ^a   Wei, YuSheng ^a   Li, Li ^a   She, ZhiGang ^a   Chen, HouZao ^a   Liu, DePei ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BAX; PROTEIN P53; SIRT1 PROTEIN, MOUSE; SIRTUIN 1;

ACETYLATION; ANIMAL; APOPTOSIS; CELL CULTURE; CYTOLOGY; DOMINANT GENE; GENETICS; HEART FAILURE; HEART MUSCLE; HEART MUSCLE CELL; METABOLISM; MOUSE; ONSET AGE; PATHOLOGY; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; TRANSGENIC MOUSE;

ACETYLATION; AGE OF ONSET; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELLS, CULTURED; GENES, DOMINANT; HEART FAILURE; MICE; MICE, TRANSGENIC; MYOCARDIUM; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIRTUIN 1; TUMOR SUPPRESSOR PROTEIN P53;

EID: 85027917486     PISSN: None     EISSN: 18691889     Source Type: Journal    
DOI: 10.1007/s11427-014-4687-1     Document Type: Article

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