Clinical significance of intercellular contact at the four-cell stage of human embryos, and the use of abnormal cleavage patterns to identify embryos with low implantation potential: A time-lapse study

Fertility and Sterility

Volumn 103, Issue 6, 2015, Pages 1485-1491.e1

  Liu, Yanhe ^a,b   Chapple, Vincent ^a   Feenan, Katie ^a   Roberts, Peter ^b   Matson, Phillip ^a,b  

^a Joondalup Hospital   (Australia)

^b EDITH COWAN UNIVERSITY   (Australia)

Author keywords

abnormal cleavage; Embryo; in vitro fertilization; intercellular contact; time lapse

Indexed keywords

ADULT; ARTICLE; CELL CONTACT; CELL DIVISION; CELL KINETICS; CELL STRUCTURE; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; FERTILIZATION IN VITRO; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; NIDATION; PRIORITY JOURNAL; TIME LAPSE IMAGING; ANIMAL EMBRYO; CELL CULTURE; COHORT ANALYSIS; CYTOKINESIS; CYTOLOGY; DELAYED IMPLANTATION; EMBRYO TRANSFER; MICROSCOPY; OOCYTE CLEAVAGE; PHYSIOLOGY; PROCEDURES; RETROSPECTIVE STUDY;

ADULT; CELLS, CULTURED; CLEAVAGE STAGE, OVUM; COHORT STUDIES; CYTOKINESIS; EMBRYO IMPLANTATION, DELAYED; EMBRYO TRANSFER; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; FEMALE; FERTILIZATION IN VITRO; HUMANS; MICROSCOPY; RETROSPECTIVE STUDIES; TIME-LAPSE IMAGING;

EID: 84930928920     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2015.03.017     Document Type: Article

References (38)

1. I. Rubio, A. Galan, Z. Larreategui, F. Ayerdi, J. Bellver, and J. Herrero Clinical validation of embryo culture and selection by morphokinetic analysis: a randomized, controlled trial of the EmbryoScope Fertil Steril 102 2014 1287 1294.e5
2. M.D. VerMilyea, L. Tan, J.T. Anthony, J. Conaghan, K. Ivani, and M. Gvakharia Computer-automated time-lapse analysis results correlate with embryo implantation and clinical pregnancy: a blinded, multi-centre study Reprod Biomed Online 29 2014 729 736
3. M. Meseguer, J. Herrero, A. Tejera, K.M. Hilligsoe, N.B. Ramsing, and J. Remohi The use of morphokinetics as a predictor of embryo implantation Hum Reprod 26 2011 2658 2671
4. D.J. Kaser, and C. Racowsky Clinical outcomes following selection of human preimplantation embryos with time-lapse monitoring: a systematic review Hum Reprod Update 20 2014 617 631
5. C.C. Wong, K.E. Loewke, N.L. Bossert, B. Behr, C.J. De Jonge, and T.M. Baer Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage Nat Biotechnol 28 2010 1115 1121
6. M. Munoz, M. Cruz, P. Humaidan, N. Garrido, I. Perez-Cano, and M. Meseguer Dose of recombinant FSH and oestradiol concentration on day of HCG affect embryo development kinetics Reprod Biomed Online 25 2012 382 389
7. M. Munoz, M. Cruz, P. Humaidan, N. Garrido, I. Perez-Cano, and M. Meseguer The type of GnRH analogue used during controlled ovarian stimulation influences early embryo developmental kinetics: a time-lapse study Eur J Obstet Gynecol Reprod Biol 168 2013 167 172
8. T. Freour, L. Dessolle, J. Lammers, S. Lattes, and P. Barriere Comparison of embryo morphokinetics after in vitro fertilization-intracytoplasmic sperm injection in smoking and nonsmoking women Fertil Steril 99 2013 1944 1950
9. K. Kirkegaard, J.J. Hindkjaer, and H.J. Ingerslev Effect of oxygen concentration on human embryo development evaluated by time-lapse monitoring Fertil Steril 99 2013 738 744.e4
10. P.L. Wale, and D.K. Gardner Time-lapse analysis of mouse embryo development in oxygen gradients Reprod Biomed Online 21 2010 402 410
11. H.N. Ciray, T. Aksoy, C. Goktas, B. Ozturk, and M. Bahceci Time-lapse evaluation of human embryo development in single versus sequential culture media - a sibling oocyte study J Assist Reprod Genet 29 2012 891 900
12. E. Yalcinkaya, E.G. Ergin, E. Caliskan, Z. Oztel, A. Ozay, and H. Ozornek Reproducibility of a time-lapse embryo selection model based on morphokinetic data in a sequential culture media setting J Turk Ger Gynecol Assoc 15 2014 156 160
13. K. Kirkegaard, A. Ahlstrom, H.J. Ingerslev, and T. Hardarson Choosing the best embryo by time lapse versus standard morphology Fertil Steril 103 2015 323 332
14. L. Best, A. Campbell, S. Duffy, S. Montgomery, and S. Fishel Does one model fit all? Testing a published embryo selection algorithm on independent timelapse data Hum Reprod 28 Suppl 1 2013 i87 i90
15. K. Kirkegaard, A. Campbell, I. Agerholm, U. Bentin-Ley, A. Gabrielsen, and J. Kirk Limitations of a time-lapse blastocyst prediction model: a large multicentre outcome analysis Reprod Biomed Online 29 2014 156 158
16. M. Cetinkaya, C. Pirkevi, H. Yelke, Y.K. Colakoglu, Z. Atayurt, and S. Kahraman Relative kinetic expressions defining cleavage synchronicity are better predictors of blastocyst formation and quality than absolute time points J Assist Reprod Genet 32 2015 27 35
17. K. Athayde Wirka, A.A. Chen, J. Conaghan, K. Ivani, M. Gvakharia, and B. Behr Atypical embryo phenotypes identified by time-lapse microscopy: high prevalence and association with embryo development Fertil Steril 101 2014 1637 1648.e1-5
18. Y. Liu, V. Chapple, P. Roberts, and P. Matson Prevalence, consequence, and significance of reverse cleavage by human embryos viewed with the use of the Embryoscope time-lapse video system Fertil Steril 102 2014 1295 1300.e2
19. I. Rubio, R. Kuhlmann, I. Agerholm, J. Kirk, J. Herrero, and M.J. Escriba Limited implantation success of direct-cleaved human zygotes: a time-lapse study Fertil Steril 98 2012 1458 1463
20. G.M. Kidder, and E. Winterhager Intercellular communication in preimplantation development: the role of gap junctions Front Biosci 6 2001 D731 D736
21. J. Ding, N. Rana, and W.P. Dmowski Intracytoplasmic sperm injection into zona-free human oocytes results in normal fertilization and blastocyst development Hum Reprod 14 1999 476 478
22. T. Ebner, O. Shebl, M. Moser, M. Sommergruber, and G. Tews Developmental fate of ovoid oocytes Hum Reprod 23 2008 62 66
23. G. Cauffman, G. Verheyen, H. Tournaye, and H. Van de Velde Developmental capacity and pregnancy rate of tetrahedral- versus non-tetrahedral-shaped 4-cell stage human embryos J Assist Reprod Genet 31 2014 427 434
24. T. Ebner, M. Maurer, O. Shebl, M. Moser, R.B. Mayer, and H.C. Duba Planar embryos have poor prognosis in terms of blastocyst formation and implantation Reprod Biomed Online 25 2012 267 272
25. G. Paternot, S. Debrock, D. De Neubourg, T.M. D'Hooghe, and C. Spiessens The spatial arrangement of blastomeres at the 4-cell stage and IVF outcome Reprod Biomed Online 28 2014 198 203
26. T. Ebner, P. Oppelt, R.B. Mayer, and O. Shebl Developmental capacity and pregnancy rate of tetrahedral- versus non-tetrahedral-shaped 4-cell stage human embryos J Assist Reprod Genet 31 2014 621
27. M. Montag, J. Liebenthron, and M. Koster Which morphological scoring system is relevant in human embryo development? Placenta 32 Suppl 3 2011 S252 S256
28. M. Cruz, N. Garrido, B. Gadea, M. Munoz, I. Perez-Cano, and M. Meseguer Oocyte insemination techniques are related to alterations of embryo developmental timing in an oocyte donation model Reprod Biomed Online 27 2013 367 375
29. Alpha Scientists in Reproductive Medicine, ESHRE Special Interest Group of Embryology The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting Hum Reprod 26 2011 1270 1283
30. M. Alikani Epithelial cadherin distribution in abnormal human pre-implantation embryos Hum Reprod 20 2005 3369 3375
31. R.L. Gardner Experimental analysis of second cleavage in the mouse Hum Reprod 17 2002 3178 3189
32. B.S. Joo, S.H. Park, B.M. An, K.S. Kim, S.E. Moon, and H.S. Moon Serum estradiol levels during controlled ovarian hyperstimulation influence the pregnancy outcome of in vitro fertilization in a concentration-dependent manner Fertil Steril 93 2010 442 446
33. D. Valbuena, J. Martin, J.L. de Pablo, J. Remohi, A. Pellicer, and C. Simon Increasing levels of estradiol are deleterious to embryonic implantation because they directly affect the embryo Fertil Steril 76 2001 962 968
34. E.G. Ergin, E. Caliskan, E. Yalcinkaya, Z. Oztel, K. Cokelez, and A. Ozay Frequency of embryo multinucleation detected by time-lapse system and its impact on pregnancy outcome Fertil Steril 102 2014 1029 1033.e1
35. J.C. Arce, S. Ziebe, K. Lundin, R. Janssens, L. Helmgaard, and P. Sorensen Interobserver agreement and intraobserver reproducibility of embryo quality assessments Hum Reprod 21 2006 2141 2148
36. G. Paternot, J. Devroe, S. Debrock, T.M. D'Hooghe, and C. Spiessens Intra- and inter-observer analysis in the morphological assessment of early-stage embryos Reprod Biol Endocrinol 7 2009 105
37. L. Sundvall, H.J. Ingerslev, U. Breth Knudsen, and K. Kirkegaard Inter- and intra-observer variability of time-lapse annotations Hum Reprod 28 2013 3215 3221
38. Y. Liu, V. Chapple, P. Roberts, J. Ali, and P. Matson Time-lapse videography of human oocytes following intracytoplasmic sperm injection: events up to the first cleavage division Reprod Biol 14 2014 249 256