Studies on the contribution of human cytomegalovirus UL21a and UL97 to viral growth and inactivation of the anaphase-promoting complex/cyclosome (APC/C) E3 ubiquitin ligase reveal a unique cellular mechanism for downmodulation of the APC/C subunits APC1, APC4, and APC5

Journal of Virology

Volumn 89, Issue 13, 2015, Pages 6928-6939

  Clark, Elizabeth ^a   Spector, Deborah H ^b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE PROMOTING COMPLEX; ANAPHASE PROMOTING COMPLEX CYCLOSOME E3 UBIQUITIN LIGASE; ANAPHASE PROMOTING COMPLEX SUBUNIT 1; ANAPHASE PROMOTING COMPLEX SUBUNIT 4; ANAPHASE PROMOTING COMPLEX SUBUNIT 5; ANAPHASE PROMOTING COMPLEX SUBUNIT 8; SMALL INTERFERING RNA; UL21A PROTEIN; UL97 PROTEIN; UNCLASSIFIED DRUG; UBIQUITIN PROTEIN LIGASE; VIRAL PROTEIN;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SKIN FIBROBLAST; VIROGENESIS; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CYTOMEGALOVIRUS; HOST PATHOGEN INTERACTION; METABOLISM; PHYSIOLOGY; VIRUS REPLICATION;

HUMAN HERPESVIRUS 5;

APC1 SUBUNIT, ANAPHASE-PROMOTING COMPLEX-CYCLOSOME; APC4 SUBUNIT, ANAPHASE-PROMOTING COMPLEX-CYCLOSOME; APC5 SUBUNIT, ANAPHASE-PROMOTING COMPLEX-CYCLOSOME; CELLS, CULTURED; CYTOMEGALOVIRUS; HOST-PATHOGEN INTERACTIONS; HUMANS; UBIQUITIN-PROTEIN LIGASES; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84930922917     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00403-15     Document Type: Article

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