Inhibitory activity of curcumin derivatives towards metal-free and metal-induced amyloid-β aggregation

Current Alzheimer Research

Volumn 12, Issue 5, 2015, Pages 415-423

  Kochi, Akiko ^a,b   Lee, Hyuck Jin ^a,b   Vithanarachchi, Sashiprabha M ^c   Padmini, Vediappen ^d   Allen, Matthew J ^c   Lim, Mi Hee ^a,b  

^a Ulsan National Institute of Science and Technology   (South Korea)

^b UNIVERSITY OF MICHIGAN   (United States)

^c WAYNE STATE UNIVERSITY   (United States)

^d MADURAI KAMARAJ UNIVERSITY   (India)

Author keywords

Alzheimer s disease; Amyloid ; A aggregation control; Chemical reagents; Metal associated A ; Water soluble curcumin derivatives

Indexed keywords

AMYLOID BETA PROTEIN; CURCUMIN; METAL ION; MOLECULAR SCAFFOLD; ZINC ION; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA-PROTEIN (1-42); COPPER; GADOLINIUM; NEUROPROTECTIVE AGENT; PEPTIDE FRAGMENT; PROTEIN AGGREGATE; ZINC;

ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; CYTOTOXICITY; DRUG ACTIVITY; DRUG STRUCTURE; MEMBRANE PERMEABILITY; METAL BINDING; PRIORITY JOURNAL; PROTEIN AGGREGATION; ANALOGS AND DERIVATIVES; ANIMAL; CAPILLARY PERMEABILITY; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; METABOLISM; MOUSE; TUMOR CELL LINE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; BLOOD-BRAIN BARRIER; CAPILLARY PERMEABILITY; CELL LINE, TUMOR; CELL SURVIVAL; COPPER; CURCUMIN; GADOLINIUM; MICE; MOLECULAR STRUCTURE; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; PROTEIN AGGREGATES; ZINC;

EID: 84930905097     PISSN: 15672050     EISSN: 18755828     Source Type: Journal    
DOI: 10.2174/1567205012666150504150125     Document Type: Article

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